PDB: 316 件ウェブページステータス検索Chemie searchBIRD

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3VN9	Rifined Crystal structure of non-phosphorylated MAP2K6 in a putative auto-inhibition state 分子名称: 9-{5-O-[(R)-hydroxy{[(S)-hydroxy(phosphonoamino)phosphoryl]oxy}phosphoryl]-beta-L-ribofuranosyl}-9H-purin-6-amine, Dual specificity mitogen-activated protein kinase kinase 6, MAGNESIUM ION 著者 Kinoshita, T, Matsuzaka, H, Nakai, R, Kirii, Y, Yokota, K, Tada, T, Matsumoto, T. 登録日 2012-01-05 公開日 2012-02-29 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Crystal structure of non-phosphorylated MAP2K6 in a putative auto-inhibition state J.Biochem., 151, 2012
5OY5	Monomeric crystal structure of RpBphP1 photosensory core domain from the bacterium Rhodopseudomonas palustris 分子名称: BILIVERDINE IX ALPHA, BphP1 著者 Papiz, M.Z, Bellini, D. 登録日 2017-09-07 公開日 2019-02-06 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Insights into the light-induced molecular switch of the bacteriophytochrome RpBphP1 probed by SAXS, modelling and UV-Vis optical properties To Be Published
4JCT	ClpP2 from Listeria monocytogenes 分子名称: ATP-dependent Clp protease proteolytic subunit 著者 Zeiler, E, List, A, Alte, F, Gersch, M, Wachtel, R, Groll, M, Sieber, S. 登録日 2013-02-22 公開日 2013-06-12 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural and functional insights into caseinolytic proteases reveal an unprecedented regulation principle of their catalytic triad. Proc.Natl.Acad.Sci.USA, 110, 2013
7X6H	Outer membrane lipoprotein QseG of Escherichia coli O157:H7 分子名称: Quorum-sensing regulator protein G 著者 Matsumoto, K, Fukuda, Y, Inoue, T. 登録日 2022-03-07 公開日 2023-03-15 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Crystal structures of QseE and QseG: elements of a three-component system from Escherichia coli. Acta Crystallogr.,Sect.F, 79, 2023
3NAR	Crystal structure of ZHX1 HD4 (zinc-fingers and homeoboxes protein 1, homeodomain 4) 分子名称: SULFATE ION, Zinc fingers and homeoboxes protein 1 著者 Ren, J, Bird, L.E, Owens, R.J, Stammers, D.K, Oxford Protein Production Facility (OPPF) 登録日 2010-06-02 公開日 2010-07-07 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Novel structural features in two ZHX homeodomains derived from a systematic study of single and multiple domains Bmc Struct.Biol., 10, 2010
3VJI	Human PPAR gamma ligand binding domain in complex with JKPL53 分子名称: (2S)-2-{4-butoxy-3-[({4-[(3S,5S,7S)-tricyclo[3.3.1.1~3,7~]dec-1-yl]benzoyl}amino)methyl]benzyl}butanoic acid, Peroxisome proliferator-activated receptor gamma 著者 Tomioka, D, Kuwabara, N, Hashimoto, H, Sato, M, Shimizu, T. 登録日 2011-10-20 公開日 2012-08-29 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.61 Å) 主引用文献 Peroxisome proliferator-activated receptors (PPARs) have multiple binding points that accommodate ligands in various conformations: phenylpropanoic acid-type PPAR ligands bind to PPAR in different conformations, depending on the subtype. J.Med.Chem., 55, 2012
4N0O	Complex structure of Arterivirus nonstructural protein 10 (helicase) with DNA 分子名称: CALCIUM ION, DNA, Replicase polyprotein 1ab, ... 著者 Deng, Z, Chen, Z. 登録日 2013-10-02 公開日 2014-01-08 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Structural basis for the regulatory function of a complex zinc-binding domain in a replicative arterivirus helicase resembling a nonsense-mediated mRNA decay helicase. Nucleic Acids Res., 42, 2014
6D8Z	Crystal Structure of the C-terminal Guanine Nucleotide Exchange Factor Module of Human Trio 分子名称: Triple functional domain protein 著者 Bandekar, S, Tesmer, J.J. 登録日 2018-04-27 公開日 2019-02-20 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Structure of the C-terminal guanine nucleotide exchange factor module of Trio in an autoinhibited conformation reveals its oncogenic potential. Sci Signal, 12, 2019
6QRJ	Crystal structure of ShkA full-length in complex with AMPPNP 分子名称: Hybrid kinase, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER 著者 Dubey, B.N, Schirmer, T. 登録日 2019-02-19 公開日 2020-01-08 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Hybrid histidine kinase activation by cyclic di-GMP-mediated domain liberation. Proc.Natl.Acad.Sci.USA, 117, 2020
5V7W	Crystal structure of human PARP14 bound to 2-{[(1-methylpiperidin-4-yl)methyl]amino}-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4(3H)-one inhibitor 分子名称: 2-{[(1-methylpiperidin-4-yl)methyl]amino}-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4(3H)-one, Poly [ADP-ribose] polymerase 14 著者 saikatendu, k.s, Hirozane, M. 登録日 2017-03-20 公開日 2017-05-10 最終更新日 2018-11-14 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Identification of PARP14 inhibitors using novel methods for detecting auto-ribosylation. Biochem. Biophys. Res. Commun., 486, 2017
4MDZ	Crystal structure of a HD-GYP domain (a cyclic-di-GMP phosphodiesterase) containing a tri-nuclear metal centre 分子名称: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), FE (III) ION, Metal dependent phosphohydrolase, ... 著者 Bellini, D, Walsh, M.A, Oxford Protein Production Facility (OPPF) 登録日 2013-08-23 公開日 2014-02-19 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.68 Å) 主引用文献 Crystal structure of an HD-GYP domain cyclic-di-GMP phosphodiesterase reveals an enzyme with a novel trinuclear catalytic iron centre. Mol.Microbiol., 91, 2014
8AGU	Yeast RQC complex in state E 分子名称: 25S rRNA, 5.8S rRNA, 5S rRNA, ... 著者 Tesina, P, Buschauer, R, Beckmann, R. 登録日 2022-07-20 公開日 2023-03-08 実験手法 ELECTRON MICROSCOPY (2.7 Å) 主引用文献 Molecular basis of eIF5A-dependent CAT tailing in eukaryotic ribosome-associated quality control. Mol.Cell, 83, 2023
4DSB	Complex Structure of Abscisic Acid Receptor PYL3 with (+)-ABA in Spacegroup of I 212121 at 2.70A 分子名称: (2Z,4E)-5-[(1S)-1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl]-3-methylpenta-2,4-dienoic acid, Abscisic acid receptor PYL3 著者 Zhang, X, Zhang, Q, Chen, Z. 登録日 2012-02-18 公開日 2012-06-06 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Complex Structures of the Abscisic Acid Receptor PYL3/RCAR13 Reveal a Unique Regulatory Mechanism Structure, 20, 2012
5ZVJ	Crystal structure of HtrA1 from Mycobacterium tuberculosis 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Serine protease 著者 Khundrakpam, H.S, Yadav, S, Kumar, D, Biswal, B.K. 登録日 2018-05-10 公開日 2018-09-05 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 The crystal structure of an essential high-temperature requirement protein HtrA1 (Rv1223) from Mycobacterium tuberculosis reveals its unique features. Acta Crystallogr D Struct Biol, 74, 2018
4FWF	Complex structure of LSD2/AOF1/KDM1b with H3K4 mimic 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Histone H3.1, Lysine-specific histone demethylase 1B, ... 著者 Zhang, Q, Chen, Z. 登録日 2012-07-01 公開日 2013-01-16 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structure-function analysis reveals a novel mechanism for regulation of histone demethylase LSD2/AOF1/KDM1b Cell Res., 23, 2013
4AWB	Crystal structure of active legumain in complex with AAN-CMK 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, LEGUMAIN, MERCURY (II) ION, ... 著者 Dall, E, Brandstetter, H. 登録日 2012-06-01 公開日 2013-06-26 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Mechanistic and Structural Studies on Legumain Explain its Zymogenicity, Distinct Activation Pathways, and Regulation Proc.Natl.Acad.Sci.USA, 110, 2013
4GZ9	Mouse Neuropilin-1, extracellular domains 1-4 (a1a2b1b2) 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... 著者 Janssen, B.J.C, Malinauskas, T, Siebold, C, Jones, E.Y. 登録日 2012-09-06 公開日 2012-10-17 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Neuropilins lock secreted semaphorins onto plexins in a ternary signaling complex. Nat.Struct.Mol.Biol., 19, 2012
6PH3	LOV-PAS construct from the LOV-HK sensory protein from Brucella abortus (dark-adapted, construct 15-273) 分子名称: Blue-light-activated histidine kinase, FLAVIN MONONUCLEOTIDE 著者 Rinaldi, J, Otero, L.H, Fernandez, I, Goldbaum, F.A, Shin, H, Yang, X, Klinke, S. 登録日 2019-06-25 公開日 2020-12-30 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.74 Å) 主引用文献 Dimer Asymmetry and Light Activation Mechanism in Brucella Blue-Light Sensor Histidine Kinase. Mbio, 12, 2021
3T9Q	Structure of the Phosphatase Domain of the Cell Fate Determinant SpoIIE from Bacillus subtilis (Mn presoaked) 分子名称: MANGANESE (II) ION, Stage II sporulation protein E, beta-D-gulopyranose 著者 Levdikov, V.M, Blagova, E.V, Wilkinson, A.J. 登録日 2011-08-03 公開日 2011-12-07 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.76 Å) 主引用文献 Structure of the phosphatase domain of the cell fate determinant SpoIIE from Bacillus subtilis. J.Mol.Biol., 415, 2012
4NV5	C50A mutant of Synechococcus VKOR, C2 crystal form (dehydrated) 分子名称: UBIQUINONE-10, VKORC1/thioredoxin domain protein 著者 Liu, S, Cheng, W, Fowle Grider, R, Shen, G, Li, W. 登録日 2013-12-04 公開日 2014-02-12 実験手法 X-RAY DIFFRACTION (2.79 Å) 主引用文献 Structures of an intramembrane vitamin K epoxide reductase homolog reveal control mechanisms for electron transfer. Nat Commun, 5, 2014
6CJ5	Crystal Structure of Mnk2-D228G in Complex With Inhibitor 分子名称: 3-(pyridin-3-yl)imidazo[1,2-a]pyridine-8-carboxamide, MAP kinase-interacting serine/threonine-protein kinase 2, ZINC ION 著者 Han, Q. 登録日 2018-02-26 公開日 2018-05-09 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structure-based Design of Pyridone-Aminal eFT508 Targeting Dysregulated Translation by Selective Mitogen-activated Protein Kinase Interacting Kinases 1 and 2 (MNK1/2) Inhibition. J. Med. Chem., 61, 2018
6ZXC	Diguanylate cyclase DgcR (I-site mutant) in activated state 分子名称: 3'-DEOXY-GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Putative GGDEF/response regulator receiver domain protein 著者 Teixeira, R.D, Schirmer, T. 登録日 2020-07-29 公開日 2021-03-31 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Activation mechanism of a small prototypic Rec-GGDEF diguanylate cyclase. Nat Commun, 12, 2021
6PPS	A blue light illuminated LOV-PAS construct from the LOV-HK sensory protein from Brucella abortus (construct 15-273) 分子名称: Blue-light-activated histidine kinase, FLAVIN MONONUCLEOTIDE 著者 Rinaldi, J, Fernandez, I, Shin, H, Gunawardana, S, Otero, L.H, Cerutti, M.L, Yang, X, Klinke, S, Goldbaum, F.A. 登録日 2019-07-08 公開日 2020-07-15 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Dimer Asymmetry and Light Activation Mechanism in Brucella Blue-Light Sensor Histidine Kinase. Mbio, 12, 2021
3V5I	The crystal structure of the mutant ClpP S98A (Staphylococcus aureus) 分子名称: ATP-dependent Clp protease proteolytic subunit 著者 List, A, Gersch, M, Groll, M, Sieber, S. 登録日 2011-12-16 公開日 2012-02-08 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Insights into structural network responsible for oligomerization and activity of bacterial virulence regulator caseinolytic protease P (ClpP) protein. J.Biol.Chem., 287, 2012
4JJ3	Crystal structure of MamP soaked with iron(II) 分子名称: HEME C, MamP 著者 Siponen, M, Pignol, D, Arnoux, P. 登録日 2013-03-07 公開日 2013-10-09 最終更新日 2018-10-31 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structural insight into magnetochrome-mediated magnetite biomineralization. Nature, 502, 2013

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