1IB5
 
 | | X-RAY 3D STRUCTURE OF P.LEIOGNATHI CU,ZN SOD MUTANT W83Y | | 分子名称: | COPPER (II) ION, CU,ZN SUPEROXIDE DISMUTASE, ZINC ION | | 著者 | Stroppolo, M.E, Pesce, A, D'Orazio, M, O'Neill, P, Bordo, D, Rosano, C, Milani, M, Battistoni, A, Bolognesi, M, Desideri, A. | | 登録日 | 2001-03-27 | | 公開日 | 2001-05-09 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Single mutations at the subunit interface modulate copper reactivity in Photobacterium leiognathi Cu,Zn superoxide dismutase.
J.Mol.Biol., 308, 2001
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3LTV
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1SDY
 | | STRUCTURE SOLUTION AND MOLECULAR DYNAMICS REFINEMENT OF THE YEAST CU,ZN ENZYME SUPEROXIDE DISMUTASE | | 分子名称: | COPPER (II) ION, COPPER,ZINC SUPEROXIDE DISMUTASE, ZINC ION | | 著者 | Djinovic, K, Gatti, G, Coda, A, Antolini, L, Pelosi, G, Desideri, A, Falconi, M, Marmocchi, F, Rotilio, G, Bolognesi, M. | | 登録日 | 1991-06-14 | | 公開日 | 1994-01-31 | | 最終更新日 | 2017-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structure solution and molecular dynamics refinement of the yeast Cu,Zn enzyme superoxide dismutase.
Acta Crystallogr.,Sect.B, 47, 1991
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6A9O
 | | Rational discovery of a SOD1 tryptophan oxidation inhibitor with therapeutic potential for amyotrophic lateral sclerosis | | 分子名称: | 2'-[(6-oxo-5,6-dihydrophenanthridin-3-yl)carbamoyl][1,1'-biphenyl]-2-carboxylic acid, DIMETHYL SULFOXIDE, Dihydrogen tetrasulfide, ... | | 著者 | Manjula, R, Padmanabhan, B. | | 登録日 | 2018-07-14 | | 公開日 | 2019-07-17 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Rational discovery of a SOD1 tryptophan oxidation inhibitor with therapeutic potential for amyotrophic lateral sclerosis.
J.Biomol.Struct.Dyn., 37, 2019
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1SOS
 | | ATOMIC STRUCTURES OF WILD-TYPE AND THERMOSTABLE MUTANT RECOMBINANT HUMAN CU, ZN SUPEROXIDE DISMUTASE | | 分子名称: | COPPER (II) ION, SULFATE ION, SUPEROXIDE DISMUTASE, ... | | 著者 | Parge, H.E, Hallewell, R.A, Tainer, J.A. | | 登録日 | 1992-02-11 | | 公開日 | 1993-04-15 | | 最終更新日 | 2017-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Atomic structures of wild-type and thermostable mutant recombinant human Cu,Zn superoxide dismutase.
Proc.Natl.Acad.Sci.USA, 89, 1992
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1SDA
 | | CRYSTAL STRUCTURE OF PEROXYNITRITE-MODIFIED BOVINE CU,ZN SUPEROXIDE DISMUTASE | | 分子名称: | COPPER (II) ION, COPPER,ZINC SUPEROXIDE DISMUTASE, ZINC ION | | 著者 | Smith, C.D, Carson, M, Van Der Woerd, M, Chen, J, Ischiropoulos, H, Beckman, J.S. | | 登録日 | 1993-01-13 | | 公開日 | 1993-10-31 | | 最終更新日 | 2017-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal structure of peroxynitrite-modified bovine Cu,Zn superoxide dismutase.
Arch.Biochem.Biophys., 299, 1992
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5J0G
 | | Monomeric Human Cu,Zn Superoxide dismutase, loops IV and VII deleted, apo form, circular permutant P7/8 | | 分子名称: | OXIDOREDUCTASE,Superoxide dismutase [Cu-Zn] | | 著者 | Wang, H, Lang, L, Logan, D, Danielsson, J, Oliveberg, M. | | 登録日 | 2016-03-28 | | 公開日 | 2017-02-01 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Tricking a Protein To Swap Strands.
J. Am. Chem. Soc., 138, 2016
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1OZT
 | | Crystal Structure of apo-H46R Familial ALS Mutant human Cu,Zn Superoxide Dismutase (CuZnSOD) to 2.5A resolution | | 分子名称: | Superoxide dismutase [Cu-Zn] | | 著者 | Elam, J.S, Taylor, A.B, Strange, R, Antonyuk, S, Doucette, P.A, Rodriguez, J.A, Hasnain, S.S, Hayward, L.J, Valentine, J.S, Yeates, T.O, Hart, P.J. | | 登録日 | 2003-04-09 | | 公開日 | 2003-05-27 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Amyloid-like Filaments and Water-filled Nanotubes Formed by SOD1 Mutant Proteins Linked to Familial ALS
Nat.Struct.Biol., 10, 2003
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4FF9
 | | Crystal Structure of cysteinylated WT SOD1. | | 分子名称: | COPPER (II) ION, CYSTEINE, Superoxide dismutase [Cu-Zn], ... | | 著者 | Auclair, J.R, Brodkin, H.R, D'Aquino, J.A, Ringe, D, Petsko, G.A, Agar, J.N. | | 登録日 | 2012-05-31 | | 公開日 | 2013-09-04 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.5003 Å) | | 主引用文献 | Structural consequences of cysteinylation of cu/zn-superoxide dismutase.
Biochemistry, 52, 2013
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6FOL
 | | Domain II of the human copper chaperone in complex with human Cu,Zn superoxide dismutase | | 分子名称: | 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, Copper chaperone for superoxide dismutase, GLYCEROL, ... | | 著者 | Sala, F.A, Wright, G.S.A, Antonyuk, S.V, Garratt, R.C, Hasnain, S.S. | | 登録日 | 2018-02-07 | | 公開日 | 2019-01-30 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | Molecular recognition and maturation of SOD1 by its evolutionarily destabilised cognate chaperone hCCS.
Plos Biol., 17, 2019
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2WWN
 | | Yersinia pseudotuberculosis Superoxide Dismutase C with bound Azide | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, AZIDE ION, SUPEROXIDE DISMUTASE [CU-ZN], ... | | 著者 | Basak, A.K, Duffield, M.L, Naylor, C.E, Huyet, J, Titball, R.W. | | 登録日 | 2009-10-26 | | 公開日 | 2010-11-03 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Crystal Structure of the Yersinia Pseudotuberculosis Superoxide Dismutase (Sodc)
To be Published
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4RVP
 | | Crystal structure of superoxide dismutase from sedum alfredii | | 分子名称: | ZINC ION, superoxide dismutase | | 著者 | Qiu, R, Li, C, Zhai, J, Tang, L, Zhang, H, Yuan, M, Hu, X. | | 登録日 | 2014-11-27 | | 公開日 | 2015-12-16 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | The positive effects of Cd and Cd-Zn relationship in the
Zn-related physiological processes involved in growth in the Zn/Cd hyperaccumulator Sedum alfredii
To be Published
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4MCN
 | | Human SOD1 C57S Mutant, Metal-free | | 分子名称: | SULFATE ION, Superoxide dismutase [Cu-Zn] | | 著者 | Sea, K, Sohn, S.H, Durazo, A, Sheng, Y, Shaw, B, Cao, X, Taylor, A.B, Whitson, L.J, Holloway, S.P, Hart, P.J, Cabelli, D.E, Gralla, E.B, Valentine, J.S. | | 登録日 | 2013-08-21 | | 公開日 | 2014-08-27 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Insights into the role of the unusual disulfide bond in copper-zinc superoxide dismutase.
J.Biol.Chem., 290, 2015
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7B4P
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7FB9
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2ZKX
 | | Crystal structure of human Cu-Zn superoxide dismutase mutant G85R in space group I212121 | | 分子名称: | COPPER (I) ION, Superoxide dismutase [Cu-Zn], ZINC ION | | 著者 | Yoshikawa, S, Kukimoto-Niino, M, Ito, K, Chen, L, Fu, Z.Q, Chrzas, J, Wang, B.C, Shirouzu, M, Urushitani, M, Takahashi, R, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2008-03-31 | | 公開日 | 2009-03-24 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.72 Å) | | 主引用文献 | Crystal structure of human Cu-Zn superoxide dismutase mutant G85R in space group I212121
To be Published
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1DO5
 | | HUMAN COPPER CHAPERONE FOR SUPEROXIDE DISMUTASE DOMAIN II | | 分子名称: | HUMAN COPPER CHAPERONE FOR SUPEROXIDE DISMUTASE DOMAIN II, ZINC ION | | 著者 | Lamb, A.L, Wernimont, A.K, Pufahl, R.A, O'Halloran, T.V, Rosenzweig, A.C. | | 登録日 | 1999-12-18 | | 公開日 | 2000-12-18 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | Crystal structure of the second domain of the human copper chaperone for superoxide dismutase.
Biochemistry, 39, 2000
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6SPK
 | | A4V MUTANT OF HUMAN SOD1 WITH EBSELEN DERIVATIVE 6 | | 分子名称: | 2-selanyl-~{N}-[3-[4-(trifluoromethyl)phenyl]phenyl]benzamide, CHLORIDE ION, DIMETHYL SULFOXIDE, ... | | 著者 | Chantadul, V, Amporndanai, K, Wright, G, Shahid, M, Antonyuk, S, Hasnain, S. | | 登録日 | 2019-09-01 | | 公開日 | 2020-03-18 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.77 Å) | | 主引用文献 | Ebselen as template for stabilization of A4V mutant dimer for motor neuron disease therapy.
Commun Biol, 3, 2020
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4BD4
 | | Monomeric Human Cu,Zn Superoxide dismutase, loops IV and VII deleted, apo form, mutant H43F | | 分子名称: | GLYCEROL, SUPEROXIDE DISMUTASE [CU-ZN] | | 著者 | Awad, W, Saraboji, K, Danielsson, J, Lang, L, Kurnik, M, Marklund, S.L, Oliveberg, M, Logan, D.T. | | 登録日 | 2012-10-04 | | 公開日 | 2013-02-27 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.78 Å) | | 主引用文献 | Global Structural Motions from the Strain of a Single Hydrogen Bond.
Proc.Natl.Acad.Sci.USA, 110, 2013
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6SPI
 | | A4V MUTANT OF HUMAN SOD1 WITH EBSELEN DERIVATIVE 4 | | 分子名称: | SULFATE ION, Superoxide dismutase [Cu-Zn], ZINC ION, ... | | 著者 | Chantadul, V, Amporndanai, K, Wright, G, Antonyuk, S, Hasnain, S. | | 登録日 | 2019-09-01 | | 公開日 | 2020-03-18 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Ebselen as template for stabilization of A4V mutant dimer for motor neuron disease therapy.
Commun Biol, 3, 2020
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1FUN
 | | SUPEROXIDE DISMUTASE MUTANT WITH LYS 136 REPLACED BY GLU, CYS 6 REPLACED BY ALA AND CYS 111 REPLACED BY SER (K136E, C6A, C111S) | | 分子名称: | COPPER (II) ION, SULFATE ION, SUPEROXIDE DISMUTASE, ... | | 著者 | Lo, T.P, Tainer, J.A, Getzoff, E.D. | | 登録日 | 1998-07-23 | | 公開日 | 1999-07-23 | | 最終更新日 | 2021-11-03 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | Computational, pulse-radiolytic, and structural investigations of lysine-136 and its role in the electrostatic triad of human Cu,Zn superoxide dismutase.
Proteins, 29, 1997
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1JK9
 | | Heterodimer between H48F-ySOD1 and yCCS | | 分子名称: | SULFATE ION, ZINC ION, copper chaperone for superoxide dismutase, ... | | 著者 | Lamb, A.L, Torres, A.S, O'Halloran, T.V, Rosenzweig, A.C. | | 登録日 | 2001-07-11 | | 公開日 | 2001-09-05 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Heterodimeric structure of superoxide dismutase in complex with its metallochaperone.
Nat.Struct.Biol., 8, 2001
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7VZF
 | | Cryo-EM structure of amyloid fibril formed by full-length human SOD1 | | 分子名称: | Superoxide dismutase [Cu-Zn] | | 著者 | Wang, L.Q, Ma, Y.Y, Yuan, H.Y, Zhao, K, Zhang, M.Y, Wang, Q, Huang, X, Xu, W.C, Chen, J, Li, D, Zhang, D.L, Zou, L.Y, Yin, P, Liu, C, Liang, Y. | | 登録日 | 2021-11-16 | | 公開日 | 2022-06-29 | | 実験手法 | ELECTRON MICROSCOPY (2.95 Å) | | 主引用文献 | Cryo-EM structure of an amyloid fibril formed by full-length human SOD1 reveals its conformational conversion.
Nat Commun, 13, 2022
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7RH7
 | | Mycobacterial CIII2CIV2 supercomplex, Telacebec (Q203) bound | | 分子名称: | (2R)-2-(hexadecanoyloxy)-3-{[(S)-hydroxy{[(1R,2R,3R,4R,5R,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propyl (9S)-9-methyloctadecanoate, (2R)-3-(((2-aminoethoxy)(hydroxy)phosphoryl)oxy)-2-(palmitoyloxy)propyl (E)-octadec-9-enoate, (2S)-1-(hexadecanoyloxy)propan-2-yl (10S)-10-methyloctadecanoate, ... | | 著者 | Di Trani, J.M, Yanofsky, D.J, Rubinstein, J.L. | | 登録日 | 2021-07-16 | | 公開日 | 2021-08-04 | | 最終更新日 | 2022-02-23 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Structure of mycobacterial CIII 2 CIV 2 respiratory supercomplex bound to the tuberculosis drug candidate telacebec (Q203).
Elife, 10, 2021
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7RH5
 | | Mycobacterial CIII2CIV2 supercomplex, Inhibitor free | | 分子名称: | (2R)-2-(hexadecanoyloxy)-3-{[(S)-hydroxy{[(1R,2R,3R,4R,5R,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propyl (9S)-9-methyloctadecanoate, (2R)-3-(((2-aminoethoxy)(hydroxy)phosphoryl)oxy)-2-(palmitoyloxy)propyl (E)-octadec-9-enoate, (2S)-1-(hexadecanoyloxy)propan-2-yl (10S)-10-methyloctadecanoate, ... | | 著者 | Di Trani, J.M, Yanofsky, D.J, Rubinstein, J.L. | | 登録日 | 2021-07-16 | | 公開日 | 2021-08-04 | | 最終更新日 | 2021-11-10 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Structure of mycobacterial CIII 2 CIV 2 respiratory supercomplex bound to the tuberculosis drug candidate telacebec (Q203).
Elife, 10, 2021
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