PDB: 229 件ウェブページステータス検索Chemie searchBIRD

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2DHT	Crystal structure of isocitrate dehydrogenase from Sulfolobus tokodaii strain7 分子名称: 409aa long hypothetical NADP-dependent isocitrate dehydrogenase 著者 Kondo, H, Murakami, M, Ihara, K, Suzuki, S, Kouyama, T. 登録日 2006-03-25 公開日 2007-03-27 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structure of isocitrate dehydrogenase of Sulfolobus tokodaii strain7 To be Published
2E0C	crystal structure of isocitrate dehydrogenase from Sulfolobus tokodaii strain7 at 2.0 A resolution 分子名称: 409aa long hypothetical NADP-dependent isocitrate dehydrogenase 著者 Kouyama, T. 登録日 2006-10-06 公開日 2007-10-30 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal Structures of the Putative Isocitrate Dehydrogenase fromSulfolobus tokodaiiStrain 7 in the Apo and NADP+-Bound Forms. Archaea, 2018, 2018
2E5M	Crystal structure of isocitrate dehydrogenase from Sulfolobus tokodaii strain 7 分子名称: 409aa long hypothetical NADP-dependent isocitrate dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Kouyama, T, Kondo, H. 登録日 2006-12-22 公開日 2008-01-15 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal Structures of the Putative Isocitrate Dehydrogenase fromSulfolobus tokodaiiStrain 7 in the Apo and NADP+-Bound Forms. Archaea, 2018, 2018
4L04	Crystal Structure Analysis of human IDH1 mutants in complex with NADP+ and Ca2+/alpha-Ketoglutarate 分子名称: 2-OXOGLUTARIC ACID, CALCIUM ION, Isocitrate dehydrogenase [NADP] cytoplasmic, ... 著者 Concha, N.O, Smallwood, A.M. 登録日 2013-05-30 公開日 2013-07-31 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.87 Å) 主引用文献 Mutant IDH1 Enhances the Production of 2-Hydroxyglutarate Due to Its Kinetic Mechanism. Biochemistry, 52, 2013
4KZO	Crystal Structure Analysis of human IDH1 mutants in complex with NADP+ and Ca2+/alpha-Ketoglutarate 分子名称: 1,2-ETHANEDIOL, 2-OXOGLUTARIC ACID, CALCIUM ION, ... 著者 Concha, N.O, Smallwood, A.M. 登録日 2013-05-30 公開日 2013-07-17 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.204 Å) 主引用文献 Mutant IDH1 Enhances the Production of 2-Hydroxyglutarate Due to Its Kinetic Mechanism. Biochemistry, 52, 2013
4L06	Crystal Structure Analysis of human IDH1 mutants in complex with NADP+ and Ca2+/alpha-Ketoglutarate 分子名称: 2-OXOGLUTARIC ACID, CALCIUM ION, Isocitrate dehydrogenase [NADP] cytoplasmic, ... 著者 Concha, N.O, Smallwood, A.M. 登録日 2013-05-30 公開日 2013-07-24 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.282 Å) 主引用文献 Mutant IDH1 Enhances the Production of 2-Hydroxyglutarate Due to Its Kinetic Mechanism. Biochemistry, 52, 2013
4L03	Crystal Structure Analysis of human IDH1 mutants in complex with NADP+ and Ca2+/alpha-Ketoglutarate 分子名称: 1,2-ETHANEDIOL, 2-OXOGLUTARIC ACID, CALCIUM ION, ... 著者 Concha, N.O, Smallwood, A.M. 登録日 2013-05-30 公開日 2013-07-17 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Mutant IDH1 Enhances the Production of 2-Hydroxyglutarate Due to Its Kinetic Mechanism. Biochemistry, 52, 2013
2G4O	anomalous substructure of 3-ISOPROPYLMALATE DEHYDROGENASE 分子名称: 3-isopropylmalate dehydrogenase, CHLORIDE ION, SULFATE ION 著者 Mueller-Dieckmann, C, Weiss, M.S. 登録日 2006-02-22 公開日 2007-02-20 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 On the routine use of soft X-rays in macromolecular crystallography. Part IV. Efficient determination of anomalous substructures in biomacromolecules using longer X-ray wavelengths. Acta Crystallogr.,Sect.D, 63, 2007
2IV0	Thermal stability of isocitrate dehydrogenase from Archaeoglobus fulgidus studied by crystal structure analysis and engineering of chimers 分子名称: CHLORIDE ION, ISOCITRATE DEHYDROGENASE, ZINC ION 著者 Stokke, R, Karlstrom, M, Yang, N, Leiros, I, Ladenstein, R, Birkeland, N.K, Steen, I.H. 登録日 2006-06-08 公開日 2007-04-17 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Thermal Stability of Isocitrate Dehydrogenase from Archaeoglobus Fulgidus Studied by Crystal Structure Analysis and Engineering of Chimers Extremophiles, 11, 2007
2Y3Z	Structure of Isopropylmalate dehydrogenase from Thermus thermophilus - apo enzyme 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3-ISOPROPYLMALATE DEHYDROGENASE, GLYCEROL, ... 著者 Graczer, E, merlin, A, Singh, R.K, Manikandan, K, Zavodsky, P, Weiss, M.S, Vas, M. 登録日 2011-01-04 公開日 2011-01-19 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.83 Å) 主引用文献 Atomic Level Description of the Domain Closure in a Dimeric Enzyme: Thermus Thermophilus 3-Isopropylmalate Dehydrogenase. Mol.Biosyst., 7, 2011
2Y41	Structure of Isopropylmalate dehydrogenase from Thermus thermophilus - complex with IPM and MN 分子名称: 3-ISOPROPYLMALATE DEHYDROGENASE, 3-ISOPROPYLMALIC ACID, MANGANESE (II) ION 著者 Graczer, E, merlin, A, Singh, R.K, Manikandan, K, Zavodsky, P, Weiss, M.S, Vas, M. 登録日 2011-01-04 公開日 2011-01-19 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Atomic Level Description of the Domain Closure in a Dimeric Enzyme: Thermus Thermophilus 3-Isopropylmalate Dehydrogenase. Mol.Biosyst., 7, 2011
2QFY	Crystal structure of Saccharomyces cerevesiae mitochondrial NADP(+)-dependent isocitrate dehydrogenase in complex with a-ketoglutarate 分子名称: 2-OXOGLUTARIC ACID, Isocitrate dehydrogenase [NADP] 著者 Peng, Y.J, Ding, J.P. 登録日 2007-06-28 公開日 2008-07-01 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural studies of Saccharomyces cerevesiae mitochondrial NADP-dependent isocitrate dehydrogenase in different enzymatic states reveal substantial conformational changes during the catalytic reaction Protein Sci., 17, 2008
8GRG	Crystal structure of a constitutively active mutant of the alpha gamma heterodimer of human IDH3 分子名称: Human IDH3 alpha subunit, Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial 著者 Sun, P, Chen, X, Ding, J. 登録日 2022-09-01 公開日 2022-11-30 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.699 Å) 主引用文献 Structures of a constitutively active mutant of human IDH3 reveal new insights into the mechanisms of allosteric activation and the catalytic reaction. J.Biol.Chem., 298, 2022
8GS5	Crystal structure of a constitutively active mutant of human IDH3 holoenzyme in apo form 分子名称: Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial, Isocitrate dehydrogenase [NAD] subunit gamma, ... 著者 Sun, P, Chen, X, Ding, J. 登録日 2022-09-04 公開日 2022-11-30 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (4.486 Å) 主引用文献 Structures of a constitutively active mutant of human IDH3 reveal new insights into the mechanisms of allosteric activation and the catalytic reaction. J.Biol.Chem., 298, 2022
8GRU	Crystal structure of a constitutively active mutant of the alpha beta heterodimer of human IDH3 in complex with ICT, NAD and Ca 分子名称: CALCIUM ION, Human IDH3 alpha subunit, ISOCITRIC ACID, ... 著者 Sun, P, Chen, X, Ding, J. 登録日 2022-09-02 公開日 2022-11-30 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.847 Å) 主引用文献 Structures of a constitutively active mutant of human IDH3 reveal new insights into the mechanisms of allosteric activation and the catalytic reaction. J.Biol.Chem., 298, 2022
8GRD	Crystal structure of a constitutively active mutant of the alpha beta heterodimer of human IDH3 in complex with ADP and Mg 分子名称: ADENOSINE-5'-DIPHOSPHATE, Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial, ... 著者 Chen, X, Sun, P, Ding, J. 登録日 2022-09-01 公開日 2022-11-30 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.699 Å) 主引用文献 Structures of a constitutively active mutant of human IDH3 reveal new insights into the mechanisms of allosteric activation and the catalytic reaction. J.Biol.Chem., 298, 2022
8GRH	Crystal structure of a constitutively active mutant of the alpha gamma heterodimer of human IDH3 in complex with CIT 分子名称: CITRIC ACID, Human IDH3 alpha subunit, Isocitrate dehydrogenase [NAD] subunit gamma, ... 著者 Sun, P, Chen, X, Ding, J. 登録日 2022-09-01 公開日 2022-11-30 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.506 Å) 主引用文献 Structures of a constitutively active mutant of human IDH3 reveal new insights into the mechanisms of allosteric activation and the catalytic reaction. J.Biol.Chem., 298, 2022
2QFV	Crystal structure of Saccharomyces cerevesiae mitochondrial NADP(+)-dependent isocitrate dehydrogenase in complex with NADP(+) 分子名称: Isocitrate dehydrogenase [NADP], NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Peng, Y.J, Ding, J.P. 登録日 2007-06-28 公開日 2008-07-01 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural studies of Saccharomyces cerevesiae mitochondrial NADP-dependent isocitrate dehydrogenase in different enzymatic states reveal substantial conformational changes during the catalytic reaction Protein Sci., 17, 2008
8GRB	Crystal structure of a constitutively active mutant of the alpha beta heterodimer of human IDH3 分子名称: Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial, Isoform A of Isocitrate dehydrogenase [NAD] subunit beta 著者 Sun, P, Chen, X, Ding, J. 登録日 2022-09-01 公開日 2022-12-07 最終更新日 2022-12-21 実験手法 X-RAY DIFFRACTION (2.848 Å) 主引用文献 Structures of a constitutively active mutant of human IDH3 reveal new insights into the mechanisms of allosteric activation and the catalytic reaction. J.Biol.Chem., 298, 2022
2QFX	Crystal structure of Saccharomyces cerevesiae mitochondrial NADP(+)-dependent isocitrate dehydrogenase in complex with NADPH, a-ketoglutarate and Ca(2+) 分子名称: 2-OXOGLUTARIC ACID, CALCIUM ION, Isocitrate dehydrogenase [NADP], ... 著者 Peng, Y.J, Ding, J.P. 登録日 2007-06-28 公開日 2008-07-01 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural studies of Saccharomyces cerevesiae mitochondrial NADP-dependent isocitrate dehydrogenase in different enzymatic states reveal substantial conformational changes during the catalytic reaction Protein Sci., 17, 2008
2QFW	Crystal structure of Saccharomyces cerevesiae mitochondrial NADP(+)-dependent isocitrate dehydrogenase in complex with isocitrate 分子名称: ISOCITRIC ACID, Isocitrate dehydrogenase [NADP] 著者 Peng, Y.J, Ding, J.P. 登録日 2007-06-28 公開日 2008-07-01 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural studies of Saccharomyces cerevesiae mitochondrial NADP-dependent isocitrate dehydrogenase in different enzymatic states reveal substantial conformational changes during the catalytic reaction Protein Sci., 17, 2008
2ZTW	Structure of 3-isopropylmalate dehydrogenase in complex with the inhibitor and NAD+ 分子名称: (2Z)-2-hydroxy-3-(methylsulfanyl)prop-2-enoic acid, 3-isopropylmalate dehydrogenase, MAGNESIUM ION, ... 著者 Nango, E, Kumasaka, T, Eguchi, T. 登録日 2008-10-10 公開日 2009-10-13 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.79 Å) 主引用文献 Crystal structure of 3-isopropylmalate dehydrogenase in complex with NAD(+) and a designed inhibitor Bioorg.Med.Chem., 17, 2009
8HB9	Crystal Structure of Human IDH1 R132H Mutant in Complex with NADPH and Compound IHMT-IDH1-053 分子名称: DI(HYDROXYETHYL)ETHER, GLYCEROL, Isocitrate dehydrogenase [NADP] cytoplasmic, ... 著者 Guo, G, Wang, B, Liu, J, Liu, Q. 登録日 2022-10-27 公開日 2023-05-24 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structure-based discovery of IHMT-IDH1-053 as a potent irreversible IDH1 mutant selective inhibitor. Eur.J.Med.Chem., 256, 2023
2UXQ	Isocitrate dehydrogenase from the psychrophilic bacterium Desulfotalea psychrophila: biochemical properties and crystal structure analysis 分子名称: DI(HYDROXYETHYL)ETHER, GLYCEROL, ISOCITRATE DEHYDROGENASE NATIVE, ... 著者 Fedoy, A.-E, Yang, N, Martinez, A, Leiros, H.-K.S, Steen, I.H. 登録日 2007-03-29 公開日 2008-02-05 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Structural and Functional Properties of Isocitrate Dehydrogenase from the Psychrophilic Bacterium Desulfotalea Psychrophila Reveal a Cold -Active Enzyme with an Unusual High Thermal J.Mol.Biol., 372, 2007
8ICD	REGULATION OF AN ENZYME BY PHOSPHORYLATION AT THE ACTIVE SITE 分子名称: ISOCITRATE DEHYDROGENASE, ISOCITRIC ACID, MAGNESIUM ION 著者 Hurley, J.H, Dean, A.M, Sohl, J.L, Koshlandjunior, D.E, Stroud, R.M. 登録日 1990-05-30 公開日 1991-10-15 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Regulation of an enzyme by phosphorylation at the active site. Science, 249, 1990

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