8G92

Structure of inhibitor 16d-bound SPNS2

Summary for 8G92

Entry DOI	10.2210/pdb8g92/pdb
EMDB information	29860
Descriptor	Sphingosine-1-phosphate transporter SPNS2, 3-[3-(4-decylphenyl)-1,2,4-oxadiazol-5-yl]propan-1-amine (2 entities in total)
Functional Keywords	spns2, sphingosine-1-phosphate, major facilitator superfamily, transporter, immune system
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	50113.65
Authors	Chen, H.,Li, X. (deposition date: 2023-02-21, release date: 2023-05-24, Last modification date: 2023-12-13)
Primary citation	Chen, H.,Ahmed, S.,Zhao, H.,Elghobashi-Meinhardt, N.,Dai, Y.,Kim, J.H.,McDonald, J.G.,Li, X.,Lee, C.H. Structural and functional insights into Spns2-mediated transport of sphingosine-1-phosphate. Cell, 186:2644-2655.e16, 2023 Cited by PubMed: 37224812 DOI: 10.1016/j.cell.2023.04.028 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.6 Å)

Structure validation