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4ZOW
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Crystal structure of E. coli multidrug transporter MdfA in complex with chloramphenicol
分子名称: CHLORAMPHENICOL, Multidrug transporter MdfA
著者Zhang, X.C, Heng, J, Zhao, Y, Wang, X.
登録日2015-05-07
公開日2015-08-19
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Substrate-bound structure of the E. coli multidrug resistance transporter MdfA
Cell Res., 25, 2015
4ZP2
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BU of 4zp2 by Molmil
Crystal structure of E. coli multidrug transporter MdfA in complex with n-dodecyl-N,N-dimethylamine-N-oxide
分子名称: LAURYL DIMETHYLAMINE-N-OXIDE, Multidrug transporter MdfA
著者Zhang, X.C, Heng, J, Zhao, Y, Wang, X.
登録日2015-05-07
公開日2015-08-19
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Substrate-bound structure of the E. coli multidrug resistance transporter MdfA
Cell Res., 25, 2015
4ZWB
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BU of 4zwb by Molmil
Crystal structure of maltose-bound human GLUT3 in the outward-occluded conformation at 2.4 angstrom
分子名称: Solute carrier family 2, facilitated glucose transporter member 3, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
著者Deng, D, Sun, P.C, Yan, C.Y, Yan, N.
登録日2015-05-19
公開日2015-07-22
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Molecular basis of ligand recognition and transport by glucose transporters
Nature, 526, 2015
4ZWC
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BU of 4zwc by Molmil
Crystal structure of maltose-bound human GLUT3 in the outward-open conformation at 2.6 angstrom
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Solute carrier family 2, facilitated glucose transporter member 3, ...
著者Deng, D, Sun, P.C, Yan, C.Y, Yan, N.
登録日2015-05-19
公開日2015-07-22
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Molecular basis of ligand recognition and transport by glucose transporters
Nature, 526, 2015
4ZW9
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BU of 4zw9 by Molmil
Crystal structure of human GLUT3 bound to D-glucose in the outward-occluded conformation at 1.5 angstrom
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Solute carrier family 2, facilitated glucose transporter member 3, ...
著者Deng, D, Sun, P.C, Yan, C.Y, Yan, N.
登録日2015-05-19
公開日2015-07-22
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.502 Å)
主引用文献Molecular basis of ligand recognition and transport by glucose transporters
Nature, 526, 2015
8ET8
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BU of 8et8 by Molmil
Cryo-EM structure of the organic cation transporter 1 in complex with verapamil
分子名称: (2S)-2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, OCT1
著者Suo, Y, Wright, N.J, Lee, S.-Y.
登録日2022-10-16
公開日2023-05-31
最終更新日2023-08-02
実験手法ELECTRON MICROSCOPY (3.45 Å)
主引用文献Molecular basis of polyspecific drug and xenobiotic recognition by OCT1 and OCT2.
Nat.Struct.Mol.Biol., 30, 2023
8EX7
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BU of 8ex7 by Molmil
Human S1P transporter Spns2 in an outward-facing partially occluded conformation (state 3)
分子名称: Sphingosine-1-phosphate transporter SPNS2
著者Ahmed, S, Zhao, H, Dai, Y, Lee, C.H.
登録日2022-10-24
公開日2023-05-31
最終更新日2023-06-28
実験手法ELECTRON MICROSCOPY (3.53 Å)
主引用文献Structural and functional insights into Spns2-mediated transport of sphingosine-1-phosphate.
Cell, 186, 2023
8ET9
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BU of 8et9 by Molmil
Cryo-EM structure of the organic cation transporter 2 in complex with 1-methyl-4-phenylpyridinium
分子名称: 1-methyl-4-phenylpyridin-1-ium, OCT2
著者Suo, Y, Wright, N.J, Lee, S.-Y.
登録日2022-10-16
公開日2023-05-31
最終更新日2023-08-02
実験手法ELECTRON MICROSCOPY (3.61 Å)
主引用文献Molecular basis of polyspecific drug and xenobiotic recognition by OCT1 and OCT2.
Nat.Struct.Mol.Biol., 30, 2023
8ET7
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Cryo-EM structure of the organic cation transporter 1 in complex with diphenhydramine
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, N-[2-(BENZHYDRYLOXY)ETHYL]-N,N-DIMETHYLAMINE, OCT1
著者Suo, Y, Wright, N.J, Lee, S.-Y.
登録日2022-10-16
公開日2023-05-31
最終更新日2023-08-02
実験手法ELECTRON MICROSCOPY (3.77 Å)
主引用文献Molecular basis of polyspecific drug and xenobiotic recognition by OCT1 and OCT2.
Nat.Struct.Mol.Biol., 30, 2023
8EX4
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BU of 8ex4 by Molmil
Human S1P transporter Spns2 in an inward-facing open conformation (state 1)
分子名称: (2S,3R,4E)-2-amino-3-hydroxyoctadec-4-en-1-yl dihydrogen phosphate, Sphingosine-1-phosphate transporter SPNS2
著者Ahmed, S, Zhao, H, Dai, Y, Lee, C.H.
登録日2022-10-24
公開日2023-05-31
最終更新日2023-06-28
実験手法ELECTRON MICROSCOPY (2.93 Å)
主引用文献Structural and functional insights into Spns2-mediated transport of sphingosine-1-phosphate.
Cell, 186, 2023
8EX5
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Human S1P transporter Spns2 in an outward-facing open conformation (state 4)
分子名称: Sphingosine-1-phosphate transporter SPNS2
著者Ahmed, S, Zhao, H, Dai, Y, Lee, C.H.
登録日2022-10-24
公開日2023-05-31
最終更新日2023-06-28
実験手法ELECTRON MICROSCOPY (3.47 Å)
主引用文献Structural and functional insights into Spns2-mediated transport of sphingosine-1-phosphate.
Cell, 186, 2023
8ET6
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BU of 8et6 by Molmil
Cryo-EM structure of the organic cation transporter 1 in the apo state
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, OCT1
著者Suo, Y, Wright, N.J, Lee, S.-Y.
登録日2022-10-16
公開日2023-05-31
最終更新日2023-08-02
実験手法ELECTRON MICROSCOPY (3.57 Å)
主引用文献Molecular basis of polyspecific drug and xenobiotic recognition by OCT1 and OCT2.
Nat.Struct.Mol.Biol., 30, 2023
8EX6
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BU of 8ex6 by Molmil
Human S1P transporter Spns2 in an inward-facing open conformation (state 1*)
分子名称: (2S,3R,4E)-2-amino-3-hydroxyoctadec-4-en-1-yl dihydrogen phosphate, Sphingosine-1-phosphate transporter SPNS2
著者Ahmed, S, Zhao, H, Dai, Y, Lee, C.H.
登録日2022-10-24
公開日2023-05-31
最終更新日2023-06-28
実験手法ELECTRON MICROSCOPY (3.54 Å)
主引用文献Structural and functional insights into Spns2-mediated transport of sphingosine-1-phosphate.
Cell, 186, 2023
8EX8
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BU of 8ex8 by Molmil
Human S1P transporter Spns2 in an outward-facing partially occluded conformation (state 2)
分子名称: Sphingosine-1-phosphate transporter SPNS2
著者Ahmed, S, Zhao, H, Dai, Y, Lee, C.H.
登録日2022-10-24
公開日2023-05-31
最終更新日2023-06-28
実験手法ELECTRON MICROSCOPY (4.17 Å)
主引用文献Structural and functional insights into Spns2-mediated transport of sphingosine-1-phosphate.
Cell, 186, 2023
7ZH0
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BU of 7zh0 by Molmil
Structure of human OCT3 in lipid nanodisc
分子名称: Solute carrier family 22 member 3
著者Khanppnavar, B, Korkhov, V, Qi, C.
登録日2022-04-05
公開日2022-11-09
最終更新日2023-04-19
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural basis of organic cation transporter-3 inhibition.
Nat Commun, 13, 2022
7ZH6
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BU of 7zh6 by Molmil
Structure of human OCT3 in complex with inhibitor Corticosterone
分子名称: CORTICOSTERONE, Solute carrier family 22 member 3
著者Khanppnavar, B, Korkhov, V.
登録日2022-04-05
公開日2022-11-09
最終更新日2023-04-19
実験手法ELECTRON MICROSCOPY (3.67 Å)
主引用文献Structural basis of organic cation transporter-3 inhibition.
Nat Commun, 13, 2022
7ZHA
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BU of 7zha by Molmil
Structure of human OCT3 in complex with inhibitor decynium-22
分子名称: 1-ethyl-2-[(1-ethylquinolin-2-yl)methyl]quinoline, Solute carrier family 22 member 3
著者Khanppnavar, B, Korkhov, V.
登録日2022-04-05
公開日2022-11-09
最終更新日2023-04-19
実験手法ELECTRON MICROSCOPY (3.55 Å)
主引用文献Structural basis of organic cation transporter-3 inhibition.
Nat Commun, 13, 2022
7YUF
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BU of 7yuf by Molmil
apo human SPNS2
分子名称: NbFab H-chain, NbFab L-chain, Sphingosine-1-phosphate transporter SPNS2, ...
著者He, Y, Duan, Y.
登録日2022-08-17
公開日2023-09-06
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (3.29 Å)
主引用文献Structural basis of Sphingosine-1-phosphate transport via human SPNS2.
Cell Res., 34, 2024
7YUD
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BU of 7yud by Molmil
FTY720p-bound human SPNS2
分子名称: (2~{S})-2-azanyl-4-(4-octylphenyl)-2-[[oxidanyl-bis(oxidanylidene)-$l^{6}-phosphanyl]oxymethyl]butan-1-ol, NbFab L-chain, NbFab-H-chain, ...
著者He, Y, Duan, Y.
登録日2022-08-17
公開日2023-09-06
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (2.98 Å)
主引用文献Structural basis of Sphingosine-1-phosphate transport via human SPNS2.
Cell Res., 34, 2024
7YUB
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BU of 7yub by Molmil
S1P-bound human SPNS2
分子名称: (2S,3R,4E)-2-amino-3-hydroxyoctadec-4-en-1-yl dihydrogen phosphate, NbFab-H-chain, NbFab-L-chain, ...
著者He, Y, Duan, Y.
登録日2022-08-17
公開日2023-09-06
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (3.22 Å)
主引用文献Structural basis of Sphingosine-1-phosphate transport via human SPNS2.
Cell Res., 34, 2024
8BVS
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BU of 8bvs by Molmil
Cryo-EM structure of rat SLC22A6 bound to tenofovir
分子名称: CHLORIDE ION, Solute carrier family 22 member 6, Synthetic nanobody (Sybody), ...
著者Parker, J.L, Kato, T, Newstead, S.
登録日2022-12-05
公開日2023-07-19
最終更新日2023-11-22
実験手法ELECTRON MICROSCOPY (3.61 Å)
主引用文献Molecular basis for selective uptake and elimination of organic anions in the kidney by OAT1.
Nat.Struct.Mol.Biol., 30, 2023
8BVT
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BU of 8bvt by Molmil
Cryo-EM structure of rat SLC22A6 bound to probenecid
分子名称: 4-(dipropylsulfamoyl)benzoic acid, Solute carrier family 22 member 6, Synthetic nanobody (Sybody)
著者Parker, J.L, Kato, T, Newstead, S.
登録日2022-12-06
公開日2023-07-19
最終更新日2023-11-22
実験手法ELECTRON MICROSCOPY (3.94 Å)
主引用文献Molecular basis for selective uptake and elimination of organic anions in the kidney by OAT1.
Nat.Struct.Mol.Biol., 30, 2023
8BW7
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BU of 8bw7 by Molmil
Cryo-EM structure of rat SLC22A6 bound to alpha-ketoglutaric acid
分子名称: 2-OXOGLUTARIC ACID, CHLORIDE ION, Solute carrier family 22 member 6, ...
著者Parker, J.L, Kato, T, Newstead, S.
登録日2022-12-06
公開日2023-07-19
最終更新日2023-11-22
実験手法ELECTRON MICROSCOPY (3.53 Å)
主引用文献Molecular basis for selective uptake and elimination of organic anions in the kidney by OAT1.
Nat.Struct.Mol.Biol., 30, 2023
8BVR
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BU of 8bvr by Molmil
Cryo-EM structure of rat SLC22A6 in the apo state
分子名称: PHOSPHATE ION, Solute carrier family 22 member 6, Synthetic nanobody (Sybody)
著者Parker, J.L, Kato, T, Newstead, S.
登録日2022-12-05
公開日2023-07-19
最終更新日2023-11-22
実験手法ELECTRON MICROSCOPY (3.52 Å)
主引用文献Molecular basis for selective uptake and elimination of organic anions in the kidney by OAT1.
Nat.Struct.Mol.Biol., 30, 2023
8JTA
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BU of 8jta by Molmil
Human VMAT2 complex with tetrabenazine
分子名称: Synaptic vesicular amine transporter, tetrabenazine
著者Jiang, D.H, Wu, D.
登録日2023-06-21
公開日2023-11-29
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (3.36 Å)
主引用文献Transport and inhibition mechanisms of human VMAT2.
Nature, 626, 2024

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件を2024-05-22に公開中

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