6EXN
| Post-catalytic P complex spliceosome with 3' splice site docked | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, Intron lariat: UBC4 RNA, ... | 著者 | Wilkinson, M.E, Fica, S.M, Galej, W.P, Norman, C.M, Newman, A.J, Nagai, K. | 登録日 | 2017-11-08 | 公開日 | 2018-01-17 | 最終更新日 | 2020-10-07 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Postcatalytic spliceosome structure reveals mechanism of 3'-splice site selection. Science, 358, 2017
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6F4A
| Yeast mitochondrial RNA degradosome complex mtEXO | 分子名称: | Exoribonuclease II, mitochondrial, RNA (5'-R(P*AP*GP*AP*UP*AP*C)-3'), ... | 著者 | Razew, M, Nowak, E, Nowotny, M. | 登録日 | 2017-11-29 | 公開日 | 2018-01-17 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (3.55 Å) | 主引用文献 | Structural analysis of mtEXO mitochondrial RNA degradosome reveals tight coupling of nuclease and helicase components. Nat Commun, 9, 2018
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6BUA
| Drosophila Dicer-2 apo homology model (helicase, Platform-PAZ, RNaseIII domains) | 分子名称: | Dicer-2, isoform A | 著者 | Shen, P.S, Sinha, N.K, Bass, B.L. | 登録日 | 2017-12-09 | 公開日 | 2017-12-27 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (7.1 Å) | 主引用文献 | Dicer uses distinct modules for recognizing dsRNA termini. Science, 359, 2018
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6BU9
| Drosophila Dicer-2 bound to blunt dsRNA | 分子名称: | Dicer-2, isoform A, RNA (5'-R(*AP*CP*UP*AP*CP*UP*AP*UP*AP*CP*AP*AP*CP*CP*UP*AP*C)-3'), ... | 著者 | Shen, P.S, Sinha, N.K, Bass, B.L. | 登録日 | 2017-12-09 | 公開日 | 2017-12-27 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (6.8 Å) | 主引用文献 | Dicer uses distinct modules for recognizing dsRNA termini. Science, 359, 2018
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5YZG
| The Cryo-EM Structure of Human Catalytic Step I Spliceosome (C complex) at 4.1 angstrom resolution | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ... | 著者 | Zhan, X, Yan, C, Zhang, X, Lei, J, Shi, Y. | 登録日 | 2017-12-14 | 公開日 | 2018-08-08 | 最終更新日 | 2020-10-14 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Structure of a human catalytic step I spliceosome Science, 359, 2018
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6FA9
| CRYSTAL STRUCTURE OF THE DEAH-BOX HELICASE PRP2 | 分子名称: | Putative mRNA splicing factor, SULFATE ION | 著者 | Schmitt, A, Hamann, F, Neumann, P, Ficner, R. | 登録日 | 2017-12-15 | 公開日 | 2018-07-11 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Crystal structure of the spliceosomal DEAH-box ATPase Prp2. Acta Crystallogr D Struct Biol, 74, 2018
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6FAC
| CRYSTAL STRUCTURE OF THE DEAH-BOX HELICASE PRP2 IN COMPLEX WITH ADP | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, MAGNESIUM ION, ... | 著者 | Schmitt, A, Hamann, F, Neumann, P, Ficner, R. | 登録日 | 2017-12-15 | 公開日 | 2018-07-11 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Crystal structure of the spliceosomal DEAH-box ATPase Prp2. Acta Crystallogr D Struct Biol, 74, 2018
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6FA5
| CRYSTAL STRUCTURE OF THE DEAH-BOX HELICASE PRP2 IN COMPLEX WITH ADP | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, ... | 著者 | Hamann, F, Schmitt, A, Neumann, P, Ficner, R. | 登録日 | 2017-12-15 | 公開日 | 2018-07-11 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.303 Å) | 主引用文献 | Crystal structure of the spliceosomal DEAH-box ATPase Prp2. Acta Crystallogr D Struct Biol, 74, 2018
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6FAA
| CRYSTAL STRUCTURE OF THE DEAH-BOX HELICASE PRP2 IN COMPLEX WITH ADP | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ETHANOL, GLYCEROL, ... | 著者 | Schmitt, A, Hamann, F, Neumann, P, Ficner, R. | 登録日 | 2017-12-15 | 公開日 | 2018-07-11 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | 主引用文献 | Crystal structure of the spliceosomal DEAH-box ATPase Prp2. Acta Crystallogr D Struct Biol, 74, 2018
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6C0F
| Yeast nucleolar pre-60S ribosomal subunit (state 2) | 分子名称: | 5.8S rRNA, 60S ribosomal protein L13-A, 60S ribosomal protein L14-A, ... | 著者 | Sanghai, Z.A, Miller, L, Barandun, J, Hunziker, M, Chaker-Margot, M, Klinge, S. | 登録日 | 2017-12-29 | 公開日 | 2018-03-14 | 最終更新日 | 2020-01-08 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Modular assembly of the nucleolar pre-60S ribosomal subunit. Nature, 556, 2018
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6FF7
| human Bact spliceosome core structure | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-DIPHOSPHATE, BUD13 homolog, ... | 著者 | Haselbach, D, Komarov, I, Agafonov, D, Hartmuth, K, Graf, B, Kastner, B, Luehrmann, R, Stark, H. | 登録日 | 2018-01-03 | 公開日 | 2019-03-13 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | 主引用文献 | Structure and Conformational Dynamics of the Human Spliceosomal BactComplex. Cell, 172, 2018
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5Z3G
| Cryo-EM structure of a nucleolar pre-60S ribosome (Rpf1-TAP) | 分子名称: | 25S rRNA, 5.8S rRNA, 60S ribosomal protein L13-A, ... | 著者 | Zhu, X, Zhou, D, Ye, K. | 登録日 | 2018-01-06 | 公開日 | 2018-04-11 | 最終更新日 | 2019-11-06 | 実験手法 | ELECTRON MICROSCOPY (3.65 Å) | 主引用文献 | Cryo-EM structure of an early precursor of large ribosomal subunit reveals a half-assembled intermediate. Protein Cell, 10, 2019
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5Z56
| cryo-EM structure of a human activated spliceosome (mature Bact) at 5.1 angstrom. | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, BUD13 homolog, Cell division cycle 5-like protein, ... | 著者 | Zhang, X, Yan, C, Zhan, X, Li, L, Lei, J, Shi, Y. | 登録日 | 2018-01-17 | 公開日 | 2018-09-19 | 最終更新日 | 2020-10-14 | 実験手法 | ELECTRON MICROSCOPY (5.1 Å) | 主引用文献 | Structure of the human activated spliceosome in three conformational states. Cell Res., 28, 2018
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5Z58
| Cryo-EM structure of a human activated spliceosome (early Bact) at 4.9 angstrom. | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, BUD13 homolog, Cell division cycle 5-like protein, ... | 著者 | Zhang, X, Yan, C, Zhan, X, Li, L, Lei, J, Shi, Y. | 登録日 | 2018-01-17 | 公開日 | 2018-09-19 | 最終更新日 | 2020-10-14 | 実験手法 | ELECTRON MICROSCOPY (4.9 Å) | 主引用文献 | Structure of the human activated spliceosome in three conformational states. Cell Res., 28, 2018
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5Z57
| Cryo-EM structure of the human activated spliceosome (late Bact) at 6.5 angstrom | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, ALANINE, BUD13 homolog, ... | 著者 | Zhang, X, Yan, C, Zhan, X, Li, L, Lei, J, Shi, Y. | 登録日 | 2018-01-17 | 公開日 | 2018-09-19 | 最終更新日 | 2020-10-14 | 実験手法 | ELECTRON MICROSCOPY (6.5 Å) | 主引用文献 | Structure of the human activated spliceosome in three conformational states. Cell Res., 28, 2018
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6C90
| Human Mtr4 helicase in complex with ZCCHC8-CTD | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Exosome RNA helicase MTR4,Exosome RNA helicase MTR4, L(+)-TARTARIC ACID, ... | 著者 | Puno, M.R, Lima, C.D. | 登録日 | 2018-01-25 | 公開日 | 2018-05-30 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural basis for MTR4-ZCCHC8 interactions that stimulate the MTR4 helicase in the nuclear exosome-targeting complex. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6CB1
| Yeast nucleolar pre-60S ribosomal subunit (state 3) | 分子名称: | 35S pre-ribosomal RNA miscRNA, 5.8S rRNA, 60S ribosomal protein L13-A, ... | 著者 | Sanghai, Z.A, Miller, L, Barandun, J, Hunziker, M, Chaker-Margot, M, Klinge, S. | 登録日 | 2018-02-01 | 公開日 | 2018-03-14 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (4.6 Å) | 主引用文献 | Modular assembly of the nucleolar pre-60S ribosomal subunit. Nature, 556, 2018
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5ZAM
| Cryo-EM structure of human Dicer and its complexes with a pre-miRNA substrate | 分子名称: | Endoribonuclease Dicer, RISC-loading complex subunit TARBP2, RNA (73-mer) | 著者 | Liu, Z, Wang, J, Cheng, H, Ke, X, Sun, L, Zhang, Q.C, Wang, H.-W. | 登録日 | 2018-02-07 | 公開日 | 2018-05-09 | 最終更新日 | 2020-08-05 | 実験手法 | ELECTRON MICROSCOPY (5.7 Å) | 主引用文献 | Cryo-EM Structure of Human Dicer and Its Complexes with a Pre-miRNA Substrate. Cell, 173, 2018
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5ZAL
| Cryo-EM structure of human Dicer and its complexes with a pre-miRNA substrate | 分子名称: | Endoribonuclease Dicer, RISC-loading complex subunit TARBP2, RNA (73-mer) | 著者 | Liu, Z, Wang, J, Cheng, H, Ke, X, Sun, L, Zhang, Q.C, Wang, H.-W. | 登録日 | 2018-02-07 | 公開日 | 2018-05-09 | 最終更新日 | 2020-08-05 | 実験手法 | ELECTRON MICROSCOPY (4.7 Å) | 主引用文献 | Cryo-EM Structure of Human Dicer and Its Complexes with a Pre-miRNA Substrate. Cell, 173, 2018
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5ZAK
| Cryo-EM structure of human Dicer and its complexes with a pre-miRNA substrate | 分子名称: | Endoribonuclease Dicer, RISC-loading complex subunit TARBP2 | 著者 | Liu, Z, Wang, J, Cheng, H, Ke, X, Sun, L, Zhang, Q.C, Wang, H.-W. | 登録日 | 2018-02-07 | 公開日 | 2018-05-09 | 最終更新日 | 2019-11-06 | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | 主引用文献 | Cryo-EM Structure of Human Dicer and Its Complexes with a Pre-miRNA Substrate. Cell, 173, 2018
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5ZBZ
| Crystal structure of the DEAD domain of Human eIF4A with sanguinarine | 分子名称: | 13-methyl[1,3]benzodioxolo[5,6-c][1,3]dioxolo[4,5-i]phenanthridin-13-ium, Eukaryotic initiation factor 4A-I, MALONATE ION | 著者 | Ding, Y, Ding, L. | 登録日 | 2018-02-14 | 公開日 | 2019-02-20 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.30860257 Å) | 主引用文献 | Targeting the N Terminus of eIF4AI for Inhibition of Its Catalytic Recycling. Cell Chem Biol, 26, 2019
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5ZC9
| Crystal structure of the human eIF4A1-ATP analog-RocA-polypurine RNA complex | 分子名称: | (1R,2R,3S,3aR,8bS)-6,8-dimethoxy-3a-(4-methoxyphenyl)-N,N-dimethyl-1,8b-bis(oxidanyl)-3-phenyl-2,3-dihydro-1H-cyclopenta[b][1]benzofuran-2-carboxamide, Eukaryotic initiation factor 4A-I, MAGNESIUM ION, ... | 著者 | Iwasaki, W, Takahashi, M, Sakamoto, A, Iwasaki, S, Ito, T. | 登録日 | 2018-02-16 | 公開日 | 2019-01-16 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | The Translation Inhibitor Rocaglamide Targets a Bimolecular Cavity between eIF4A and Polypurine RNA. Mol. Cell, 73, 2019
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6FSZ
| Structure of the nuclear RNA exosome | 分子名称: | ATP-dependent RNA helicase DOB1, Exosome complex component CSL4, Exosome complex component MTR3, ... | 著者 | Schuller, J.M, Falk, S, Conti, E. | 登録日 | 2018-02-20 | 公開日 | 2018-03-21 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (4.6 Å) | 主引用文献 | Structure of the nuclear exosome captured on a maturing preribosome. Science, 360, 2018
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6FT6
| Structure of the Nop53 pre-60S particle bound to the exosome nuclear cofactors | 分子名称: | 25S ribosomal RNA, 5S ribosomal RNA, 60S ribosomal protein L11-A, ... | 著者 | Schuller, J.M, Falk, S, Conti, E. | 登録日 | 2018-02-20 | 公開日 | 2018-03-28 | 最終更新日 | 2019-12-11 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Structure of the nuclear exosome captured on a maturing preribosome. Science, 360, 2018
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6FWS
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