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1ZL7
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Crystal structure of catalytically-active phospholipase A2 with bound calcium
分子名称: CALCIUM ION, GLYCEROL, hypotensive phospholipase A2
著者Murakami, M.T, Cintra, A.C, Gabdoulkhakov, A, Genov, N, Betzel, C, Arni, R.K.
登録日2005-05-05
公開日2006-04-25
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Insights into metal ion binding in phospholipases A(2): ultra high-resolution crystal structures of an acidic phospholipase A(2) in the Ca(2+) free and bound states.
Biochimie, 88, 2006
1ZM6
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Crystal structure of the complex formed beween a group I phospholipase A2 and designed penta peptide Leu-Ala-Ile-Tyr-Ser at 2.6A resolution
分子名称: ACETATE ION, Phospholipase A2 isoform 3, designed penta peptide Leu-Ala-Ile-Tyr-Ser
著者Singh, R.K, Singh, N, Jabeen, T, Sharma, S, Dey, S, Singh, T.P.
登録日2005-05-10
公開日2005-06-21
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structure of the complex of group I PLA2 with a group II-specific peptide Leu-Ala-Ile-Tyr-Ser (LAIYS) at 2.6 A resolution.
J.Drug Target., 13, 2005
1ZR8
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Crystal Structure of the complex formed between group II phospholipase A2 and a plant alkaloid ajmaline at 2.0A resolution
分子名称: ACETIC ACID, AJMALINE, Phospholipase A2 VRV-PL-VIIIa, ...
著者Mahendra, M, Singh, N, Kaur, P, Sharma, S, Singh, T.P.
登録日2005-05-19
公開日2005-06-14
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Crystal Structure of the complex formed between group II phospholipase A2 and a plant alkaloid ajmaline at 2.0A resolution
To be Published
1ZWP
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The atomic resolution Crystal structure of the Phospholipase A2 (PLA2) complex with Nimesulide reveals its weaker binding to PLA2
分子名称: 4-NITRO-2-PHENOXYMETHANESULFONANILIDE, METHANOL, Phospholipase A2 VRV-PL-VIIIa, ...
著者Prem Kumar, R, Singh, N, Sharma, S, Kaur, P, Singh, T.P.
登録日2005-06-04
公開日2005-07-26
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献The atomic resolution Crystal structure of the Phospholipase A2 (PLA2) complex with Nimesulide reveals its weaker binding to PLA2
To be Published
1ZYX
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Crystal structure of the complex of a group IIA phospholipase A2 with a synthetic anti-inflammatory agent licofelone at 1.9A resolution
分子名称: Phospholipase A2 VRV-PL-VIIIa, SULFATE ION, [6-(4-CHLOROPHENYL)-2,2-DIMETHYL-7-PHENYL-2,3-DIHYDRO-1H-PYRROLIZIN-5-YL]ACETIC ACID
著者Singh, N, Jabeen, T, Sharma, S, Bhushan, A, Singh, T.P.
登録日2005-06-13
公開日2005-06-28
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Crystal structure of the complex of a group IIA phospholipase A2 with a synthetic anti-inflammatory agent licofelone at 1.9A resolution
To be Published
2AOZ
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Crystal structure of the myotoxin-II from Atropoides nummifer venom
分子名称: Phospholipase A2 homolog, SULFATE ION
著者Melo, C.C, Murakami, M.T, Angulo, Y, Lomonte, B, Arni, R.K.
登録日2005-08-15
公開日2006-07-25
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.08 Å)
主引用文献Structure of myotoxin II, a catalytically inactive Lys49 phospholipase A2 homologue from Atropoides nummifer venom.
Acta Crystallogr.,Sect.F, 62, 2006
2ARM
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Crystal Structure of the Complex of Phospholipase A2 with a natural compound atropine at 1.2 A resolution
分子名称: (1R,5S)-8-METHYL-8-AZABICYCLO[3.2.1]OCT-3-YL (2R)-3-HYDROXY-2-PHENYLPROPANOATE, Phospholipase A2 VRV-PL-VIIIa, SULFATE ION
著者Singh, N, Pal, A, Jabeen, T, Sharma, S, Perbandt, M, Betzel, C, Singh, T.P.
登録日2005-08-20
公開日2005-09-20
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.23 Å)
主引用文献Crystal structures of the complexes of a group IIA phospholipase A2 with two natural anti-inflammatory agents, anisic acid, and atropine reveal a similar mode of binding
Proteins, 64, 2006
2AZZ
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Crystal Structure of Porcine Pancreatic Phospholipase A2 in Complex with Taurocholate
分子名称: CALCIUM ION, CHLORIDE ION, Phospholipase A2, ...
著者Pan, Y.H, Bahnson, B.J, Jain, M.K.
登録日2005-09-12
公開日2006-11-14
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural basis for bile salt inhibition of pancreatic phospholipase A2.
J.Mol.Biol., 369, 2007
2B03
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Crystal Structure of Porcine Pancreatic Phospholipase A2 in Complex with Taurochenodeoxycholate
分子名称: CALCIUM ION, Phospholipase A2, major isoenzyme, ...
著者Pan, Y.H, Bahnson, B.J, Jain, M.K.
登録日2005-09-12
公開日2006-11-14
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural basis for bile salt inhibition of pancreatic phospholipase A2.
J.Mol.Biol., 369, 2007
2B01
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Crystal Structure of Porcine Pancreatic Phospholipase A2 in Complex with Taurochenodeoxycholate
分子名称: CALCIUM ION, CHLORIDE ION, Phospholipase A2, ...
著者Pan, Y.H, Bahnson, B.J, Jain, M.K.
登録日2005-09-12
公開日2006-11-14
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural basis for bile salt inhibition of pancreatic phospholipase A2.
J.Mol.Biol., 369, 2007
2B00
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Crystal Structure of Porcine Pancreatic Phospholipase A2 in Complex with Glycocholate
分子名称: CALCIUM ION, GLYCOCHOLIC ACID, Phospholipase A2, ...
著者Pan, Y.H, Bahnson, B.J, Jain, M.K.
登録日2005-09-12
公開日2006-11-14
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural basis for bile salt inhibition of pancreatic phospholipase A2.
J.Mol.Biol., 369, 2007
2B04
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Crystal Structure of Porcine Pancreatic Phospholipase A2 in Complex with Glycochenodeoxycholate
分子名称: CALCIUM ION, CHLORIDE ION, GLYCOCHENODEOXYCHOLIC ACID, ...
著者Pan, Y.H, Bahnson, B.J, Jain, M.K.
登録日2005-09-12
公開日2006-11-14
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural basis for bile salt inhibition of pancreatic phospholipase A2.
J.Mol.Biol., 369, 2007
2AZY
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Crystal Structure of Porcine Pancreatic Phospholipase A2 in Complex with Cholate
分子名称: CALCIUM ION, CHOLIC ACID, Phospholipase A2, ...
著者Pan, Y.H, Bahnson, B.J, Jain, M.K.
登録日2005-09-12
公開日2006-11-14
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural basis for bile salt inhibition of pancreatic phospholipase A2.
J.Mol.Biol., 369, 2007
2B17
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Specific binding of non-steroidal anti-inflammatory drugs (NSAIDs) to phospholipase A2: Crystal structure of the complex formed between phospholipase A2 and diclofenac at 2.7 A resolution:
分子名称: 2-[2,6-DICHLOROPHENYL)AMINO]BENZENEACETIC ACID, Phospholipase A2 VRV-PL-VIIIa, SULFATE ION
著者Singh, N, Jabeen, T, Sharma, S, Singh, T.P.
登録日2005-09-15
公開日2005-10-04
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.71 Å)
主引用文献Specific binding of non-steroidal anti-inflammatory drugs (NSAIDs) to phospholipase A2: structure of the complex formed between phospholipase A2 and diclofenac at 2.7 A resolution.
Acta Crystallogr.,Sect.D, 62, 2006
2B96
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Third Calcium ion found in an inhibitor bound phospholipase A2
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 4-METHOXYBENZOIC ACID, CALCIUM ION, ...
著者Sekar, K, Velmurugan, D, Yamane, T, Tsai, M.D.
登録日2005-10-11
公開日2006-03-28
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Third Calcium ion found in an inhibitor bound phospholipase A2
Acta Crystallogr.,Sect.D, 62, 2006
2BAX
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Atomic Resolution Structure of the Double Mutant (K53,56M) of Bovine Pancreatic Phospholipase A2
分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, ...
著者Sekar, K, Yogavel, M, Velmurugan, D, Dauter, Z, Dauter, M, Tsai, M.D.
登録日2005-10-15
公開日2005-10-25
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献Atomic resolution (0.97 A) structure of the triple mutant (K53,56,121M) of bovine pancreatic phospholipase A2.
Acta Crystallogr.,Sect.F, 61, 2005
2BCH
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A possible of Second calcium ion in interfacial binding: Atomic and Medium resolution crystal structures of the quadruple mutant of phospholipase A2
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, CHLORIDE ION, ...
著者Sekar, K, Yogavel, M, Velmurugan, D, Poi, M.J, Dauter, Z, Tsai, M.D.
登録日2005-10-19
公開日2006-07-04
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献Suggestive evidence for the involvement of the second calcium and surface loop in interfacial binding: monoclinic and trigonal crystal structures of a quadruple mutant of phospholipase A(2).
Acta Crystallogr.,Sect.D, 62, 2006
2BD1
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A possible role of the second calcium ion in interfacial binding: Atomic and medium resolution crystal structures of the quadruple mutant of phospholipase A2
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, Phospholipase A2
著者Sekar, K, Velmurugan, D, Tsai, M.D.
登録日2005-10-19
公開日2006-07-04
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Suggestive evidence for the involvement of the second calcium and surface loop in interfacial binding: monoclinic and trigonal crystal structures of a quadruple mutant of phospholipase A(2).
Acta Crystallogr.,Sect.D, 62, 2006
2FNX
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Design of Specific Peptide Inhibitors of Phospholipase A2 (PLA2): Crystal Structure of the Complex of PLA2 with a Highly Potent Peptide Val-Ile-Ala-Lys at 2.7A Resolution
分子名称: Inhibitor peptide, Phospholipase A2 VRV-PL-VIIIa, SULFATE ION
著者Singh, N, Srivastava, P, Sharma, S, Dey, S, Singh, T.P.
登録日2006-01-11
公開日2006-01-24
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Design of Specific Peptide Inhibitors of Phospholipase A2 (PLA2): Crystal Structure of the Complex of PLA2 with a Highly Potent Peptide Val-Ile-Ala-Lys at 2.7A Resolution
To be Published
2G58
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Crystal structure of a complex of phospholipase A2 with a designed peptide inhibitor Dehydro-Ile-Ala-Arg-Ser at 0.98 A resolution
分子名称: (PHQ)IARS, Phospholipase A2 VRV-PL-VIIIa, SULFATE ION
著者Prem Kumar, R, Singh, N, Somvanshi, R.K, Ethayathulla, A.S, Dey, S, Sharma, S, Kaur, P, Perbandt, M, Betzel, C, Singh, T.P.
登録日2006-02-22
公開日2006-03-28
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (0.98 Å)
主引用文献Crystal structure of a complex of phospholipase A2 with a designed peptide inhibitor Dehydro-Ile-Ala-Arg-Ser at 0.98 A resolution
To be Published
2GNS
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Design of specific peptide inhibitors of phospholipase A2: Crystal structure of the complex formed between a group II phospholipase A2 and a designed pentapeptide Ala- Leu- Val- Tyr- Lys at 2.3 A resolution
分子名称: ALVYK, Phospholipase A2 VRV-PL-VIIIa, SULFATE ION
著者Singh, N, Sharma, S, Somvanshi, R.K, Dey, S, Singh, T.P.
登録日2006-04-11
公開日2006-04-25
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Design of specific peptide inhibitors of phospholipase A2: Crystal structure of the complex formed between a group II phospholipase A2 and a designed pentapeptide Ala - Leu - Val - Tyr - Lys at 2.3 A resolution
To be Published
2DO2
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Design of specific inhibitors of phospholipase A2: Crystal structure of the complex formed between a group II Cys 49 phospholipase A2 and a designed pentapeptide Ala-Leu-Ala-Ser-Lys at 2.6A resolution
分子名称: Ala-Leu-Ala-Ser-Lys, Phospholipase A2 VRV-PL-VIIIa, SULFATE ION
著者Singh, N, Sharma, S, Somvanshi, R.K, Dey, S, Singh, T.P.
登録日2006-04-27
公開日2006-05-16
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Design of specific inhibitors of phospholipase A2: Crystal structure of the complex formed between a group II Cys 49 phospholipase A2 and a designed pentapeptide Ala-Leu-Ala-Ser-Lys at 2.6A resolution
To be Published
2DPZ
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Structure of the complex of phospholipase A2 with N-(4-hydroxyphenyl)- acetamide at 2.1 A resolution
分子名称: N-(4-HYDROXYPHENYL)ACETAMIDE (TYLENOL), Phospholipase A2 VRV-PL-VIIIa, SULFATE ION
著者Singh, N, Sharma, S, Singh, T.P.
登録日2006-05-18
公開日2006-06-06
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Phospholipase A2 as a target protein for non-steroidal anti-inflammatory drugs (NSAIDs): Crystal structure of the complex formed between a group II phospholipase A2 and N-(4-hydroxyphenyl) - acetamide at 2.1 resolution
To be Published
2H4C
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Structure of Daboiatoxin (heterodimeric PLA2 venom)
分子名称: Phospholipase A2-II, Phospholipase A2-III
著者Gopalan, G, Thwin, M.M, Gopalakrishnakone, P, Swaminathan, K.
登録日2006-05-24
公開日2007-05-29
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural and pharmacological comparison of daboiatoxin from Daboia russelli siamensis with viperotoxin F and vipoxin from other vipers.
ACTA CRYSTALLOGR.,SECT.D, 63, 2007
2H8I
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Crystal Structure of the Bothropstoxin-I complexed with polyethylene glycol
分子名称: DI(HYDROXYETHYL)ETHER, Phospholipase A2 homolog 1
著者Murakami, M.T, Arni, R.K.
登録日2006-06-07
公開日2007-06-19
最終更新日2022-12-21
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Interfacial surface charge and free accessibility to the PLA2-active site-like region are essential requirements for the activity of Lys49 PLA2 homologues
Toxicon, 49, 2007

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