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1C8O
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2.9 A STRUCTURE OF CLEAVED VIRAL SERPIN CRMA
分子名称: ICE INHIBITOR
著者Simonovic, M, Gettins, P.G.W, Volz, K.
登録日2000-06-01
公開日2000-09-06
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal structure of viral serpin crmA provides insights into its mechanism of cysteine proteinase inhibition.
Protein Sci., 9, 2000
1D5S
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BU of 1d5s by Molmil
CRYSTAL STRUCTURE OF CLEAVED ANTITRYPSIN POLYMER
分子名称: P1-ARG ANTITRYPSIN
著者Dunstone, M.A, Dai, W, Whisstock, J.C, Rossjohn, J, Pike, R.N, Feil, S.C, Le Bonneic, B.F, Parker, M.W, Bottomley, S.P.
登録日1999-10-11
公開日2000-04-02
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Cleaved antitrypsin polymers at atomic resolution.
Protein Sci., 9, 2000
1DB2
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CRYSTAL STRUCTURE OF NATIVE PLASMINOGEN ACTIVATOR INHIBITOR-1
分子名称: PLASMINOGEN ACTIVATOR INHIBITOR-1
著者Nar, H, Bauer, M, Stassen, J.M, Lang, D, Gils, A, Declerck, P.
登録日1999-11-02
公開日1999-11-10
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Plasminogen activator inhibitor 1. Structure of the native serpin, comparison to its other conformers and implications for serpin inactivation.
J.Mol.Biol., 297, 2000
1DVN
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LATENT FORM OF PLASMINOGEN ACTIVATOR INHIBITOR-1 (PAI-1)
分子名称: PLASMINOGEN ACTIVATOR INHIBITOR-1
著者Stout, T.J, Graham, H, Buckley, D.I, Matthews, D.J.
登録日2000-01-21
公開日2000-09-13
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structures of active and latent PAI-1: a possible stabilizing role for chloride ions.
Biochemistry, 39, 2000
1E03
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PLASMA ALPHA ANTITHROMBIN-III AND PENTASACCHARIDE
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3,4-di-O-methyl-2,6-di-O-sulfo-alpha-D-glucopyranose-(1-4)-2,3-di-O-methyl-beta-D-glucopyranuronic acid-(1-4)-2,3,6-tri-O-sulfo-alpha-D-glucopyranose-(1-4)-3-O-methyl-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-methyl 2,3,6-tri-O-sulfo-alpha-D-glucopyranoside, ...
著者McCoy, A.J, Jin, L, Abrahams, J.-P, Skinner, R, Carrell, R.W.
登録日2000-03-09
公開日2000-06-02
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structure of Beta-Antithrombin and the Effect of Glycosylation on Antithrombin'S Heparin Affinity and Activity.
J.Mol.Biol., 326, 2003
1DZH
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P14-FLUORESCEIN-N135Q-S380C-ANTITHROMBIN-III
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ANTITHROMBIN-III, ...
著者Mccoy, A.J, Huntington, J.A, Carrell, R.W.
登録日2000-02-28
公開日2000-05-26
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献The Conformational Activation of Antithrombin. A 2. 85-A Structure of a Fluorescein Derivative Reveals an Electrostatic Link between the Hinge and Heparin Binding Regions.
J.Biol.Chem., 275, 2000
1E05
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PLASMA ALPHA ANTITHROMBIN-III
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ANTITHROMBIN-III, ...
著者McCoy, A.J, Skinner, R, Abrahams, J.-P, Pei, X.Y, Carrell, R.W.
登録日2000-03-09
公開日2000-06-02
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.62 Å)
主引用文献Structure of Beta-Antithrombin and the Effect of Glycosylation on Antithrombin'S Heparin Affinity and Activity.
J.Mol.Biol., 326, 2003
1DZG
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N135Q-S380C-ANTITHROMBIN-III
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ANTITHROMBIN-III, ...
著者McCoy, A.J, Huntington, J.A, Carrell, R.W.
登録日2000-02-28
公開日2000-05-26
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The Conformational Activation of Antithrombin. A 2. 85-A Structure of a Fluorescein Derivative Reveals an Electrostatic Link between the Hinge and Heparin Binding Regions.
J.Biol.Chem., 275, 2000
1E04
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PLASMA BETA ANTITHROMBIN-III
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ANTITHROMBIN-III, GLYCEROL, ...
著者Mccoy, A.J, Skinner, R, Abrahams, J.-P, Pei, X.Y, Carrell, R.W.
登録日2000-03-09
公開日2000-06-02
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure of Beta-Antithrombin and the Effect of Glycosylation on Antithrombin'S Heparin Affinity and Activity.
J.Mol.Biol., 326, 2003
1DVM
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BU of 1dvm by Molmil
ACTIVE FORM OF HUMAN PAI-1
分子名称: CHLORIDE ION, PLASMINOGEN ACTIVATOR INHIBITOR-1
著者Stout, T.J, Graham, H, Buckley, D.I, Matthews, D.J.
登録日2000-01-21
公開日2000-09-06
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structures of active and latent PAI-1: a possible stabilizing role for chloride ions.
Biochemistry, 39, 2000
6FTP
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BU of 6ftp by Molmil
Crystal form 1 of Alpha1-antichymotrypsin variant DBS-II-allo: an allosterically modulated drug-binding serpin for doxorubicin
分子名称: 1,2-ETHANEDIOL, Alpha-1-antichymotrypsin, DOXORUBICIN
著者Schmidt, K, Muller, Y.A.
登録日2018-02-22
公開日2018-05-23
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Design of an allosterically modulated doxycycline and doxorubicin drug-binding protein.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6GWQ
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Crystal Structure of Stabilized Active Plasminogen Activator Inhibitor-1 (PAI-1-stab) in Complex with an Inhibitory Nanobody (VHH-2g-42)
分子名称: Plasminogen Activator Inhibitor-1, VHH-2g-42
著者Sillen, M, Weeks, S.D, Strelkov, S.V, Declerck, P.J.
登録日2018-06-25
公開日2020-01-01
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.32 Å)
主引用文献Molecular mechanism of two nanobodies that inhibit PAI-1 activity reveals a modulation at distinct stages of the PAI-1/plasminogen activator interaction.
J.Thromb.Haemost., 18, 2020
6GWP
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Crystal Structure of Stabilized Active Plasminogen Activator Inhibitor-1 (PAI-1-stab) in Complex with Two Inhibitory Nanobodies (VHH-2g-42, VHH-2w-64)
分子名称: Plasminogen Activator Inhibitor-1, VHH-2g-42, VHH-2w-64
著者Sillen, M, Weeks, S.D, Strelkov, S.V, Declerck, P.J.
登録日2018-06-25
公開日2020-01-01
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献Molecular mechanism of two nanobodies that inhibit PAI-1 activity reveals a modulation at distinct stages of the PAI-1/plasminogen activator interaction.
J.Thromb.Haemost., 18, 2020
6GWN
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Crystal Structure of Stabilized Active Plasminogen Activator Inhibitor-1 (PAI-1-W175F) in Complex with Two Inhibitory Nanobodies (VHH-2g-42, VHH-2w-64)
分子名称: Plasminogen activator inhibitor 1, VHH-2g-42, VHH-2w-64
著者Sillen, M, Weeks, S.D, Strelkov, S.V, Declerck, P.J.
登録日2018-06-25
公開日2020-01-01
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Molecular mechanism of two nanobodies that inhibit PAI-1 activity reveals a modulation at distinct stages of the PAI-1/plasminogen activator interaction.
J.Thromb.Haemost., 18, 2020
6HGL
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Crystal structure of Alpha1-antichymotrypsin variant NewBG-III: a new binding globulin in complex with testosterone
分子名称: Alpha-1-antichymotrypsin, TESTOSTERONE
著者Schmidt, K, Muller, Y.A.
登録日2018-08-23
公開日2019-05-29
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献NewBG: A surrogate corticosteroid-binding globulin with an unprecedentedly high ligand release efficacy.
J.Struct.Biol., 207, 2019
6HGK
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BU of 6hgk by Molmil
Crystal structure of Alpha1-antichymotrypsin variant NewBG-III: a new binding globulin in complex with progesterone
分子名称: 1,2-ETHANEDIOL, Alpha-1-antichymotrypsin, PROGESTERONE
著者Schmidt, K, Muller, Y.A.
登録日2018-08-23
公開日2019-05-29
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.855 Å)
主引用文献NewBG: A surrogate corticosteroid-binding globulin with an unprecedentedly high ligand release efficacy.
J.Struct.Biol., 207, 2019
6HGJ
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Crystal structure of Alpha1-antichymotrypsin variant NewBG-III: a new binding globulin in complex with aldosterone
分子名称: 1,2-ETHANEDIOL, ALDOSTERONE, Alpha-1-antichymotrypsin
著者Schmidt, K, Muller, Y.A.
登録日2018-08-23
公開日2019-05-29
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.825 Å)
主引用文献NewBG: A surrogate corticosteroid-binding globulin with an unprecedentedly high ligand release efficacy.
J.Struct.Biol., 207, 2019
6HGN
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Crystal structure of Alpha1-antichymotrypsin variant DBS-II-allo-L55V: an allosterically controlled doxorubicin-binding serpin with an unprecedentedly high ligand release efficacy
分子名称: 1,2-ETHANEDIOL, Alpha-1-antichymotrypsin
著者Schmidt, K, Muller, Y.A.
登録日2018-08-23
公開日2019-05-29
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.478 Å)
主引用文献NewBG: A surrogate corticosteroid-binding globulin with an unprecedentedly high ligand release efficacy.
J.Struct.Biol., 207, 2019
6HGD
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Crystal structure of Alpha1-antichymotrypsin variant NewBG-0: a new binding globulin variant that is devoid of any cortisol-binding capabilities
分子名称: Alpha-1-antichymotrypsin
著者Gardill, B.R, Schmidt, K, Muller, Y.A.
登録日2018-08-23
公開日2019-05-29
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献NewBG: A surrogate corticosteroid-binding globulin with an unprecedentedly high ligand release efficacy.
J.Struct.Biol., 207, 2019
6HGG
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Crystal structure of Alpha1-antichymotrypsin variant NewBG-III: a new binding globulin in complex with cortisol
分子名称: (11alpha,14beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione, 1,2-ETHANEDIOL, Alpha-1-antichymotrypsin
著者Schmidt, K, Muller, Y.A.
登録日2018-08-23
公開日2019-05-29
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.787 Å)
主引用文献NewBG: A surrogate corticosteroid-binding globulin with an unprecedentedly high ligand release efficacy.
J.Struct.Biol., 207, 2019
6HGM
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Crystal structure of Alpha1-antichymotrypsin variant NewBG-III-allo: an allosterically controlled new binding globulin with an unprecedentedly high ligand release efficacy
分子名称: 1,2-ETHANEDIOL, Alpha-1-antichymotrypsin, CALCIUM ION, ...
著者Schmidt, K, Muller, Y.A.
登録日2018-08-23
公開日2019-05-29
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.369 Å)
主引用文献NewBG: A surrogate corticosteroid-binding globulin with an unprecedentedly high ligand release efficacy.
J.Struct.Biol., 207, 2019
6HGF
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Crystal structure of Alpha1-antichymotrypsin variant NewBG-II: a new binding globulin in complex with cortisol
分子名称: (11alpha,14beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione, 1,2-ETHANEDIOL, Alpha-1-antichymotrypsin
著者Schmidt, K, Muller, Y.A.
登録日2018-08-23
公開日2019-05-29
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.651 Å)
主引用文献NewBG: A surrogate corticosteroid-binding globulin with an unprecedentedly high ligand release efficacy.
J.Struct.Biol., 207, 2019
6HGH
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Crystal structure of Alpha1-antichymotrypsin variant NewBG-III: a new binding globulin without any bound ligand
分子名称: Alpha-1-antichymotrypsin, MALONIC ACID, alpha1-Antichymotrypsin
著者Schmidt, K, Muller, Y.A.
登録日2018-08-23
公開日2019-05-29
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献NewBG: A surrogate corticosteroid-binding globulin with an unprecedentedly high ligand release efficacy.
J.Struct.Biol., 207, 2019
6HX4
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Fab fragment of a native monomer-selective antibody in complex with alpha-1-antitrypsin
分子名称: Alpha-1-antitrypsin, Fab 1D9 heavy chain, Fab 1D9 light chain
著者Elliston, E.L.K, Miranda, E, Perez, J, Jagger, A.M, Lomas, D.A, Irving, J.A.
登録日2018-10-15
公開日2019-10-30
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Characterisation of a monoclonal antibody conformationally-selective for native alpha-1-antitrypsin
To Be Published
6HGI
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Crystal structure of Alpha1-antichymotrypsin variant NewBG-III: a new binding globulin in complex with corticosterone
分子名称: Alpha-1-antichymotrypsin, CORTICOSTERONE
著者Schmidt, K, Muller, Y.A.
登録日2018-08-23
公開日2019-05-29
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.517 Å)
主引用文献NewBG: A surrogate corticosteroid-binding globulin with an unprecedentedly high ligand release efficacy.
J.Struct.Biol., 207, 2019

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