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5NX8	Crystal structure of Neanderthal Adenylosuccinate Lyase (ADSL) Descriptor: Adenylosuccinate lyase, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... Authors: Van Laer, B, Kapp, U, Soler-Lopez, M, Leonard, G, Mueller-Dieckmann, C. Deposit date: 2017-05-09 Release date: 2018-05-30 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Molecular comparison of Neanderthal and Modern Human adenylosuccinate lyase. Sci Rep, 8, 2018
4NLE	Crystal structure of apo Adenylosuccinate Lyase from Mycobacterium smegmatis Descriptor: Adenylosuccinate lyase Authors: Banerjee, S, Murthy, M.R.N. Deposit date: 2013-11-14 Release date: 2014-03-05 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.16 Å) Cite: Structural and kinetic studies on adenylosuccinate lyase from Mycobacterium smegmatis and Mycobacterium tuberculosis provide new insights on the catalytic residues of the enzyme. Febs J., 281, 2014
3E04	Crystal structure of human fumarate hydratase Descriptor: 1,2-ETHANEDIOL, Fumarate hydratase Authors: Kavanagh, K.L, Oppermann, U, Structural Genomics Consortium (SGC) Deposit date: 2008-07-30 Release date: 2008-08-12 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Crystal structure of human fumarate hydratase TO BE PUBLISHED
6U4O	Crystal structure of recombinant class II fumarase from Schistosoma mansoni Descriptor: (2S)-2-hydroxybutanedioic acid, ACETATE ION, Fumarate hydratase, ... Authors: Cardoso, I.A, Nonato, M.C. Deposit date: 2019-08-26 Release date: 2020-09-02 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Characterization of class II fumarase from Schistosoma mansoni provides the molecular basis for selective inhibition. Int.J.Biol.Macromol., 175, 2021
7T24	Crystal Structure of Adenylosuccinate lyase (ASL) from Pseudomonas aeruginosa Descriptor: Adenylosuccinate lyase, IMIDAZOLE, ISOPROPYL ALCOHOL Authors: Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2021-12-03 Release date: 2021-12-15 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.45 Å) Cite: Crystal Structure of Adenylosuccinate lyase (ASL) from Pseudomonas aeruginosa to be published
7T29	Crystal Structure of Adenylosuccinate lyase (ASL) from Pseudomonas aeruginosa complexed with AMP Descriptor: 1,2-ETHANEDIOL, ADENOSINE MONOPHOSPHATE, Adenylosuccinate lyase Authors: Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2021-12-03 Release date: 2021-12-15 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Crystal Structure of Adenylosuccinate lyase (ASL) from Pseudomonas aeruginosa complexed with AMP to be published
6EBT	Crystal structure of recombinant mutant N107T of human fumarase Descriptor: Fumarate hydratase, mitochondrial, GLYCEROL Authors: Ajalla, M.A.A, Nonato, M.C. Deposit date: 2018-08-07 Release date: 2019-08-21 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Crystal structure of recombinant mutant N107T of human fumarase To Be Published
7T93	Crystal Structure of Fumarate hydratase class II from Mycobacterium ulcerans in complex with L-Malate Descriptor: (2S)-2-hydroxybutanedioic acid, (4S)-2-METHYL-2,4-PENTANEDIOL, Fumarate hydratase class II Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2021-12-17 Release date: 2022-04-13 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Crystal Structure of Fumarate hydratase class II from Mycobacterium ulcerans in complex with L-Malate to be published
7C1C	Crystal structure of FumaraseC from Mannheimia succiniciproducens Descriptor: Fumarate hydratase class II, GLYCEROL Authors: Kim, B, Lee, S.H, Kim, K.-J. Deposit date: 2020-05-02 Release date: 2021-05-05 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Structural and Biochemical analysis of FumaraseC from Mannheimia succiniciproducens To Be Published
7C18	Crystal structure of FumaraseC from Mannheimia succiniciproducens in complex with Fumarate Descriptor: FUMARIC ACID, Fumarate hydratase class II Authors: Kim, B, Lee, S.H, Kim, K.-J. Deposit date: 2020-05-02 Release date: 2021-05-05 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.12 Å) Cite: Structural studies reveal the molecular mechanism of isocitrate lyase from Chloroflexus aurantiacus To Be Published
7C1A	Crystal structure of FumaraseC (S319C) from Mannheimia succiniciproducens in complex with malate Descriptor: (2S)-2-hydroxybutanedioic acid, Fumarate hydratase class II Authors: Kim, B, Lee, S.H, Kim, K.-J. Deposit date: 2020-05-02 Release date: 2021-05-05 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.144 Å) Cite: Structural and Biochemical analysis of FumaraseC from Mannheimia succiniciproducens To Be Published
6V8F	Crystal structure of recombinat mutant Q185R of human fumarase Descriptor: CHLORIDE ION, Fumarate hydratase, mitochondrial, ... Authors: Ajalla, M.A.A, Nonato, M.C. Deposit date: 2019-12-11 Release date: 2020-12-16 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Crystal structure of recombinat mutant Q185R of human fumarase To Be Published
6VBE	Crystal structure of recombinant mutant H180R of human fumarase Descriptor: Fumarate hydratase, mitochondrial, GLYCEROL, ... Authors: Ajalla, M.A.A, Nonato, M.C. Deposit date: 2019-12-18 Release date: 2020-12-23 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.899 Å) Cite: Crystal structure of recombinant mutant H180R of human fumarase To Be Published
5V4L	Cryptococcus neoformans adenylosuccinate lyase Descriptor: Adenylosuccinate lyase Authors: Chitty, J, Williams, S.J, Kobe, B, Fraser, J.A. Deposit date: 2017-03-09 Release date: 2017-06-07 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Cryptococcus neoformans ADS lyase is an enzyme essential for virulence whose crystal structure reveals features exploitable in antifungal drug design. J. Biol. Chem., 292, 2017
5UPP	Crystal structure of human fumarate hydratase Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Fumarate hydratase, mitochondrial Authors: Rangel, V.L, Ajalla, M.A, Rustiguel, J.K, Pereira de Padua, R.A, Nonato, M.C. Deposit date: 2017-02-03 Release date: 2018-02-07 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Structural, biochemical and biophysical characterization of recombinant human fumarate hydratase. Febs J., 2019
6G3G	Crystal structure of EDDS lyase in complex with succinate Descriptor: Argininosuccinate lyase, DI(HYDROXYETHYL)ETHER, SUCCINIC ACID Authors: Poddar, H, Thunnissem, A.M.W.H, Poelarends, G.J. Deposit date: 2018-03-25 Release date: 2018-05-16 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.606 Å) Cite: Structural Basis for the Catalytic Mechanism of Ethylenediamine- N, N'-disuccinic Acid Lyase, a Carbon-Nitrogen Bond-Forming Enzyme with a Broad Substrate Scope. Biochemistry, 57, 2018
6G3E	Crystal structure of EDDS lyase in complex with formate Descriptor: Argininosuccinate lyase, FORMIC ACID, SODIUM ION Authors: Poddar, H, Thunnissem, A.M.W.H, Poelarends, G.J. Deposit date: 2018-03-25 Release date: 2018-05-16 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structural Basis for the Catalytic Mechanism of Ethylenediamine- N, N'-disuccinic Acid Lyase, a Carbon-Nitrogen Bond-Forming Enzyme with a Broad Substrate Scope. Biochemistry, 57, 2018
5VKW	Crystal structure of adenylosuccinate lyase ADE13 from Candida albicans Descriptor: Adenylosuccinate lyase, CALCIUM ION, CHLORIDE ION, ... Authors: Stogios, P.J, Evdokimova, E, Di Leo, R, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) Deposit date: 2017-04-24 Release date: 2017-05-24 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.998 Å) Cite: Crystal structure of adenylosuccinate lyase ADE13 from Candida albicans To Be Published
3GTD	2.4 Angstrom crystal structure of fumarate hydratase from Rickettsia prowazekii Descriptor: Fumarate hydratase class II, MALONATE ION, SODIUM ION Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2009-03-27 Release date: 2009-07-14 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Structure of fumarate hydratase from Rickettsia prowazekii, the agent of typhus and suspected relative of the mitochondria. Acta Crystallogr.,Sect.F, 67, 2011
3GZH	Crystal structure of phosphate-bound adenylosuccinate lyase from E. coli Descriptor: Adenylosuccinate lyase, PHOSPHATE ION, SODIUM ION Authors: Kozlov, G, Gehring, K, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) Deposit date: 2009-04-07 Release date: 2009-08-25 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.9 Å) Cite: The structure of phosphate-bound Escherichia coli adenylosuccinate lyase identifies His171 as a catalytic acid. Acta Crystallogr.,Sect.F, 65, 2009
1JSW	NATIVE L-ASPARTATE AMMONIA LYASE Descriptor: ACETATE ION, L-ASPARTATE AMMONIA-LYASE, beta-D-glucopyranose Authors: Shi, W, Dunbar, J, Farber, G.K. Deposit date: 1997-02-19 Release date: 1997-06-16 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.7 Å) Cite: The structure of L-aspartate ammonia-lyase from Escherichia coli. Biochemistry, 36, 1997
1K62	Crystal Structure of the Human Argininosuccinate Lyase Q286R Mutant Descriptor: Argininosuccinate Lyase Authors: Sampaleanu, L.M, Vallee, F, Thompson, G.D, Howell, P.L. Deposit date: 2001-10-14 Release date: 2002-02-01 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (2.65 Å) Cite: Three-dimensional structure of the argininosuccinate lyase frequently complementing allele Q286R. Biochemistry, 40, 2001
1K7W	Crystal Structure of S283A Duck Delta 2 Crystallin Mutant Descriptor: ARGININOSUCCINATE, delta 2 crystallin Authors: Sampaleanu, L.M, Yu, B, Howell, P.L. Deposit date: 2001-10-22 Release date: 2002-03-06 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (1.96 Å) Cite: Mutational analysis of duck delta 2 crystallin and the structure of an inactive mutant with bound substrate provide insight into the enzymatic mechanism of argininosuccinate lyase. J.Biol.Chem., 277, 2002
1KQ7	E315Q Mutant Form of Fumarase C from E.coli Descriptor: CITRIC ACID, D-MALATE, FUMARATE HYDRATASE CLASS II Authors: Weaver, T.M, Estevez, M, Skarda, J, Spencer, J. Deposit date: 2002-01-04 Release date: 2002-08-23 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (2.6 Å) Cite: X-ray crystallographic and kinetic correlation of a clinically observed human fumarase mutation. Protein Sci., 11, 2002
2E9F	Crystal Structure of T.th.HB8 Argininosuccinate lyase complexed with L-Arginine Descriptor: ARGININE, Argininosuccinate lyase Authors: Goto, M. Deposit date: 2007-01-25 Release date: 2007-07-31 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Crystal Structure of T.th.HB8 Argininosuccinate lyase complexed with L-Arginine To be published

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