PDB: 253 件ウェブページステータス検索Chemie searchBIRD

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6M4I	Structure of CENP-E motor domain at 1.9 angstrom resolution 分子名称: ADENOSINE-5'-DIPHOSPHATE, Centromere-associated protein E, MAGNESIUM ION 著者 Shibuya, A, Yokoyama, H. 登録日 2020-03-07 公開日 2021-03-10 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structure and comparison of the motor domain ofcentromere-associated protein E Acta Crystallogr.,Sect.D, 77, 2021
2KIN	KINESIN (MONOMERIC) FROM RATTUS NORVEGICUS 分子名称: ADENOSINE-5'-DIPHOSPHATE, KINESIN, SULFATE ION 著者 Sack, S, Muller, J, Kozielski, F, Marx, A, Thormahlen, M, Biou, V, Mandelkow, E.-M, Brady, S.T, Mandelkow, E. 登録日 1997-04-28 公開日 1998-04-08 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 X-ray structure of motor and neck domains from rat brain kinesin. Biochemistry, 36, 1997
6NJE	Crystal structure of the motor domain of human kinesin family member 22 分子名称: ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, Kinesin-like protein KIF22, ... 著者 Walker, B.C, Zhu, H, Tempel, W, Arrowsmith, C.H, Edwards, A.M, Park, H, Cochran, J.C, Structural Genomics Consortium (SGC) 登録日 2019-01-03 公開日 2019-01-16 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structure of the motor domain of human kinesin family member 22 To Be Published
2NCD	NCD (NON-CLARET DISJUNCTIONAL) DIMER FROM D. MELANOGASTER 分子名称: ADENOSINE-5'-DIPHOSPHATE, PROTEIN (Kinesin motor NCD), SULFATE ION 著者 Sablin, E.P, Case, R.B, Dai, S.C, Hart, C.L, Ruby, A, Vale, R.D, Fletterick, R.J. 登録日 1999-06-04 公開日 1999-06-09 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Direction determination in the minus-end-directed kinesin motor ncd. Nature, 395, 1998
1VFV	Crystal Structure of the Kif1A Motor Domain Complexed With Mg-AMPPNP 分子名称: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, PROTEIN (Fusion protein consisting of Kinesin-like protein KIF1A, ... 著者 Nitta, R, Kikkawa, M, Okada, Y, Hirokawa, N. 登録日 2004-04-19 公開日 2004-08-10 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 KIF1A Alternately Uses Two Loops to Bind Microtubules Science, 305, 2004
1VFX	Crystal Structure of the Kif1A Motor Domain Complexed With ADP-Mg-AlFx 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, ... 著者 Nitta, R, Kikkawa, M, Okada, Y, Hirokawa, N. 登録日 2004-04-19 公開日 2004-08-10 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 KIF1A Alternately Uses Two Loops to Bind Microtubules Science, 305, 2004
1VFW	Crystal Structure of the Kif1A Motor Domain Complexed With Mg-AMPPNP 分子名称: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, PROTEIN (Fusion protein consisting of Kinesin-like protein KIF1A, ... 著者 Nitta, R, Kikkawa, M, Okada, Y, Hirokawa, N. 登録日 2004-04-19 公開日 2004-08-10 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 KIF1A Alternately Uses Two Loops to Bind Microtubules Science, 305, 2004
1VFZ	Crystal Structure of the Kif1A Motor Domain Complexed With ADP-Mg-VO4 分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PROTEIN (Fusion protein consisting of Kinesin-like protein KIF1A, ... 著者 Nitta, R, Kikkawa, M, Okada, Y, Hirokawa, N. 登録日 2004-04-19 公開日 2004-08-10 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.24 Å) 主引用文献 KIF1A Alternately Uses Two Loops to Bind Microtubules Science, 305, 2004
4UBF	HsMCAK motor domain complex 分子名称: ADENOSINE-5'-DIPHOSPHATE, Kinesin-like protein KIF2C, MAGNESIUM ION 著者 Welburn, J.P.I, Talapatra, S.K. 登録日 2014-08-12 公開日 2015-05-06 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 The C-terminal region of the motor protein MCAK controls its structure and activity through a conformational switch. Elife, 4, 2015
1Q0B	Crystal structure of the motor protein KSP in complex with ADP and monastrol 分子名称: ADENOSINE-5'-DIPHOSPHATE, ETHYL 4-(3-HYDROXYPHENYL)-6-METHYL-2-THIOXO-1,2,3,4-TETRAHYDROPYRIMIDINE-5-CARBOXYLATE, Kinesin-like protein KIF11, ... 著者 Yan, Y, Sardana, V, Xu, B, Halczenko, W, Homnick, C, Buser, C.A, Hartman, G.D, Huber, H.E, Kuo, L.C. 登録日 2003-07-15 公開日 2004-01-13 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Inhibition of a mitotic motor protein: where, how, and conformational consequences J.Mol.Biol., 335, 2004
1X88	Human Eg5 motor domain bound to Mg-ADP and monastrol 分子名称: ADENOSINE-5'-DIPHOSPHATE, ETHYL 4-(3-HYDROXYPHENYL)-6-METHYL-2-THIOXO-1,2,3,4-TETRAHYDROPYRIMIDINE-5-CARBOXYLATE, Kinesin-like protein KIF11, ... 著者 Maliga, Z, Mitchison, T.J. 登録日 2004-08-17 公開日 2005-11-15 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural Basis of Eg5 Inhibition by Monastrol TO BE PUBLISHED
1RY6	Crystal Structure of Internal Kinesin Motor Domain 分子名称: INTERNAL KINESIN, SULFATE ION 著者 Shipley, K, Hekmat-Nejad, M, Turner, J, Moores, C, Anderson, R, Milligan, R, Sakowicz, R, Fletterick, R. 登録日 2003-12-19 公開日 2004-04-13 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structure of a kinesin microtubule depolymerization machine. Embo J., 23, 2004
1SDM	Crystal structure of kinesin-like calmodulin binding protein 分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, kinesin heavy chain-like protein 著者 Vinogradova, M.V, Reddy, V.S, Reddy, A.S, Sablin, E.P, Fletterick, R.J. 登録日 2004-02-13 公開日 2004-06-22 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structure of kinesin regulated by Ca(2+)-calmodulin. J.Biol.Chem., 279, 2004
1YRS	Crystal structure of KSP in complex with inhibitor 1 分子名称: 3-[(5S)-1-ACETYL-3-(2-CHLOROPHENYL)-4,5-DIHYDRO-1H-PYRAZOL-5-YL]PHENOL, ADENOSINE-5'-DIPHOSPHATE, Kinesin-like protein KIF11, ... 著者 Cox, C.D, Breslin, M.J, Mariano, B.J, Coleman, P.J, Buser, C.A, Walsh, E.S, Hamilton, K, Kohl, N.E, Torrent, M, Yan, Y, Kuo, L.C, Hartman, G.D. 登録日 2005-02-04 公開日 2005-04-12 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Kinesin spindle protein (KSP) inhibitors. Part 1: The discovery of 3,5-diaryl-4,5-dihydropyrazoles as potent and selective inhibitors of the mitotic kinesin KSP BIOORG.MED.CHEM.LETT., 15, 2005
1T5C	Crystal structure of the motor domain of human kinetochore protein CENP-E 分子名称: ADENOSINE-5'-DIPHOSPHATE, Centromeric protein E, MAGNESIUM ION, ... 著者 Garcia-Saez, I, Yen, T, Wade, R.H, Kozielski, F, Structural Proteomics in Europe (SPINE) 登録日 2004-05-04 公開日 2005-05-10 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structure of the motor domain of the human kinetochore protein CENP-E. J.Mol.Biol., 340, 2004
1V8J	The Crystal Structure of the Minimal Functional Domain of the Microtubule Destabilizer KIF2C Complexed with Mg-ADP 分子名称: ADENOSINE-5'-DIPHOSPHATE, Kinesin-like protein KIF2C, MAGNESIUM ION 著者 Ogawa, T, Nitta, R, Okada, Y, Hirokawa, N. 登録日 2004-01-09 公開日 2004-03-02 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (3.24 Å) 主引用文献 A common mechanism for microtubule destabilizers-M type kinesins stabilize curling of the protofilament using the class-specific neck and loops. Cell(Cambridge,Mass.), 116, 2004
1V8K	The Crystal Structure of the Minimal Functional Domain of the Microtubule Destabilizer KIF2C Complexed with Mg-AMPPNP 分子名称: Kinesin-like protein KIF2C, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER 著者 Ogawa, T, Nitta, R, Okada, Y, Hirokawa, N. 登録日 2004-01-09 公開日 2004-03-02 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 A common mechanism for microtubule destabilizers-M type kinesins stabilize curling of the protofilament using the class-specific neck and loops. Cell(Cambridge,Mass.), 116, 2004
8HFH	CENP-E motor domain in complex with AMPPNP and Mg2+ 分子名称: Centromere-associated protein E, IMIDAZOLE, MAGNESIUM ION, ... 著者 Shibuya, A, Yokoyama, H. 登録日 2022-11-10 公開日 2023-03-08 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structure of the motor domain of centromere-associated protein E in complex with a non-hydrolysable ATP analogue. Febs Lett., 597, 2023
6TRL	Human Eg5 motor domain mutant Y82F 分子名称: ADENOSINE-5'-DIPHOSPHATE, DI(HYDROXYETHYL)ETHER, Kinesin-like protein KIF11, ... 著者 Garcia-Saez, I, Skoufias, D.A. 登録日 2019-12-19 公開日 2021-06-30 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Human Eg5 motor domain mutant Y82F To Be Published
6TLE	Human Eg5 motor domain mutant E344K 分子名称: ADENOSINE-5'-DIPHOSPHATE, Kinesin-like protein KIF11, MAGNESIUM ION, ... 著者 Garcia-Saez, I, Skoufias, D.A. 登録日 2019-12-02 公開日 2021-06-30 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Human Eg5 motor domain mutant E344K To Be Published
7LFF	Crystal structure of the Candida albicans kinesin-8 motor domain 分子名称: ADENOSINE-5'-DIPHOSPHATE, Kinesin-like protein, MAGNESIUM ION 著者 Allingham, J.S, Hunter, B. 登録日 2021-01-16 公開日 2022-02-09 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 Kinesin-8-specific loop-2 controls the dual activities of the motor domain according to tubulin protofilament shape. Nat Commun, 13, 2022
7LXR	Kinesin-like protein at 61F (Klp61f) bound to AMPPNP 分子名称: 1,2-ETHANEDIOL, IODIDE ION, Kinesin-like protein Klp61F, ... 著者 Worthylake, D.K, Wojcik, E.J. 登録日 2021-03-04 公開日 2022-11-16 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.744 Å) 主引用文献 Crystal Structure of the Klp61f motor domain bound to AMPPNP To Be Published
5GSY	Kinesin-8 motor, KIF19A, in the nucleotide-free state complexed with GDP-taxol microtubule 分子名称: Kinesin-like protein KIF19 著者 Morikawa, M, Nitta, R, Yajima, H, Shigematsu, H, Kikkawa, M, Hirokawa, N. 登録日 2016-08-17 公開日 2016-09-28 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (7 Å) 主引用文献 Motility and microtubule depolymerization mechanisms of the Kinesin-8 motor, KIF19A Elife, 5, 2016
5GSZ	Crystal Structure of the KIF19A Motor Domain Complexed with Mg-ADP 分子名称: ADENOSINE-5'-DIPHOSPHATE, Kinesin-like protein KIF19, MAGNESIUM ION 著者 Wang, D, Nitta, R, Hirokawa, N. 登録日 2016-08-18 公開日 2016-09-28 最終更新日 2020-02-26 実験手法 X-RAY DIFFRACTION (2.72 Å) 主引用文献 Motility and microtubule depolymerization mechanisms of the Kinesin-8 motor, KIF19A Elife, 5, 2016
5HLE	Structural basis of backwards motion in kinesin-14: minus-end directed nKn664 in the ADP state 分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Protein claret segregational,Minus-end kinesin-1/kinesin-14,Protein claret segregational 著者 Nitta, R. 登録日 2016-01-14 公開日 2017-01-25 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Backwards motion in kinesin-14 requires neck-mimic to control a neck-helix swing. To Be Published

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