7WSM
Cryo-EM structure of human glucose transporter GLUT4 bound to cytochalasin B in lipid nanodiscs
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Solute carrier family 2, facilitated glucose transporter member 4 | polymer | 520 | 56108.2 | 1 | UniProt (P14672) Pfam (PF00083) | Homo sapiens (human) | Glucose transporter type 4,insulin-responsive,GLUT-4 |
| 2 | B (B) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 3 | C (A) | Cytochalasin B | non-polymer | 479.6 | 1 | Chemie (5RH) |
Sequence modifications
A: 1 - 509 (UniProt: P14672)
| PDB | External Database | Details |
|---|---|---|
| Met -10 | - | initiating methionine |
| Asp -9 | - | expression tag |
| Tyr -8 | - | expression tag |
| Lys -7 | - | expression tag |
| Asp -6 | - | expression tag |
| Asp -5 | - | expression tag |
| Asp -4 | - | expression tag |
| Asp -3 | - | expression tag |
| Lys -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Thr 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 56108.2 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 424.4 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 479.6 | |
| All* | Total formula weight | 57012.2 |
