2QFG
 
 | | Solution Structure of the N-terminal SCR-1/5 fragment of Complement Factor H. | | 分子名称: | Complement factor H | | 著者 | Okemefuna, A.I, Gilbert, H.E, Griggs, K.M, Ormsby, R.J, Gordon, D.L, Perkins, S.J. | | 登録日 | 2007-06-27 | | 公開日 | 2007-09-25 | | 最終更新日 | 2024-02-21 | | 実験手法 | SOLUTION SCATTERING | | 主引用文献 | The regulatory SCR-1/5 and cell surface-binding SCR-16/20 fragments of factor H reveal partially folded-back solution structures and different self-associative properties.
J.Mol.Biol., 375, 2008
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2QFH
 | | Solution Structure of the C-terminal SCR-16/20 fragment of Complement Factor H. | | 分子名称: | Complement factor H | | 著者 | Okemefuna, A.I, Gilbert, H.E, Griggs, K.M, Ormsby, R.J, Gordon, D.L, Perkins, S.J. | | 登録日 | 2007-06-27 | | 公開日 | 2007-09-25 | | 最終更新日 | 2024-02-21 | | 実験手法 | SOLUTION SCATTERING | | 主引用文献 | The regulatory SCR-1/5 and cell surface-binding SCR-16/20 fragments of factor H reveal partially folded-back solution structures and different self-associative properties.
J.Mol.Biol., 375, 2008
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2EHF
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2IC4
 | | Solution structure of the His402 allotype of the Factor H SCR6-SCR7-SCR8 fragment | | 分子名称: | Complement factor H | | 著者 | Fernando, A.N, Furtado, P.B, Gilbert, H.E, Clark, S.J, Day, A.J, Sim, R.B, Perkins, S.J. | | 登録日 | 2006-09-12 | | 公開日 | 2007-04-10 | | 最終更新日 | 2024-02-21 | | 実験手法 | SOLUTION SCATTERING | | 主引用文献 | Associative and Structural Properties of the Region of Complement Factor H Encompassing the Tyr402His Disease-related Polymorphism and its Interactions with Heparin.
J.Mol.Biol., 368, 2007
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2JGX
 | | Structure of CCP module 7 of complement factor H - The AMD Not at risk varient (402Y) | | 分子名称: | COMPLEMENT FACTOR H | | 著者 | Herbert, A.P, Deakin, J.A, Schmidt, C.Q, Blaum, B.S, Egan, C, Ferreira, V.P, Pangburn, M.K, Lyon, M, Uhrin, D, Barlow, P.N. | | 登録日 | 2007-02-16 | | 公開日 | 2007-03-20 | | 最終更新日 | 2018-05-02 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure shows that a glycosaminoglycan and protein recognition site in factor H is perturbed by age-related macular degeneration-linked single nucleotide polymorphism.
J. Biol. Chem., 282, 2007
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2JGW
 | | Structure of CCP module 7 of complement factor H - The AMD at risk varient (402H) | | 分子名称: | COMPLEMENT FACTOR H | | 著者 | Herbert, A.P, Deakin, J.A, Schmidt, C.Q, Blaum, B.S, Egan, C, Ferreira, V.P, Pangburn, M.K, Lyon, M, Uhrin, D, Barlow, P.N. | | 登録日 | 2007-02-16 | | 公開日 | 2007-03-20 | | 最終更新日 | 2018-05-02 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure shows that a glycosaminoglycan and protein recognition site in factor H is perturbed by age-related macular degeneration-linked single nucleotide polymorphism.
J. Biol. Chem., 282, 2007
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2OK5
 | | Human Complement factor B | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Complement factor B, ... | | 著者 | Milder, F.J, Gomes, L, Schouten, A, Janssen, B.J.C, Huizinga, E.G, Romijn, R.A, Hemrika, W, Roos, A, Daha, M.R, Gros, P. | | 登録日 | 2007-01-16 | | 公開日 | 2007-02-27 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Factor B structure provides insights into activation of the central protease of the complement system.
Nat.Struct.Mol.Biol., 14, 2007
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2O39
 | | Human Adenovirus type 11 knob in complex with domains SCR1 and SCR2 of CD46 (membrane cofactor protein, MCP) | | 分子名称: | CALCIUM ION, Fiber protein, Membrane cofactor protein, ... | | 著者 | Persson, D.B, Reiter, D.M, Arnberg, N, Stehle, T. | | 登録日 | 2006-12-01 | | 公開日 | 2007-01-09 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | Adenovirus type 11 binding alters the conformation of its receptor CD46.
Nat.Struct.Mol.Biol., 14, 2007
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2GSX
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2G7I
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2BZM
 | | Solution structure of the primary host recognition region of complement factor H | | 分子名称: | COMPLEMENT FACTOR H | | 著者 | Herbert, A.P, Uhrin, D, Lyon, M, Pangburn, M.K, Barlow, P.N. | | 登録日 | 2005-08-18 | | 公開日 | 2006-03-22 | | 最終更新日 | 2011-07-13 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Disease-Associated Sequence Variations Congregate in a Polyanion Recognition Patch on Human Factor H Revealed in Three-Dimensional Structure.
J.Biol.Chem., 281, 2006
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2ERJ
 | | Crystal structure of the heterotrimeric interleukin-2 receptor in complex with interleukin-2 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Debler, E.W, Stauber, D.J, Wilson, I.A. | | 登録日 | 2005-10-25 | | 公開日 | 2006-02-21 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Crystal structure of the IL-2 signaling complex: Paradigm for a heterotrimeric cytokine receptor.
Proc.Natl.Acad.Sci.Usa, 103, 2006
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2ATY
 | | Complement receptor chimaeric conjugate CR2-Ig | | 分子名称: | Complement receptor chimeric conjugate CR2-Ig | | 著者 | Gilbert, H.E, Aslam, M, Guthridge, J.M, Holers, V.M, Perkins, S.J. | | 登録日 | 2005-08-26 | | 公開日 | 2006-01-31 | | 最終更新日 | 2024-02-14 | | 実験手法 | SOLUTION SCATTERING | | 主引用文献 | Extended Flexible Linker Structures in the Complement Chimaeric Conjugate CR2-Ig by Scattering, Analytical Ultracentrifugation and Constrained Modelling: Implications for Function and Therapy.
J.Mol.Biol., 356, 2006
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2C8I
 | | Complex Of Echovirus Type 12 With Domains 1, 2, 3 and 4 Of Its Receptor Decay Accelerating Factor (Cd55) By Cryo Electron Microscopy At 16 A | | 分子名称: | COMPLEMENT DECAY-ACCELERATING FACTOR, ECHOVIRUS 11 COAT PROTEIN VP1, ECHOVIRUS 11 COAT PROTEIN VP2, ... | | 著者 | Pettigrew, D.M, Williams, D.T, Kerrigan, D, Evans, D.J, Lea, S.M, Bhella, D. | | 登録日 | 2005-12-05 | | 公開日 | 2006-01-17 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (14 Å) | | 主引用文献 | Structural and Functional Insights Into the Interaction of Echoviruses and Decay-Accelerating Factor.
J.Biol.Chem., 281, 2006
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2A55
 | | Solution structure of the two N-terminal CCP modules of C4b-binding protein (C4BP) alpha-chain. | | 分子名称: | C4b-binding protein | | 著者 | Jenkins, H.T, Mark, L, Ball, G, Lindahl, G, Uhrin, D, Blom, A.M, Barlow, P.N. | | 登録日 | 2005-06-30 | | 公開日 | 2005-12-13 | | 最終更新日 | 2022-03-09 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Human C4b-binding Protein, Structural Basis for Interaction with Streptococcal M Protein, a Major Bacterial Virulence Factor
J.Biol.Chem., 281, 2006
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2B5I
 | | cytokine receptor complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cytokine receptor common gamma chain, ... | | 著者 | Wang, X, Rickert, M, Garcia, K.C. | | 登録日 | 2005-09-28 | | 公開日 | 2005-11-29 | | 最終更新日 | 2021-10-20 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structure of the quaternary complex of interleukin-2 with its alpha, beta, and gammac receptors.
Science, 310, 2005
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1W2S
 | | Solution structure of CR2 SCR 1-2 in its complex with C3d by X-ray scattering | | 分子名称: | COMPLEMENT C3 PRECURSOR, COMPLEMENT RECEPTOR TYPE 2 PRECURSOR, | | 著者 | Gilbert, H.E, Hannan, J.P, Holers, V.M, Perkins, S.J. | | 登録日 | 2004-07-08 | | 公開日 | 2005-09-29 | | 最終更新日 | 2024-05-08 | | 実験手法 | SOLUTION SCATTERING | | 主引用文献 | Solution Structure of the Complex between Cr2 Scr 1-2 and C3D of Human Complement: An X-Ray Scattering and Sedimentation Modelling Study.
J.Mol.Biol., 346, 2005
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1W2R
 | | Solution structure of CR2 SCR 1-2 by X-ray scattering | | 分子名称: | COMPLEMENT RECEPTOR TYPE 2 PRECURSOR, | | 著者 | Gilbert, H.E, Hannan, J.P, Holers, V.M, Perkins, S.J. | | 登録日 | 2004-07-08 | | 公開日 | 2005-09-29 | | 最終更新日 | 2024-05-08 | | 実験手法 | SOLUTION SCATTERING | | 主引用文献 | Solution Structure of the Complex between Cr2 Scr 1-2 and C3D of Human Complement: An X-Ray Scattering and Sedimentation Modelling Study.
J.Mol.Biol., 346, 2005
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1ZJK
 | | Crystal structure of the zymogen catalytic region of human MASP-2 | | 分子名称: | Mannan-binding lectin serine protease 2 | | 著者 | Gal, P, Harmat, V, Kocsis, A, Bian, T, Barna, L, Ambrus, G, Vegh, B, Balczer, J, Sim, R.B, Naray-Szabo, G, Zavodszky, P. | | 登録日 | 2005-04-29 | | 公開日 | 2005-07-26 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.18 Å) | | 主引用文献 | A True Autoactivating Enzyme: Structural insight into mannose-binding lectin-associated serine protease-2 activations
J.Biol.Chem., 280, 2005
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1Z92
 | | structure of interleukin-2 with its alpha receptor | | 分子名称: | Interleukin-2, Interleukin-2 receptor alpha chain | | 著者 | Rickert, M, Wang, X.Q, Goriatcheva, N, Boulanger, M.J, Garcia, K.C. | | 登録日 | 2005-03-31 | | 公開日 | 2005-06-07 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | The structure of interleukin-2 complexed with its alpha receptor.
Science, 308, 2005
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1SS2
 | | Solution structure of the second complement control protein (CCP) module of the GABA(B)R1a receptor, Pro-119 cis conformer | | 分子名称: | Gamma-aminobutyric acid type B receptor, subunit 1 | | 著者 | Blein, S, Uhrin, D, Smith, B.O, White, J.H, Barlow, P.N. | | 登録日 | 2004-03-23 | | 公開日 | 2004-10-12 | | 最終更新日 | 2022-03-02 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural analysis of the complement control protein (CCP) modules of GABA(B) receptor 1a: only one of the two CCP modules is compactly folded.
J.Biol.Chem., 279, 2004
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1SRZ
 | | Solution structure of the second complement control protein (CCP) module of the GABA(B)R1a receptor, Pro-119 trans conformer | | 分子名称: | Gamma-aminobutyric acid type B receptor, subunit 1 | | 著者 | Blein, S, Uhrin, D, Smith, B.O, White, J.H, Barlow, P.N. | | 登録日 | 2004-03-23 | | 公開日 | 2004-10-12 | | 最終更新日 | 2022-03-02 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural Analysis of the Complement Control Protein (CCP) Modules of GABAB Receptor 1a: ONLY ONE OF THE TWO CCP MODULES IS COMPACTLY FOLDED
J.Biol.Chem., 279, 2004
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1Q3X
 | | Crystal structure of the catalytic region of human MASP-2 | | 分子名称: | GLYCEROL, Mannan-binding lectin serine protease 2, SODIUM ION | | 著者 | Harmat, V, Gal, P, Kardos, J, Szilagyi, K, Ambrus, G, Naray-Szabo, G, Zavodszky, P. | | 登録日 | 2003-08-01 | | 公開日 | 2004-08-03 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.23 Å) | | 主引用文献 | The structure of MBL-associated serine protease-2 reveals that identical substrate specificities of C1s and MASP-2 are realized through different sets of enzyme-substrate interactions
J.Mol.Biol., 342, 2004
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1PPQ
 | | NMR structure of 16th module of Immune Adherence Receptor, Cr1 (Cd35) | | 分子名称: | Complement receptor type 1 | | 著者 | O'Leary, J.M, Bromek, K, Black, G.M, Uhrinova, S, Schmitz, C, Krych, M, Atkinson, J.P, Uhrin, D, Barlow, P.N. | | 登録日 | 2003-06-17 | | 公開日 | 2004-05-04 | | 最終更新日 | 2021-10-27 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Backbone dynamics of complement control protein (CCP) modules reveals mobility in binding surfaces.
Protein Sci., 13, 2004
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1NTJ
 | | Model of rat Crry determined by solution scattering, curve fitting and homology modelling | | 分子名称: | complement receptor related protein | | 著者 | Aslam, M, Guthridge, J.M, Hack, B.K, Quigg, R.J, Holers, V.M, Perkins, S.J. | | 登録日 | 2003-01-30 | | 公開日 | 2004-02-03 | | 最終更新日 | 2024-02-14 | | 実験手法 | SOLUTION SCATTERING (30 Å) | | 主引用文献 | The Extended Multidomain Solution Structures of the Complement Protein
Crry and its Chimeric Conjugate Crry-Ig by Scattering, Analytical
Ultracentrifugation and Constrained Modelling: Implications for Function and
Therapy
J.Mol.Biol., 329, 2003
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