5VYG

Crystal structure of hFA9 EGF repeat with O-glucose trisaccharide

Summary for 5VYG

Entry DOI	10.2210/pdb5vyg/pdb
Descriptor	Coagulation factor IX, alpha-D-xylopyranose-(1-3)-alpha-D-xylopyranose-(1-3)-beta-D-glucopyranose, CALCIUM ION, ... (4 entities in total)
Functional Keywords	notch regulation, egf repeat, glycosylation, transferase-hydrolase complex, transferase, hydrolase
Biological source	Homo sapiens (Human)
Total number of polymer chains	3
Total formula weight	18584.08
Authors	Yu, H.J.,Li, H.L. (deposition date: 2017-05-25, release date: 2017-08-09, Last modification date: 2023-10-04)
Primary citation	Takeuchi, H.,Yu, H.,Hao, H.,Takeuchi, M.,Ito, A.,Li, H.,Haltiwanger, R.S. O-Glycosylation modulates the stability of epidermal growth factor-like repeats and thereby regulates Notch trafficking J. Biol. Chem., 292:15964-15973, 2017 Cited by PubMed: 28729422 DOI: 10.1074/jbc.M117.800102 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation