5E6S
 
 | | Structures of leukocyte integrin aLB2: The aI domain, the headpiece, and the pocket for the internal ligand | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Integrin alpha-L, ... | | 著者 | Springer, T.A, Sen, M. | | 登録日 | 2015-10-10 | | 公開日 | 2016-03-02 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Leukocyte integrin alpha L beta 2 headpiece structures: The alpha I domain, the pocket for the internal ligand, and concerted movements of its loops.
Proc.Natl.Acad.Sci.USA, 113, 2016
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5HJ2
 | | Integrin alpha2beta1 I-domain | | 分子名称: | CALCIUM ION, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Brown, K.L, Banerjee, S. | | 登録日 | 2016-01-12 | | 公開日 | 2017-04-12 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.153 Å) | | 主引用文献 | Salt-bridge modulates differential calcium-mediated ligand binding to integrin alpha 1- and alpha 2-I domains.
Sci Rep, 8, 2018
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8FZ4
 | | The von Willebrand factor A domain of Anthrax toxin receptor 2 | | 分子名称: | Anthrax toxin receptor 2, CHLORIDE ION, MAGNESIUM ION | | 著者 | Pedroza-Romo, M.J, Soleimani, S, Lewis, A, Smith, T, Brown, S, Doukov, T, Moody, J.D. | | 登録日 | 2023-01-27 | | 公開日 | 2023-03-01 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | | 主引用文献 | Increasing the bulk of the 1TEL-target linker and retaining the 10×His tag in a 1TEL-CMG2-vWa construct improves crystal order and diffraction limits.
Acta Crystallogr D Struct Biol, 79, 2023
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4HQO
 | | Crystal structure of Plasmodium vivax TRAP protein | | 分子名称: | CHLORIDE ION, MAGNESIUM ION, SODIUM ION, ... | | 著者 | Song, G, Koksal, A.C, Lu, C, Springer, T.A. | | 登録日 | 2012-10-25 | | 公開日 | 2012-12-26 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.194 Å) | | 主引用文献 | Shape change in the receptor for gliding motility in Plasmodium sporozoites.
Proc.Natl.Acad.Sci.USA, 109, 2012
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4HQN
 | | Crystal structure of manganese-loaded Plasmodium vivax TRAP protein | | 分子名称: | CHLORIDE ION, MANGANESE (II) ION, Sporozoite surface protein 2, ... | | 著者 | Song, G, Koksal, A.C, Lu, C, Springer, T.A. | | 登録日 | 2012-10-25 | | 公開日 | 2012-12-26 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.196 Å) | | 主引用文献 | Shape change in the receptor for gliding motility in Plasmodium sporozoites.
Proc.Natl.Acad.Sci.USA, 109, 2012
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1AO3
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6SNK
 | | Crystal structure of the Collagen VI alpha3 N2 domain | | 分子名称: | Collagen alpha-3(VI) chain | | 著者 | Gebauer, J.M, Degefa, H.S, Paulsson, M, Wagener, R, Baumann, U. | | 登録日 | 2019-08-26 | | 公開日 | 2020-07-29 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structure of a collagen VI alpha 3 chain VWA domain array: adaptability and functional implications of myopathy causing mutations.
J.Biol.Chem., 295, 2020
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1XDD
 | | X-ray structure of LFA-1 I-domain in complex with LFA703 at 2.2A resolution | | 分子名称: | 8-[2-((2S)-4-HYDROXY-1-{[5-(HYDROXYMETHYL)-6-METHOXY-2-NAPHTHYL]METHYL}-6-OXOPIPERIDIN-2-YL)ETHYL]-3,7-DIMETHYL-1,2,3,7,8,8A-HEXAHYDRONAPHTHALEN-1-YL 2-METHYLBUTANOATE, Integrin alpha-L, MAGNESIUM ION | | 著者 | Weitz-Schmidt, G, Welzenbach, K, Dawson, J, Kallen, J. | | 登録日 | 2004-09-06 | | 公開日 | 2004-09-21 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Improved lymphocyte function-associated antigen-1 (LFA-1) inhibition by statin derivatives: molecular basis determined by x-ray analysis and monitoring of LFA-1 conformational changes in vitro and ex vivo
J.Biol.Chem., 279, 2004
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1CK4
 | | CRYSTAL STRUCTURE OF RAT A1B1 INTEGRIN I-DOMAIN. | | 分子名称: | INTEGRIN ALPHA-1 | | 著者 | Nolte, M, Pepinsky, R.B, Venyaminov, S.Y, Koteliansky, V, Gotwals, P.J, Karpusas, M. | | 登録日 | 1999-04-27 | | 公開日 | 2000-05-03 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal structure of the alpha1beta1 integrin I-domain: insights into integrin I-domain function.
FEBS Lett., 452, 1999
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1OAK
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6FPZ
 | | Inter-alpha-inhibitor heavy chain 1, D298A | | 分子名称: | ACETATE ION, GLYCEROL, Inter-alpha-trypsin inhibitor heavy chain H1 | | 著者 | Briggs, D.C, Day, A.J. | | 登録日 | 2018-02-12 | | 公開日 | 2019-02-27 | | 最終更新日 | 2020-03-18 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Inter-alpha-inhibitor heavy chain-1 has an integrin-like 3D structure mediating immune regulatory activities and matrix stabilization during ovulation
J.Biol.Chem., 2020
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3HRZ
 | | Cobra Venom Factor (CVF) in complex with human factor B | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cobra venom factor, ... | | 著者 | Janssen, B.J.C, Gomes, L, Koning, R.I, Svergun, D.I, Koster, A.J, Fritzinger, D.C, Vogel, C.-W, Gros, P. | | 登録日 | 2009-06-10 | | 公開日 | 2009-07-07 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Insights into complement convertase formation based on the structure of the factor B-cobra venom factor complex
Embo J., 28, 2009
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2B2X
 | | VLA1 RdeltaH I-domain complexed with a quadruple mutant of the AQC2 Fab | | 分子名称: | Antibody AQC2 Fab, Integrin alpha-1, MAGNESIUM ION | | 著者 | Clark, L.A, Boriack-Sjodin, P.A, Eldredge, J, Fitch, C, Friedman, B, Hanf, K.J, Jarpe, M, Liparoto, S.F, Li, Y, Lugovskoy, A. | | 登録日 | 2005-09-19 | | 公開日 | 2006-04-18 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Affinity enhancement of an in vivo matured therapeutic antibody using structure-based computational design
Protein Sci., 15, 2006
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4HQF
 | | Crystal structure of Plasmodium falciparum TRAP, I4 form | | 分子名称: | CHLORIDE ION, Thrombospondin-related anonymous protein, TRAP | | 著者 | Song, G, Koksal, A.C, Lu, C, Springer, T.A. | | 登録日 | 2012-10-25 | | 公開日 | 2012-12-26 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Shape change in the receptor for gliding motility in Plasmodium sporozoites.
Proc.Natl.Acad.Sci.USA, 109, 2012
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4C29
 | | Crystal Structure of High-Affinity von Willebrand Factor A1 domain with Disulfide Mutation | | 分子名称: | ACETATE ION, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Blenner, M.A, Dong, X, Springer, T.A. | | 登録日 | 2013-08-16 | | 公開日 | 2014-01-08 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.202 Å) | | 主引用文献 | Towards the Structural Basis of Regulation of Von Willebrand Factor Binding to Glycoprotein Ib
J.Biol.Chem., 289, 2014
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4HQL
 | | Crystal structure of magnesium-loaded Plasmodium vivax TRAP protein | | 分子名称: | CHLORIDE ION, MAGNESIUM ION, Sporozoite surface protein 2, ... | | 著者 | Song, G, Koksal, A.C, Lu, C, Springer, T.A. | | 登録日 | 2012-10-25 | | 公開日 | 2012-12-26 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.241 Å) | | 主引用文献 | Shape change in the receptor for gliding motility in Plasmodium sporozoites.
Proc.Natl.Acad.Sci.USA, 109, 2012
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4HQK
 | | Crystal structure of Plasmodium falciparum TRAP, P4212 form | | 分子名称: | SULFATE ION, Thrombospondin-related anonymous protein, TRAP | | 著者 | Song, G, Koksal, A.C, Lu, C, Springer, T.A. | | 登録日 | 2012-10-25 | | 公開日 | 2012-12-26 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.249 Å) | | 主引用文献 | Shape change in the receptor for gliding motility in Plasmodium sporozoites.
Proc.Natl.Acad.Sci.USA, 109, 2012
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6RHV
 | | Crystal structure of mouse CD11b I-domain (CD11b-I) in complex with Staphylococcus aureus octameric bi-component leukocidin LukGH (LukH K319A mutant) | | 分子名称: | Beta-channel forming cytolysin, DIMETHYL SULFOXIDE, Integrin alpha-M, ... | | 著者 | Trstenjak, N, Milic, D, Djinovic-Carugo, K, Badarau, A. | | 登録日 | 2019-04-23 | | 公開日 | 2019-12-18 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | | 主引用文献 | Molecular mechanism of leukocidin GH-integrin CD11b/CD18 recognition and species specificity.
Proc.Natl.Acad.Sci.USA, 117, 2020
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1RTK
 | | Crystal Structure Analysis of the Bb segment of Factor B complexed with 4-guanidinobenzoic acid | | 分子名称: | 4-carbamimidamidobenzoic acid, Complement factor B Bb fragment, IODIDE ION, ... | | 著者 | Ponnuraj, K, Xu, Y, Macon, K, Moore, D, Volanakis, J.E, Narayana, S.V. | | 登録日 | 2003-12-10 | | 公開日 | 2004-12-14 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural analysis of engineered Bb fragment of complement factor B: insights into the activation mechanism of the alternative pathway C3-convertase.
Mol.Cell, 14, 2004
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1AUQ
 | | A1 DOMAIN OF VON WILLEBRAND FACTOR | | 分子名称: | A1 DOMAIN OF VON WILLEBRAND FACTOR, CADMIUM ION | | 著者 | Emsley, J, Cruz, M, Handin, R, Liddington, R. | | 登録日 | 1997-09-01 | | 公開日 | 1998-10-14 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal structure of the von Willebrand Factor A1 domain and implications for the binding of platelet glycoprotein Ib.
J.Biol.Chem., 273, 1998
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1M1U
 | | AN ISOLEUCINE-BASED ALLOSTERIC SWITCH CONTROLS AFFINITY AND SHAPE SHIFTING IN INTEGRIN CD11B A-DOMAIN | | 分子名称: | CALCIUM ION, Integrin alpha-M | | 著者 | Xiong, J.-P, Li, R, Essafi, M, Stehle, T, Arnaout, M.A. | | 登録日 | 2002-06-20 | | 公開日 | 2002-08-07 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | An isoleucine-based allosteric switch controls affinity and shape shifting in integrin CD11b A-domain.
J.Biol.Chem., 275, 2000
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3HI6
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2ODQ
 | | Complement component C2a, the catalytic fragment of C3- and C5-convertase of human complement | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Narayana, S.V.L, Krishnan, V. | | 登録日 | 2006-12-25 | | 公開日 | 2007-02-06 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | The crystal structure of c2a, the catalytic fragment of classical pathway c3 and c5 convertase of human complement.
J.Mol.Biol., 367, 2007
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2OK5
 | | Human Complement factor B | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Complement factor B, ... | | 著者 | Milder, F.J, Gomes, L, Schouten, A, Janssen, B.J.C, Huizinga, E.G, Romijn, R.A, Hemrika, W, Roos, A, Daha, M.R, Gros, P. | | 登録日 | 2007-01-16 | | 公開日 | 2007-02-27 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Factor B structure provides insights into activation of the central protease of the complement system.
Nat.Struct.Mol.Biol., 14, 2007
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1QCY
 | | THE CRYSTAL STRUCTURE OF THE I-DOMAIN OF HUMAN INTEGRIN ALPHA1BETA1 | | 分子名称: | I-DOMAIN OF INTEGRIN ALPHA1BETA1, MAGNESIUM ION | | 著者 | Kankare, J.A, Salminen, T.A, Nymalm, Y, Kaepylae, J, Heino, J, Johnson, M.S. | | 登録日 | 1999-05-12 | | 公開日 | 2003-09-02 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Jararhagin-derived RKKH Peptides Induce Structural Changes in a1I Domain of Human Integrin a1b1
J.Biol.Chem., 279, 2004
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