7NKU
diazaborine bound Drg1(AFG2)
Summary for 7NKU
Entry DOI | 10.2210/pdb7nku/pdb |
EMDB information | 12448 |
Descriptor | ATPase family gene 2 protein, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, 6-METHYL-2(PROPANE-1-SULFONYL)-2H-THIENO[3,2-D][1,2,3]DIAZABORININ-1-OL (3 entities in total) |
Functional Keywords | drg1, afg2, ribosome maturation, aaa protein, diazaborine, inhibitor, ribosome |
Biological source | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
Total number of polymer chains | 6 |
Total formula weight | 517016.19 |
Authors | |
Primary citation | Prattes, M.,Grishkovskaya, I.,Hodirnau, V.V.,Rossler, I.,Klein, I.,Hetzmannseder, C.,Zisser, G.,Gruber, C.C.,Gruber, K.,Haselbach, D.,Bergler, H. Structural basis for inhibition of the AAA-ATPase Drg1 by diazaborine. Nat Commun, 12:3483-3483, 2021 Cited by PubMed: 34108481DOI: 10.1038/s41467-021-23854-x PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.4 Å) |
Structure validation
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