1V8K

The Crystal Structure of the Minimal Functional Domain of the Microtubule Destabilizer KIF2C Complexed with Mg-AMPPNP

Summary for 1V8K

Entry DOI	10.2210/pdb1v8k/pdb
Related	1V8J
Descriptor	Kinesin-like protein KIF2C, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... (4 entities in total)
Functional Keywords	kinesin-like protein, microtubule destabilizer, structural protein
Biological source	Mus musculus (house mouse)
Cellular location	Cytoplasm, cytoskeleton (By similarity): Q922S8
Total number of polymer chains	1
Total formula weight	47333.21
Authors	Ogawa, T.,Nitta, R.,Okada, Y.,Hirokawa, N. (deposition date: 2004-01-09, release date: 2004-03-02, Last modification date: 2023-12-27)
Primary citation	Ogawa, T.,Nitta, R.,Okada, Y.,Hirokawa, N. A common mechanism for microtubule destabilizers-M type kinesins stabilize curling of the protofilament using the class-specific neck and loops. Cell(Cambridge,Mass.), 116:591-602, 2004 Cited by PubMed: 14980225 DOI: 10.1016/S0092-8674(04)00129-1 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.25 Å)

Structure validation