6SPI

A4V MUTANT OF HUMAN SOD1 WITH EBSELEN DERIVATIVE 4

Summary for 6SPI

Entry DOI	10.2210/pdb6spi/pdb
Descriptor	Superoxide dismutase [Cu-Zn], ~{N}-[(4-chlorophenyl)methyl]-2-selanyl-benzamide, ZINC ION, ... (5 entities in total)
Functional Keywords	a4v sod1 mutant, ebselen, ebselen derivatives, oxidoreductase
Biological source	Homo sapiens (Human)
Total number of polymer chains	12
Total formula weight	198251.75
Authors	Chantadul, V.,Amporndanai, K.,Wright, G.,Antonyuk, S.,Hasnain, S. (deposition date: 2019-09-01, release date: 2020-03-18, Last modification date: 2024-01-24)
Primary citation	Chantadul, V.,Wright, G.S.A.,Amporndanai, K.,Shahid, M.,Antonyuk, S.V.,Washbourn, G.,Rogers, M.,Roberts, N.,Pye, M.,O'Neill, P.M.,Hasnain, S.S. Ebselen as template for stabilization of A4V mutant dimer for motor neuron disease therapy. Commun Biol, 3:97-97, 2020 Cited by PubMed: 32139772 DOI: 10.1038/s42003-020-0826-3 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.8 Å)

Structure validation