PDB: 5583 resultsInfo pagesStatus searchChemie searchBIRD

---

6WI5	De novo designed protein Foldit4 Descriptor: De novo designed protein Foldit4 Authors: Bera, A.K, Koepnick, B, Boykov, A, Baker, D. Deposit date: 2020-04-08 Release date: 2020-04-22 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.83 Å) Cite: De novo design of protein logic gates. Science, 368, 2020
6MSP	De novo Designed Protein Foldit3 Descriptor: De novo Designed Protein Foldit3 Authors: Liu, G, Ishida, Y, Swapna, G.V.T, Kleinfelter, S, Koepnick, B, Baker, D, Montelione, G.T. Deposit date: 2018-10-17 Release date: 2019-06-12 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: De novo protein design by citizen scientists. Nature, 570, 2019
7M5T	Solution NMR structure of de novo designed protein 0515 Descriptor: De novo designed protein 0515 Authors: Ramelot, T.A, Hao, J, Baker, D, Montelione, G.T. Deposit date: 2021-03-24 Release date: 2021-12-15 Last modified: 2022-07-27 Method: SOLUTION NMR Cite: De novo protein design by deep network hallucination. Nature, 600, 2021
5WLJ	De Novo Design of Polynuclear Transition Metal Clusters in Helix Bundles-4EH1 Descriptor: De Novo Metal Binding Helical Bundle, ZINC ION Authors: Zhang, S.-Q, Liu, L, DeGrado, W.F. Deposit date: 2017-07-27 Release date: 2018-01-03 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.6 Å) Cite: De Novo Design of Tetranuclear Transition Metal Clusters Stabilized by Hydrogen-Bonded Networks in Helical Bundles. J. Am. Chem. Soc., 140, 2018
5KPH	Solution NMR Structure of Denovo Beta Sheet Design Protein, Northeast Structural Genomics Consortium (NESG) Target OR485 Descriptor: De novo Beta Sheet Design Protein OR485 Authors: Tang, Y, Liu, G, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) Deposit date: 2016-07-04 Release date: 2016-09-28 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: Principles for designing proteins with cavities formed by curved beta sheets. Science, 355, 2017
5KPE	Solution NMR Structure of Denovo Beta Sheet Design Protein, Northeast Structural Genomics Consortium (NESG) Target OR664 Descriptor: De novo Beta Sheet Design Protein OR664 Authors: Tang, Y, Liu, G, Baker, D, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) Deposit date: 2016-07-03 Release date: 2016-09-21 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: Principles for designing proteins with cavities formed by curved beta sheets. Science, 355, 2017
2MQ8	Solution NMR Structure of De novo designed protein LFR1 1 with ferredoxin fold, Northeast Structural Genomics Consortium (NESG) Target OR414 Descriptor: De novo designed protein LFR1 Authors: Liu, G, Lin, Y, Koga, N, Koga, R, Xiao, R, Janjua, H, Pederson, K, Acton, T.B, Kornhaber, G, Everett, J.K, Baker, D, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) Deposit date: 2014-06-12 Release date: 2014-08-20 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: Control over overall shape and size in de novo designed proteins. Proc.Natl.Acad.Sci.USA, 112, 2015
8TN6	De novo designed protein binds poly ADP ribose polymerase inhibitors (PARPi) - holo rucaparib Descriptor: De novo designed protein, Rucaparib Authors: Lu, L, DeGrado, W.F. Deposit date: 2023-08-01 Release date: 2024-04-24 Method: X-RAY DIFFRACTION (1.36 Å) Cite: De novo design of drug-binding proteins with predictable binding energy and specificity. Science, 384, 2024
8TN1	De novo designed protein binds poly ADP ribose polymerase inhibitors (PARPi) - apo Descriptor: De novo designed 4 helix bundles, SULFATE ION Authors: Lu, L, DeGrado, W.F. Deposit date: 2023-08-01 Release date: 2024-04-24 Method: X-RAY DIFFRACTION (1.61 Å) Cite: De novo design of drug-binding proteins with predictable binding energy and specificity. Science, 384, 2024
8HDU	De novo design cavitated protein without predefined topology Descriptor: De novo design cavitated protein Authors: Hu, X, Xu, Y. Deposit date: 2022-11-06 Release date: 2023-01-18 Last modified: 2024-04-24 Method: X-RAY DIFFRACTION (2.71 Å) Cite: De novo design of cavity-containing proteins with a backbone-centered neural network energy function. Structure, 32, 2024
8HDV	De novo design cavitated protein without predefined topology Descriptor: De novo design cavitated protein Authors: Hu, X, Xu, Y. Deposit date: 2022-11-06 Release date: 2023-01-18 Last modified: 2024-04-24 Method: X-RAY DIFFRACTION (2.65 Å) Cite: De novo design of cavity-containing proteins with a backbone-centered neural network energy function. Structure, 32, 2024
5YXI	Designed protein dRafX6 Descriptor: Designed protein dRafX6 Authors: Liu, R. Deposit date: 2017-12-05 Release date: 2018-12-05 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: De novo sequence redesign of a functional Ras-binding domain globally inverted the surface charge distribution and led to extreme thermostability. Biotechnol.Bioeng., 118, 2021
7SKN	De novo synthetic protein DIG8-CC (tetragonal space group) Descriptor: De novo synthetic protein DIG8-CC Authors: Mendes, S.R, Eckhard, U, Marcos, E, Gomis-Ruth, F.X. Deposit date: 2021-10-21 Release date: 2022-10-12 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.3 Å) Cite: De novo design of immunoglobulin-like domains Nat Commun, 13, 2022
7SKP	De novo synthetic protein DIG14 (tetragonal space group) Descriptor: De novo synthetic protein DIG14 Authors: Mendes, S.R, Eckhard, U, Marcos, E, Gomis-Ruth, F.X. Deposit date: 2021-10-21 Release date: 2022-10-12 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.5 Å) Cite: De novo design of immunoglobulin-like domains Nat Commun, 13, 2022
7SKO	De novo synthetic protein DIG8-CC (orthogonal space group) Descriptor: De novo synthetic protein DIG8-CC, MAGNESIUM ION Authors: Mendes, S.R, Eckhard, U, Marcos, E, Gomis-Ruth, F.X. Deposit date: 2021-10-21 Release date: 2022-10-12 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.05 Å) Cite: De novo design of immunoglobulin-like domains Nat Commun, 13, 2022
8TND	De novo designed protein binds poly ADP ribose polymerase inhibitors (PARPi) - holo veliparib Descriptor: (2R)-2-(7-carbamoyl-1H-benzimidazol-2-yl)-2-methylpyrrolidinium, De novo designed protein, SULFATE ION Authors: Lu, L, DeGrado, W.F. Deposit date: 2023-08-01 Release date: 2024-04-24 Method: X-RAY DIFFRACTION (1.29 Å) Cite: De novo design of drug-binding proteins with predictable binding energy and specificity. Science, 384, 2024
8TNB	De novo designed protein binds poly ADP ribose polymerase inhibitors (PARPi) - holo mefuparib Descriptor: 5-fluoro-2-{4-[(methylamino)methyl]phenyl}-1-benzofuran-7-carboxamide, De novo designed protein Authors: Lu, L, DeGrado, W.F. Deposit date: 2023-08-01 Release date: 2024-04-24 Method: X-RAY DIFFRACTION (1.4 Å) Cite: De novo design of drug-binding proteins with predictable binding energy and specificity. Science, 384, 2024
8TNC	De novo designed protein binds poly ADP ribose polymerase inhibitors (PARPi) - holo niraparib Descriptor: 2-{4-[(3S)-piperidin-3-yl]phenyl}-2H-indazole-7-carboxamide, De novo designed protein Authors: Lu, L, DeGrado, W.F. Deposit date: 2023-08-01 Release date: 2024-04-24 Method: X-RAY DIFFRACTION (1.4 Å) Cite: De novo design of drug-binding proteins with predictable binding energy and specificity. Science, 384, 2024
6MRR	De novo designed protein Foldit1 Descriptor: Foldit1 Authors: Koepnick, B, Bick, M.J, Estep, R.D, Kleinfelter, S, Wei, L, Baker, D. Deposit date: 2018-10-15 Release date: 2019-06-12 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.18 Å) Cite: De novo protein design by citizen scientists. Nature, 570, 2019
6MRS	De novo designed protein Peak6 Descriptor: Peak6, SULFATE ION Authors: Koepnick, B, Boykov, A, Baker, D. Deposit date: 2018-10-15 Release date: 2019-06-12 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.541 Å) Cite: De novo protein design by citizen scientists. Nature, 570, 2019
7CBC	Crystal structure of a de novo designed switch protein caging a hemagglutinin binder Descriptor: De novo designed switch protein caging a hemagglutinin binder (sCageHA267_1S), ETHANOL Authors: Lee, H, Oh, B.-H, Baker, D. Deposit date: 2020-06-11 Release date: 2020-12-23 Last modified: 2021-03-31 Method: X-RAY DIFFRACTION (1.99 Å) Cite: De novo design of modular and tunable protein biosensors. Nature, 591, 2021
1PBZ	DE NOVO DESIGNED PEPTIDE-METALLOPORPHYRIN COMPLEX, SOLUTION STRUCTURE Descriptor: COPROPORPHYRIN I CONTAINING CO(III), De novo designed cyclic peptide Authors: Wang, J, Rosenblatt, M.M, Suslick, K.S. Deposit date: 2003-05-15 Release date: 2003-12-09 Last modified: 2022-02-23 Method: SOLUTION NMR Cite: De novo designed cyclic-peptide heme complexes Proc.Natl.Acad.Sci.USA, 100, 2003
6X1K	Solution NMR structure of de novo designed TMB2.3 Descriptor: De novo designed transmembrane beta-barrel TMB2.3 Authors: Liang, B, Vorobieva, A.A, Chow, C.M, Baker, D, Tamm, L.K. Deposit date: 2020-05-19 Release date: 2021-02-17 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: De novo design of transmembrane beta barrels. Science, 371, 2021
6E5C	Solution NMR structure of a de novo designed double-stranded beta-helix Descriptor: De novo beta protein Authors: Marcos, E, Chidyausiku, T.M, McShan, A, Evangelidis, T, Nerli, S, Sgourakis, N, Tripsianes, K, Baker, D. Deposit date: 2018-07-19 Release date: 2018-11-07 Last modified: 2024-05-01 Method: SOLUTION NMR Cite: De novo design of a non-local beta-sheet protein with high stability and accuracy. Nat. Struct. Mol. Biol., 25, 2018
7UWY	NMR solution structure of the De novo designed small beta-barrel protein 29_bp_sh3 Descriptor: De novo designed small beta-barrel protein 29_bp_sh3 Authors: Peterson, F.C, Kim, D.E, Jensen, D.R, Saleem, A, Chow, C.M, Volkman, B.F, Baker, D. Deposit date: 2022-05-04 Release date: 2023-03-22 Method: SOLUTION NMR Cite: De novo design of small beta barrel proteins. Proc.Natl.Acad.Sci.USA, 120, 2023

 

12345678910111213141516>