1K62

Crystal Structure of the Human Argininosuccinate Lyase Q286R Mutant

Summary for 1K62

Entry DOI	10.2210/pdb1k62/pdb
Related	1AOS 1AUW 1DCN 1HY0 1HY1 1I0A
Descriptor	Argininosuccinate Lyase (2 entities in total)
Functional Keywords	intragenic complementation, arginiosuccinate lyase, delta crystallin, enzyme mechanism, lyase
Biological source	Homo sapiens (human)
Total number of polymer chains	2
Total formula weight	103868.33
Authors	Sampaleanu, L.M.,Vallee, F.,Thompson, G.D.,Howell, P.L. (deposition date: 2001-10-14, release date: 2002-02-01, Last modification date: 2023-08-16)
Primary citation	Sampaleanu, L.M.,Vallee, F.,Thompson, G.D.,Howell, P.L. Three-dimensional structure of the argininosuccinate lyase frequently complementing allele Q286R. Biochemistry, 40:15570-15580, 2001 Cited by PubMed: 11747432 DOI: 10.1021/bi011525m PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.65 Å)

Structure validation