8G92
Structure of inhibitor 16d-bound SPNS2
Summary for 8G92
Entry DOI | 10.2210/pdb8g92/pdb |
EMDB information | 29860 |
Descriptor | Sphingosine-1-phosphate transporter SPNS2, 3-[3-(4-decylphenyl)-1,2,4-oxadiazol-5-yl]propan-1-amine (2 entities in total) |
Functional Keywords | spns2, sphingosine-1-phosphate, major facilitator superfamily, transporter, immune system |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 50113.65 |
Authors | |
Primary citation | Chen, H.,Ahmed, S.,Zhao, H.,Elghobashi-Meinhardt, N.,Dai, Y.,Kim, J.H.,McDonald, J.G.,Li, X.,Lee, C.H. Structural and functional insights into Spns2-mediated transport of sphingosine-1-phosphate. Cell, 186:2644-2655.e16, 2023 Cited by PubMed: 37224812DOI: 10.1016/j.cell.2023.04.028 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.6 Å) |
Structure validation
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