PDB: 316 resultsInfo pagesStatus searchChemie searchBIRD

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3WJG	Crystal structure of mutant nitrobindin M75L/H76L/Q96C/M148W/H158L (NB10) from Arabidopsis thaliana Descriptor: GLYCEROL, UPF0678 fatty acid-binding protein-like protein At1g79260 Authors: Mizohata, E, Fukumoto, K, Onoda, A, Bocola, M, Arlt, M, Inoue, T, Schwaneberg, U, Hayashi, T. Deposit date: 2013-10-08 Release date: 2014-04-02 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (1.1 Å) Cite: A Rhodium Complex-linked Hybrid Biocatalyst: Stereo-controlled Phenylacetylene Polymerization within an Engineered Protein Cavity CHEMCATCHEM, 2014
3WD0	Serratia marcescens Chitinase B, tetragonal form Descriptor: Chitinase B, DITHIANE DIOL, GLYCEROL, ... Authors: Hirose, T, Maita, N, Gouda, H, Koseki, J, Yamamoto, T, Sugawara, A, Nakano, H, Hirono, S, Shiomi, K, Watanabe, T, Taniguchi, H, Sharpless, K.B, Omura, S, Sunazuka, T. Deposit date: 2013-06-06 Release date: 2013-09-18 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Observation of the controlled assembly of preclick components in the in situ click chemistry generation of a chitinase inhibitor Proc.Natl.Acad.Sci.USA, 110, 2013
4L01	Crystal structure of the V658F apo Jak1 pseudokinase domain Descriptor: Tyrosine-protein kinase JAK1 Authors: Toms, A.V, Rogers, J.M, Eck, M.J. Deposit date: 2013-05-30 Release date: 2013-09-04 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structure of a pseudokinase-domain switch that controls oncogenic activation of Jak kinases. Nat.Struct.Mol.Biol., 20, 2013
4L00	Crystal structure of the apo Jak1 pseudokinase domain Descriptor: Tyrosine-protein kinase JAK1 Authors: Toms, A.V, Eck, M.J. Deposit date: 2013-05-30 Release date: 2013-09-04 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Structure of a pseudokinase-domain switch that controls oncogenic activation of Jak kinases. Nat.Struct.Mol.Biol., 20, 2013
4NV5	C50A mutant of Synechococcus VKOR, C2 crystal form (dehydrated) Descriptor: UBIQUINONE-10, VKORC1/thioredoxin domain protein Authors: Liu, S, Cheng, W, Fowle Grider, R, Shen, G, Li, W. Deposit date: 2013-12-04 Release date: 2014-02-12 Method: X-RAY DIFFRACTION (2.79 Å) Cite: Structures of an intramembrane vitamin K epoxide reductase homolog reveal control mechanisms for electron transfer. Nat Commun, 5, 2014
4NV2	C50A mutant of Synechococcus VKOR, C2221 crystal form Descriptor: UBIQUINONE-10, VKORC1/thioredoxin domain protein Authors: Liu, S, Cheng, W, Fowle Grider, R, Shen, G, Li, W. Deposit date: 2013-12-04 Release date: 2014-02-12 Method: X-RAY DIFFRACTION (3.61 Å) Cite: Structures of an intramembrane vitamin K epoxide reductase homolog reveal control mechanisms for electron transfer. Nat Commun, 5, 2014
4G2K	Crystal structure of the Marburg Virus GP2 ectodomain in its post-fusion conformation Descriptor: CHLORIDE ION, GLYCEROL, General control protein GCN4, ... Authors: Malashkevich, V.N, Koellhoffer, J.F, Harrison, J.S, Toro, R, Bhosle, R.C, Chandran, K, Lai, J.R, Almo, S.C. Deposit date: 2012-07-12 Release date: 2012-09-12 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Crystal Structure of the Marburg Virus GP2 Core Domain in Its Postfusion Conformation. Biochemistry, 51, 2012
4HI3	Crystal structure of dimeric R298A mutant of SARS coronavirus main protease Descriptor: 3C-like proteinase Authors: Wu, C.-G, Chou, C.-Y. Deposit date: 2012-10-11 Release date: 2013-05-01 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.09 Å) Cite: Mechanism for controlling the monomer-dimer conversion of SARS coronavirus main protease. Acta Crystallogr.,Sect.D, 69, 2013
4HU5	Oxime side-chain cross-links in the GCN4-p1 dimeric coiled coil: Linear precursor Descriptor: ACETATE ION, GLYCEROL, General control protein GCN4 Authors: Haney, C.M, Horne, W.S. Deposit date: 2012-11-02 Release date: 2013-08-21 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Oxime Side-Chain Cross-Links in an alpha-Helical Coiled-Coil Protein: Structure, Thermodynamics, and Folding-Templated Synthesis of Bicyclic Species. Chemistry, 19, 2013
4HSX	Structure of the L100F mutant of dehaloperoxidase-hemoglobin A from Amphitrite ornata with 4-bromophenol Descriptor: 4-BROMOPHENOL, Dehaloperoxidase A, GLYCEROL, ... Authors: Thompson, M.K, Plummer, A, Franzen, S. Deposit date: 2012-10-31 Release date: 2013-05-01 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.12 Å) Cite: Role of polarity of the distal pocket in the control of inhibitor binding in dehaloperoxidase-hemoglobin. Biochemistry, 52, 2013
4HSW	Structure of the L100F mutant of dehaloperoxidase-hemoglobin A from Amphitrite ornata Descriptor: Dehaloperoxidase A, GLYCEROL, PROTOPORPHYRIN IX CONTAINING FE, ... Authors: Thompson, M.K, Plummer, A, Franzen, S. Deposit date: 2012-10-31 Release date: 2013-05-01 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.22 Å) Cite: Role of polarity of the distal pocket in the control of inhibitor binding in dehaloperoxidase-hemoglobin. Biochemistry, 52, 2013
4HTM	Mechanism of CREB Recognition and Coactivation by the CREB Regulated Transcriptional Coactivator CRTC2 Descriptor: CREB-regulated transcription coactivator 2, ZINC ION Authors: Luo, Q, Viste, K, Urday-Zaa, J.C, Kumar, G.S, Tsai, W.-W, Talai, A, Mayo, K, Montminy, M, Radhakrishnan, I. Deposit date: 2012-11-01 Release date: 2012-12-05 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2 Å) Cite: Protein kinase N1, a cell inhibitor of Akt kinase, has a central role in quality control of germinal center formation Proc.Natl.Acad.Sci.USA, 2012
7QHS	S. cerevisiae CMGE nucleating origin DNA melting Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein 45, ... Authors: Lewis, J.S, Sousa, J.S, Costa, A. Deposit date: 2021-12-14 Release date: 2022-06-15 Last modified: 2022-07-06 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Mechanism of replication origin melting nucleated by CMG helicase assembly. Nature, 606, 2022
5OY5	Monomeric crystal structure of RpBphP1 photosensory core domain from the bacterium Rhodopseudomonas palustris Descriptor: BILIVERDINE IX ALPHA, BphP1 Authors: Papiz, M.Z, Bellini, D. Deposit date: 2017-09-07 Release date: 2019-02-06 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Insights into the light-induced molecular switch of the bacteriophytochrome RpBphP1 probed by SAXS, modelling and UV-Vis optical properties To Be Published
5VYG	Crystal structure of hFA9 EGF repeat with O-glucose trisaccharide Descriptor: CALCIUM ION, Coagulation factor IX, alpha-D-xylopyranose-(1-3)-alpha-D-xylopyranose-(1-3)-beta-D-glucopyranose Authors: Yu, H.J, Li, H.L. Deposit date: 2017-05-25 Release date: 2017-08-09 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.2 Å) Cite: O-Glycosylation modulates the stability of epidermal growth factor-like repeats and thereby regulates Notch trafficking J. Biol. Chem., 292, 2017
6CK3	Co-crytsal Structure of MNK2 in Complex With an Inhibitor Descriptor: (3R)-3-methyl-5-[(pyrimidin-4-yl)amino]-2,3-dihydro-1H-isoindol-1-one, CHLORIDE ION, MAP kinase-interacting serine/threonine-protein kinase 2, ... Authors: Han, Q. Deposit date: 2018-02-27 Release date: 2018-05-09 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Structure-based Design of Pyridone-Aminal eFT508 Targeting Dysregulated Translation by Selective Mitogen-activated Protein Kinase Interacting Kinases 1 and 2 (MNK1/2) Inhibition. J. Med. Chem., 61, 2018
6CJW	Crystal Structure of Mnk2-D228G in Complex With Inhibitor Descriptor: 3-(pyridin-4-yl)imidazo[1,2-b]pyridazine, MAP kinase-interacting serine/threonine-protein kinase 2, ZINC ION Authors: Han, Q. Deposit date: 2018-02-27 Release date: 2018-05-09 Method: X-RAY DIFFRACTION (3.38 Å) Cite: Structure-based Design of Pyridone-Aminal eFT508 Targeting Dysregulated Translation by Selective Mitogen-activated Protein Kinase Interacting Kinases 1 and 2 (MNK1/2) Inhibition. J. Med. Chem., 61, 2018
6CJ5	Crystal Structure of Mnk2-D228G in Complex With Inhibitor Descriptor: 3-(pyridin-3-yl)imidazo[1,2-a]pyridine-8-carboxamide, MAP kinase-interacting serine/threonine-protein kinase 2, ZINC ION Authors: Han, Q. Deposit date: 2018-02-26 Release date: 2018-05-09 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Structure-based Design of Pyridone-Aminal eFT508 Targeting Dysregulated Translation by Selective Mitogen-activated Protein Kinase Interacting Kinases 1 and 2 (MNK1/2) Inhibition. J. Med. Chem., 61, 2018
6CKI	Co-crystal structure of MNK2 in Complex With Inhibitor Descriptor: 3,3-dimethyl-6-[(pyrimidin-4-yl)amino]-2,3-dihydroimidazo[1,5-a]pyridine-1,5-dione, MAP kinase-interacting serine/threonine-protein kinase 2, ZINC ION Authors: Han, Q. Deposit date: 2018-02-28 Release date: 2018-05-09 Method: X-RAY DIFFRACTION (2.95 Å) Cite: Structure-based Design of Pyridone-Aminal eFT508 Targeting Dysregulated Translation by Selective Mitogen-activated Protein Kinase Interacting Kinases 1 and 2 (MNK1/2) Inhibition. J. Med. Chem., 61, 2018
6CJH	Co-crystal structure of MNK2 in complex with an inhibitor Descriptor: 3-phenyl-5-(pyridin-4-yl)-1H-indazole, MAP kinase-interacting serine/threonine-protein kinase 2, ZINC ION Authors: Han, Q. Deposit date: 2018-02-26 Release date: 2018-05-09 Method: X-RAY DIFFRACTION (3.6 Å) Cite: Structure-based Design of Pyridone-Aminal eFT508 Targeting Dysregulated Translation by Selective Mitogen-activated Protein Kinase Interacting Kinases 1 and 2 (MNK1/2) Inhibition. J. Med. Chem., 61, 2018
6CJE	Crystal Structure of Mnk2-D228G in complex with Inhibitor Descriptor: 4-[(9H-purin-6-yl)amino]benzamide, MAP kinase-interacting serine/threonine-protein kinase 2, ZINC ION Authors: Han, Q. Deposit date: 2018-02-26 Release date: 2018-05-09 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (3.36 Å) Cite: Structure-based Design of Pyridone-Aminal eFT508 Targeting Dysregulated Translation by Selective Mitogen-activated Protein Kinase Interacting Kinases 1 and 2 (MNK1/2) Inhibition. J. Med. Chem., 61, 2018
3UM7	Crystal structure of the human two pore domain K+ ion channel TRAAK (K2P4.1) Descriptor: POTASSIUM ION, Potassium channel subfamily K member 4 Authors: Brohawn, S.G, MacKinnon, R. Deposit date: 2011-11-12 Release date: 2012-02-08 Method: X-RAY DIFFRACTION (3.31 Å) Cite: Crystal structure of the human K2P TRAAK, a lipid- and mechano-sensitive K+ ion channel. Science, 335, 2012
4YWK	Pyrococcus furiosus MCM N-terminal domain with Zinc-binding subdomain B deleted Descriptor: Cell division control protein 21 Authors: Froelich, C.A, Enemark, E.J. Deposit date: 2015-03-20 Release date: 2015-09-23 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.55 Å) Cite: MCM ring hexamerization is a prerequisite for DNA-binding. Nucleic Acids Res., 43, 2015
4YWL	Pyrococcus furiosus MCM N-terminal domain F179A point mutant pentameric ring Descriptor: Cell division control protein 21, SULFATE ION, ZINC ION Authors: Froelich, C.A, Enemark, E.J. Deposit date: 2015-03-20 Release date: 2015-09-23 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (3.2 Å) Cite: MCM ring hexamerization is a prerequisite for DNA-binding. Nucleic Acids Res., 43, 2015
5W43	Structure of the two-component response regulator RcsB-DNA complex Descriptor: DNA (5'-D(*GP*AP*TP*TP*TP*AP*GP*GP*AP*AP*AP*AP*AP*TP*CP*TP*TP*AP*GP*AP*TP*A)-3'), DNA (5'-D(*TP*AP*TP*CP*TP*AP*AP*GP*AP*TP*TP*TP*TP*TP*CP*CP*TP*AP*AP*AP*TP*C)-3'), Transcriptional regulatory protein RcsB Authors: Filippova, E.V, Warwzak, Z, Pshenychnyi, S, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) Deposit date: 2017-06-09 Release date: 2018-03-07 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (3.15 Å) Cite: Structural Basis for DNA Recognition by the Two-Component Response Regulator RcsB. MBio, 9, 2018

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