6PZ9
 
 | | Cryo-EM structure of the pancreatic beta-cell SUR1 bound to ATP and repaglinide | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ATP-sensitive inward rectifier potassium channel 11, ... | | 著者 | Shyng, S.L, Yoshioka, C, Martin, G.M, Sung, M.W. | | 登録日 | 2019-07-31 | | 公開日 | 2019-08-14 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (3.65 Å) | | 主引用文献 | Mechanism of pharmacochaperoning in a mammalian K ATP channel revealed by cryo-EM.
Elife, 8, 2019
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6PZC
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6MBN
 | | LptB E163Q in complex with ATP | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, GLYCEROL, Lipopolysaccharide export system ATP-binding protein LptB, ... | | 著者 | Owens, T.W, Ruiz, N, Kahne, D. | | 登録日 | 2018-08-30 | | 公開日 | 2019-08-14 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.957 Å) | | 主引用文献 | Combining Mutations That Inhibit Two Distinct Steps of the ATP Hydrolysis Cycle Restores Wild-Type Function in the Lipopolysaccharide Transporter and Shows that ATP Binding Triggers Transport.
Mbio, 10, 2019
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6JBJ
 | | Cryo-EM structure of human lysosomal cobalamin exporter ABCD4 | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family D member 4 | | 著者 | Xu, D, Feng, Z, Hou, W.T, Jiang, Y.L, Wang, L, Sun, L.F, Zhou, C.Z, Chen, Y. | | 登録日 | 2019-01-25 | | 公開日 | 2019-09-11 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Cryo-EM structure of human lysosomal cobalamin exporter ABCD4.
Cell Res., 29, 2019
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6MGF
 | | untagged, wild-type LptB in complex with ADP | | 分子名称: | (3s,5s,7s)-N-{7-[(3-O-carbamoyl-6-deoxy-5-methyl-4-O-methyl-beta-D-gulopyranosyl)oxy]-4-hydroxy-8-methyl-2-oxo-2H-1-ben zopyran-3-yl}tricyclo[3.3.1.1~3,7~]decane-1-carboxamide, ADENOSINE-5'-DIPHOSPHATE, Lipopolysaccharide export system ATP-binding protein LptB, ... | | 著者 | Mandler, M.D, Owens, T.W, Ruiz, N, Kahne, D. | | 登録日 | 2018-09-13 | | 公開日 | 2019-09-18 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.982 Å) | | 主引用文献 | Bypassing the requirement for coupling of ATP binding and hydrolysis in the lipopolysaccharide ABC transporte
not published
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6S8N
 | | Cryo-EM structure of LptB2FGC in complex with lipopolysaccharide | | 分子名称: | 2-decyl-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione, DODECYL-BETA-D-MALTOSIDE, Inner membrane protein yjgQ, ... | | 著者 | Tang, X.D, Chang, S.H, Luo, Q.H, Zhang, Z.Y, Qiao, W, Xu, C.H, Zhang, C.B, Niu, Y, Yang, W.X, Wang, T, Zhang, Z.B, Zhu, X.F, Dong, C.J, Zhang, X, Dong, H.H. | | 登録日 | 2019-07-10 | | 公開日 | 2019-09-25 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Cryo-EM structures of lipopolysaccharide transporter LptB2FGC in lipopolysaccharide or AMP-PNP-bound states reveal its transport mechanism.
Nat Commun, 10, 2019
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6S8H
 | | Cryo-EM structure of LptB2FG in complex with LPS | | 分子名称: | (2~{R},4~{R},5~{R},6~{R})-6-[(1~{R})-1,2-bis(oxidanyl)ethyl]-2-[(2~{R},4~{R},5~{R},6~{R})-6-[(1~{R})-1,2-bis(oxidanyl)ethyl]-5-[(2~{S},3~{S},4~{R},5~{R},6~{R})-6-[(1~{S})-1,2-bis(oxidanyl)ethyl]-4-[(2~{R},3~{S},4~{R},5~{S},6~{R})-6-[(1~{S})-2-[(2~{S},3~{S},4~{S},5~{S},6~{R})-6-[(1~{S})-1,2-bis(oxidanyl)ethyl]-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-1-oxidanyl-ethyl]-3,4-bis(oxidanyl)-5-phosphonooxy-oxan-2-yl]oxy-3-oxidanyl-5-phosphonooxy-oxan-2-yl]oxy-2-carboxy-2-[[(2~{R},3~{S},4~{R},5~{R},6~{R})-5-[[(3~{R})-3-dodecanoyloxytetradecanoyl]amino]-6-[[(2~{R},3~{S},4~{R},5~{R},6~{R})-3-oxidanyl-5-[[(3~{R})-3-oxidanyltetradecanoyl]amino]-4-[(3~{R})-3-oxidanyltetradecanoyl]oxy-6-phosphonooxy-oxan-2-yl]methoxy]-3-phosphonooxy-4-[(3~{R})-3-tetradecanoyloxytetradecanoyl]oxy-oxan-2-yl]methoxy]oxan-4-yl]oxy-4,5-bis(oxidanyl)oxane-2-carboxylic acid, 2-decyl-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione, DODECYL-BETA-D-MALTOSIDE, ... | | 著者 | Tang, X.D, Chang, S.H, Luo, Q.H, Zhang, Z.Y, Qiao, W, Xu, C.H, Zhang, C.B, Niu, Y, Yang, W.X, Wang, T, Zhang, Z.B, Zhu, X.F, Dong, C.J, Zhang, X, Dong, H.H. | | 登録日 | 2019-07-10 | | 公開日 | 2019-09-25 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Cryo-EM structures of lipopolysaccharide transporter LptB2FGC in lipopolysaccharide or AMP-PNP-bound states reveal its transport mechanism.
Nat Commun, 10, 2019
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6S8G
 | | Cryo-EM structure of LptB2FGC in complex with AMP-PNP | | 分子名称: | Inner membrane protein yjgQ, LPS export ABC transporter permease LptF, Lipopolysaccharide ABC transporter, ... | | 著者 | Tang, X.D, Chang, S.H, Luo, Q.H, Zhang, Z.Y, Qiao, W, Xu, C.H, Zhang, C.B, Niu, Y, Yang, W.X, Wang, T, Zhang, Z.B, Zhu, X.F, Dong, C.J, Zhang, X, Dong, H.H. | | 登録日 | 2019-07-10 | | 公開日 | 2019-09-25 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Cryo-EM structures of lipopolysaccharide transporter LptB2FGC in lipopolysaccharide or AMP-PNP-bound states reveal its transport mechanism.
Nat Commun, 10, 2019
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6S7P
 | | Nucleotide bound ABCB4 | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, CHOLESTEROL, MAGNESIUM ION, ... | | 著者 | Olsen, J.A, Alam, A, Kowal, J, Stieger, B, Locher, K.P. | | 登録日 | 2019-07-05 | | 公開日 | 2019-12-25 | | 最終更新日 | 2020-01-22 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structure of the human lipid exporter ABCB4 in a lipid environment.
Nat.Struct.Mol.Biol., 27, 2020
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6NLO
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6V9Z
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6TMF
 | | Structure of an archaeal ABCE1-bound ribosomal post-splitting complex | | 分子名称: | 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | | 著者 | Kratzat, H, Becker, T, Tampe, R, Beckmann, R. | | 登録日 | 2019-12-04 | | 公開日 | 2020-02-12 | | 最終更新日 | 2020-05-13 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Molecular analysis of the ribosome recycling factor ABCE1 bound to the 30S post-splitting complex.
Embo J., 39, 2020
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6P6J
 | | Structure of YbtPQ importer with substrate Ybt-Fe bound | | 分子名称: | ABC transporter protein, FE (III) ION, inner membrane ABC-transporter, ... | | 著者 | Wang, Z, Hu, W, Zheng, H. | | 登録日 | 2019-06-04 | | 公開日 | 2020-03-04 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Pathogenic siderophore ABC importer YbtPQ adopts a surprising fold of exporter.
Sci Adv, 6, 2020
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6P6I
 | | Structure of YbtPQ importer | | 分子名称: | ABC transporter protein, inner membrane ABC-transporter | | 著者 | Wang, Z, Hu, W, Zheng, H. | | 登録日 | 2019-06-04 | | 公開日 | 2020-03-04 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (3.67 Å) | | 主引用文献 | Pathogenic siderophore ABC importer YbtPQ adopts a surprising fold of exporter.
Sci Adv, 6, 2020
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6UZL
 | | Cryo-EM structure of nucleotide-free MsbA reconstituted into peptidiscs, conformation 2 | | 分子名称: | Lipid A export ATP-binding/permease protein MsbA | | 著者 | Angiulli, G, Walz, T, Dhupar, H.S, Suzuki, H, Wason, I.S, Duong Van Hoa, F. | | 登録日 | 2019-11-15 | | 公開日 | 2020-03-04 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | | 主引用文献 | New approach for membrane protein reconstitution into peptidiscs and basis for their adaptability to different proteins.
Elife, 9, 2020
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6UZ2
 | | Cryo-EM structure of nucleotide-free MsbA reconstituted into peptidiscs, conformation 1 | | 分子名称: | Lipid A export ATP-binding/permease protein MsbA | | 著者 | Angiulli, G, Walz, T, Dhupar, H.S, Suzuki, H, Wason, I.S, Duong Van Hoa, F. | | 登録日 | 2019-11-14 | | 公開日 | 2020-03-04 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | New approach for membrane protein reconstitution into peptidiscs and basis for their adaptability to different proteins.
Elife, 9, 2020
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6TQF
 | | The structure of ABC transporter Rv1819c in AMP-PNP bound state | | 分子名称: | ABC transporter ATP-binding protein/permease, DODECYL-BETA-D-MALTOSIDE, MAGNESIUM ION, ... | | 著者 | Rempel, S, Gati, C, Slotboom, D.J, Guskov, A. | | 登録日 | 2019-12-16 | | 公開日 | 2020-04-01 | | 最終更新日 | 2021-02-10 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | A mycobacterial ABC transporter mediates the uptake of hydrophilic compounds.
Nature, 580, 2020
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6TEJ
 | | Structure of apo IrtAB devoid SID in complex with sybody Syb_NL5 | | 分子名称: | DECYL-BETA-D-MALTOPYRANOSIDE, Drug ABC transporter ATP-binding protein, NICKEL (II) ION, ... | | 著者 | Gonda, I, Arnold, F.M, Hutter, C.A.J, Weber, M.S, Seeger, M.A, Hurlimann, L.M. | | 登録日 | 2019-11-12 | | 公開日 | 2020-04-01 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | The ABC exporter IrtAB imports and reduces mycobacterial siderophores.
Nature, 580, 2020
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6TQE
 | | The structure of ABC transporter Rv1819c without addition of substrate | | 分子名称: | ABC transporter ATP-binding protein/permease, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION | | 著者 | Rempel, S, Gati, C, Slotboom, D.J, Guskov, A. | | 登録日 | 2019-12-16 | | 公開日 | 2020-04-01 | | 最終更新日 | 2021-02-10 | | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | | 主引用文献 | A mycobacterial ABC transporter mediates the uptake of hydrophilic compounds.
Nature, 580, 2020
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6YAL
 | | Mammalian 48S late-stage initiation complex with beta-globin mRNA | | 分子名称: | 18S ribosomal RNA, 40S Ribosomal protein uS3, 40S Ribosomal protein uS7, ... | | 著者 | Bochler, A, Simonetti, A, Guca, E, Hashem, Y. | | 登録日 | 2020-03-12 | | 公開日 | 2020-04-08 | | 最終更新日 | 2020-04-22 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Structural Insights into the Mammalian Late-Stage Initiation Complexes.
Cell Rep, 31, 2020
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6LR0
 | | structure of human bile salt exporter ABCB11 | | 分子名称: | Bile salt export pump | | 著者 | Wang, L, Hou, W.T, Chen, L, Jiang, Y.L, Xu, D, Sun, L.F, Zhou, C.Z, Chen, Y. | | 登録日 | 2020-01-15 | | 公開日 | 2020-04-15 | | 最終更新日 | 2023-01-18 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Cryo-EM structure of human bile salts exporter ABCB11.
Cell Res., 30, 2020
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6R72
 | | Crystal structure of BmrA-E504A in an outward-facing conformation | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Multidrug exporter ATP-binding cassette | | 著者 | Chaptal, V, Zampieri, V, Kilburg, A, Magnard, S, Falson, P. | | 登録日 | 2019-03-28 | | 公開日 | 2020-05-06 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (3.95 Å) | | 主引用文献 | Substrate-bound and substrate-free outward-facing structures of a multidrug ABC exporter.
Sci Adv, 8, 2022
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6R81
 | | Multidrug resistance transporter BmrA mutant E504A bound with ATP and Mg solved by Cryo-EM | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Lipid A export ATP-binding/permease protein MsbA, MAGNESIUM ION | | 著者 | Wiseman, B, Chaptal, V, Zampieri, V, Magnard, S, Hogbom, M, Falson, P. | | 登録日 | 2019-03-30 | | 公開日 | 2020-05-06 | | 最終更新日 | 2022-02-02 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Substrate-bound and substrate-free outward-facing structures of a multidrug ABC exporter.
Sci Adv, 8, 2022
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6VXF
 | | Structure of apo-closed ABCG2 | | 分子名称: | Broad substrate specificity ATP-binding cassette transporter ABCG2 | | 著者 | Orlando, B.J, Maofu, L. | | 登録日 | 2020-02-21 | | 公開日 | 2020-05-13 | | 最終更新日 | 2020-05-20 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | ABCG2 transports anticancer drugs via a closed-to-open switch.
Nat Commun, 11, 2020
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6VXJ
 | | Structure of ABCG2 bound to SN38 | | 分子名称: | 7-ethyl-10-hydroxycamptothecin, Broad substrate specificity ATP-binding cassette transporter ABCG2, CHOLESTEROL | | 著者 | Orlando, B.J, Liao, M. | | 登録日 | 2020-02-22 | | 公開日 | 2020-05-13 | | 最終更新日 | 2020-05-20 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | ABCG2 transports anticancer drugs via a closed-to-open switch.
Nat Commun, 11, 2020
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