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1AZG	NMR STUDY OF THE SH3 DOMAIN FROM FYN PROTO-ONCOGENE TYROSINE KINASE KINASE COMPLEXED WITH THE SYNTHETIC PEPTIDE P2L CORRESPONDING TO RESIDUES 91-104 OF THE P85 SUBUNIT OF PI3-KINASE, MINIMIZED AVERAGE (PROBMAP) STRUCTURE Descriptor: FYN, PRO-PRO-ARG-PRO-LEU-PRO-VAL-ALA-PRO-GLY-SER-SER-LYS-THR Authors: Renzoni, D.A, Pugh, D.J.R, Siligardi, G, Das, P, Morton, C.J, Rossi, C, Waterfield, M.D, Campbell, I.D, Ladbury, J.E. Deposit date: 1997-11-18 Release date: 1998-02-25 Last modified: 2022-02-16 Method: SOLUTION NMR Cite: Structural and thermodynamic characterization of the interaction of the SH3 domain from Fyn with the proline-rich binding site on the p85 subunit of PI3-kinase. Biochemistry, 35, 1996
1AZE	NMR STRUCTURE OF THE COMPLEX BETWEEN THE C32S-Y7V MUTANT OF THE NSH3 DOMAIN OF GRB2 WITH A PEPTIDE FROM SOS, 10 STRUCTURES Descriptor: GRB2, SOS Authors: Vidal, M, Gincel, E, Goudreau, N, Cornille, F, Parker, F, Duchesne, M, Tocque, B, Garbay, C, Roques, B.P. Deposit date: 1997-11-17 Release date: 1999-05-18 Last modified: 2021-11-03 Method: SOLUTION NMR Cite: Molecular and cellular analysis of Grb2 SH3 domain mutants: interaction with Sos and dynamin. J.Mol.Biol., 290, 1999
1AWO	THE SOLUTION NMR STRUCTURE OF ABL SH3 AND ITS RELATIONSHIP TO SH2 IN THE SH(32) CONSTRUCT, 20 STRUCTURES Descriptor: ABL TYROSINE KINASE Authors: Cowburn, D. Deposit date: 1997-10-03 Release date: 1998-01-28 Last modified: 2022-02-16 Method: SOLUTION NMR Cite: The solution structure of Abl SH3, and its relationship to SH2 in the SH(32) construct. Structure, 3, 1995
1AOJ	THE SH3 DOMAIN OF EPS8 EXISTS AS A NOVEL INTERTWINED DIMER Descriptor: EPS8 Authors: Kishan, K.V.R, Newcomer, M.E. Deposit date: 1997-07-07 Release date: 1998-07-08 Last modified: 2023-08-02 Method: X-RAY DIFFRACTION (2.5 Å) Cite: The SH3 domain of Eps8 exists as a novel intertwined dimer. Nat.Struct.Biol., 4, 1997
1BU1	SRC FAMILY KINASE HCK SH3 DOMAIN Descriptor: PROTEIN (HEMOPOIETIC CELL KINASE) Authors: Arold, S, Franken, P, Dumas, C. Deposit date: 1998-09-09 Release date: 1998-11-11 Last modified: 2023-08-09 Method: X-RAY DIFFRACTION (2.6 Å) Cite: RT loop flexibility enhances the specificity of Src family SH3 domains for HIV-1 Nef. Biochemistry, 37, 1998
1BK2	A-SPECTRIN SH3 DOMAIN D48G MUTANT Descriptor: A-SPECTRIN Authors: Martinez, J.C, Pisabarro, M.T, Serrano, L. Deposit date: 1998-07-14 Release date: 1999-02-16 Last modified: 2023-08-02 Method: X-RAY DIFFRACTION (2.01 Å) Cite: Obligatory steps in protein folding and the conformational diversity of the transition state. Nat.Struct.Biol., 5, 1998
1CSK	THE CRYSTAL STRUCTURE OF HUMAN CSKSH3: STRUCTURAL DIVERSITY NEAR THE RT-SRC AND N-SRC LOOP Descriptor: C-SRC SH3 DOMAIN Authors: Mathieu, M, Wierenga, R.K. Deposit date: 1994-03-22 Release date: 1994-07-31 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.5 Å) Cite: The crystal structure of human CskSH3: structural diversity near the RT-Src and n-Src loop. FEBS Lett., 341, 1994
1CKB	STRUCTURAL BASIS FOR THE SPECIFIC INTERACTION OF LYSINE-CONTAINING PROLINE-RICH PEPTIDES WITH THE N-TERMINAL SH3 DOMAIN OF C-CRK Descriptor: C-CRK N-TERMINAL SH3 DOMAIN, SOS PEPTIDE (PRO-PRO-PRO-VAL-PRO-PRO-ARG-ARG-ARG-ARG) Authors: Wu, X, Kuriyan, J. Deposit date: 1995-01-24 Release date: 1995-05-08 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structural basis for the specific interaction of lysine-containing proline-rich peptides with the N-terminal SH3 domain of c-Crk. Structure, 3, 1995
1CKA	STRUCTURAL BASIS FOR THE SPECIFIC INTERACTION OF LYSINE-CONTAINING PROLINE-RICH PEPTIDES WITH THE N-TERMINAL SH3 DOMAIN OF C-CRK Descriptor: C-CRK N-TERMINAL SH3 DOMAIN, C3G PEPTIDE (PRO-PRO-PRO-ALA-LEU-PRO-PRO-LYS-LYS-ARG) Authors: Wu, X, Kuriyan, J. Deposit date: 1995-01-24 Release date: 1995-05-08 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Structural basis for the specific interaction of lysine-containing proline-rich peptides with the N-terminal SH3 domain of c-Crk. Structure, 3, 1995
5QU6	Crystal Structure of swapped human Nck SH3.1 domain, 1.8A, triclinic Descriptor: Cytoplasmic protein NCK1 Authors: Rudolph, M.G. Deposit date: 2019-12-13 Release date: 2020-02-12 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.816 Å) Cite: Small molecule AX-024 reduces T cell proliferation independently of CD3ε/Nck1 interaction, which is governed by a domain swap in the Nck1-SH3.1 domain. J.Biol.Chem., 295, 2020
5QU8	Crystal Structure of symmetric swapped human Nck SH3.1 domain, 0.93A, orthorhombic form IV Descriptor: Cytoplasmic protein NCK1, SODIUM ION Authors: Rudolph, M.G. Deposit date: 2019-12-13 Release date: 2020-02-12 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (0.93 Å) Cite: Small molecule AX-024 reduces T cell proliferation independently of CD3ε/Nck1 interaction, which is governed by a domain swap in the Nck1-SH3.1 domain. J.Biol.Chem., 295, 2020
5QU3	Crystal Structure of domain swapped human Nck SH3.1, 1.01A, monoclinic Descriptor: Cytoplasmic protein NCK1 Authors: Rudolph, M.G. Deposit date: 2019-12-13 Release date: 2020-02-12 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.02 Å) Cite: Small molecule AX-024 reduces T cell proliferation independently of CD3ε/Nck1 interaction, which is governed by a domain swap in the Nck1-SH3.1 domain. J.Biol.Chem., 295, 2020
5QUA	Crystal Structure of swapped human Nck SH3.1 domain, 1.5A, C2221 Descriptor: Cytoplasmic protein NCK1 Authors: Rudolph, M.G. Deposit date: 2019-12-13 Release date: 2020-02-12 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.51 Å) Cite: Small molecule AX-024 reduces T cell proliferation independently of CD3ε/Nck1 interaction, which is governed by a domain swap in the Nck1-SH3.1 domain. J.Biol.Chem., 295, 2020
5QU1	Crystal Structure of the monomeric human Nck SH3.1 domain, triclinic, 1.08A Descriptor: Cytoplasmic protein NCK1, SULFATE ION Authors: Burger, D, Ruf, A, Benz, J, Schlatter, D, Rudolph, M.G. Deposit date: 2019-12-13 Release date: 2020-02-12 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.08 Å) Cite: Small molecule AX-024 reduces T cell proliferation independently of CD3ε/Nck1 interaction, which is governed by a domain swap in the Nck1-SH3.1 domain. J.Biol.Chem., 295, 2020
5QU5	Domain Swap in the first SH3 domain of human Nck1 Descriptor: Cytoplasmic protein NCK1 Authors: Burger, D, Ruf, A, Benz, J, Schlatter, D, Rudolph, M.G. Deposit date: 2019-12-13 Release date: 2020-02-12 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.11 Å) Cite: Small molecule AX-024 reduces T cell proliferation independently of CD3ε/Nck1 interaction, which is governed by a domain swap in the Nck1-SH3.1 domain. J.Biol.Chem., 295, 2020
5QU2	Crystal Structure of human Nck SH3.1 in complex with peptide PPPVPNPDY Descriptor: ACE-PRO-PRO-PRO-VAL-PRO-ASN-PRO-ASP-TYR-NH2, Cytoplasmic protein NCK1, SULFATE ION Authors: Rudolph, M.G. Deposit date: 2019-12-13 Release date: 2020-02-12 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.04 Å) Cite: Small molecule AX-024 reduces T cell proliferation independently of CD3ε/Nck1 interaction, which is governed by a domain swap in the Nck1-SH3.1 domain. J.Biol.Chem., 295, 2020
5QU7	Crystal Structure of swapped human Nck SH3.1 domain, 1.3A, orthorhombic form III Descriptor: Cytoplasmic protein NCK1 Authors: Rudolph, M.G. Deposit date: 2019-12-13 Release date: 2020-02-12 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.27 Å) Cite: Small molecule AX-024 reduces T cell proliferation independently of CD3ε/Nck1 interaction, which is governed by a domain swap in the Nck1-SH3.1 domain. J.Biol.Chem., 295, 2020
5QU4	Crystal Structure of swapped human Nck SH3.1 domain, 1.05A, orthorhombic form I Descriptor: Cytoplasmic protein NCK1 Authors: Rudolph, M.G. Deposit date: 2019-12-13 Release date: 2020-02-12 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.05 Å) Cite: Small molecule AX-024 reduces T cell proliferation independently of CD3ε/Nck1 interaction, which is governed by a domain swap in the Nck1-SH3.1 domain. J.Biol.Chem., 295, 2020
1E6H	A-SPECTRIN SH3 DOMAIN A11V, M25I, V44I, V58L MUTANTS Descriptor: SPECTRIN ALPHA CHAIN Authors: Vega, M.C, Serrano, L. Deposit date: 2000-08-17 Release date: 2002-05-23 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.01 Å) Cite: Conformational Strain in the Hydrophobic Core and its Implications for Protein Folding and Design Nat.Struct.Biol., 9, 2002
1E6G	A-SPECTRIN SH3 DOMAIN A11V, V23L, M25I, V53I, V58L MUTANT Descriptor: SPECTRIN ALPHA CHAIN, SULFATE ION Authors: Vega, M.C, Serrano, L. Deposit date: 2000-08-15 Release date: 2002-05-23 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Conformational Strain in the Hydrophobic Core and its Implications for Protein Folding and Design Nat.Struct.Biol., 9, 2002
1GCQ	CRYSTAL STRUCTURE OF VAV AND GRB2 SH3 DOMAINS Descriptor: (4R)-2-METHYLPENTANE-2,4-DIOL, GROWTH FACTOR RECEPTOR-BOUND PROTEIN 2, VAV PROTO-ONCOGENE Authors: Nishida, M, Nagata, K, Hachimori, Y, Ogura, K, Inagaki, F. Deposit date: 2000-08-08 Release date: 2001-08-08 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (1.68 Å) Cite: Novel recognition mode between Vav and Grb2 SH3 domains. EMBO J., 20, 2001
1GFD	SOLUTION STRUCTURE AND LIGAND-BINDING SITE OF THE C-TERMINAL SH3 DOMAIN OF GRB2 Descriptor: GROWTH FACTOR RECEPTOR-BOUND PROTEIN 2 Authors: Kohda, D, Terasawa, H, Hatanaka, H, Inagaki, F. Deposit date: 1994-06-13 Release date: 1994-08-31 Last modified: 2024-05-01 Method: SOLUTION NMR Cite: Solution structure and ligand-binding site of the carboxy-terminal SH3 domain of GRB2. Structure, 2, 1994
1GBQ	SOLUTION NMR STRUCTURE OF THE GRB2 N-TERMINAL SH3 DOMAIN COMPLEXED WITH A TEN-RESIDUE PEPTIDE DERIVED FROM SOS DIRECT REFINEMENT AGAINST NOES, J-COUPLINGS, AND 1H AND 13C CHEMICAL SHIFTS, MINIMIZED AVERAGE STRUCTURE Descriptor: GRB2, SOS-1 Authors: Wittekind, M, Mapelli, C, Lee, V, Goldfarb, V, Friedrichs, M.S, Meyers, C.A, Mueller, L. Deposit date: 1996-12-23 Release date: 1997-09-04 Last modified: 2022-02-23 Method: SOLUTION NMR Cite: Solution structure of the Grb2 N-terminal SH3 domain complexed with a ten-residue peptide derived from SOS: direct refinement against NOEs, J-couplings and 1H and 13C chemical shifts. J.Mol.Biol., 267, 1997
1GFC	SOLUTION STRUCTURE AND LIGAND-BINDING SITE OF THE C-TERMINAL SH3 DOMAIN OF GRB2 Descriptor: GROWTH FACTOR RECEPTOR-BOUND PROTEIN 2 Authors: Kohda, D, Terasawa, H, Hatanaka, H, Inagaki, F. Deposit date: 1994-06-13 Release date: 1994-08-31 Last modified: 2024-05-01 Method: SOLUTION NMR Cite: Solution structure and ligand-binding site of the carboxy-terminal SH3 domain of GRB2. Structure, 2, 1994
1G2B	ALPHA-SPECTRIN SRC HOMOLOGY 3 DOMAIN, CIRCULAR PERMUTANT, CUT AT N47-D48 Descriptor: SPECTRIN ALPHA CHAIN, SULFATE ION Authors: Berisio, R, Viguera, A.R, Serrano, L, Wilmanns, M. Deposit date: 2000-10-18 Release date: 2000-11-01 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.12 Å) Cite: Atomic resolution structure of a mutant of the spectrin SH3 domain. Acta Crystallogr.,Sect.D, 57, 2001

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