2DO2

Design of specific inhibitors of phospholipase A2: Crystal structure of the complex formed between a group II Cys 49 phospholipase A2 and a designed pentapeptide Ala-Leu-Ala-Ser-Lys at 2.6A resolution

Summary for 2DO2

• Entry DOI: 10.2210/pdb2do2/pdb
• Related: 1Q6V
• Descriptor: Phospholipase A2 VRV-PL-VIIIa, Ala-Leu-Ala-Ser-Lys, SULFATE ION, ... (4 entities in total)
• Functional Keywords: cys 49 phospholipase a2, synthetic pentapeptide, complex, hydrolase
• Biological source: Daboia russellii pulchella; More
• Cellular location: Secreted: P59071
• Total number of polymer chains: 2
• Total formula weight: 14078.30

Authors

Singh, N.,Sharma, S.,Somvanshi, R.K.,Dey, S.,Singh, T.P. (deposition date: 2006-04-27, release date: 2006-05-16, Last modification date: 2023-10-25)

• Primary citation: Singh, N.,Sharma, S.,Somvanshi, R.K.,Dey, S.,Singh, T.P.; Design of specific inhibitors of phospholipase A2: Crystal structure of the complex formed between a group II Cys 49 phospholipase A2 and a designed pentapeptide Ala-Leu-Ala-Ser-Lys at 2.6A resolution; To be Published,

Experimental method

X-RAY DIFFRACTION (2.6 Å)