7WSM

Cryo-EM structure of human glucose transporter GLUT4 bound to cytochalasin B in lipid nanodiscs

Summary for 7WSM

• Entry DOI: 10.2210/pdb7wsm/pdb
• EMDB information: 32760
• Descriptor: Solute carrier family 2, facilitated glucose transporter member 4, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cytochalasin B (3 entities in total)
• Functional Keywords: glucose transporter, glut4, diabetes, cytochalasin b, transport protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 57012.21

Authors

Yuan, Y.,Kong, F.,Xu, H.,Zhu, A.,Yan, N.,Yan, C. (deposition date: 2022-01-30, release date: 2022-05-18, Last modification date: 2022-05-25)

• Primary citation: Yuan, Y.,Kong, F.,Xu, H.,Zhu, A.,Yan, N.,Yan, C.; Cryo-EM structure of human glucose transporter GLUT4.; Nat Commun, 13:2671-2671, 2022; PubMed: 35562357; DOI: 10.1038/s41467-022-30235-5

Experimental method

ELECTRON MICROSCOPY (3.25 Å)