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1V8K

The Crystal Structure of the Minimal Functional Domain of the Microtubule Destabilizer KIF2C Complexed with Mg-AMPPNP

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Kinesin-like protein KIF2Cpolymer41046802.71UniProt (Q922S8)
Pfam (PF00225)
Mus musculus (house mouse)Mitotic centromere-associated kinesin, MCAK
2B
(A)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
PubChem (888)
3C
(A)
PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTERnon-polymer506.21Chemie (ANP)
PubChem (4795)
PubChem (33113)
PubChem (445863)
PubChem (6102784)
PubChem (9543492)
PubChem (14188278)
PubChem (16058657)
PubChem (23639785)
PubChem (24794410)
PubChem (44462678)
PubChem (46926537)
PubChem (54765332)
PubChem (60063697)
PubChem (66575078)
PubChem (89688694)
PubChem (92436779)
PubChem (93005803)
4D
(A)
waterwater18.0111Chemie (HOH)
Sequence modifications
A: 1 - 403 (UniProt: Q922S8)
PDBExternal DatabaseDetails
His 404-expression tag
His 405-expression tag
His 406-expression tag
His 407-expression tag
His 408-expression tag
His 409-expression tag
His 410-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight46802.7
Non-Polymers*Number of molecules2
Total formula weight530.5
All*Total formula weight47333.2
*Water molecules are not included.

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PDB entries from 2026-03-25

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