PDB: 113 件ウェブページステータス検索Chemie searchBIRD

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8FVZ	PiPT Y150A 分子名称: CITRATE ANION, PHOSPHATE ION, Phosphate transporter 著者 Gupta, M, Finer-Moore, J, Stroud, R.M. 登録日 2023-01-20 公開日 2024-01-03 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Roles of PiPT residues in phosphate binding and transport tested by mutagenesis To be published
8G92	Structure of inhibitor 16d-bound SPNS2 分子名称: 3-[3-(4-decylphenyl)-1,2,4-oxadiazol-5-yl]propan-1-amine, Sphingosine-1-phosphate transporter SPNS2 著者 Chen, H, Li, X. 登録日 2023-02-21 公開日 2023-05-24 最終更新日 2023-12-13 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Structural and functional insights into Spns2-mediated transport of sphingosine-1-phosphate. Cell, 186, 2023
6GV1	Crystal structure of E.coli Multidrug/H+ antiporter MdfA in outward open conformation with bound Fab fragment 分子名称: Fab fragment YN1074 heavy chain, Fab fragment YN1074 light chain, Major Facilitator Superfamily multidrug/H+ antiporter MdfA from E.coli, ... 著者 Nagarathinam, K, Parthier, C, Stubbs, M.T, Tanabe, M. 登録日 2018-06-20 公開日 2018-10-03 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 Outward open conformation of a Major Facilitator Superfamily multidrug/H+antiporter provides insights into switching mechanism. Nat Commun, 9, 2018
6H7D	Crystal Structure of A. thaliana Sugar Transport Protein 10 in complex with glucose in the outward occluded state 分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, PHOSPHATE ION, ... 著者 Pedersen, B.P, Paulsen, P.A, Custodio, T.F. 登録日 2018-07-31 公開日 2019-02-06 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal structure of the plant symporter STP10 illuminates sugar uptake mechanism in monosaccharide transporter superfamily. Nat Commun, 10, 2019
7AAQ	sugar/H+ symporter STP10 in outward occluded conformation 分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 3,6,9,12,15,18,21,24,27-NONAOXANONACOSANE-1,29-DIOL, ACETATE ION, ... 著者 Bavnhoej, L, Paulsen, P.A, Pedersen, B.P. 登録日 2020-09-04 公開日 2021-08-18 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.81 Å) 主引用文献 Molecular mechanism of sugar transport in plants unveiled by structures of glucose/H + symporter STP10. Nat.Plants, 7, 2021
7AAR	sugar/H+ symporter STP10 in inward open conformation 分子名称: CHLORIDE ION, Octyl Glucose Neopentyl Glycol, Sugar transport protein 10, ... 著者 Bavnhoej, L, Paulsen, P.A, Pedersen, B.P. 登録日 2020-09-04 公開日 2021-08-18 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.64 Å) 主引用文献 Molecular mechanism of sugar transport in plants unveiled by structures of glucose/H + symporter STP10. Nat.Plants, 7, 2021
4PYP	Crystal structure of the human glucose transporter GLUT1 分子名称: Solute carrier family 2, facilitated glucose transporter member 1, nonyl beta-D-glucopyranoside 著者 Deng, D, Yan, C.Y, Xu, C, Wu, J.P, Sun, P.C, Hu, M.X, Yan, N. 登録日 2014-03-27 公開日 2014-05-21 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (3.166 Å) 主引用文献 Crystal structure of the human glucose transporter GLUT1 Nature, 510, 2014
4QIQ	Crystal structure of D-xylose-proton symporter 分子名称: D-xylose-proton symporter, ZINC ION 著者 Wisedchaisri, G, Park, M, Iadanza, M.G, Zheng, H, Gonen, T. 登録日 2014-06-01 公開日 2014-08-06 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.51 Å) 主引用文献 Proton-coupled sugar transport in the prototypical major facilitator superfamily protein XylE. Nat Commun, 5, 2014
7WSM	Cryo-EM structure of human glucose transporter GLUT4 bound to cytochalasin B in lipid nanodiscs 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cytochalasin B, Solute carrier family 2, ... 著者 Yuan, Y, Kong, F, Xu, H, Zhu, A, Yan, N, Yan, C. 登録日 2022-01-30 公開日 2022-05-18 最終更新日 2022-05-25 実験手法 ELECTRON MICROSCOPY (3.25 Å) 主引用文献 Cryo-EM structure of human glucose transporter GLUT4. Nat Commun, 13, 2022
7WSN	Cryo-EM structure of human glucose transporter GLUT4 bound to cytochalasin B in detergent micelles 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cytochalasin B, Solute carrier family 2, ... 著者 Yuan, Y, Kong, F, Xu, H, Zhu, A, Yan, N, Yan, C. 登録日 2022-01-30 公開日 2022-05-18 最終更新日 2022-05-25 実験手法 ELECTRON MICROSCOPY (3.31 Å) 主引用文献 Cryo-EM structure of human glucose transporter GLUT4. Nat Commun, 13, 2022
3O7P	Crystal structure of the E.coli Fucose:proton symporter, FucP (N162A) 分子名称: L-fucose-proton symporter, nonyl beta-D-glucopyranoside 著者 Dang, S.Y, Sun, L.F, Wang, J, Yan, N. 登録日 2010-07-30 公開日 2010-09-15 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (3.196 Å) 主引用文献 Structure of a fucose transporter in an outward-open conformation Nature, 467, 2010
3O7Q	Crystal structure of a Major Facilitator Superfamily (MFS) transporter, FucP, in the outward conformation 分子名称: L-fucose-proton symporter, nonyl beta-D-glucopyranoside 著者 Sun, L.F, Dang, S.Y, Wang, J, Yan, N. 登録日 2010-07-30 公開日 2010-09-15 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (3.143 Å) 主引用文献 Structure of a fucose transporter in an outward-open conformation Nature, 467, 2010
8XOB	VMAT2 protonated state 分子名称: Synaptic vesicular amine transporter,transporter B 著者 Jiang, D.H, Wu, D. 登録日 2023-12-31 公開日 2024-05-08 実験手法 ELECTRON MICROSCOPY (3.15 Å) 主引用文献 VMAT2 protonated state To Be Published
8XO9	VMAT2 complex with noradrenaline in cytosol-facing state 分子名称: Noradrenaline, Synaptic vesicular amine transporter,transporter A 著者 Jiang, D.H, Wu, D. 登録日 2023-12-31 公開日 2024-05-08 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 VMAT2 complex with noradrenaline in cytosol-facing state To Be Published
6OOQ	protein C 分子名称: (3ALPHA,5BETA,12ALPHA)-3,12-DIHYDROXYCHOLAN-24-OIC ACID, Multidrug transporter MdfA 著者 Lu, M. 登録日 2019-04-23 公開日 2019-09-04 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structure of an engineered multidrug transporter MdfA reveals the molecular basis for substrate recognition. Commun Biol, 2, 2019
8XOA	VMAT2 complex with MPP+ 分子名称: 1-methyl-4-phenylpyridin-1-ium, Synaptic vesicular amine transporter,Synaptic vesicular amine transporter,transporterA 著者 Jiang, D.H, Wu, D. 登録日 2023-12-31 公開日 2024-05-08 実験手法 ELECTRON MICROSCOPY (3.03 Å) 主引用文献 VMAT2 complex with MPP+ To Be Published
6OOP	protein B 分子名称: 1,1'-dimethyl-4,4'-bipyridin-1-ium, Multidrug transporter MdfA, PRASEODYMIUM ION 著者 Lu, M. 登録日 2019-04-23 公開日 2019-09-04 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structure of an engineered multidrug transporter MdfA reveals the molecular basis for substrate recognition. Commun Biol, 2, 2019
6OOM	PROTEIN A 分子名称: LAURYL DIMETHYLAMINE-N-OXIDE, Multidrug transporter MdfA, PRASEODYMIUM ION 著者 Lu, M. 登録日 2019-04-23 公開日 2019-09-04 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structure of an engineered multidrug transporter MdfA reveals the molecular basis for substrate recognition. Commun Biol, 2, 2019
6RW3	The molecular basis for sugar import in malaria parasites. 分子名称: Hexose transporter 1, alpha-D-glucopyranose, beta-D-glucopyranose 著者 Qureshi, A, Matsuoka, R, Brock, J, Drew, D. 登録日 2019-06-03 公開日 2020-01-29 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (3.65 Å) 主引用文献 The molecular basis for sugar import in malaria parasites. Nature, 578, 2020
6S4M	Crystal structure of the human organic anion transporter MFSD10 (TETRAN) 分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, CITRIC ACID, Major facilitator superfamily domain-containing protein 10 著者 Pascoa, T.C, Pike, A.C.W, Bushell, S.R, Quigley, A, Chu, A, Mukhopadhyay, S.M.M, Shrestha, L, Venkaya, S, Chalk, R, Burgess-Brown, N.A, Edwards, A.M, Arrowsmith, C.H, Bountra, C, Carpenter, E.P, Structural Genomics Consortium (SGC) 登録日 2019-06-28 公開日 2020-05-13 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal structure of the human organic anion transporter TETRAN (MFSD10) To be published
7CRZ	Crystal structure of human glucose transporter GLUT3 bound with C3361 分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S,3R,4S,5R,6R)-6-(hydroxymethyl)-4-undec-10-enoxy-oxane-2,3,5-triol, Solute carrier family 2, ... 著者 Yuan, Y.Y, Zhang, S, Wang, N, Jiang, X, Yan, N. 登録日 2020-08-14 公開日 2021-01-13 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Orthosteric-allosteric dual inhibitors of PfHT1 as selective antimalarial agents. Proc.Natl.Acad.Sci.USA, 118, 2021
4JA3	Partially occluded inward open conformation of the xylose transporter XylE from E. coli 分子名称: CADMIUM ION, D-xylose-proton symporter, LUTETIUM (III) ION 著者 Quistgaard, E.M, Low, C, Moberg, P, Tresaugues, L, Nordlund, P. 登録日 2013-02-18 公開日 2013-05-01 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3.8 Å) 主引用文献 Structural basis for substrate transport in the GLUT-homology family of monosaccharide transporters. Nat.Struct.Mol.Biol., 20, 2013
4JA4	Inward open conformation of the xylose transporter XylE from E. coli 分子名称: CADMIUM ION, D-xylose-proton symporter 著者 Quistgaard, E.M, Low, C, Moberg, P, Tresaugues, L, Nordlund, P. 登録日 2013-02-18 公開日 2013-05-01 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (4.2 Å) 主引用文献 Structural basis for substrate transport in the GLUT-homology family of monosaccharide transporters. Nat.Struct.Mol.Biol., 20, 2013
6M2L	Crystal structure of Plasmodium falciparum hexose transporter PfHT1 bound with C3361 分子名称: (2S,3R,4S,5R,6R)-6-(hydroxymethyl)-4-undec-10-enoxy-oxane-2,3,5-triol, Hexose transporter 1 著者 Jiang, X, Yuan, Y.Y, Zhang, S, Wang, N, Yan, C.Y, Yan, N. 登録日 2020-02-27 公開日 2020-09-09 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (3.7 Å) 主引用文献 Structural Basis for Blocking Sugar Uptake into the Malaria Parasite Plasmodium falciparum. Cell, 183, 2020
7D5Q	Structure of NorC transporter (K398A mutant) in an outward-open conformation in complex with a single-chain Indian camelid antibody 分子名称: Drug transporter, putative, ICab, ... 著者 Kumar, S, Athreya, A, Penmatsa, A. 登録日 2020-09-27 公開日 2021-06-09 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (3.6 Å) 主引用文献 Structural basis of inhibition of a transporter from Staphylococcus aureus, NorC, through a single-domain camelid antibody. Commun Biol, 4, 2021

 

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