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7YV3
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BU of 7yv3 by Molmil
genetically encoded pH sensor Lime at pH10
Descriptor: Lime
Authors:Wen, Y, Shen, Y, Campbell, R, Lemieux, M.J.
Deposit date:2022-08-18
Release date:2023-08-16
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2 Å)
Cite:Rational Engineering of an Improved Genetically Encoded pH Sensor Based on Superecliptic pHluorin.
ACS Sens, 8, 2023
7YV5
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BU of 7yv5 by Molmil
genetically encoded pH sensor Lime at pH6
Descriptor: Lime
Authors:Wen, Y, Shen, Y, Campbell, R, Lemieux, M.J.
Deposit date:2022-08-18
Release date:2023-08-16
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Rational Engineering of an Improved Genetically Encoded pH Sensor Based on Superecliptic pHluorin.
ACS Sens, 8, 2023
8IMX
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BU of 8imx by Molmil
Cryo-EM structure of GPI-T with a chimeric GPI-anchored protein
Descriptor: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Xu, Y, Li, T, Qu, Q, Li, D.
Deposit date:2023-03-07
Release date:2023-08-16
Last modified:2023-11-01
Method:ELECTRON MICROSCOPY (2.85 Å)
Cite:Structures of liganded glycosylphosphatidylinositol transamidase illuminate GPI-AP biogenesis.
Nat Commun, 14, 2023
8IMY
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BU of 8imy by Molmil
Cryo-EM structure of GPI-T (inactive mutant) with GPI and proULBP2, a proprotein substrate
Descriptor: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Li, T, Xu, Y, Qu, Q, Li, D.
Deposit date:2023-03-07
Release date:2023-08-16
Last modified:2023-11-01
Method:ELECTRON MICROSCOPY (3.22 Å)
Cite:Structures of liganded glycosylphosphatidylinositol transamidase illuminate GPI-AP biogenesis.
Nat Commun, 14, 2023
8G4E
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BU of 8g4e by Molmil
Green Fluorescence Protein imaged on a cryo-EM imaging scaffold
Descriptor: RCG-10 - Cryo-EM imaging scaffold subunit B fused to DARPin, Superfolder Green Fluorescent Protein
Authors:Castells-Graells, R, Sawaya, M.R, Yeates, T.O.
Deposit date:2023-02-09
Release date:2023-08-09
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (2.98 Å)
Cite:Cryo-EM structure determination of small therapeutic protein targets at 3 angstrom -resolution using a rigid imaging scaffold.
Proc.Natl.Acad.Sci.USA, 120, 2023
8OOC
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BU of 8ooc by Molmil
CryoEM Structure INO80core Hexasome complex Rvb core refinement state1
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Chromatin-remodeling ATPase Ino80, ...
Authors:Zhang, M, Jungblut, A, Hoffmann, T, Eustermann, S.
Deposit date:2023-04-05
Release date:2023-08-02
Method:ELECTRON MICROSCOPY (2.93 Å)
Cite:Hexasome-INO80 complex reveals structural basis of noncanonical nucleosome remodeling.
Science, 381, 2023
8AM4
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BU of 8am4 by Molmil
Cl-rsEGFP2 Long Wavelength Structure
Descriptor: Green fluorescent protein
Authors:Orr, C.M, Fadini, A, van Thor, J.
Deposit date:2022-08-02
Release date:2023-08-02
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:Serial Femtosecond Crystallography Reveals that Photoactivation in a Fluorescent Protein Proceeds via the Hula Twist Mechanism.
J.Am.Chem.Soc., 2023
8B6T
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BU of 8b6t by Molmil
X-ray structure of the interface optimized haloalkane dehalogenase HaloTag7 fusion to the green fluorescent protein GFP (ChemoG5-TMR) labeled with a chloroalkane tetramethylrhodamine fluorophore substrate
Descriptor: CHLORIDE ION, Green fluorescent protein,Haloalkane dehalogenase, [9-[2-carboxy-5-[2-[2-(6-chloranylhexoxy)ethoxy]ethylcarbamoyl]phenyl]-6-(dimethylamino)xanthen-3-ylidene]-dimethyl-azanium
Authors:Tarnawski, M, Hellweg, L, Hiblot, J.
Deposit date:2022-09-27
Release date:2023-07-26
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2 Å)
Cite:A general method for the development of multicolor biosensors with large dynamic ranges.
Nat.Chem.Biol., 19, 2023
8B6S
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BU of 8b6s by Molmil
X-ray structure of the haloalkane dehalogenase HaloTag7 fusion to the green fluorescent protein GFP (ChemoG1) labeled with a chloroalkane tetramethylrhodamine fluorophore substrate
Descriptor: CHLORIDE ION, GLYCEROL, Green fluorescent protein,Haloalkane dehalogenase, ...
Authors:Tarnawski, M, Hellweg, L, Hiblot, J.
Deposit date:2022-09-27
Release date:2023-07-26
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A general method for the development of multicolor biosensors with large dynamic ranges.
Nat.Chem.Biol., 19, 2023
8P2K
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BU of 8p2k by Molmil
Ternary complex of translating ribosome, NAC and METAP1
Descriptor: 18s rRNA, 28S rRNA, 40S ribosomal protein S11, ...
Authors:Jia, M, Jaskolowski, M, Scaiola, A, Jomaa, A, Ban, N.
Deposit date:2023-05-16
Release date:2023-07-19
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:NAC controls cotranslational N-terminal methionine excision in eukaryotes.
Science, 380, 2023
8A6O
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BU of 8a6o by Molmil
Room temperature rsEGFP2 with a chlorinated chromophore 600 fs after Photoexcitation
Descriptor: Green fluorescent protein
Authors:Fadini, A, van Thor, J.
Deposit date:2022-06-18
Release date:2023-07-19
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Serial Femtosecond Crystallography Reveals that Photoactivation in a Fluorescent Protein Proceeds via the Hula Twist Mechanism.
J.Am.Chem.Soc., 145, 2023
8A6S
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BU of 8a6s by Molmil
Room temperature rsEGFP2 with a chlorinated chromophore 1 microsecond after Photoexcitation
Descriptor: Green fluorescent protein
Authors:Fadini, A, van Thor, J.
Deposit date:2022-06-19
Release date:2023-07-19
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Serial Femtosecond Crystallography Reveals that Photoactivation in a Fluorescent Protein Proceeds via the Hula Twist Mechanism.
J.Am.Chem.Soc., 145, 2023
8A6N
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BU of 8a6n by Molmil
Room temperature rsEGFP2 with a chlorinated chromophore 300 fs after Photoexcitation
Descriptor: Green fluorescent protein
Authors:Fadini, A, van Thor, J.
Deposit date:2022-06-18
Release date:2023-07-19
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Serial Femtosecond Crystallography Reveals that Photoactivation in a Fluorescent Protein Proceeds via the Hula Twist Mechanism.
J.Am.Chem.Soc., 145, 2023
8A83
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BU of 8a83 by Molmil
rsEGFP2 with a chlorinated chromophore in the fluorescent ON-state in a crystal dehydrated after illumination
Descriptor: Green fluorescent protein, SULFATE ION
Authors:Fadini, A, van Thor, J, Chang, J.
Deposit date:2022-06-21
Release date:2023-07-19
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.81 Å)
Cite:Serial Femtosecond Crystallography Reveals that Photoactivation in a Fluorescent Protein Proceeds via the Hula Twist Mechanism.
J.Am.Chem.Soc., 145, 2023
8AHB
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BU of 8ahb by Molmil
rsEGFP2 photoswitched to its off-state at room temperature and back-switched to its on-state at 100K
Descriptor: Green fluorescent protein, SULFATE ION
Authors:Mantovanelli, A, Adam, V.
Deposit date:2022-07-21
Release date:2023-07-19
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Photophysical Studies at Cryogenic Temperature Reveal a Novel Photoswitching Mechanism of rsEGFP2.
J.Am.Chem.Soc., 145, 2023
8A6G
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BU of 8a6g by Molmil
Room temperature rsEGFP2 with a chlorinated chromophore in the non-fluorescent OFF-state
Descriptor: Green fluorescent protein
Authors:Fadini, A, van Thor, J.
Deposit date:2022-06-17
Release date:2023-07-19
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Serial Femtosecond Crystallography Reveals that Photoactivation in a Fluorescent Protein Proceeds via the Hula Twist Mechanism.
J.Am.Chem.Soc., 145, 2023
8A6P
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BU of 8a6p by Molmil
Room temperature rsEGFP2 with a chlorinated chromophore 900 fs after photoexcitation
Descriptor: Green fluorescent protein
Authors:Fadini, A, van Thor, J.
Deposit date:2022-06-18
Release date:2023-07-19
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Serial Femtosecond Crystallography Reveals that Photoactivation in a Fluorescent Protein Proceeds via the Hula Twist Mechanism.
J.Am.Chem.Soc., 145, 2023
8A6R
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BU of 8a6r by Molmil
Room temperature rsEGFP2 with a chlorinated chromophore 100 ps after Photoexcitation
Descriptor: Green fluorescent protein
Authors:Fadini, A, van Thor, J.
Deposit date:2022-06-18
Release date:2023-07-19
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Serial Femtosecond Crystallography Reveals that Photoactivation in a Fluorescent Protein Proceeds via the Hula Twist Mechanism.
J.Am.Chem.Soc., 145, 2023
8A6Q
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BU of 8a6q by Molmil
Room temperature rsEGFP2 with a chlorinated chromophore 5 ps after photoexcitation
Descriptor: Green fluorescent protein
Authors:Fadini, A, van Thor, J.
Deposit date:2022-06-18
Release date:2023-07-19
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Serial Femtosecond Crystallography Reveals that Photoactivation in a Fluorescent Protein Proceeds via the Hula Twist Mechanism.
J.Am.Chem.Soc., 145, 2023
8A7V
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BU of 8a7v by Molmil
Room temperature rsEGFP2 in its OFF-state obtained with SFX
Descriptor: Green fluorescent protein
Authors:Fadini, A, van Thor, J.
Deposit date:2022-06-21
Release date:2023-07-19
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.46 Å)
Cite:Serial Femtosecond Crystallography Reveals that Photoactivation in a Fluorescent Protein Proceeds via the Hula Twist Mechanism.
J.Am.Chem.Soc., 145, 2023
8AHA
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BU of 8aha by Molmil
rsEGFP2 photoswitched to its off-state at 100K
Descriptor: Green fluorescent protein, SULFATE ION
Authors:Mantovanelli, A, Adam, V.
Deposit date:2022-07-21
Release date:2023-07-19
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Photophysical Studies at Cryogenic Temperature Reveal a Novel Photoswitching Mechanism of rsEGFP2.
J.Am.Chem.Soc., 145, 2023
7Y77
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BU of 7y77 by Molmil
Crystal structure of rice NAL1
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Protein NARROW LEAF 1
Authors:Yan, J.J, Guan, Z.Y, Yin, P, Xiong, L.Z.
Deposit date:2022-06-21
Release date:2023-07-12
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Serine protease NAL1 exerts pleiotropic functions through degradation of TOPLESS-related corepressor in rice.
Nat.Plants, 9, 2023
8T1D
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BU of 8t1d by Molmil
Open-state cryo-EM structure of full-length human TRPV4 in complex with agonist 4a-PDD
Descriptor: (1aR,1bS,4aS,7aS,7bS,8R,9R,9aS)-9a-(decanoyloxy)-4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5-oxo-1a,1b,4,4a,5,7a,7b,8,9,9a-decahydro-1H-cyclopropa[3,4]benzo[1,2-e]azulen-9-yl decanoate, Transient receptor potential cation channel subfamily V member 4/Enhanced green fluorescent protein chimera
Authors:Talyzina, I.A, Nadezhdin, K.D, Neuberger, A, Sobolevsky, A.I.
Deposit date:2023-06-02
Release date:2023-07-05
Method:ELECTRON MICROSCOPY (3.35 Å)
Cite:Structure of human TRPV4 in complex with GTPase RhoA.
Nat Commun, 14, 2023
8T1B
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BU of 8t1b by Molmil
Cryo-EM structure of full-length human TRPV4 in apo state
Descriptor: (2R)-2-{[(4-O-hexopyranosyl-beta-D-glucopyranosyl)oxy]methyl}-4-{[(25R)-5beta,14beta,17beta-spirostan-3beta-yl]oxy}butyl 4-O-alpha-D-glucopyranosyl-beta-D-glucopyranoside, SODIUM ION, Transient receptor potential cation channel subfamily V member 4/Enhanced green fluorescent protein chimera, ...
Authors:Nadezhdin, K.D, Talyzina, I.A, Neuberger, A, Sobolevsky, A.I.
Deposit date:2023-06-02
Release date:2023-07-05
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structure of human TRPV4 in complex with GTPase RhoA.
Nat Commun, 14, 2023
8T1F
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Cryo-EM structure of full-length human TRPV4 in complex with antagonist HC-067047
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-methyl-1-[3-(morpholin-4-yl)propyl]-5-phenyl-N-[3-(trifluoromethyl)phenyl]-1H-pyrrole-3-carboxamide, Transient receptor potential cation channel subfamily V member 4/Enhanced green fluorescent protein chimera
Authors:Talyzina, I.A, Nadezhdin, K.D, Neuberger, A, Sobolevsky, A.I.
Deposit date:2023-06-02
Release date:2023-07-05
Method:ELECTRON MICROSCOPY (3.49 Å)
Cite:Structure of human TRPV4 in complex with GTPase RhoA.
Nat Commun, 14, 2023

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