PDB: 316 件ウェブページステータス検索Chemie searchBIRD

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4B2M	COMPLEXES OF DODECIN WITH FLAVIN AND FLAVIN-LIKE LIGANDS 分子名称: CHLORIDE ION, DODECIN, MAGNESIUM ION, ... 著者 Staudt, H, Hoesl, M, Dreuw, A, Serdjukow, S, Oesterhelt, D, Budisa, N, Wachtveitl, J, Grininger, M. 登録日 2012-07-16 公開日 2013-05-29 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 The flavoprotein dodecin as a redox probe for electron transfer through DNA. Angew.Chem.Int.Ed.Engl., 52, 2013
4MFQ	The crystal structure of acyltransferase in complex with CoA and 10C-Teicoplanin 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-amino-2-deoxy-beta-D-glucopyranose, COENZYME A, ... 著者 Lyu, S.Y, Liu, Y.C, Chang, C.Y, Huang, C.J, Li, T.L. 登録日 2013-08-28 公開日 2014-09-03 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Multiple complexes of long aliphatic N-acyltransferases lead to synthesis of 2,6-diacylated/2-acyl-substituted glycopeptide antibiotics, effectively killing vancomycin-resistant enterococcus J.Am.Chem.Soc., 136, 2014
4BIX	Crystal structure of CpxAHDC (monoclinic form 1) 分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, SENSOR PROTEIN CPXA, ... 著者 Mechaly, A.E, Sassoon, N, Betton, J.M, Alzari, P.M. 登録日 2013-04-13 公開日 2014-02-12 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Segmental Helical Motions and Dynamical Asymmetry Modulate Histidine Kinase Autophosphorylation. Plos Biol., 12, 2014
6C6H	Structure of glycolipid aGSA[8,P5m] in complex with mouse CD1d 分子名称: (5R,6S,7S)-5,6-dihydroxy-7-(octanoylamino)-N-(3-pentylphenyl)-8-{[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)te trahydro-2H-pyran-2-yl]oxy}octanamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d1, ... 著者 Zajonc, D.M, Wang, J. 登録日 2018-01-18 公開日 2019-01-30 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 A molecular switch in mouse CD1d modulates natural killer T cell activation by alpha-galactosylsphingamides. J.Biol.Chem., 294, 2019
4H5C	Crystal structure of human FPPS in ternary complex with YS0470 and inorganic phosphate 分子名称: Farnesyl pyrophosphate synthase, MAGNESIUM ION, PHOSPHATE ION, ... 著者 Park, J, Lin, Y.-S, Tsantrizos, Y.S, Berghuis, A.M. 登録日 2012-09-18 公開日 2012-12-26 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.02 Å) 主引用文献 Ternary complex structures of human farnesyl pyrophosphate synthase bound with a novel inhibitor and secondary ligands provide insights into the molecular details of the enzyme's active site closure. Bmc Struct.Biol., 12, 2012
4H5D	Crystal structure of human FPPS in ternary complex with YS0470 and inorganic pyrophosphate 分子名称: Farnesyl pyrophosphate synthase, MAGNESIUM ION, PYROPHOSPHATE 2-, ... 著者 Park, J, Lin, Y.-S, Tsantrizos, Y.S, Berghuis, A.M. 登録日 2012-09-18 公開日 2012-12-26 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.02 Å) 主引用文献 Ternary complex structures of human farnesyl pyrophosphate synthase bound with a novel inhibitor and secondary ligands provide insights into the molecular details of the enzyme's active site closure. Bmc Struct.Biol., 12, 2012
8STN	Crystal structure of KRAS-G12D/G75A mutant, GDP-bound 分子名称: CHLORIDE ION, GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, ... 著者 Tran, T.H, Dharmaiah, S, Simanshu, D.K. 登録日 2023-05-10 公開日 2023-08-23 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 Allosteric Regulation of Switch-II Domain Controls KRAS Oncogenicity. Cancer Res., 83, 2023
4MCW	Crystal structure of a HD-GYP domain (a cyclic-di-GMP phosphodiesterase) containing a tri-nuclear metal centre 分子名称: 1,2-ETHANEDIOL, FE (III) ION, IMIDAZOLE, ... 著者 Bellini, D, Walsh, M.A, Oxford Protein Production Facility (OPPF) 登録日 2013-08-21 公開日 2014-02-19 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 Crystal structure of an HD-GYP domain cyclic-di-GMP phosphodiesterase reveals an enzyme with a novel trinuclear catalytic iron centre. Mol.Microbiol., 91, 2014
4H5E	Crystal structure of human FPPS in ternary complex with YS0470 and isopentenyl pyrophosphate 分子名称: Farnesyl pyrophosphate synthase, ISOPENTYL PYROPHOSPHATE, MAGNESIUM ION, ... 著者 Park, J, Lin, Y.-S, Tsantrizos, Y.S, Berghuis, A.M. 登録日 2012-09-18 公開日 2012-12-26 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.04 Å) 主引用文献 Ternary complex structures of human farnesyl pyrophosphate synthase bound with a novel inhibitor and secondary ligands provide insights into the molecular details of the enzyme's active site closure. Bmc Struct.Biol., 12, 2012
6CXE	Structure of alpha-GSA[26,6P] bound by CD1d and in complex with the Va14Vb8.2 TCR 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d1, ... 著者 Wang, J, Zajonc, D. 登録日 2018-04-02 公開日 2019-04-10 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 A molecular switch in mouse CD1d modulates natural killer T cell activation by alpha-galactosylsphingamides. J.Biol.Chem., 294, 2019
4I09	structure of the mutant Catabolite gene activator protein V132L 分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Catabolite gene activator 著者 Pohl, E, Townsend, P.D, Rodgers, T, Burnell, D, McLeish, T.C.B, Wilson, M.R, Cann, M.J. 登録日 2012-11-16 公開日 2013-10-30 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Modulation of global low-frequency motions underlies allosteric regulation: demonstration in CRP/FNR family transcription factors. Plos Biol., 11, 2013
7VW9	Helicoverpa armigera pheromone-binding protein PBP1 at pH 5.5 分子名称: PBP1 著者 Zheng, J, Chen, Z. 登録日 2021-11-10 公開日 2022-02-02 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Structural Insights into the Ligand-Binding and -Releasing Mechanism of Helicoverpa armigera Pheromone-Binding Protein PBP1. Int J Mol Sci, 23, 2022
4JC3	14-3-3 protein interaction with Estrogen Receptor Alpha provides a novel drug target interface 分子名称: 14-3-3 protein sigma, Estrogen receptor Peptide, MAGNESIUM ION 著者 Bier, D, Ottmann, C. 登録日 2013-02-21 公開日 2013-05-15 最終更新日 2017-06-07 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Interaction of 14-3-3 proteins with the estrogen receptor alpha F domain provides a drug target interface. Proc. Natl. Acad. Sci. U.S.A., 110, 2013
4HEH	Crystal structure of AppA SCHIC domain from Rb. sphaeroides 分子名称: AppA protein 著者 Dragnea, V, Yin, L, Dann III, C.E, Bauer, C.E. 登録日 2012-10-03 公開日 2013-09-18 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Redox and light control the heme-sensing activity of AppA. MBio, 4, 2013
4F9C	Human CDC7 kinase in complex with DBF4 and XL413 分子名称: 8-chloro-2-[(2S)-pyrrolidin-2-yl][1]benzofuro[3,2-d]pyrimidin-4(3H)-one, Cell division cycle 7-related protein kinase, Protein DBF4 homolog A, ... 著者 Hughes, S, Cherepanov, P. 登録日 2012-05-18 公開日 2012-10-31 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.08 Å) 主引用文献 Crystal structure of human CDC7 kinase in complex with its activator DBF4. Nat.Struct.Mol.Biol., 19, 2012
4HI3	Crystal structure of dimeric R298A mutant of SARS coronavirus main protease 分子名称: 3C-like proteinase 著者 Wu, C.-G, Chou, C.-Y. 登録日 2012-10-11 公開日 2013-05-01 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.09 Å) 主引用文献 Mechanism for controlling the monomer-dimer conversion of SARS coronavirus main protease. Acta Crystallogr.,Sect.D, 69, 2013
3TPO	Crystal structure of D192A/E396A mutant of mouse importin alpha2 分子名称: Importin subunit alpha-2 著者 Hirano, H, Matsuura, Y. 登録日 2011-09-08 公開日 2011-10-12 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Sensing actin dynamics: structural basis for G-actin-sensitive nuclear import of MAL Biochem.Biophys.Res.Commun., 414, 2011
3UET	Crystal structure of alpha-1,3/4-fucosidase from Bifidobacterium longum subsp. infantis D172A/E217A mutant complexed with lacto-N-fucopentaose II 分子名称: 1,2-ETHANEDIOL, Alpha-1,3/4-fucosidase, SODIUM ION, ... 著者 Sakurama, H, Fushinobu, S, Yoshida, E, Honda, Y, Hidaka, M, Ashida, H, Kitaoka, M, Katayama, T, Yamamoto, K, Kumagai, H. 登録日 2011-10-31 公開日 2012-04-04 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 1,3-1,4-alpha-L-fucosynthase that specifically introduces Lewis a/x antigens into type-1/2 chains J.Biol.Chem., 287, 2012
4JCR	ClpP1 N165D mutant from Listeria monocytogenes 分子名称: ATP-dependent Clp protease proteolytic subunit 著者 Zeiler, E, List, A, Alte, F, Gersch, M, Wachtel, R, Groll, M, Sieber, S. 登録日 2013-02-22 公開日 2013-06-12 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural and functional insights into caseinolytic proteases reveal an unprecedented regulation principle of their catalytic triad. Proc.Natl.Acad.Sci.USA, 110, 2013
4JDD	14-3-3 protein interaction with Estrogen Receptor Alpha provides a novel drug target interface 分子名称: 14-3-3 protein sigma, Estrogen receptor Peptide, FUSICOCCIN 著者 Bier, D, Ottmann, C. 登録日 2013-02-25 公開日 2013-05-15 最終更新日 2017-06-07 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Interaction of 14-3-3 proteins with the estrogen receptor alpha F domain provides a drug target interface. Proc. Natl. Acad. Sci. U.S.A., 110, 2013
4MFZ	The crystal structure of acyltransferase in complex with decanoyl-CoA 分子名称: Dbv8 protein, SODIUM ION, SULFATE ION, ... 著者 Lyu, S.Y, Liu, Y.C, Chang, C.Y, Huang, C.J, Li, T.L. 登録日 2013-08-28 公開日 2014-09-03 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Multiple complexes of long aliphatic N-acyltransferases lead to synthesis of 2,6-diacylated/2-acyl-substituted glycopeptide antibiotics, effectively killing vancomycin-resistant enterococcus J.Am.Chem.Soc., 136, 2014
3TPM	Crystal structure of MAL RPEL domain in complex with importin-alpha 分子名称: Importin subunit alpha-2, MAL 著者 Hirano, H, Matsuura, Y. 登録日 2011-09-08 公開日 2011-10-12 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Sensing actin dynamics: structural basis for G-actin-sensitive nuclear import of MAL Biochem.Biophys.Res.Commun., 414, 2011
4JPY	Iron and phenylalanine bound crystal structure of phenylalanine hydroxylase from Chromobacterium violaceum 分子名称: FE (III) ION, PHENYLALANINE, Phenylalanine-4-hydroxylase 著者 Ronau, J.A, Abu-Omar, M.M, Das, C. 登録日 2013-03-19 公開日 2013-08-07 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.13 Å) 主引用文献 An additional substrate binding site in a bacterial phenylalanine hydroxylase. Eur.Biophys.J., 42, 2013
4FWE	Native structure of LSD2 /AOF1/KDM1b in spacegroup of C2221 at 2.13A 分子名称: CITRATE ANION, FLAVIN-ADENINE DINUCLEOTIDE, Lysine-specific histone demethylase 1B, ... 著者 Zhang, Q, Chen, Z. 登録日 2012-07-01 公開日 2013-01-16 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.13 Å) 主引用文献 Structure-function analysis reveals a novel mechanism for regulation of histone demethylase LSD2/AOF1/KDM1b Cell Res., 23, 2013
4EUX	Structure of neuronal nitric oxide synthase heme domain in complex with 6-(5-(((3R,4R)-4-((6-amino-4-methylpyridin-2-yl)methyl)pyrrolidin-3-yl)oxy)pentyl)-4-methylpyridin-2-amine 分子名称: 5,6,7,8-TETRAHYDROBIOPTERIN, 6-[5-({(3R,4R)-4-[(6-amino-4-methylpyridin-2-yl)methyl]pyrrolidin-3-yl}oxy)pentyl]-4-methylpyridin-2-amine, ACETATE ION, ... 著者 Li, H, Poulos, T.L. 登録日 2012-04-25 公開日 2012-07-11 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.14 Å) 主引用文献 Selective monocationic inhibitors of neuronal nitric oxide synthase. Binding mode insights from molecular dynamics simulations. J.Am.Chem.Soc., 134, 2012

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