3KR3
| Crystal structure of IGF-II antibody complex | 分子名称: | 1,2-ETHANEDIOL, Insulin-like growth factor II, antibody-Fab (heavy chain), ... | 著者 | Peat, T.S, Newman, J, Adams, T.E. | 登録日 | 2009-11-17 | 公開日 | 2010-06-16 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | A human monoclonal antibody against insulin-like growth factor-II blocks the growth of human hepatocellular carcinoma cell lines in vitro and in vivo. Mol.Cancer Ther., 9, 2010
|
|
3KQ6
| Enhancing the Therapeutic Properties of a Protein by a Designed Zinc-Binding Site, Structural principles of a novel long-acting insulin analog | 分子名称: | CHLORIDE ION, Insulin A chain, Insulin B chain, ... | 著者 | Wan, Z.L, Hu, S.Q, Whittaker, L, Phillips, N.B, Whittake, J, Ismail-Beigi, F, Weiss, M.A. | 登録日 | 2009-11-17 | 公開日 | 2010-02-23 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Supramolecular protein engineering: design of zinc-stapled insulin hexamers as a long acting depot. J.Biol.Chem., 285, 2010
|
|
6Q8Q
| |
6QRH
| |
6QRK
| |
6QQ7
| |
6QQG
| |
6S34
| |
6S4J
| |
6S4I
| |
6RVA
| STRUCTURE OF [ASP58]-IGF-I ANALOGUE | 分子名称: | Insulin-like growth factor I | 著者 | Jiracek, J, Zakova, L, Socha, O. | 登録日 | 2019-05-31 | 公開日 | 2019-10-02 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | Mutations at hypothetical binding site 2 in insulin and insulin-like growth factors 1 and 2 result in receptor- and hormone-specific responses. J.Biol.Chem., 294, 2019
|
|
6TC2
| Monoclinic human insulin in complex with p-coumaric acid | 分子名称: | 4'-HYDROXYCINNAMIC ACID, Insulin, PHOSPHATE ION, ... | 著者 | Triandafillidis, D.-P, Parthenios, N, Spiliopoulou, M, Valmas, A, Kosinas, C, Gozzo, F, Reinle-Schmitt, M, Beckers, D, Degen, T, Pop, M, Fitch, A, Wollenhaupt, J, Weiss, M.S, Karavassili, F, Margiolaki, I. | 登録日 | 2019-11-04 | 公開日 | 2020-11-11 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.36 Å) | 主引用文献 | Insulin polymorphism induced by two polyphenols: new crystal forms and advances in macromolecular powder diffraction. Acta Crystallogr D Struct Biol, 76, 2020
|
|
6TYH
| |
1CPH
| CONFORMATIONAL CHANGES IN CUBIC INSULIN CRYSTALS IN THE PH RANGE 7-11 | 分子名称: | 1,2-DICHLOROETHANE, INSULIN (PH 10), SODIUM ION | 著者 | Gursky, O, Badger, J, Li, Y, Caspar, D.L.D. | 登録日 | 1992-10-30 | 公開日 | 1993-01-15 | 最終更新日 | 2017-11-29 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Conformational changes in cubic insulin crystals in the pH range 7-11. Biophys.J., 63, 1992
|
|
1AI0
| R6 HUMAN INSULIN HEXAMER (NON-SYMMETRIC), NMR, 10 STRUCTURES | 分子名称: | PHENOL, R6 INSULIN HEXAMER, ZINC ION | 著者 | Chang, X, Jorgensen, A.M.M, Bardrum, P, Led, J.J. | 登録日 | 1997-04-30 | 公開日 | 1997-11-12 | 最終更新日 | 2022-02-16 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structures of the R6 human insulin hexamer. Biochemistry, 36, 1997
|
|
1A7F
| |
7QGF
| Cubic Insulin SAD phasing at 14.2 keV | 分子名称: | Insulin A chain, Insulin B chain | 著者 | Nanao, M.H, Basu, S. | 登録日 | 2021-12-08 | 公開日 | 2022-06-01 | 実験手法 | X-RAY DIFFRACTION (1.203 Å) | 主引用文献 | ID23-2: an automated and high-performance microfocus beamline for macromolecular crystallography at the ESRF. J.Synchrotron Radiat., 29, 2022
|
|
1AIY
| R6 HUMAN INSULIN HEXAMER (SYMMETRIC), NMR, 10 STRUCTURES | 分子名称: | PHENOL, R6 INSULIN HEXAMER, ZINC ION | 著者 | Chang, X, Jorgensen, A.M.M, Bardrum, P, Led, J.J. | 登録日 | 1997-04-30 | 公開日 | 1997-11-12 | 最終更新日 | 2022-02-16 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structures of the R6 human insulin hexamer. Biochemistry, 36, 1997
|
|
1B9G
| INSULIN-LIKE-GROWTH-FACTOR-1 | 分子名称: | PROTEIN (GROWTH FACTOR IGF-1) | 著者 | De Wolf, E, Gill, R, Geddes, S, Pitts, J, Wollmer, A, Grotzinger, J. | 登録日 | 1999-02-11 | 公開日 | 1999-02-23 | 最終更新日 | 2023-12-27 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of a mini IGF-1. Protein Sci., 5, 1996
|
|
1B2D
| |
1DPH
| CONFORMATIONAL CHANGES IN CUBIC INSULIN CRYSTALS IN THE PH RANGE 7-11 | 分子名称: | 1,2-DICHLOROETHANE, INSULIN A CHAIN (PH 11), INSULIN B CHAIN (PH 11), ... | 著者 | Gursky, O, Badger, J, Li, Y, Caspar, D.L.D. | 登録日 | 1992-10-30 | 公開日 | 1993-01-15 | 最終更新日 | 2017-11-29 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Conformational changes in cubic insulin crystals in the pH range 7-11. Biophys.J., 63, 1992
|
|
1B2C
| |
7QAC
| The T2 structure of polycrystalline cubic human insulin | 分子名称: | Insulin A chain, Insulin B chain | 著者 | Karavassili, F, Triandafillidis, D.P, Valmas, A, Spiliopoulou, M, Fili, S, Kontou, P, Bowler, M.W, Von Dreele, R.B, Fitch, A, Margiolaki, I. | 登録日 | 2021-11-16 | 公開日 | 2023-06-21 | 最終更新日 | 2024-02-07 | 実験手法 | POWDER DIFFRACTION (2.29 Å) | 主引用文献 | The T 2 structure of polycrystalline cubic human insulin. Acta Crystallogr D Struct Biol, 79, 2023
|
|
1B19
| |
1B2F
| |