1V8K

The Crystal Structure of the Minimal Functional Domain of the Microtubule Destabilizer KIF2C Complexed with Mg-AMPPNP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Kinesin-like protein KIF2C	polymer	410	46802.7	1	UniProt (Q922S8) Pfam (PF00225) In PDB	Mus musculus (house mouse)	Mitotic centromere-associated kinesin, MCAK
2	A	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG)
3	A	PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER	non-polymer		506.2	1	Chemie (ANP)
4		water	water		18.0	111	Chemie (HOH)

Sequence modifications

A: 1 - 403 (UniProt: Q922S8)

PDB	External Database	Details
His 404	-	expression tag
His 405	-	expression tag
His 406	-	expression tag
His 407	-	expression tag
His 408	-	expression tag
His 409	-	expression tag
His 410	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	46802.7
Non-Polymers*	Number of molecules	2
	Total formula weight	530.5
All*	Total formula weight	47333.2

*Water molecules are not included.