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1M3B
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Solution structure of a circular form of the N-terminal SH3 domain (A134C, E135G, R191G mutant) from oncogene protein c-Crk.
Descriptor: Proto-oncogene C-crk
Authors:Schumann, F.H, Varadan, R, Tayakuniyil, P.P, Hall, J.B, Camarero, J.A, Fushman, D.
Deposit date:2002-06-27
Release date:2003-08-05
Last modified:2021-10-27
Method:SOLUTION NMR
Cite:Changing protein backbone topology: Structural and dynamic consequences of the backbone cyclization in SH3 domain
To be Published
1M3A
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BU of 1m3a by Molmil
Solution structure of a circular form of the truncated N-terminal SH3 domain from oncogene protein c-Crk.
Descriptor: Proto-oncogene C-crk
Authors:Schumann, F.H, Varadan, R, Tayakuniyil, P.P, Hall, J.B, Camarero, J.A, Fushman, D.
Deposit date:2002-06-27
Release date:2003-08-05
Last modified:2021-10-27
Method:SOLUTION NMR
Cite:Changing protein backbone topology: Structural and dynamic consequences of the backbone cyclization in SH3 domain
To be Published
1M30
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BU of 1m30 by Molmil
Solution structure of N-terminal SH3 domain from oncogene protein c-Crk
Descriptor: Proto-oncogene C-crk
Authors:Schumann, F.H, Varadan, R, Tayakuniyil, P.P, Hall, J.B, Camarero, J.A, Fushman, D.
Deposit date:2002-06-26
Release date:2003-08-05
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Changing protein backbone topology: Structural and dynamic consequences of the backbone cyclization in SH3 domain
To be Published
1M27
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Crystal structure of SAP/FynSH3/SLAM ternary complex
Descriptor: CITRATE ANION, Proto-oncogene tyrosine-protein kinase FYN, SH2 domain protein 1A, ...
Authors:Chan, B, Griesbach, J, Song, H.K, Poy, F, Terhorst, C, Eck, M.J.
Deposit date:2002-06-21
Release date:2003-05-06
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:SAP couples Fyn to SLAM immune receptors.
NAT.CELL BIOL., 5, 2003
1KSW
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BU of 1ksw by Molmil
Structure of Human c-Src Tyrosine Kinase (Thr338Gly Mutant) in Complex with N6-benzyl ADP
Descriptor: N6-BENZYL ADENOSINE-5'-DIPHOSPHATE, PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC
Authors:Witucki, L.A, Huang, X, Shah, K, Liu, Y, Kyin, S, Eck, M.J, Shokat, K.M.
Deposit date:2002-01-14
Release date:2002-02-27
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Mutant tyrosine kinases with unnatural nucleotide specificity retain the structure and phospho-acceptor specificity of the wild-type enzyme.
Chem.Biol., 9, 2002
1KJW
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SH3-Guanylate Kinase Module from PSD-95
Descriptor: POSTSYNAPTIC DENSITY PROTEIN 95, SULFATE ION
Authors:McGee, A.W, Dakoji, S.R, Olsen, O, Bredt, D.S, Lim, W.A, Prehoda, K.E.
Deposit date:2001-12-05
Release date:2002-01-09
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of the SH3-Guanylate Kinase Module from PSD-95 Suggests a Mechanism for Regulated Assembly of MAGUK Scaffolding Proteins
Mol.Cell, 8, 2001
1KIK
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SH3 Domain of Lymphocyte Specific Kinase (LCK)
Descriptor: PROTO-ONCOGENE TYROSINE-PROTEIN KINASE LCK
Authors:Briese, L, Willbold, D.
Deposit date:2001-12-03
Release date:2001-12-12
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Structure determination of human Lck unique and SH3 domains by nuclear magnetic resonance spectroscopy.
Bmc Struct.Biol., 3, 2003
1KFZ
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BU of 1kfz by Molmil
Solution Structure of C-terminal Sem-5 SH3 Domain (Ensemble of 16 Structures)
Descriptor: SEX MUSCLE ABNORMAL PROTEIN 5
Authors:Ferreon, J.C, Volk, D.E, Luxon, B.A, Gorenstein, D, Hilser, V.J.
Deposit date:2001-11-24
Release date:2003-05-20
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution Structure, Dynamics and Thermodynamics of the Native State Ensemble of Sem-5 C-Terminal SH3 Domain
Biochemistry, 42, 2003
1K9A
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Crystal structure analysis of full-length carboxyl-terminal Src kinase at 2.5 A resolution
Descriptor: Carboxyl-terminal Src kinase
Authors:Ogawa, A, Takayama, Y, Nagata, A, Chong, K.T, Takeuchi, S, Sakai, H, Nakagawa, A, Nada, S, Okada, M, Tsukihara, T.
Deposit date:2001-10-28
Release date:2002-03-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of the carboxyl-terminal Src kinase, Csk.
J.Biol.Chem., 277, 2002
1K76
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Solution Structure of the C-terminal Sem-5 SH3 Domain (Minimized Average Structure)
Descriptor: SEX MUSCLE ABNORMAL PROTEIN 5
Authors:Ferreon, J, Volk, D, Luxon, B, Gorenstein, D, Hilser, V.
Deposit date:2001-10-18
Release date:2003-05-20
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution Structure, Dynamics and Thermodynamics of the Native State Ensemble of Sem-5 C-Terminal SH3 Domain
Biochemistry, 42, 2003
1K4U
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Solution structure of the C-terminal SH3 domain of p67phox complexed with the C-terminal tail region of p47phox
Descriptor: PHAGOCYTE NADPH OXIDASE SUBUNIT P47PHOX, PHAGOCYTE NADPH OXIDASE SUBUNIT P67PHOX
Authors:Kami, K, Takeya, R, Sumimoto, H, Kohda, D.
Deposit date:2001-10-08
Release date:2002-04-08
Last modified:2021-11-10
Method:SOLUTION NMR
Cite:Diverse recognition of non-PxxP peptide ligands by the SH3 domains from p67(phox), Grb2 and Pex13p.
EMBO J., 21, 2002
1K1Z
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BU of 1k1z by Molmil
Solution structure of N-terminal SH3 domain mutant(P33G) of murine Vav
Descriptor: vav
Authors:Ogura, K, Nagata, K, Horiuchi, M, Ebisui, E, Hasuda, T, Yuzawa, S, Nishida, M, Hatanaka, H, Inagaki, F.
Deposit date:2001-09-26
Release date:2001-10-10
Last modified:2021-11-10
Method:SOLUTION NMR
Cite:Solution structure of N-terminal SH3 domain of Vav and the recognition site for Grb2 C-terminal SH3 domain
J.BIOMOL.NMR, 22, 2002
1JXM
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BU of 1jxm by Molmil
CRYSTAL STRUCTURE OF THE GMP BOUND SH3-HOOK-GK FRAGMENT OF PSD-95
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, GUANIDINE, GUANOSINE-5'-MONOPHOSPHATE, ...
Authors:Tavares, G.A, Panepucci, E.H, Brunger, A.T.
Deposit date:2001-09-07
Release date:2002-01-16
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural characterization of the intramolecular interaction between the SH3 and guanylate kinase domains of PSD-95.
Mol.Cell, 8, 2001
1JXO
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Crystal Structure of the SH3-HOOK-GK Fragment of PSD-95
Descriptor: postsynaptic density protein
Authors:Tavares, G.A, Panepucci, E.H, Brunger, A.T.
Deposit date:2001-09-07
Release date:2002-01-16
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural characterization of the intramolecular interaction between the SH3 and guanylate kinase domains of PSD-95.
Mol.Cell, 8, 2001
1GL5
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BU of 1gl5 by Molmil
NMR structure of the SH3 domain from the Tec protein tyrosine kinase
Descriptor: TYROSINE-PROTEIN KINASE TEC
Authors:Mulhern, T.D, Pursglove, S.E, Booker, G.W.
Deposit date:2001-08-28
Release date:2001-11-28
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:The solution structure and intramolecular associations of the Tec kinase SRC homology 3 domain.
J. Biol. Chem., 277, 2002
1JU5
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Ternary complex of an Crk SH2 domain, Crk-derived phophopeptide, and Abl SH3 domain by NMR spectroscopy
Descriptor: Abl, Crk
Authors:Donaldson, L.W, Pawson, T, Kay, L.E, Forman-Kay, J.D.
Deposit date:2001-08-23
Release date:2002-11-06
Last modified:2021-11-10
Method:SOLUTION NMR
Cite:Structure of a regulatory complex involving the Abl SH3 domain, the Crk SH2 domain, and a Crk-derived phosphopeptide
Proc.Natl.Acad.Sci.USA, 99, 2002
1JQQ
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BU of 1jqq by Molmil
Crystal structure of Pex13p(301-386) SH3 domain
Descriptor: PEROXISOMAL MEMBRANE PROTEIN PAS20
Authors:Douangamath, A, Mayans, O, Barnett, P, Distel, B, Wilmanns, M.
Deposit date:2001-08-08
Release date:2002-12-06
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Topography for Independent Binding of alpha-Helical and PPII-Helical Ligands to a Peroxisomal SH3 Domain
Mol.Cell, 10, 2002
1JO8
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BU of 1jo8 by Molmil
Structural analysis of the yeast actin binding protein Abp1 SH3 domain
Descriptor: ACTIN BINDING PROTEIN, SULFATE ION
Authors:Fazi, B, Cope, M.J, Douangamath, A, Ferracuti, S, Schirwitz, K, Zucconi, A, Drubin, D.G, Wilmanns, M, Cesareni, G, Castagnoli, L.
Deposit date:2001-07-27
Release date:2002-03-01
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Unusual binding properties of the SH3 domain of the yeast actin-binding protein Abp1: structural and functional analysis.
J.Biol.Chem., 277, 2002
1JEG
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BU of 1jeg by Molmil
Solution structure of the SH3 domain from C-terminal Src Kinase complexed with a peptide from the tyrosine phosphatase PEP
Descriptor: HEMATOPOIETIC CELL PROTEIN-TYROSINE PHOSPHATASE 70Z-PEP, TYROSINE-PROTEIN KINASE CSK
Authors:Ghose, R, Shekhtman, A, Goger, M.J, Ji, H, Cowburn, D.
Deposit date:2001-06-17
Release date:2001-10-31
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:A novel, specific interaction involving the Csk SH3 domain and its natural ligand.
Nat.Struct.Biol., 8, 2001
1H92
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SH3 domain of human Lck tyrosine kinase
Descriptor: PROTO-ONCOGENE TYROSINE-PROTEIN KINASE LCK
Authors:Schweimer, K, Hoffmann, S, Friedrich, U, Biesinger, B, Roesch, P, Sticht, H.
Deposit date:2001-02-22
Release date:2001-10-22
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structural Investigation of the Binding of a Herpesviral Protein to the SH3 Domain of Tyrosine Kinase Lck
Biochemistry, 41, 2002
1H8K
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A-SPECTRIN SH3 DOMAIN A11V, V23L, M25V, V53I, V58L MUTANT
Descriptor: SPECTRIN ALPHA CHAIN
Authors:Vega, M.C, Serrano, L.
Deposit date:2001-02-09
Release date:2002-05-23
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Conformational Strain in the Hydrophobic Core and its Implications for Protein Folding and Design
Nat.Struct.Biol., 9, 2002
1I07
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EPS8 SH3 DOMAIN INTERTWINED DIMER
Descriptor: EPIDERMAL GROWTH FACTOR RECEPTOR KINASE SUBSTRATE EPS8
Authors:Kishan, K.V.R, Newcomer, M.E.
Deposit date:2001-01-29
Release date:2001-05-09
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Effect of pH and salt bridges on structural assembly: molecular structures of the monomer and intertwined dimer of the Eps8 SH3 domain.
Protein Sci., 10, 2001
1I0C
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BU of 1i0c by Molmil
EPS8 SH3 CLOSED MONOMER
Descriptor: EPIDERMAL GROWTH FACTOR RECEPTOR KINASE SUBSTRATE EPS8
Authors:Kishan, K.V.R, Newcomer, M.E.
Deposit date:2001-01-29
Release date:2001-05-09
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2 Å)
Cite:Effect of pH and salt bridges on structural assembly: molecular structures of the monomer and intertwined dimer of the Eps8 SH3 domain.
Protein Sci., 10, 2001
1IO6
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GROWTH FACTOR RECEPTOR-BOUND PROTEIN 2 (GRB2) C-TERMINAL SH3 DOMAIN COMPLEXED WITH A LIGAND PEPTIDE (NMR, MINIMIZED MEAN STRUCTURE)
Descriptor: A LIGAND PEPTIDE, GROWTH FACTOR RECEPTOR-BOUND PROTEIN 2
Authors:Kawasaki, M, Ogura, K, Hatanaka, H, Inagaki, F.
Deposit date:2001-01-25
Release date:2001-02-14
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Solution Structure of the C-Terminal SH3 Domain of Grb2 Complexed with a Ligand Peptide: A Ligand Exchange Model of the SH3 Domain
To be Published
1G83
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CRYSTAL STRUCTURE OF FYN SH3-SH2
Descriptor: PROTO-ONCOGENE TYROSINE-PROTEIN KINASE FYN
Authors:Arold, S.T, Ulmer, T.S, Mulhern, T.D, Werner, J.M, Ladbury, J.E, Campbell, I.D, Noble, M.E.M.
Deposit date:2000-11-16
Release date:2001-05-30
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The role of the Src homology 3-Src homology 2 interface in the regulation of Src kinases.
J.Biol.Chem., 276, 2001

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