7LMZ
| Cryo-EM structure of human p97 in complex with Npl4/Ufd1 and Ub6 (Class 1) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Hexa-ubiquitin, ... | 著者 | Pan, M, Yu, Y, Liu, L, Zhao, M. | 登録日 | 2021-02-06 | 公開日 | 2021-09-15 | 実験手法 | ELECTRON MICROSCOPY (3.06 Å) | 主引用文献 | Mechanistic insight into substrate processing and allosteric inhibition of human p97. Nat.Struct.Mol.Biol., 28, 2021
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7LN0
| Cryo-EM structure of human p97 in complex with Npl4/Ufd1 and Ub6 (Class 2) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Hexa-ubiquitin, ... | 著者 | Pan, M, Yu, Y, Liu, L, Zhao, M. | 登録日 | 2021-02-06 | 公開日 | 2021-09-15 | 実験手法 | ELECTRON MICROSCOPY (2.98 Å) | 主引用文献 | Mechanistic insight into substrate processing and allosteric inhibition of human p97. Nat.Struct.Mol.Biol., 28, 2021
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7LN1
| Cryo-EM structure of human p97 in complex with Npl4/Ufd1 and Ub6 (Class 3) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Hexa-ubiquitin, ... | 著者 | Pan, M, Yu, Y, Liu, L, Zhao, M. | 登録日 | 2021-02-06 | 公開日 | 2021-09-15 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Mechanistic insight into substrate processing and allosteric inhibition of human p97. Nat.Struct.Mol.Biol., 28, 2021
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7LN2
| Cryo-EM structure of human p97 in complex with Npl4/Ufd1 and polyubiquitinated Ub-Eos (FOM, Class 1) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Pan, M, Yu, Y, Liu, L, Zhao, M. | 登録日 | 2021-02-06 | 公開日 | 2021-09-15 | 実験手法 | ELECTRON MICROSCOPY (3.63 Å) | 主引用文献 | Mechanistic insight into substrate processing and allosteric inhibition of human p97. Nat.Struct.Mol.Biol., 28, 2021
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7LN3
| Cryo-EM structure of human p97 in complex with Npl4/Ufd1 and polyubiquitinated Ub-Eos (FOM, Class 2) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Pan, M, Yu, Y, Liu, L, Zhao, M. | 登録日 | 2021-02-06 | 公開日 | 2021-09-15 | 実験手法 | ELECTRON MICROSCOPY (3.45 Å) | 主引用文献 | Mechanistic insight into substrate processing and allosteric inhibition of human p97. Nat.Struct.Mol.Biol., 28, 2021
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7LN4
| Cryo-EM structure of human p97 in complex with Npl4/Ufd1 and polyubiquitinated Ub-Eos (FOM, Class 3) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Pan, M, Yu, Y, Liu, L, Zhao, M. | 登録日 | 2021-02-06 | 公開日 | 2021-09-15 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Mechanistic insight into substrate processing and allosteric inhibition of human p97. Nat.Struct.Mol.Biol., 28, 2021
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7LN5
| Cryo-EM structure of human p97 in complex with Npl4/Ufd1 and polyubiquitinated Ub-Eos (CHAPSO, Class 1, Close State) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Pan, M, Yu, Y, Liu, L, Zhao, M. | 登録日 | 2021-02-06 | 公開日 | 2021-09-15 | 実験手法 | ELECTRON MICROSCOPY (3.09 Å) | 主引用文献 | Mechanistic insight into substrate processing and allosteric inhibition of human p97. Nat.Struct.Mol.Biol., 28, 2021
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7LN6
| Cryo-EM structure of human p97 in complex with Npl4/Ufd1 and polyubiquitinated Ub-Eos (CHAPSO, Class 2, Open State) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Pan, M, Yu, Y, Liu, L, Zhao, M. | 登録日 | 2021-02-06 | 公開日 | 2021-09-15 | 実験手法 | ELECTRON MICROSCOPY (3.58 Å) | 主引用文献 | Mechanistic insight into substrate processing and allosteric inhibition of human p97. Nat.Struct.Mol.Biol., 28, 2021
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7MCA
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7MDM
| Structure of human p97 ATPase L464P mutant | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase | 著者 | Zhang, X, Gui, L, Li, S, Nandi, P, Columbres, R.C, Wong, D.E, Moen, D.R, Lin, H.J, Chiu, P.-L, Chou, T.-F. | 登録日 | 2021-04-05 | 公開日 | 2021-08-25 | 最終更新日 | 2021-09-22 | 実験手法 | ELECTRON MICROSCOPY (4.86 Å) | 主引用文献 | Conserved L464 in p97 D1-D2 linker is critical for p97 cofactor regulated ATPase activity. Biochem.J., 478, 2021
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7MDO
| Structure of human p97 ATPase L464P mutant | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase | 著者 | Zhang, X, Gui, L, Li, S, Nandi, P, Columbres, R.C, Wong, D.E, Moen, D.R, Lin, H.J, Chiu, P.-L, Chou, T.-F. | 登録日 | 2021-04-05 | 公開日 | 2021-08-25 | 最終更新日 | 2021-09-22 | 実験手法 | ELECTRON MICROSCOPY (4.12 Å) | 主引用文献 | Conserved L464 in p97 D1-D2 linker is critical for p97 cofactor regulated ATPase activity. Biochem.J., 478, 2021
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7MHB
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7MHS
| Structure of p97 (subunits A to E) with substrate engaged | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, ... | 著者 | Xu, Y, Han, H, Cooney, I, Hill, C.P, Shen, P.S. | 登録日 | 2021-04-15 | 公開日 | 2022-05-11 | 最終更新日 | 2022-11-23 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Active conformation of the p97-p47 unfoldase complex. Nat Commun, 13, 2022
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7NFY
| P1a-state of wild type human mitochondrial LONP1 protease with bound substrate protein and ATPgS | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Lon protease homolog, mitochondrial, ... | 著者 | Mohammed, I, Schmitz, K.A, Schenck, N, Maier, T, Abrahams, J.P. | 登録日 | 2021-02-08 | 公開日 | 2021-02-24 | 最終更新日 | 2022-11-09 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Catalytic cycling of human mitochondrial Lon protease. Structure, 30, 2022
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7NG4
| P1b-state of wild type human mitochondrial LONP1 protease with bound endogenous substrate protein and in presence of ATP/ADP mix | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Lon protease homolog, ... | 著者 | Mohammed, I, Schmitz, K.A, Schenck, N, Maier, T, Abrahams, J.P. | 登録日 | 2021-02-08 | 公開日 | 2021-02-24 | 最終更新日 | 2022-11-09 | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | 主引用文献 | Catalytic cycling of human mitochondrial Lon protease. Structure, 30, 2022
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7NG5
| P1c-state of wild type human mitochondrial LONP1 protease with bound substrate protein in presence of ATP/ADP mix | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Lon protease homolog, ... | 著者 | Mohammed, I, Schmitz, K.A, Schenck, N, Maier, T, Abrahams, J.P. | 登録日 | 2021-02-08 | 公開日 | 2021-02-24 | 最終更新日 | 2022-11-09 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Catalytic cycling of human mitochondrial Lon protease. Structure, 30, 2022
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7NGC
| P2a-state of wild type human mitochondrial LONP1 protease with bound substrate protein and in presence of ATPgS | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Lon protease homolog, mitochondrial, ... | 著者 | Mohammed, I, Schmitz, K.A, Schenck, N, Maier, T, Abrahams, J.P. | 登録日 | 2021-02-09 | 公開日 | 2021-04-07 | 最終更新日 | 2022-11-09 | 実験手法 | ELECTRON MICROSCOPY (7.5 Å) | 主引用文献 | Catalytic cycling of human mitochondrial Lon protease. Structure, 30, 2022
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7NGF
| P2c-state of wild type human mitochondrial LONP1 protease with bound endogenous substrate protein and in presence of ATP/ADP mix | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Lon protease homolog, ... | 著者 | Mohammed, I, Schmitz, K.A, Schenck, N, Maier, T, Abrahams, J.P. | 登録日 | 2021-02-09 | 公開日 | 2021-04-28 | 最終更新日 | 2022-11-09 | 実験手法 | ELECTRON MICROSCOPY (5.6 Å) | 主引用文献 | Catalytic cycling of human mitochondrial Lon protease. Structure, 30, 2022
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7NGL
| R-state of wild type human mitochondrial LONP1 protease bound to endogenous ADP | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Lon protease homolog, mitochondrial | 著者 | Mohammed, I, Schmitz, K.A, Schenck, N, Maier, T, Abrahams, J.P. | 登録日 | 2021-02-09 | 公開日 | 2021-04-28 | 最終更新日 | 2022-11-09 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Catalytic cycling of human mitochondrial Lon protease. Structure, 30, 2022
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7NGP
| D1-state of wild type human mitochondrial LONP1 protease | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Lon protease homolog, mitochondrial | 著者 | Mohammed, I, Schmitz, K.A, Schenck, N, Maier, T, Abrahams, J.P. | 登録日 | 2021-02-09 | 公開日 | 2021-04-28 | 最終更新日 | 2022-11-09 | 実験手法 | ELECTRON MICROSCOPY (15 Å) | 主引用文献 | Catalytic cycling of human mitochondrial Lon protease. Structure, 30, 2022
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7NGQ
| Human mitochondrial Lon protease homolog, D2-state | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Lon protease homolog, mitochondrial | 著者 | Mohammed, I, Abrahams, J.P, Schmitz, K.A, Maier, T, Schenck, N. | 登録日 | 2021-02-09 | 公開日 | 2021-04-28 | 最終更新日 | 2022-11-09 | 実験手法 | ELECTRON MICROSCOPY (12 Å) | 主引用文献 | Catalytic cycling of human mitochondrial Lon protease. Structure, 30, 2022
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7NKU
| diazaborine bound Drg1(AFG2) | 分子名称: | 6-METHYL-2(PROPANE-1-SULFONYL)-2H-THIENO[3,2-D][1,2,3]DIAZABORININ-1-OL, ATPase family gene 2 protein, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER | 著者 | Prattes, M, Bergler, H, Haselbach, D. | 登録日 | 2021-02-19 | 公開日 | 2021-06-23 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structural basis for inhibition of the AAA-ATPase Drg1 by diazaborine. Nat Commun, 12, 2021
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7OAT
| Structural basis for targeted p97 remodelling by ASPL as prerequisite for p97 trimethylation by METTL21D | 分子名称: | 1,2-ETHANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Petrovic, S, Heinemann, U, Roske, Y. | 登録日 | 2021-04-20 | 公開日 | 2022-08-03 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.995 Å) | 主引用文献 | Structural remodeling of AAA+ ATPase p97 by adaptor protein ASPL facilitates posttranslational methylation by METTL21D. Proc.Natl.Acad.Sci.USA, 120, 2023
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7OXO
| human LonP1, R-state, incubated in AMPPCP | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Lon protease homolog, mitochondrial | 著者 | Abrahams, J.P, Mohammed, I, Schmitz, K.A, Schenck, N, Maier, T. | 登録日 | 2021-06-22 | 公開日 | 2021-12-22 | 最終更新日 | 2022-11-09 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Catalytic cycling of human mitochondrial Lon protease. Structure, 30, 2022
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7P09
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