PDB: 367 件ウェブページステータス検索Chemie searchBIRD

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7N09	Structural basis for branched substrate selectivity in a ketoreductase from Ascaris suum 分子名称: 3-hydroxyacyl-CoA dehydrogenase type-2, NICOTINAMIDE-ADENINE-DINUCLEOTIDE 著者 Dong, H, Chang, M.C.Y. 登録日 2021-05-25 公開日 2021-08-11 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural Basis for Branched Substrate Selectivity in a Ketoreductase from Ascaris suum Acs Catalysis, 11, 2021
7E3X	Crystal structure of SDR family NAD(P)-dependent oxidoreductase from exiguobacterium 分子名称: NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Oxidoreductase 著者 Chen, L, Tang, J, Yuan, S, Zhang, F, Chen, S. 登録日 2021-02-09 公開日 2021-09-29 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.58 Å) 主引用文献 Structure-guided evolution of a ketoreductase forefficient and stereoselective bioreduction of bulkyalpha-aminobeta-keto esters Catalysis Science And Technology, 2021
7E24	Crystal structure of SDR family NAD(P)-dependent oxidoreductase from Exiguobacterium 分子名称: NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Oxidoreductase 著者 Chen, L, Tang, J, Yuan, S. 登録日 2021-02-04 公開日 2021-09-29 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.7203 Å) 主引用文献 Structure-guided evolution of a ketoreductase forefficient and stereoselective bioreduction of bulkyalpha-aminobeta-keto esters Catalysis Science And Technology, 2021
7E28	Crystal structure of SDR family NAD(P)-dependent oxidoreductase from Exiguobacterium 分子名称: Oxidoreductase 著者 Chen, L, Tang, J, Yuan, S. 登録日 2021-02-05 公開日 2021-09-29 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.83 Å) 主引用文献 Structure-guided evolution of a ketoreductase forefficient and stereoselective bioreduction of bulkyalpha-aminobeta-keto esters Catalysis Science And Technology, 2021
7BTM	SDR protein/resistance protein NapW 分子名称: Short chain dehydrogenase 著者 Wen, W.H, Tang, G.L. 登録日 2020-04-02 公開日 2021-10-06 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.08311653 Å) 主引用文献 Reductive inactivation of the hemiaminal pharmacophore for resistance against tetrahydroisoquinoline antibiotics. Nat Commun, 12, 2021
7BSX	SDR protein NapW-NADP 分子名称: NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Short chain dehydrogenase 著者 Wen, W.H, Tang, G.L. 登録日 2020-03-31 公開日 2021-10-06 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Reductive inactivation of the hemiaminal pharmacophore for resistance against tetrahydroisoquinoline antibiotics. Nat Commun, 12, 2021
7E6O	Crystal structure of polyol dehydrogenase from Paracoccus denitrificans 分子名称: Short-chain dehydrogenase/reductase SDR 著者 Sha, F, Zheng, Y.C. 登録日 2021-02-22 公開日 2022-03-02 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structure of polyol dehydrogenase from Paracoccus denitrificans To Be Published
7ULH	Crystal Structure of a Short chain dehydrogenase from Mycobacterium avium 104 分子名称: Short chain dehydrogenase 著者 Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2022-04-04 公開日 2022-04-13 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Crystal Structure of Crystal Structure of a Short chain dehydrogenase from Mycobacterium avium 104 to be published
8DT1	Crystal Structure of a Putative D-beta-hydroxybutyrate dehydrogenase from Burkholderia cenocepacia J2315 in complex with NAD 分子名称: 3-hydroxybutyrate dehydrogenase, CITRIC ACID, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2022-07-25 公開日 2022-08-17 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal Structure of a Putative D-beta-hydroxybutyrate dehydrogenase from Burkholderia cenocepacia J2315 in complex with NAD To Be Published
8B5T	Crystal structure of Quinonoid dihydropteridine reductase from Leishmania major 分子名称: Quinonoid dihydropteridine reductase 著者 Robinson, D.A, Fairlamb, A.H. 登録日 2022-09-24 公開日 2022-10-05 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structure of Quinonoid dihydropteridine reductase from Leishmania major To Be Published
8B5U	Crystal structure of Quinonoid dihydropteridine reductase from Leishmania donovani 分子名称: Quinonoid dihydropteridine reductase 著者 Robinson, D.A, Fairlamb, A.H. 登録日 2022-09-24 公開日 2022-10-19 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structure of Quinonoid dihydropteridine reductase from Leishmania donovani To Be Published
7X3Z	Crystal structure of human 17beta-hydroxysteroid dehydrogenase type 1 complexed with estrone and NAD 分子名称: (9beta,13alpha)-3-hydroxyestra-1,3,5(10)-trien-17-one, 17-beta-hydroxysteroid dehydrogenase type 1, NICOTINAMIDE-ADENINE-DINUCLEOTIDE 著者 Li, T, Lin, S.X, Yin, H. 登録日 2022-03-01 公開日 2023-01-25 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 New insights into the substrate inhibition of human 17 beta-hydroxysteroid dehydrogenase type 1. J.Steroid Biochem.Mol.Biol., 228, 2023
8CVN	Cryo-EM Structure of Human 15-PGDH in Complex with Small Molecule SW209415 分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 15-hydroxyprostaglandin dehydrogenase [NAD(+)], 2-[butyl(oxidanyl)-$l^{3}-sulfanyl]-4-(2,3-dimethylimidazol-4-yl)-6-(1,3-thiazol-2-yl)thieno[2,3-b]pyridin-3-amine 著者 Huang, W, Taylor, D.J. 登録日 2022-05-18 公開日 2023-03-01 最終更新日 2023-03-29 実験手法 ELECTRON MICROSCOPY (2.4 Å) 主引用文献 Small molecule inhibitors of 15-PGDH exploit a physiologic induced-fit closing system. Nat Commun, 14, 2023
8FD8	human 15-PGDH with NADH bound 分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 15-hydroxyprostaglandin dehydrogenase [NAD(+)] 著者 Huang, W, Taylor, D. 登録日 2022-12-02 公開日 2023-03-08 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Small molecule inhibitors of 15-PGDH exploit a physiologic induced-fit closing system. Nat Commun, 14, 2023
8CWL	Cryo-EM structure of Human 15-PGDH in complex with small molecule SW222746 分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 15-hydroxyprostaglandin dehydrogenase [NAD(+)], 2-methyl-6-[7-(piperidine-1-carbonyl)quinoxalin-2-yl]isoquinolin-1(2H)-one 著者 Huang, W, Taylor, D.J. 登録日 2022-05-19 公開日 2023-03-08 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Small molecule inhibitors of 15-PGDH exploit a physiologic induced-fit closing system. Nat Commun, 14, 2023
7X5J	ACP-dependent oxoacyl reductase 分子名称: 3-oxoacyl-ACP reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, PHENYLALANINE 著者 Wang, S, Bai, L. 登録日 2022-03-04 公開日 2023-03-08 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 ACP-dependent oxoacyl reductase To Be Published
8AEQ	Malonyl-CoA reductase from Chloroflexus aurantiacus - C-terminal R773Q variant 分子名称: Short-chain dehydrogenase/reductase SDR 著者 Kabasakal, B.V, Murray, J.W. 登録日 2022-07-13 公開日 2023-04-05 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.64 Å) 主引用文献 Dynamic lid domain of Chloroflexus aurantiacus Malonyl-CoA reductase controls the reaction. Biochimie, 219, 2023
8AEO	Malonyl-CoA reductase from Chloroflexus aurantiacus - C-terminal R773A variant 分子名称: SULFATE ION, Short-chain dehydrogenase/reductase SDR 著者 Kabasakal, B.V, Murray, J.W. 登録日 2022-07-13 公開日 2023-04-05 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.76 Å) 主引用文献 Dynamic lid domain of Chloroflexus aurantiacus Malonyl-CoA reductase controls the reaction. Biochimie, 219, 2023
8AET	Malonyl-CoA reductase from Chloroflexus aurantiacus - C-terminal E779W variant 分子名称: SULFATE ION, Short-chain dehydrogenase/reductase SDR 著者 Kabasakal, B.V, Murray, J.W. 登録日 2022-07-13 公開日 2023-04-05 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Dynamic lid domain of Chloroflexus aurantiacus Malonyl-CoA reductase controls the reaction. Biochimie, 219, 2023
8A8T	Malonyl-CoA reductase from Chloroflexus aurantiacus - C-terminal NADP and malonate bound 分子名称: MALONATE ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Short-chain dehydrogenase/reductase SDR 著者 Kabasakal, B.V, Murray, J.W. 登録日 2022-06-24 公開日 2023-04-05 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.11 Å) 主引用文献 Dynamic lid domain of Chloroflexus aurantiacus Malonyl-CoA reductase controls the reaction. Biochimie, 219, 2023
8A7S	Malonyl-CoA reductase from Chloroflexus aurantiacus - C-terminal NADP bound 分子名称: MAGNESIUM ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Short-chain dehydrogenase/reductase SDR 著者 Kabasakal, B.V, Murray, J.W. 登録日 2022-06-21 公開日 2023-04-05 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.542 Å) 主引用文献 Dynamic lid domain of Chloroflexus aurantiacus Malonyl-CoA reductase controls the reaction. Biochimie, 219, 2023
8AEW	Malonyl-CoA reductase from Chloroflexus aurantiacus - N-terminal Apo 分子名称: Short-chain dehydrogenase/reductase SDR 著者 Kabasakal, B.V, Murray, J.W. 登録日 2022-07-13 公開日 2023-04-05 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.72 Å) 主引用文献 Dynamic lid domain of Chloroflexus aurantiacus Malonyl-CoA reductase controls the reaction. Biochimie, 219, 2023
8A30	Malonyl-CoA reductase from Chloroflexus aurantiacus - C-terminal Apo 分子名称: MAGNESIUM ION, Short-chain dehydrogenase/reductase SDR 著者 Kabasakal, B.V, Murray, J.W. 登録日 2022-06-06 公開日 2023-04-05 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Dynamic lid domain of Chloroflexus aurantiacus Malonyl-CoA reductase controls the reaction. Biochimie, 219, 2023
8AER	Malonyl-CoA reductase from Chloroflexus aurantiacus - C-terminal Y731A variant 分子名称: MAGNESIUM ION, Short-chain dehydrogenase/reductase SDR 著者 Kabasakal, B.V, Murray, J.W. 登録日 2022-07-13 公開日 2023-04-05 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.77 Å) 主引用文献 Dynamic lid domain of Chloroflexus aurantiacus Malonyl-CoA reductase controls the reaction. Biochimie, 219, 2023
8HI4	Cryo-EM structure of the bi-functional malonyl-CoA reductase from Roseiflexus castenholzii 分子名称: Short-chain dehydrogenase/reductase SDR 著者 Zhang, X, Xu, X, Xin, J. 登録日 2022-11-18 公開日 2023-05-31 最終更新日 2023-09-20 実験手法 ELECTRON MICROSCOPY (3.35 Å) 主引用文献 Structural basis of a bi-functional malonyl-CoA reductase (MCR) from the photosynthetic green non-sulfur bacterium Roseiflexus castenholzii. Mbio, 14, 2023

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