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6MI7
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BU of 6mi7 by Molmil
Nucleotide-free Cryo-EM Structure of E.coli LptB2FGC
Descriptor: (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, Lipopolysaccharide export system ATP-binding protein LptB, Lipopolysaccharide export system permease protein LptF, ...
Authors:Orlando, B.J, Li, Y, Liao, M.
Deposit date:2018-09-19
Release date:2019-04-03
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Structural basis of lipopolysaccharide extraction by the LptB2FGC complex.
Nature, 567, 2019
6MIT
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BU of 6mit by Molmil
LptBFGC from Enterobacter cloacae
Descriptor: CHLORIDE ION, LPS export ABC transporter permease LptF, Lipopolysaccharide export system ATP-binding protein, ...
Authors:Owens, T.W, Kahne, D, Kruse, A.C.
Deposit date:2018-09-20
Release date:2019-03-27
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural basis of unidirectional export of lipopolysaccharide to the cell surface.
Nature, 567, 2019
6XJI
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BU of 6xji by Molmil
PmtCD ABC exporter at C1 symmetry
Descriptor: ABC transporter ATP-binding protein, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ...
Authors:Zeytuni, N, Strynadka, N.J.C, Hu, J, Worrall, L.J, Chou, H, Yu, Z.
Deposit date:2020-06-23
Release date:2020-10-14
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structural insight into the Staphylococcus aureus ATP-driven exporter of virulent peptide toxins
Sci Adv, 6, 2020
6YIR
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BU of 6yir by Molmil
Crystal structure of Bacillus subtilis MsmX ATPase
Descriptor: Oligosaccharides import ATP-binding protein MsmX, SULFATE ION, TRIETHYLENE GLYCOL
Authors:Leisico, F, Santos-Silva, T, Romao, M.J.
Deposit date:2020-04-01
Release date:2020-11-18
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Multitask ATPases (NBDs) of bacterial ABC importers type I and their interspecies exchangeability.
Sci Rep, 10, 2020
6YAL
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BU of 6yal by Molmil
Mammalian 48S late-stage initiation complex with beta-globin mRNA
Descriptor: 18S ribosomal RNA, 40S Ribosomal protein uS3, 40S Ribosomal protein uS7, ...
Authors:Bochler, A, Simonetti, A, Guca, E, Hashem, Y.
Deposit date:2020-03-12
Release date:2020-04-08
Last modified:2020-04-22
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural Insights into the Mammalian Late-Stage Initiation Complexes.
Cell Rep, 31, 2020
5UAK
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BU of 5uak by Molmil
Dephosphorylated, ATP-free human cystic fibrosis transmembrane conductance regulator (CFTR)
Descriptor: Cystic fibrosis transmembrane conductance regulator
Authors:Liu, F, Zhang, Z, Chen, J.
Deposit date:2016-12-19
Release date:2017-01-18
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.87 Å)
Cite:Molecular Structure of the Human CFTR Ion Channel.
Cell, 169, 2017
5TTP
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BU of 5ttp by Molmil
Cryo-EM structure of MsbA-nanodisc with ADP-vanadate
Descriptor: Lipid A export ATP-binding/permease protein MsbA
Authors:Mi, W, Walz, T, Liao, M.
Deposit date:2016-11-04
Release date:2017-09-20
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:Structural basis of MsbA-mediated lipopolysaccharide transport.
Nature, 549, 2017
5TV4
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BU of 5tv4 by Molmil
3D cryo-EM reconstruction of nucleotide-free MsbA in lipid nanodisc
Descriptor: 3-HYDROXY-TETRADECANOIC ACID, L-glycero-alpha-D-manno-heptopyranose-(1-7)-L-glycero-alpha-D-manno-heptopyranose-(1-3)-L-glycero-alpha-D-manno-heptopyranose-(1-5)-[3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(2-4)]3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(2-6)-2-amino-2-deoxy-alpha-D-glucopyranose-(1-6)-2-amino-2-deoxy-alpha-D-glucopyranose, LAURIC ACID, ...
Authors:Mi, W, Walz, T, Liao, M.
Deposit date:2016-11-08
Release date:2017-09-20
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Structural basis of MsbA-mediated lipopolysaccharide transport.
Nature, 549, 2017
5U1D
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BU of 5u1d by Molmil
Cryo-EM structure of the human TAP ATP-Binding Cassette Transporter
Descriptor: Antigen peptide transporter 1, Antigen peptide transporter 2, TAP transporter inhibitor ICP47
Authors:Oldham, M.L, Chen, J, Grigorieff, N.
Deposit date:2016-11-28
Release date:2017-01-11
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.97 Å)
Cite:Structure of the transporter associated with antigen processing trapped by herpes simplex virus.
Elife, 5, 2016
5TWV
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BU of 5twv by Molmil
Cryo-EM structure of the pancreatic ATP-sensitive K+ channel SUR1/Kir6.2 in the presence of ATP and glibenclamide
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ATP-sensitive inward rectifier potassium channel 11
Authors:Martin, G.M, Yoshioka, C, Chen, J.Z, Shyng, S.L.
Deposit date:2016-11-14
Release date:2017-01-25
Last modified:2019-12-25
Method:ELECTRON MICROSCOPY (6.3 Å)
Cite:Cryo-EM structure of the ATP-sensitive potassium channel illuminates mechanisms of assembly and gating.
Elife, 6, 2017
6ZCE
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BU of 6zce by Molmil
Structure of a yeast ABCE1-bound 43S pre-initiation complex
Descriptor: 18S ribosomal RNA (1719-MER), 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ...
Authors:Kratzat, H, Mackens-Kiani, T, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R.
Deposit date:2020-06-10
Release date:2020-10-07
Last modified:2021-01-13
Method:ELECTRON MICROSCOPY (5.3 Å)
Cite:A structural inventory of native ribosomal ABCE1-43S pre-initiation complexes.
Embo J., 40, 2021
5UAR
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BU of 5uar by Molmil
Dephosphorylated, ATP-free cystic fibrosis transmembrane conductance regulator (CFTR) from zebrafish
Descriptor: Cystic fibrosis transmembrane conductance regulator, DECANE
Authors:Zhang, Z, Chen, J.
Deposit date:2016-12-19
Release date:2017-01-18
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.73 Å)
Cite:Atomic Structure of the Cystic Fibrosis Transmembrane Conductance Regulator.
Cell, 167, 2016
6ZG3
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BU of 6zg3 by Molmil
the structure of ECF PanT transporter in a complex with a nanobody
Descriptor: CA14381 nanobody, CITRIC ACID, Conserved hypothetical membrane protein, ...
Authors:Setyawati, I, Guskov, A, Slotboom, D.J.
Deposit date:2020-06-18
Release date:2021-03-03
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:In vitro reconstitution of dynamically interacting integral membrane subunits of energy-coupling factor transporters.
Elife, 9, 2020
6Z5U
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BU of 6z5u by Molmil
Cryo-EM structure of the A. baumannii MlaBDEF complex bound to APPNHP
Descriptor: ABC transporter ATP-binding protein, ABC transporter permease, Anti-sigma factor antagonist, ...
Authors:Mann, D, Bergeron, J.R.C.
Deposit date:2020-05-27
Release date:2021-05-05
Last modified:2021-07-14
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structure and lipid dynamics in the maintenance of lipid asymmetry inner membrane complex of A. baumannii.
Commun Biol, 4, 2021
5UJ9
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BU of 5uj9 by Molmil
Cryo-EM structure of bovine multidrug resistance protein 1 (MRP1)
Descriptor: bovine multidrug resistance protein 1 (MRP1),Multidrug resistance-associated protein 1
Authors:Johnson, Z.L, Chen, J.
Deposit date:2017-01-17
Release date:2017-02-22
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.49 Å)
Cite:Structural Basis of Substrate Recognition by the Multidrug Resistance Protein MRP1.
Cell, 168, 2017
6ZU9
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BU of 6zu9 by Molmil
Structure of a yeast ABCE1-bound 48S initiation complex
Descriptor: 18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ...
Authors:Kratzat, H, Mackens-Kiani, T, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R.
Deposit date:2020-07-22
Release date:2020-10-28
Last modified:2021-01-13
Method:ELECTRON MICROSCOPY (6.2 Å)
Cite:A structural inventory of native ribosomal ABCE1-43S pre-initiation complexes.
Embo J., 40, 2021
6ZY3
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BU of 6zy3 by Molmil
Cryo-EM structure of MlaFEDB in complex with phospholipid
Descriptor: 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine, ABC transporter maintaining OM lipid asymmetry, cytoplasmic STAS component, ...
Authors:Dong, C.J, Dong, H.H.
Deposit date:2020-07-30
Release date:2020-11-25
Last modified:2021-01-20
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural insights into outer membrane asymmetry maintenance in Gram-negative bacteria by MlaFEDB.
Nat.Struct.Mol.Biol., 28, 2021
6ZME
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BU of 6zme by Molmil
SARS-CoV-2 Nsp1 bound to the human CCDC124-80S-eERF1 ribosome complex
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
Authors:Thoms, M, Buschauer, R, Ameismeier, M, Denk, T, Kratzat, H, Mackens-Kiani, T, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R.
Deposit date:2020-07-02
Release date:2020-08-12
Last modified:2020-09-16
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2.
Science, 369, 2020
6ZVJ
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BU of 6zvj by Molmil
Structure of a human ABCE1-bound 43S pre-initiation complex - State II
Descriptor: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ...
Authors:Kratzat, H, Mackens-Kiani, T, Ameismeier, A, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R.
Deposit date:2020-07-24
Release date:2020-10-07
Last modified:2021-01-13
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:A structural inventory of native ribosomal ABCE1-43S pre-initiation complexes.
Embo J., 40, 2021
6ZY2
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BU of 6zy2 by Molmil
Cryo-EM structure of apo MlaFEDB
Descriptor: ABC transporter maintaining OM lipid asymmetry, cytoplasmic STAS component, Toluene tolerance protein Ttg2A, ...
Authors:Dong, C.J, Dong, H.H.
Deposit date:2020-07-30
Release date:2020-11-25
Last modified:2021-01-20
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structural insights into outer membrane asymmetry maintenance in Gram-negative bacteria by MlaFEDB.
Nat.Struct.Mol.Biol., 28, 2021
7A65
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BU of 7a65 by Molmil
Nanodisc reconstituted, drug-free human ABCB1 in complex with MRK16 Fab
Descriptor: CHOLESTEROL, MRK16 Fab-fragment heavy chain, MRK16 Fab-fragment light chain, ...
Authors:Nosol, K, Locher, K.P.
Deposit date:2020-08-25
Release date:2020-10-14
Last modified:2020-10-28
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Cryo-EM structures reveal distinct mechanisms of inhibition of the human multidrug transporter ABCB1.
Proc.Natl.Acad.Sci.USA, 117, 2020
7A6E
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BU of 7a6e by Molmil
Nanodisc reconstituted human ABCB1 in complex with MRK16 Fab and tariquidar
Descriptor: CHOLESTEROL, MRK16 Fab-fragment heavy chain, MRK16 Fab-fragment light chain, ...
Authors:Nosol, K, Locher, K.P.
Deposit date:2020-08-25
Release date:2020-10-14
Last modified:2020-10-28
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Cryo-EM structures reveal distinct mechanisms of inhibition of the human multidrug transporter ABCB1.
Proc.Natl.Acad.Sci.USA, 117, 2020
7A6C
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BU of 7a6c by Molmil
Nanodisc reconstituted human ABCB1 in complex with MRK16 Fab and elacridar
Descriptor: CHOLESTEROL, If kappa light chain, MRK16 Fab-fragment heavy chain, ...
Authors:Nosol, K, Locher, K.P.
Deposit date:2020-08-25
Release date:2020-10-14
Last modified:2020-10-28
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Cryo-EM structures reveal distinct mechanisms of inhibition of the human multidrug transporter ABCB1.
Proc.Natl.Acad.Sci.USA, 117, 2020
7A69
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BU of 7a69 by Molmil
Nanodisc reconstituted human ABCB1 in complex with MRK16 Fab and vincristine
Descriptor: CHOLESTEROL, MRK16 Fab-fragment heavy chain, MRK16 Fab-fragment light chain, ...
Authors:Nosol, K, Locher, K.P.
Deposit date:2020-08-25
Release date:2020-10-21
Last modified:2020-10-28
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Cryo-EM structures reveal distinct mechanisms of inhibition of the human multidrug transporter ABCB1.
Proc.Natl.Acad.Sci.USA, 117, 2020
7A6F
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BU of 7a6f by Molmil
Nanodisc reconstituted human ABCB1 in complex with MRK16 Fab and zosuquidar
Descriptor: CHOLESTEROL, MRK16 Fab-fragment heavy chain, MRK16 Fab-fragment light chain, ...
Authors:Nosol, K, Locher, K.P.
Deposit date:2020-08-25
Release date:2020-10-14
Last modified:2020-10-28
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Cryo-EM structures reveal distinct mechanisms of inhibition of the human multidrug transporter ABCB1.
Proc.Natl.Acad.Sci.USA, 117, 2020

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