8EX6

Human S1P transporter Spns2 in an inward-facing open conformation (state 1*)

Summary for 8EX6

• Entry DOI: 10.2210/pdb8ex6/pdb
• EMDB information: 28652
• Descriptor: Sphingosine-1-phosphate transporter SPNS2, (2S,3R,4E)-2-amino-3-hydroxyoctadec-4-en-1-yl dihydrogen phosphate (2 entities in total)
• Functional Keywords: transporter, membrane protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 49275.66

Authors

Ahmed, S.,Zhao, H.,Dai, Y.,Lee, C.H. (deposition date: 2022-10-24, release date: 2023-05-31, Last modification date: 2023-06-28)

• Primary citation: Chen, H.,Ahmed, S.,Zhao, H.,Elghobashi-Meinhardt, N.,Dai, Y.,Kim, J.H.,McDonald, J.G.,Li, X.,Lee, C.H.; Structural and functional insights into Spns2-mediated transport of sphingosine-1-phosphate.; Cell, 186:2644-, 2023; PubMed: 37224812; DOI: 10.1016/j.cell.2023.04.028

Experimental method

ELECTRON MICROSCOPY (3.54 Å)