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5GP4
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BU of 5gp4 by Molmil
Lactobacillus brevis CGMCC 1306 Glutamate decarboxylase
Descriptor: Glutamate decarboxylase, PYRIDOXAL-5'-PHOSPHATE
Authors:Mei, L, Huang, J.
Deposit date:2016-07-31
Release date:2017-08-02
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.16 Å)
Cite:Lactobacillus brevis CGMCC 1306 glutamate decarboxylase: Crystal structure and functional analysis.
Biochem. Biophys. Res. Commun., 503, 2018
2OKK
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BU of 2okk by Molmil
The X-ray crystal structure of the 65kDa isoform of Glutamic Acid Decarboxylase (GAD65)
Descriptor: GAMMA-AMINO-BUTANOIC ACID, GLYCEROL, Glutamate decarboxylase 2
Authors:Buckle, A.M, Fenalti, G, Law, R.H.P, Whisstock, J.C.
Deposit date:2007-01-17
Release date:2007-03-27
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:GABA production by glutamic acid decarboxylase is regulated by a dynamic catalytic loop.
Nat.Struct.Mol.Biol., 14, 2007
7JZH
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BU of 7jzh by Molmil
The Cryo-EM structure of the Glutamate decarboxylase from Escherichia coli
Descriptor: Glutamate decarboxylase
Authors:Su, C.-C.
Deposit date:2020-09-02
Release date:2021-01-20
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.59 Å)
Cite:A 'Build and Retrieve' methodology to simultaneously solve cryo-EM structures of membrane proteins.
Nat.Methods, 18, 2021
2OKJ
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BU of 2okj by Molmil
The X-ray crystal structure of the 67kDa isoform of Glutamic Acid Decarboxylase (GAD67)
Descriptor: 4-[({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)AMINO]BUTANOIC ACID, GAMMA-AMINO-BUTANOIC ACID, Glutamate decarboxylase 1
Authors:Buckle, A.M, Fenalti, G, Law, R.H.P, Whisstock, J.C.
Deposit date:2007-01-17
Release date:2007-03-27
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:GABA production by glutamic acid decarboxylase is regulated by a dynamic catalytic loop.
Nat.Struct.Mol.Biol., 14, 2007
3VP6
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BU of 3vp6 by Molmil
Structural characterization of Glutamic Acid Decarboxylase; insights into the mechanism of autoinactivation
Descriptor: 4-oxo-4H-pyran-2,6-dicarboxylic acid, GLYCEROL, Glutamate decarboxylase 1
Authors:Langendorf, C.G, Tuck, K.L, Key, T.L.G, Rosado, C.J, Wong, A.S.M, Fenalti, G, Buckle, A.M, Law, R.H.P, Whisstock, J.C.
Deposit date:2012-02-27
Release date:2013-01-16
Last modified:2013-08-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural characterization of the mechanism through which human glutamic acid decarboxylase auto-activates
Biosci.Rep., 33, 2013
2DGL
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BU of 2dgl by Molmil
Crystal structure of Escherichia coli GadB in complex with bromide
Descriptor: ACETIC ACID, BROMIDE ION, Glutamate decarboxylase beta, ...
Authors:Gruetter, M.G, Capitani, G, Gut, H.
Deposit date:2006-03-14
Release date:2006-06-20
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Escherichia coli acid resistance: pH-sensing, activation by chloride and autoinhibition in GadB
Embo J., 25, 2006
2QMA
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BU of 2qma by Molmil
Crystal structure of glutamate decarboxylase domain of diaminobutyrate-pyruvate transaminase and L-2,4-diaminobutyrate decarboxylase from Vibrio parahaemolyticus
Descriptor: 1,2-ETHANEDIOL, Diaminobutyrate-pyruvate transaminase and L-2,4-diaminobutyrate decarboxylase
Authors:Osipiuk, J, Sather, A, Gu, M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
Deposit date:2007-07-14
Release date:2007-07-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.81 Å)
Cite:X-ray crystal structure of glutamate decarboxylase domain of diaminobutyrate-pyruvate transaminase and L-2,4-diaminobutyrate decarboxylase from Vibrio parahaemolyticus.
To be Published
2DGM
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BU of 2dgm by Molmil
Crystal structure of Escherichia coli GadB in complex with iodide
Descriptor: ACETIC ACID, DI(HYDROXYETHYL)ETHER, FORMIC ACID, ...
Authors:Gruetter, M.G, Capitani, G, Gut, H.
Deposit date:2006-03-14
Release date:2006-06-20
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Escherichia coli acid resistance: pH-sensing, activation by chloride and autoinhibition in GadB
Embo J., 25, 2006
2DGK
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BU of 2dgk by Molmil
Crystal structure of an N-terminal deletion mutant of Escherichia coli GadB in an autoinhibited state (aldamine)
Descriptor: 1,2-ETHANEDIOL, Glutamate decarboxylase beta, PYRIDOXAL-5'-PHOSPHATE, ...
Authors:Gruetter, M.G, Capitani, G, Gut, H.
Deposit date:2006-03-14
Release date:2006-06-20
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Escherichia coli acid resistance: pH-sensing, activation by chloride and autoinhibition in GadB
Embo J., 25, 2006
3FZ6
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BU of 3fz6 by Molmil
Crystal structure of glutamate decarboxylase beta from Escherichia coli: complex with xenon
Descriptor: 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, Glutamate decarboxylase beta, XENON
Authors:Malashkevich, V.N, De Biase, D, Bossa, F.
Deposit date:2009-01-23
Release date:2009-02-03
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.82 Å)
Cite:Crystal structure of glutamate decarboxylase beta from Escherichia coli: complex with xenon
To be Published
3FZ8
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BU of 3fz8 by Molmil
Crystal structure of glutamate decarboxylase beta from Escherichia coli: reduced Schiff base with PLP
Descriptor: (5-HYDROXY-4,6-DIMETHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE, Glutamate decarboxylase beta
Authors:Malashkevich, V.N, De Biase, D, Bossa, F.
Deposit date:2009-01-23
Release date:2009-02-03
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of glutamate decarboxylase beta from Escherichia coli: reduced Schiff base with PLP
to be published
3FZ7
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BU of 3fz7 by Molmil
Crystal structure of apo glutamate decarboxylase beta from Escherichia coli
Descriptor: Glutamate decarboxylase beta, PHOSPHATE ION
Authors:Malashkevich, V.N, De Biase, D, Bossa, F.
Deposit date:2009-01-23
Release date:2009-02-03
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of apo glutamate decarboxylase beta from Escherichia coli
To be Published
3HBX
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BU of 3hbx by Molmil
Crystal structure of GAD1 from Arabidopsis thaliana
Descriptor: Glutamate decarboxylase 1
Authors:Gut, H, Dominici, P, Pilati, S, Gruetter, M.G, Capitani, G.
Deposit date:2009-05-05
Release date:2009-07-28
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.672 Å)
Cite:A common structural basis for pH- and calmodulin-mediated regulation in plant glutamate decarboxylase.
J.Mol.Biol., 392, 2009
3K40
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BU of 3k40 by Molmil
Crystal structure of Drosophila 3,4-dihydroxyphenylalanine decarboxylase
Descriptor: Aromatic-L-amino-acid decarboxylase, GLYCEROL
Authors:Han, Q, Ding, H, Robinson, H, Christensen, B.M, Li, J.
Deposit date:2009-10-05
Release date:2010-02-02
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal structure and substrate specificity of Drosophila 3,4-dihydroxyphenylalanine decarboxylase
Plos One, 5, 2010
4Q6R
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BU of 4q6r by Molmil
Crystal structure of human sphingosine-1-phosphate lyase in complex with inhibitor 6-[(2R)-4-(4-benzyl-7-chlorophthalazin-1-yl)-2-methylpiperazin-1-yl]pyridine-3-carbonitrile
Descriptor: 6-[(2R)-4-(4-benzyl-7-chlorophthalazin-1-yl)-2-methylpiperazin-1-yl]pyridine-3-carbonitrile, GLYCEROL, PHOSPHATE ION, ...
Authors:Srinivas, H.
Deposit date:2014-04-23
Release date:2014-05-21
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Orally Active 7-Substituted (4-Benzylphthalazin-1-yl)-2-methylpiperazin-1-yl]nicotinonitriles as Active-Site Inhibitors of Sphingosine 1-Phosphate Lyase for the Treatment of Multiple Sclerosis.
J.Med.Chem., 57, 2014
3MAU
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BU of 3mau by Molmil
Crystal structure of StSPL in complex with phosphoethanolamine
Descriptor: (5-HYDROXY-4,6-DIMETHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE, PHOSPHATE ION, sphingosine-1-phosphate lyase, ...
Authors:Bourquin, F, Grutter, M.G, Capitani, G.
Deposit date:2010-03-24
Release date:2010-08-18
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure and Function of Sphingosine-1-Phosphate Lyase, a Key Enzyme of Sphingolipid Metabolism.
Structure, 18, 2010
3MAD
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BU of 3mad by Molmil
Crystal structure of StSPL (symmetric form)
Descriptor: PHOSPHATE ION, Sphingosine-1-phosphate lyase
Authors:Bourquin, F, Grutter, M.G, Capitani, G.
Deposit date:2010-03-23
Release date:2010-08-18
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure and Function of Sphingosine-1-Phosphate Lyase, a Key Enzyme of Sphingolipid Metabolism.
Structure, 18, 2010
3MBB
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BU of 3mbb by Molmil
Crystal structure of StSPL - apo form, after treatment with semicarbazide
Descriptor: 1,2-ETHANEDIOL, PHOSPHATE ION, Putative sphingosine-1-phosphate lyase, ...
Authors:Bourquin, F, Grutter, M.G, Capitani, G.
Deposit date:2010-03-25
Release date:2010-08-18
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.051 Å)
Cite:Structure and Function of Sphingosine-1-Phosphate Lyase, a Key Enzyme of Sphingolipid Metabolism.
Structure, 18, 2010
3MC6
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BU of 3mc6 by Molmil
Crystal structure of ScDPL1
Descriptor: PHOSPHATE ION, Sphingosine-1-phosphate lyase
Authors:Bourquin, F, Grutter, M.G, Capitani, G.
Deposit date:2010-03-27
Release date:2010-08-18
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Structure and Function of Sphingosine-1-Phosphate Lyase, a Key Enzyme of Sphingolipid Metabolism.
Structure, 18, 2010
7X4Y
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BU of 7x4y by Molmil
Crystal structure of Bacteroides thetaiotaomicron glutamate decarboxylase BTGAD-PLP-GABA complex
Descriptor: GAMMA-AMINO-BUTANOIC ACID, Glutamate decarboxylase, PYRIDOXAL-5'-PHOSPHATE
Authors:Liu, S, Du, G, Wang, Y, Wen, B, Xin, F.
Deposit date:2022-03-03
Release date:2023-04-05
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Coordinated regulation of Bacteroides thetaiotaomicron glutamate decarboxylase activity by multiple elements under different pH.
Food Chem, 403, 2023
7X52
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BU of 7x52 by Molmil
Crystal structure of Bacteroides thetaiotaomicron glutamate decarboxylase BTGAD-PLP complex
Descriptor: ACETATE ION, Glutamate decarboxylase, MALONATE ION, ...
Authors:Liu, S, Du, G, Wang, Y, Wen, B, Xin, F.
Deposit date:2022-03-03
Release date:2023-04-05
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Coordinated regulation of Bacteroides thetaiotaomicron glutamate decarboxylase activity by multiple elements under different pH.
Food Chem, 403, 2023
7X51
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BU of 7x51 by Molmil
Crystal structure of Bacteroides thetaiotaomicron glutamate decarboxylase BTGAD-PLP-GUA complex
Descriptor: GLUTARIC ACID, Glutamate decarboxylase, MALONATE ION, ...
Authors:Liu, S, Du, G, Wang, L, Wen, B, Xin, F.
Deposit date:2022-03-03
Release date:2023-04-19
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Coordinated regulation of Bacteroides thetaiotaomicron glutamate decarboxylase activity by multiple elements under different pH.
Food Chem, 403, 2023
7X4L
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BU of 7x4l by Molmil
Crystal structure of Bacteroides thetaiotaomicron glutamate decarboxylase mutant Y303F-PLP complex
Descriptor: Glutamate decarboxylase, PYRIDOXAL-5'-PHOSPHATE
Authors:Liu, S, Guoming, D, Yulu, W, Boting, W, Xin, F.
Deposit date:2022-03-02
Release date:2023-05-03
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:Coordinated regulation of Bacteroides thetaiotaomicron glutamate decarboxylase activity by multiple elements under different pH.
Food Chem, 403, 2023
7X4R
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BU of 7x4r by Molmil
Crystal structure of Bacteroides thetaiotaomicron glutamate decarboxylase
Descriptor: Glutamate decarboxylase
Authors:Liu, S, Wang, Y, Du, G, Wen, B, Xin, F.
Deposit date:2022-03-03
Release date:2023-09-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Coordinated regulation of Bacteroides thetaiotaomicron glutamate decarboxylase activity by multiple motifs
To Be Published
3MAF
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BU of 3maf by Molmil
Crystal structure of StSPL (asymmetric form)
Descriptor: CHLORIDE ION, PHOSPHATE ION, sphingosine-1-phosphate lyase
Authors:Bourquin, F, Grutter, M.G, Capitani, G.
Deposit date:2010-03-23
Release date:2010-08-18
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.971 Å)
Cite:Structure and Function of Sphingosine-1-Phosphate Lyase, a Key Enzyme of Sphingolipid Metabolism.
Structure, 18, 2010

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