6A9O
Rational discovery of a SOD1 tryptophan oxidation inhibitor with therapeutic potential for amyotrophic lateral sclerosis
Summary for 6A9O
Entry DOI | 10.2210/pdb6a9o/pdb |
Descriptor | Superoxide dismutase [Cu-Zn], ZINC ION, DIMETHYL SULFOXIDE, ... (7 entities in total) |
Functional Keywords | dismutase, dimer, oxidation, oxidoreductase-inhibitor complex, oxidoreductase/inhibitor |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 10 |
Total formula weight | 161526.16 |
Authors | Manjula, R.,Padmanabhan, B. (deposition date: 2018-07-14, release date: 2019-07-17, Last modification date: 2023-11-22) |
Primary citation | Manjula, R.,Unni, S.,Wright, G.S.A.,Bharath M M, S.,Padmanabhan, B. Rational discovery of a SOD1 tryptophan oxidation inhibitor with therapeutic potential for amyotrophic lateral sclerosis. J.Biomol.Struct.Dyn., 37:3936-3946, 2019 Cited by PubMed: 30286701DOI: 10.1080/07391102.2018.1531787 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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