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6MHX
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BU of 6mhx by Molmil
Structure of human TRPV3 in the presence of 2-APB in C2 symmetry (2)
分子名称: Transient receptor potential cation channel subfamily V member 3
著者Zubcevic, L, Herzik, M.A, Wu, M, Borschel, W.F, Hirschi, M, Song, A, Lander, G.C, Lee, S.Y.
登録日2018-09-18
公開日2018-10-03
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Conformational ensemble of the human TRPV3 ion channel.
Nat Commun, 9, 2018
6MHW
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BU of 6mhw by Molmil
Structure of human TRPV3 in the presence of 2-APB in C2 symmetry (1)
分子名称: Transient receptor potential cation channel subfamily V member 3
著者Zubcevic, L, Herzik, M.A, Wu, M, Borschel, W.F, Hirschi, M, Song, A, Lander, G.C, Lee, S.Y.
登録日2018-09-18
公開日2018-10-03
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Conformational ensemble of the human TRPV3 ion channel.
Nat Commun, 9, 2018
6BO9
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BU of 6bo9 by Molmil
Cryo-EM structure of human TRPV6 in amphipols
分子名称: Transient receptor potential cation channel subfamily V member 6
著者McGoldrick, L.L, Singh, A.K, Saotome, K, Yelshanskaya, M.V, Twomey, E.C, Grassucci, R.A, Sobolevsky, A.I.
登録日2017-11-18
公開日2017-12-20
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Opening of the human epithelial calcium channel TRPV6.
Nature, 553, 2018
6UW8
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BU of 6uw8 by Molmil
Cryo-EM structure of the human TRPV3 K169A mutant briefly exposed to 2-APB for 3 minutes, determined in lipid nanodisc
分子名称: Transient receptor potential cation channel subfamily V member 3
著者Deng, Z, Yuan, P.
登録日2019-11-04
公開日2020-07-01
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (4.02 Å)
主引用文献Gating of human TRPV3 in a lipid bilayer.
Nat.Struct.Mol.Biol., 27, 2020
6PVN
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BU of 6pvn by Molmil
Cryo-EM structure of mouse TRPV3-Y564A in putative sensitized state at 4 degrees Celsius
分子名称: SODIUM ION, Transient receptor potential cation channel subfamily V member 3
著者Singh, A.K, McGoldrick, L.L, Sobolevsky, A.I.
登録日2019-07-21
公開日2019-10-23
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (4.07 Å)
主引用文献Structural basis of temperature sensation by the TRP channel TRPV3.
Nat.Struct.Mol.Biol., 26, 2019
6OT2
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BU of 6ot2 by Molmil
Structure of the TRPV3 K169A sensitized mutant in apo form at 4.1 A resolution
分子名称: Transient receptor potential cation channel subfamily V member 3
著者Zubcevic, L, Borschel, W.F, Hsu, A.L, Borgnia, M.J, Lee, S.-Y.
登録日2019-05-02
公開日2019-05-22
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Regulatory switch at the cytoplasmic interface controls TRPV channel gating.
Elife, 8, 2019
7AA5
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BU of 7aa5 by Molmil
Human TRPV4 structure in presence of 4a-PDD
分子名称: CALCIUM ION, Transient receptor potential cation channel subfamily V member 4,Green fluorescent protein
著者Botte, M, Ulrich, A.K.G, Adaixo, R, Gnutt, D, Brockmann, A, Bucher, D, Chami, M, Bocquet, M, Ebbinghaus-Kintscher, U, Puetter, V, Becker, A, Egner, U, Stahlberg, H, Hennig, M, Holton, S.J.
登録日2020-09-03
公開日2021-08-18
実験手法ELECTRON MICROSCOPY (4.18 Å)
主引用文献Cryo-EM structural studies of the agonist complexed human TRPV4 ion-channel reveals novel structural rearrangements resulting in an open-conformation
To Be Published
3J5R
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BU of 3j5r by Molmil
Reconstruction of TRPV1 ion channel in complex with capsaicin by single particle cryo-microscopy
分子名称: Transient receptor potential cation channel subfamily V member 1
著者Liao, M, Cao, E, Julius, D, Cheng, Y.
登録日2013-10-28
公開日2013-12-04
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献TRPV1 structures in distinct conformations reveal activation mechanisms.
Nature, 504, 2013
6PBF
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BU of 6pbf by Molmil
ZINC9155420-bound TRPV5 in nanodiscs
分子名称: (1S)-1-(4-oxo-5-phenyl-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl)ethyl [(2S)-3-oxo-3,4-dihydro-2H-1,4-benzothiazin-2-yl]acetate, Transient receptor potential cation channel subfamily V member 5
著者Hughes, T.E.T, Rosario, J.S.D, Kapoor, A, Yazici, A.T, Fluck, E.C, Filizola, M, Rohacs, T, Moiseenkova-Bell, V.Y.
登録日2019-06-13
公開日2019-11-06
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Structure-based characterization of novel TRPV5 inhibitors.
Elife, 8, 2019
6BOA
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BU of 6boa by Molmil
Cryo-EM structure of human TRPV6-R470E in amphipols
分子名称: Transient receptor potential cation channel subfamily V member 6
著者McGoldrick, L.L, Singh, A.K, Saotome, K, Yelshanskaya, M.V, Twomey, E.C, Grassucci, R.A, Sobolevsky, A.I.
登録日2017-11-18
公開日2017-12-20
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Opening of the human epithelial calcium channel TRPV6.
Nature, 553, 2018
3J9P
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BU of 3j9p by Molmil
Structure of the TRPA1 ion channel determined by electron cryo-microscopy
分子名称: Maltose-binding periplasmic protein, Transient receptor potential cation channel subfamily A member 1 chimera
著者Paulsen, C.E, Armache, J.-P, Gao, Y, Cheng, Y, Julius, D.
登録日2015-02-14
公開日2015-04-08
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (4.24 Å)
主引用文献Structure of the TRPA1 ion channel suggests regulatory mechanisms.
Nature, 520, 2015
6DVZ
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BU of 6dvz by Molmil
Cryo-EM structure of mouse TRPV3-Y564A in complex with 2-Aminoethoxydiphenyl borate (2-APB)
分子名称: 2-aminoethyl diphenylborinate, Transient receptor potential cation channel subfamily V member 3
著者Singh, A.K, McGoldrick, L.L, Sobolevsky, A.I.
登録日2018-06-25
公開日2018-09-05
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (4.24 Å)
主引用文献Structure and gating mechanism of the transient receptor potential channel TRPV3.
Nat. Struct. Mol. Biol., 25, 2018
6DVW
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BU of 6dvw by Molmil
Cryo-EM structure of mouse TRPV3
分子名称: Transient receptor potential cation channel subfamily V member 3
著者Singh, A.K, McGoldrick, L.L, Sobolevsky, A.I.
登録日2018-06-25
公開日2018-09-05
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Structure and gating mechanism of the transient receptor potential channel TRPV3.
Nat. Struct. Mol. Biol., 25, 2018
6UW9
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BU of 6uw9 by Molmil
Cryo-EM structure of the human TRPV3 K169A mutant in the presence of 2-APB, determined in lipid nanodisc
分子名称: Transient receptor potential cation channel subfamily V member 3
著者Deng, Z, Yuan, P.
登録日2019-11-04
公開日2020-07-01
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (4.33 Å)
主引用文献Gating of human TRPV3 in a lipid bilayer.
Nat.Struct.Mol.Biol., 27, 2020
7K4E
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BU of 7k4e by Molmil
Cryo-EM structure of human TRPV6 in complex with (4- phenylcyclohexyl)piperazine inhibitor 30
分子名称: 5-({4-[(1R,4S)-3'-methyl[1,2,3,4-tetrahydro[1,1'-biphenyl]]-4-yl]piperazin-1-yl}methyl)pyridin-2(1H)-one, Transient receptor potential cation channel subfamily V member 6
著者Neuberger, A, Nadezhdin, K.D, Singh, A.K, Sobolevsky, A.I.
登録日2020-09-15
公開日2020-12-09
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (4.34 Å)
主引用文献Inactivation-mimicking block of the epithelial calcium channel TRPV6.
Sci Adv, 6, 2020
6D7S
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BU of 6d7s by Molmil
Cryo-EM structure of human TRPV6-Y467A in amphipols
分子名称: Transient receptor potential cation channel subfamily V member 6
著者Singh, A.K, Saotome, K, McGoldrick, L.L, Sobolevsky, A.I.
登録日2018-04-25
公開日2018-07-18
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (4.34 Å)
主引用文献Structural bases of TRP channel TRPV6 allosteric modulation by 2-APB.
Nat Commun, 9, 2018
8GKG
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BU of 8gkg by Molmil
Human TRPV3 pentamer structure
分子名称: Transient receptor potential cation channel subfamily V member 3
著者Lansky, S, Betancourt, J.M, Scheuring, S.
登録日2023-03-18
公開日2023-09-06
最終更新日2023-09-20
実験手法ELECTRON MICROSCOPY (4.38 Å)
主引用文献A pentameric TRPV3 channel with a dilated pore.
Nature, 621, 2023
7TW3
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BU of 7tw3 by Molmil
Cryo-EM structure of human ankyrin complex (B2P1A1) from red blood cell
分子名称: Ankyrin-1, Band 3 anion transport protein, Protein 4.2
著者Xia, X, Liu, S.H, Zhou, Z.H.
登録日2022-02-06
公開日2022-06-08
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Structure, dynamics and assembly of the ankyrin complex on human red blood cell membrane.
Nat.Struct.Mol.Biol., 29, 2022
6PVL
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BU of 6pvl by Molmil
Cryo-EM structure of mouse TRPV3 in closed state at 42 degrees Celsius
分子名称: SODIUM ION, Transient receptor potential cation channel subfamily V member 3
著者Singh, A.K, McGoldrick, L.L, Sobolevsky, A.I.
登録日2019-07-21
公開日2019-10-23
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Structural basis of temperature sensation by the TRP channel TRPV3.
Nat.Struct.Mol.Biol., 26, 2019
6DMW
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BU of 6dmw by Molmil
Calmodulin-bound full-length rbTRPV5
分子名称: CALCIUM ION, Calmodulin-1, Transient receptor potential cation channel subfamily V member 5
著者Hughes, T.E.T, Pumroy, R.A, Moiseenkova-Bell, V.Y.
登録日2018-06-05
公開日2018-10-24
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Structural insights on TRPV5 gating by endogenous modulators.
Nat Commun, 9, 2018
6D7T
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BU of 6d7t by Molmil
Cryo-EM structure of human TRPV6-Y467A in complex with 2-Aminoethoxydiphenyl borate (2-APB)
分子名称: 2-aminoethyl diphenylborinate, CALCIUM ION, Transient receptor potential cation channel subfamily V member 6
著者Singh, A.K, Saotome, K, McGoldrick, L.L, Sobolevsky, A.I.
登録日2018-04-25
公開日2018-07-18
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (4.44 Å)
主引用文献Structural bases of TRP channel TRPV6 allosteric modulation by 2-APB.
Nat Commun, 9, 2018
6L93
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BU of 6l93 by Molmil
X-ray structure of the ligand-free human TRPV1 ankyrin repeat domain
分子名称: Transient receptor potential cation channel subfamily V member 1
著者Tanaka, M, Hayakawa, K, Unno, M.
登録日2019-11-08
公開日2020-03-18
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (4.47 Å)
主引用文献Structure determination of the human TRPV1 ankyrin-repeat domain under nonreducing conditions.
Acta Crystallogr.,Sect.F, 76, 2020
6PVP
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BU of 6pvp by Molmil
Cryo-EM structure of mouse TRPV3-Y564A in open state at 37 degrees Celsius
分子名称: SODIUM ION, Transient receptor potential cation channel subfamily V member 3
著者Singh, A.K, McGoldrick, L.L, Sobolevsky, A.I.
登録日2019-07-21
公開日2019-10-23
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (4.48 Å)
主引用文献Structural basis of temperature sensation by the TRP channel TRPV3.
Nat.Struct.Mol.Biol., 26, 2019
6PVM
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BU of 6pvm by Molmil
Cryo-EM structure of mouse TRPV3 in putative sensitized state at 42 degrees Celsius
分子名称: SODIUM ION, Transient receptor potential cation channel subfamily V member 3
著者Singh, A.K, McGoldrick, L.L, Sobolevsky, A.I.
登録日2019-07-21
公開日2019-10-23
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Structural basis of temperature sensation by the TRP channel TRPV3.
Nat.Struct.Mol.Biol., 26, 2019
7PTY
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BU of 7pty by Molmil
Delta-latroinsectotoxin dimer
分子名称: Delta-latroinsectotoxin-Lt1a
著者Chen, M, Gatsogiannis, C.
登録日2021-09-27
公開日2021-12-08
実験手法ELECTRON MICROSCOPY (4.63 Å)
主引用文献Molecular architecture of black widow spider neurotoxins.
Nat Commun, 12, 2021

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件を2024-05-22に公開中

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