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3J5Y
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Structure of the mammalian ribosomal pre-termination complex associated with eRF1-eRF3-GDPNP
分子名称: 5'-R(*AP*UP*UP*GP*UP*AP*AP*AP*AP*A)-3', Eukaryotic peptide chain release factor GTP-binding subunit ERF3A, Eukaryotic peptide chain release factor subunit 1, ...
著者des Georges, A, Hashem, Y, Unbehaun, A, Grassucci, R.A, Taylor, D, Hellen, C.U.T, Pestova, T.V, Frank, J.
登録日2013-11-21
公開日2013-12-25
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY (9.7 Å)
主引用文献Structure of the mammalian ribosomal pre-termination complex associated with eRF1*eRF3*GDPNP.
Nucleic Acids Res., 42, 2014
1KK2
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Structure of the large gamma subunit of initiation factor eIF2 from Pyrococcus abyssi-G235D mutant complexed with GDP-Mg2+
分子名称: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ZINC ION, ...
著者Schmitt, E, Blanquet, S, Mechulam, Y.
登録日2001-12-06
公開日2002-04-10
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The large subunit of initiation factor aIF2 is a close structural homologue of elongation factors.
EMBO J., 21, 2002
1KJZ
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Structure of the large gamma subunit of initiation factor eIF2 from Pyrococcus abyssi-G235D mutant
分子名称: ZINC ION, eIF2gamma
著者Schmitt, E, Blanquet, S, Mechulam, Y.
登録日2001-12-06
公開日2002-04-10
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献The large subunit of initiation factor aIF2 is a close structural homologue of elongation factors.
EMBO J., 21, 2002
1KK1
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Structure of the large gamma subunit of initiation factor eIF2 from Pyrococcus abyssi-G235D mutant complexed with GDPNP-Mg2+
分子名称: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ZINC ION, ...
著者Schmitt, E, Blanquet, S, Mechulam, Y.
登録日2001-12-06
公開日2002-04-10
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The large subunit of initiation factor aIF2 is a close structural homologue of elongation factors.
EMBO J., 21, 2002
1KTV
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Crystal Structure of Elongation Factor G Dimer Without Nucleotide
分子名称: ELONGATION FACTOR G
著者Laurberg, M, Kristensen, O, Su, X.D, Liljas, A.
登録日2002-01-17
公開日2003-12-23
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献A New Crystal Form of Thermus thermophilus Elongation Factor G Indicates Crystallographic Limitations Imposed on Molecular Flexibility
To be Published
2C77
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EF-Tu complexed with a GTP analog and the antibiotic GE2270 A
分子名称: DI(HYDROXYETHYL)ETHER, ELONGATION FACTOR TU-B, MAGNESIUM ION, ...
著者Parmeggiani, A, Krab, I.M, Okamura, S, Nielsen, R.C, Nyborg, J, Nissen, P.
登録日2005-11-18
公開日2006-03-16
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural basis of the action of pulvomycin and GE2270 A on elongation factor Tu.
Biochemistry, 45, 2006
2C78
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EF-Tu complexed with a GTP analog and the antibiotic pulvomycin
分子名称: (1S,2S,3E,5E,7E,10S,11S,12S)-12-[(2R,4E,6E,8Z,10R,12E,14E,16Z,18S,19Z)-10,18-DIHYDROXY-12,16,19-TRIMETHYL-11,22-DIOXOOX ACYCLODOCOSA-4,6,8,12,14,16,19-HEPTAEN-2-YL]-2,11-DIHYDROXY-1,10-DIMETHYL-9-OXOTRIDECA-3,5,7-TRIEN-1-YL 6-DEOXY-2,4-DI-O-METHYL-BETA-L-GALACTOPYRANOSIDE, ELONGATION FACTOR TU-A, MAGNESIUM ION, ...
著者Parmeggiani, A, Krab, I.M, Okamura, S, Nielsen, R.C, Nyborg, J, Nissen, P.
登録日2005-11-18
公開日2006-03-16
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structural basis of the action of pulvomycin and GE2270 A on elongation factor Tu.
Biochemistry, 45, 2006
2D74
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Crystal structure of translation initiation factor aIF2betagamma heterodimer
分子名称: Translation initiation factor 2 beta subunit, Translation initiation factor 2 gamma subunit, ZINC ION
著者Sokabe, M, Yao, M, Sakai, N, Toya, S, Tanaka, I.
登録日2005-11-16
公開日2006-07-25
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of archaeal translational initiation factor 2 betagamma-GDP reveals significant conformational change of the beta-subunit and switch 1 region.
Proc.Natl.Acad.Sci.USA, 103, 2006
2DCU
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Crystal structure of translation initiation factor aIF2betagamma heterodimer with GDP
分子名称: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Translation initiation factor 2 beta subunit, ...
著者Sokabe, M, Yao, M, Sakai, N, Toya, S, Tanaka, I.
登録日2006-01-16
公開日2006-07-25
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Structure of archaeal translational initiation factor 2 betagamma-GDP reveals significant conformational change of the beta-subunit and switch 1 region.
Proc.Natl.Acad.Sci.USA, 103, 2006
1LS2
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Fitting of EF-Tu and tRNA in the Low Resolution Cryo-EM Map of an EF-Tu Ternary Complex (GDP and Kirromycin) Bound to E. coli 70S Ribosome
分子名称: Elongation Factor Tu, Phenylalanine transfer RNA
著者Valle, M, Sengupta, J, Swami, N.K, Grassucci, R.A, Burkhardt, N, Nierhaus, K.H, Agrawal, R.K, Frank, J.
登録日2002-05-16
公開日2002-06-26
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (16.799999 Å)
主引用文献Cryo-EM reveals an active role for aminoacyl-tRNA in the accommodation process.
EMBO J., 21, 2002
2DY1
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Crystal structure of EF-G-2 from Thermus thermophilus
分子名称: Elongation factor G, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION
著者Wang, H, Takemoto, C, Murayama, K, Terada, T, Chen, L, Liu, Z.J, Wang, B.C, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2006-09-04
公開日2007-09-25
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal structure of EF-G-2 from Thermus thermophilus
To be Published
1MJ1
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FITTING THE TERNARY COMPLEX OF EF-Tu/tRNA/GTP AND RIBOSOMAL PROTEINS INTO A 13 A CRYO-EM MAP OF THE COLI 70S RIBOSOME
分子名称: Elongation Factor Tu, L11 ribosomal protein, Phe-tRNA, ...
著者Stark, H, Rodnina, M.V, Wieden, H.-J, Zemlin, F, Wintermeyer, W, Vanheel, M.
登録日2002-08-26
公開日2002-11-01
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (13 Å)
主引用文献Ribosome Interactions of Aminoacyl-tRNA and Elongation Factor TU in the Codon Recognition Complex
Nat.Struct.Biol., 9, 2002
2EFG
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TRANSLATIONAL ELONGATION FACTOR G COMPLEXED WITH GDP
分子名称: GUANOSINE-5'-DIPHOSPHATE, PROTEIN (ELONGATION FACTOR G DOMAIN 3), PROTEIN (ELONGATION FACTOR G)
著者Czworkowski, J, Wang, J, Steitz, T.A, Moore, P.B.
登録日1998-09-23
公開日1999-09-30
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献The crystal structure of elongation factor G complexed with GDP, at 2.7 A resolution.
EMBO J., 13, 1994
2E1R
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Structure of eEF2 in complex with a sordarin derivative
分子名称: (1S,4S,5S,6R,9S,11S)-6-CHLORO-9-FORMYL-13-ISOPROPYL-5-METHYL-2-({[(3AR,5R,7R ,7AS)-7-METHYL-3-METHYLENEHEXAHYDRO-2H-FURO[2,3-C]PYRAN-5-YL]OXY}METHYL)TETR ACYCLO[7.4.0.02,11.04,8]TRIDEC-12-ENE-1-CARBOXYLIC ACI, Elongation factor 2, GUANOSINE-5'-DIPHOSPHATE
著者Soe, R, Mosley, R.T, Andersen, G.R.
登録日2006-10-27
公開日2006-11-14
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献Sordarin derivatives induce a novel conformation of the yeast ribosome translocation factor eEF2
J.Biol.Chem., 282, 2007
1N0V
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Crystal structure of elongation factor 2
分子名称: Elongation factor 2
著者Joergensen, R, Ortiz, P.A, Carr-Schmid, A, Nissen, P, Kinzy, T.G, Andersen, G.R.
登録日2002-10-15
公開日2002-11-27
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Two crystal structures demonstrate large conformational changes in the eukaryotic ribosomal translocase.
Nat.Struct.Biol., 10, 2003
1N0U
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Crystal structure of yeast elongation factor 2 in complex with sordarin
分子名称: Elongation factor 2, [1R-(1.ALPHA.,3A.BETA.,4.BETA.,4A.BETA.,7.BETA.,7A.ALPHA.,8A.BETA.)]8A-[(6-DEOXY-4-O-METHYL-BETA-D-ALTROPYRANOSYLOXY)METHYL]-4-FORMYL-4,4A,5,6,7,7A,8,8A-OCTAHYDRO-7-METHYL-3-(1-METHYLETHYL)-1,4-METHANO-S-INDACENE-3A(1H)-CARBOXYLIC ACID
著者Joergensen, R, Ortiz, P.A, Carr-Schmid, A, Nissen, P, Kinzy, T.G, Andersen, G.R.
登録日2002-10-15
公開日2003-02-11
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.12 Å)
主引用文献Two crystal structures demonstrate large conformational changes in the eukaryotic ribosomal translocase.
Nat. Struct. Biol., 10, 2003
1OB2
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E. coli elongation factor EF-Tu complexed with the antibiotic kirromycin, a GTP analog, and Phe-tRNA
分子名称: ELONGATION FACTOR TU, KIRROMYCIN, MAGNESIUM ION, ...
著者Kristensen, O, Nissen, P, Nyborg, J.
登録日2003-01-24
公開日2004-05-27
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (3.35 Å)
主引用文献Kirromycin Defines a Specific Domain Arrangement of Elongation Factor EF-TU
To be Published
1OB5
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T. aquaticus elongation factor EF-Tu complexed with the antibiotic enacyloxin IIa, a GTP analog, and Phe-tRNA
分子名称: ELONGATION FACTOR TU, ENACYLOXIN IIA, MAGNESIUM ION, ...
著者Dahlberg, C, Nielsen, R.C, Parmeggiani, A, Nyborg, J, Nissen, P.
登録日2003-01-24
公開日2005-10-13
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Enacyloxin Iia Pinpoints a Binding Pocket of Elongation Factor TU for Development of Novel Antibiotics.
J.Biol.Chem., 281, 2006
2FX3
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Crystal Structure Determination of E. coli Elongation Factor, Tu using a Twinned Data Set
分子名称: Elongation factor Tu, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
著者Heffron, S.E, Moeller, R, Jurnak, F.
登録日2006-02-03
公開日2006-03-28
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Solving the structure of Escherichia coli elongation factor Tu using a twinned data set.
Acta Crystallogr.,Sect.D, 62, 2006
2H5E
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Crystal structure of E.coli polypeptide release factor RF3
分子名称: GUANOSINE-5'-DIPHOSPHATE, Peptide chain release factor RF-3
著者Song, H.W, Zhou, Z.H.
登録日2006-05-26
公開日2007-05-15
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献RF3 induces ribosomal conformational changes responsible for dissociation of class I release factors
Cell(Cambridge,Mass.), 129, 2007
2HDN
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Trypsin-modified Elongation Factor Tu in complex with tetracycline at 2.8 Angstrom resolution
分子名称: Elongation factor EF-Tu, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
著者Mui, S, Heffron, S.E, Aorora, A, Abel, K, Bergmann, E, Jurnak, F.
登録日2006-06-20
公開日2006-10-31
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Molecular complementarity between tetracycline and the GTPase active site of elongation factor Tu.
Acta Crystallogr.,Sect.D, 62, 2006
2HCJ
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Trypsin-modified Elongation Factor Tu in complex with tetracycline
分子名称: GLYOXYLIC ACID, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
著者Mui, S, Heffron, S.E, Aorora, A, Abel, K, Bergmann, E, Jurnak, F.
登録日2006-06-16
公開日2006-10-31
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.12 Å)
主引用文献Molecular complementarity between tetracycline and the GTPase active site of elongation factor Tu.
Acta Crystallogr.,Sect.D, 62, 2006
1PN6
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Domain-wise fitting of the crystal structure of T.thermophilus EF-G into the low resolution map of the release complex.Puromycin.EFG.GDPNP of E.coli 70S ribosome.
分子名称: Elongation factor G
著者Valle, M, Zavialov, A, Sengupta, J, Rawat, U, Ehrenberg, M, Frank, J.
登録日2003-06-12
公開日2003-07-15
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (10.8 Å)
主引用文献Locking and Unlocking of Ribosomal Motions
Cell(Cambridge,Mass.), 114, 2003
5A9X
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Structure of GDP bound BipA
分子名称: GTP-BINDING PROTEIN, GUANOSINE-5'-DIPHOSPHATE
著者Kumar, V, Chen, Y, Ero, R, Li, Z, Gao, Y.-G.
登録日2015-07-23
公開日2015-08-26
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献Structure of Bipa in GTP Form Bound to the Ratcheted Ribosome.
Proc.Natl.Acad.Sci.USA, 112, 2015
4ZU9
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Crystal structure of bacterial selenocysteine-specific elongation factor EF-Sec
分子名称: CYSTEINE, Elongation factor SelB, MAGNESIUM ION, ...
著者Itoh, Y, Sekine, S, Yokoyama, S.
登録日2015-05-15
公開日2015-09-23
最終更新日2020-02-19
実験手法X-RAY DIFFRACTION (3.191 Å)
主引用文献Crystal structure of the full-length bacterial selenocysteine-specific elongation factor SelB
Nucleic Acids Res., 43, 2015

220113

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