6HS3
 
 | |
6HBU
 | | Cryo-EM structure of the ABCG2 E211Q mutant bound to ATP and Magnesium | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family G member 2, MAGNESIUM ION | | 著者 | Manolaridis, I, Jackson, S.M, Taylor, N.M.I, Kowal, J, Stahlberg, H, Locher, K.P. | | 登録日 | 2018-08-13 | | 公開日 | 2018-11-07 | | 最終更新日 | 2019-10-23 | | 実験手法 | ELECTRON MICROSCOPY (3.09 Å) | | 主引用文献 | Cryo-EM structures of a human ABCG2 mutant trapped in ATP-bound and substrate-bound states.
Nature, 563, 2018
|
|
6HCO
 | | Cryo-EM structure of the ABCG2 E211Q mutant bound to estrone 3-sulfate and 5D3-Fab | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5D3-Fab heavy chain, 5D3-Fab light chain, ... | | 著者 | Manolaridis, I, Jackson, S.M, Taylor, N.M.I, Kowal, J, Stahlberg, H, Locher, K.P. | | 登録日 | 2018-08-15 | | 公開日 | 2018-11-07 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (3.58 Å) | | 主引用文献 | Cryo-EM structures of a human ABCG2 mutant trapped in ATP-bound and substrate-bound states.
Nature, 563, 2018
|
|
6CVL
 | | Crystal structure of the Escherichia coli ATPgS-bound MetNI methionine ABC transporter in complex with its MetQ binding protein | | 分子名称: | IODIDE ION, MERCURY (II) ION, MetI transmembrane subunit, ... | | 著者 | Nguyen, P.T, Kaiser, J.T, Rees, D.C. | | 登録日 | 2018-03-28 | | 公開日 | 2018-11-14 | | 最終更新日 | 2022-04-27 | | 実験手法 | X-RAY DIFFRACTION (2.953 Å) | | 主引用文献 | Noncanonical role for the binding protein in substrate uptake by the MetNI methionine ATP Binding Cassette (ABC) transporter.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
|
|
6HZM
 | | Cryo-EM structure of the ABCG2 E211Q mutant bound to ATP and Magnesium (alternative placement of Magnesium into the cryo-EM density) | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family G member 2, MAGNESIUM ION | | 著者 | Manolaridis, I, Jackson, S.M, Taylor, N.M.I, Kowal, J, Stahlberg, H, Locher, K.P. | | 登録日 | 2018-10-23 | | 公開日 | 2018-11-14 | | 最終更新日 | 2019-12-18 | | 実験手法 | ELECTRON MICROSCOPY (3.09 Å) | | 主引用文献 | Cryo-EM structures of a human ABCG2 mutant trapped in ATP-bound and substrate-bound states.
Nature, 563, 2018
|
|
6MSM
 | | Phosphorylated, ATP-bound human cystic fibrosis transmembrane conductance regulator (CFTR) | | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, ADENOSINE-5'-TRIPHOSPHATE, CHOLESTEROL, ... | | 著者 | Zhang, Z, Liu, F, Chen, J. | | 登録日 | 2018-10-16 | | 公開日 | 2018-11-21 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Molecular structure of the ATP-bound, phosphorylated human CFTR.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
|
|
6Q81
 | | Structure of P-glycoprotein(ABCB1) in the post-hydrolytic state | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, P-glycoprotein (ABCB1) | | 著者 | Ford, R.C, Thonghin, N, Collins, R.F, Barbieri, A, Shafi, T, Siebert, A. | | 登録日 | 2018-12-13 | | 公開日 | 2018-12-26 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (7.9 Å) | | 主引用文献 | Novel features in the structure of P-glycoprotein (ABCB1) in the post-hydrolytic state as determined at 7.9 angstrom resolution.
Bmc Struct.Biol., 18, 2018
|
|
6BL6
 | | Crystallization of lipid A transporter MsbA from Salmonella typhimurium | | 分子名称: | Lipid A export ATP-binding/permease protein MsbA | | 著者 | Padayatti, P.S, Stanfield, R.L, Zhang, Q, Wilson, I.A, Lee, S.C. | | 登録日 | 2017-11-09 | | 公開日 | 2019-01-09 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structural Insights into the Lipid A Transport Pathway in MsbA.
Structure, 27, 2019
|
|
6A6N
 | | Crystal structure of an inward-open apo state of the eukaryotic ABC multidrug transporter CmABCB1 | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ATP-binding cassette, sub-family B, ... | | 著者 | Kato, H, Nakatsu, T, Kodan, A. | | 登録日 | 2018-06-28 | | 公開日 | 2019-01-16 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.02 Å) | | 主引用文献 | Inward- and outward-facing X-ray crystal structures of homodimeric P-glycoprotein CmABCB1.
Nat Commun, 10, 2019
|
|
6IC4
 | |
6BZR
 | |
6A6M
 | | Crystal structure of an outward-open nucleotide-bound state of the eukaryotic ABC multidrug transporter CmABCB1 | | 分子名称: | ATP-binding cassette, sub-family B, member 1, ... | | 著者 | Kato, H, Nakatsu, T, Kodan, A. | | 登録日 | 2018-06-28 | | 公開日 | 2019-02-20 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Inward- and outward-facing X-ray crystal structures of homodimeric P-glycoprotein CmABCB1.
Nat Commun, 10, 2019
|
|
6QEX
 | |
6HRC
 | | Outward-facing PglK with ATPgammaS bound | | 分子名称: | MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, WlaB protein | | 著者 | Perez, C, Locher, K.P. | | 登録日 | 2018-09-26 | | 公開日 | 2019-03-06 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Structure of Outward-Facing PglK and Molecular Dynamics of Lipid-Linked Oligosaccharide Recognition and Translocation.
Structure, 27, 2019
|
|
6M96
 | |
6MJP
 | | LptB(E163Q)FGC from Vibrio cholerae | | 分子名称: | 2-(2-ETHOXYETHOXY)ETHANOL, 6-cyclohexylhexyl beta-D-glucopyranoside, ABC transporter ATP-binding protein, ... | | 著者 | Owens, T.W, Kahne, D, Kruse, A.C. | | 登録日 | 2018-09-21 | | 公開日 | 2019-03-27 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | Structural basis of unidirectional export of lipopolysaccharide to the cell surface.
Nature, 567, 2019
|
|
6MIT
 | | LptBFGC from Enterobacter cloacae | | 分子名称: | CHLORIDE ION, LPS export ABC transporter permease LptF, Lipopolysaccharide export system ATP-binding protein, ... | | 著者 | Owens, T.W, Kahne, D, Kruse, A.C. | | 登録日 | 2018-09-20 | | 公開日 | 2019-03-27 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Structural basis of unidirectional export of lipopolysaccharide to the cell surface.
Nature, 567, 2019
|
|
6MHU
 | | Nucleotide-free Cryo-EM Structure of E.coli LptB2FG Transporter | | 分子名称: | (2~{R},4~{R},5~{R},6~{R})-6-[(1~{R})-1,2-bis(oxidanyl)ethyl]-2-[(2~{R},4~{R},5~{R},6~{R})-6-[(1~{R})-1,2-bis(oxidanyl)ethyl]-5-[(2~{S},3~{S},4~{R},5~{R},6~{R})-6-[(1~{S})-1,2-bis(oxidanyl)ethyl]-4-[(2~{R},3~{S},4~{R},5~{S},6~{R})-6-[(1~{S})-2-[(2~{S},3~{S},4~{S},5~{S},6~{R})-6-[(1~{S})-1,2-bis(oxidanyl)ethyl]-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-1-oxidanyl-ethyl]-3,4-bis(oxidanyl)-5-phosphonooxy-oxan-2-yl]oxy-3-oxidanyl-5-phosphonooxy-oxan-2-yl]oxy-2-carboxy-2-[[(2~{R},3~{S},4~{R},5~{R},6~{R})-5-[[(3~{R})-3-dodecanoyloxytetradecanoyl]amino]-6-[[(2~{R},3~{S},4~{R},5~{R},6~{R})-3-oxidanyl-5-[[(3~{R})-3-oxidanyltetradecanoyl]amino]-4-[(3~{R})-3-oxidanyltetradecanoyl]oxy-6-phosphonooxy-oxan-2-yl]methoxy]-3-phosphonooxy-4-[(3~{R})-3-tetradecanoyloxytetradecanoyl]oxy-oxan-2-yl]methoxy]oxan-4-yl]oxy-4,5-bis(oxidanyl)oxane-2-carboxylic acid, Lipopolysaccharide export system ATP-binding protein LptB, Lipopolysaccharide export system permease protein LptF, ... | | 著者 | Orlando, B.J, Li, Y, Liao, M. | | 登録日 | 2018-09-18 | | 公開日 | 2019-04-03 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Structural basis of lipopolysaccharide extraction by the LptB2FGC complex.
Nature, 567, 2019
|
|
6MI8
 | | Cryo-EM Structure of vanadate-trapped E.coli LptB2FGC | | 分子名称: | ADP ORTHOVANADATE, Lipopolysaccharide export system ATP-binding protein LptB, Lipopolysaccharide export system permease protein LptF, ... | | 著者 | Orlando, B.J, Li, Y, Liao, M. | | 登録日 | 2018-09-19 | | 公開日 | 2019-04-03 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | | 主引用文献 | Structural basis of lipopolysaccharide extraction by the LptB2FGC complex.
Nature, 567, 2019
|
|
6MHZ
 | | Vanadate trapped Cryo-EM Structure of E.coli LptB2FG Transporter | | 分子名称: | ADP ORTHOVANADATE, Lipopolysaccharide export system ATP-binding protein LptB, Lipopolysaccharide export system permease protein LptF, ... | | 著者 | Orlando, B.J, Li, Y, Liao, M. | | 登録日 | 2018-09-18 | | 公開日 | 2019-04-03 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | Structural basis of lipopolysaccharide extraction by the LptB2FGC complex.
Nature, 567, 2019
|
|
6MI7
 | | Nucleotide-free Cryo-EM Structure of E.coli LptB2FGC | | 分子名称: | (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, Lipopolysaccharide export system ATP-binding protein LptB, Lipopolysaccharide export system permease protein LptF, ... | | 著者 | Orlando, B.J, Li, Y, Liao, M. | | 登録日 | 2018-09-19 | | 公開日 | 2019-04-03 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Structural basis of lipopolysaccharide extraction by the LptB2FGC complex.
Nature, 567, 2019
|
|
6OIH
 | |
6JB1
 | | Structure of pancreatic ATP-sensitive potassium channel bound with repaglinide and ATPgammaS at 3.3A resolution | | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, ATP-binding cassette sub-family C member 8 isoform X2, ATP-sensitive inward rectifier potassium channel 11, ... | | 著者 | Chen, L, Ding, D, Wang, M, Wu, J.-X, Kang, Y. | | 登録日 | 2019-01-25 | | 公開日 | 2019-05-22 | | 最終更新日 | 2021-09-29 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | The Structural Basis for the Binding of Repaglinide to the Pancreatic KATPChannel.
Cell Rep, 27, 2019
|
|
6JB3
 | | Structure of SUR1 subunit bound with repaglinide | | 分子名称: | ATP-binding cassette sub-family C member 8 isoform X2, Digitonin, Repaglinide | | 著者 | Chen, L, Ding, D, Wang, M, Wu, J.-X, Kang, Y. | | 登録日 | 2019-01-25 | | 公開日 | 2019-05-22 | | 最終更新日 | 2021-09-29 | | 実験手法 | ELECTRON MICROSCOPY (3.001 Å) | | 主引用文献 | The Structural Basis for the Binding of Repaglinide to the Pancreatic KATPChannel.
Cell Rep, 27, 2019
|
|
6QV1
 | | Structure of ATPgS-bound outward-facing TM287/288 in complex with nanobody Nb_TM1 | | 分子名称: | ABC transporter, ATP-binding protein, MAGNESIUM ION, ... | | 著者 | Hutter, C.A.J, Huerlimann, L.M, Zimmermann, I, Egloff, P, Seeger, M.A. | | 登録日 | 2019-03-01 | | 公開日 | 2019-05-29 | | 最終更新日 | 2019-06-05 | | 実験手法 | X-RAY DIFFRACTION (3.48 Å) | | 主引用文献 | The extracellular gate shapes the energy profile of an ABC exporter.
Nat Commun, 10, 2019
|
|
