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6B48
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BU of 6b48 by Molmil
Cryo-EM structure of Type I-F CRISPR crRNA-guided Csy surveillance complex with bound anti-CRISPR protein AcrF10
Descriptor: Anti-CRISPR protein AcrF10, CRISPR-associated endonuclease Cas6/Csy4, CRISPR-associated protein Csy1, ...
Authors:Guo, T.W, Bartesaghi, A, Yang, H, Falconieri, V, Rao, P, Merk, A, Fox, T, Earl, L, Patel, D.J, Subramaniam, S.
Deposit date:2017-09-25
Release date:2017-10-18
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Cryo-EM Structures Reveal Mechanism and Inhibition of DNA Targeting by a CRISPR-Cas Surveillance Complex.
Cell, 171, 2017
6C3R
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BU of 6c3r by Molmil
Cricket paralysis virus RNAi suppressor protein CrPV-1A
Descriptor: Cricket paralysis virus 1A protein
Authors:Nayak, A, Kim, D.Y, Andino, R, Gross, J.
Deposit date:2018-01-10
Release date:2018-10-17
Last modified:2019-12-18
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:A Viral Protein Restricts Drosophila RNAi Immunity by Regulating Argonaute Activity and Stability.
Cell Host Microbe, 24, 2018
2Y35
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BU of 2y35 by Molmil
Crystal structure of Xrn1-substrate complex
Descriptor: DT11 (5'-D(*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP)-3', LD22664P, MAGNESIUM ION
Authors:Jinek, M, Coyle, S.M, Doudna, J.A.
Deposit date:2010-12-18
Release date:2011-03-16
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Coupled 5' Nucleotide Recognition and Processivity in Xrn1-Mediated Mrna Decay.
Mol.Cell, 41, 2011
2XFM
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BU of 2xfm by Molmil
Complex structure of the MIWI Paz domain bound to methylated single stranded RNA
Descriptor: 5'-R(*AP*CP*CP*GP*AP*CP*UP*(OMU)P)-3', PIWI-LIKE PROTEIN 1
Authors:Simon, B, Kirkpatrick, J.P, Eckhardt, S, Sehr, P, Andrade-Navarro, M.A, Pillai, R.S, Carlomagno, T.
Deposit date:2010-05-27
Release date:2011-01-26
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Recognition of 2'-O-Methylated 3'-End of Pirna by the Paz Domain of a Piwi Protein.
Structure, 19, 2011
4ZT9
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BU of 4zt9 by Molmil
Nuclease-inactive Streptococcus pyogenes Cas9 (D10A/H840A, dCas9) in complex with single-guide RNA at 3.1 Angstrom resolution
Descriptor: CRISPR-associated endonuclease Cas9, single-guide RNA
Authors:Jiang, F, Doudna, J.A.
Deposit date:2015-05-14
Release date:2015-07-08
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:A Cas9-guide RNA complex preorganized for target DNA recognition.
Science, 348, 2015
4ZT0
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BU of 4zt0 by Molmil
Crystal structure of catalytically-active Streptococcus pyogenes Cas9 in complex with single-guide RNA at 2.9 Angstrom resolution
Descriptor: CRISPR-associated endonuclease Cas9, single-guide RNA
Authors:Jiang, F, Doudna, J.A.
Deposit date:2015-05-14
Release date:2015-07-08
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:A Cas9-guide RNA complex preorganized for target DNA recognition.
Science, 348, 2015
6LFZ
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BU of 6lfz by Molmil
Crystal structure of SbCGTb in complex with UDPG
Descriptor: SbCGTb, URIDINE-5'-DIPHOSPHATE-GLUCOSE
Authors:Gao, H.M, Yun, C.H.
Deposit date:2019-12-04
Release date:2020-11-18
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.866 Å)
Cite:Dissection of the general two-step di- C -glycosylation pathway for the biosynthesis of (iso)schaftosides in higher plants.
Proc.Natl.Acad.Sci.USA, 117, 2020
6LF6
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BU of 6lf6 by Molmil
Crystal structure of ZmCGTa in complex with UDP
Descriptor: UDP-glycosyltransferase 708A6, URIDINE-5'-DIPHOSPHATE
Authors:Gao, H.M, Yun, C.H.
Deposit date:2019-11-29
Release date:2020-11-18
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.044 Å)
Cite:Dissection of the general two-step di- C -glycosylation pathway for the biosynthesis of (iso)schaftosides in higher plants.
Proc.Natl.Acad.Sci.USA, 117, 2020
6LG1
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BU of 6lg1 by Molmil
Crystal structure of LpCGTa in complex with UDP
Descriptor: LpCGTa, URIDINE-5'-DIPHOSPHATE
Authors:Gao, H.M, Yun, C.H.
Deposit date:2019-12-04
Release date:2020-11-18
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.047 Å)
Cite:Dissection of the general two-step di- C -glycosylation pathway for the biosynthesis of (iso)schaftosides in higher plants.
Proc.Natl.Acad.Sci.USA, 117, 2020
6LG0
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BU of 6lg0 by Molmil
Crystal structure of SbCGTa in complex with UDP
Descriptor: SbCGTa, URIDINE-5'-DIPHOSPHATE
Authors:Gao, H.M, Yun, C.H.
Deposit date:2019-12-04
Release date:2020-11-18
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.998 Å)
Cite:Dissection of the general two-step di- C -glycosylation pathway for the biosynthesis of (iso)schaftosides in higher plants.
Proc.Natl.Acad.Sci.USA, 117, 2020
6LFN
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BU of 6lfn by Molmil
Crystal structure of LpCGTb
Descriptor: LpCGTb, PHOSPHATE ION
Authors:Gao, H.M, Yun, C.H.
Deposit date:2019-12-03
Release date:2020-11-18
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.395 Å)
Cite:Dissection of the general two-step di- C -glycosylation pathway for the biosynthesis of (iso)schaftosides in higher plants.
Proc.Natl.Acad.Sci.USA, 117, 2020
3WTD
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BU of 3wtd by Molmil
Structure of PAXX
Descriptor: Uncharacterized protein C9orf142
Authors:Ochi, T, Blundell, T.L.
Deposit date:2014-04-09
Release date:2015-01-21
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:DNA repair. PAXX, a paralog of XRCC4 and XLF, interacts with Ku to promote DNA double-strand break repair.
Science, 347, 2015
3WTF
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BU of 3wtf by Molmil
Structure of PAXX
Descriptor: Uncharacterized protein C9orf142
Authors:Ochi, T, Blundell, T.L.
Deposit date:2014-04-09
Release date:2015-01-21
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3.451 Å)
Cite:DNA repair. PAXX, a paralog of XRCC4 and XLF, interacts with Ku to promote DNA double-strand break repair.
Science, 347, 2015
6O1O
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BU of 6o1o by Molmil
Cryo-EM structure of the T. thermophilus Csm complex bound to target ssRNA
Descriptor: Csm1, Csm2, Csm3, ...
Authors:Liu, J.J, Liu, T.Y.
Deposit date:2019-02-21
Release date:2019-07-10
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Target preference of Type III-A CRISPR-Cas complexes at the transcription bubble.
Nat Commun, 10, 2019
3BBF
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BU of 3bbf by Molmil
Crystal structure of the NM23-H2 transcription factor complex with GDP
Descriptor: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Weichsel, A, Montfort, W.R.
Deposit date:2007-11-09
Release date:2008-09-23
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:NM23-H2 may play an indirect role in transcriptional activation of c-myc gene expression but does not cleave the nuclease hypersensitive element III1.
Mol.Cancer Ther., 8, 2009
3BBB
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BU of 3bbb by Molmil
Crystal structure of the NM23-H2 transcription factor complex with dinucleotide d(AG)
Descriptor: DNA (5'-D(*AP*G)-3'), Nucleoside diphosphate kinase B
Authors:Weichsel, A, Montfort, W.R.
Deposit date:2007-11-09
Release date:2008-09-23
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:NM23-H2 may play an indirect role in transcriptional activation of c-myc gene expression but does not cleave the nuclease hypersensitive element III1.
Mol.Cancer Ther., 8, 2009
3BBC
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BU of 3bbc by Molmil
Crystal structure of R88A mutant of the NM23-H2 transcription factor
Descriptor: Nucleoside diphosphate kinase B
Authors:Weichsel, A, Montfort, W.R.
Deposit date:2007-11-09
Release date:2008-09-23
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:NM23-H2 may play an indirect role in transcriptional activation of c-myc gene expression but does not cleave the nuclease hypersensitive element III1.
Mol.Cancer Ther., 8, 2009
2GUT
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BU of 2gut by Molmil
Solution structure of the trans-activation domain of the human co-activator ARC105
Descriptor: ARC/MEDIATOR, Positive cofactor 2 glutamine/Q-rich-associated protein
Authors:Vought, B.W, Jim Sun, Z.-Y, Hyberts, S.G, Wagner, G, Naar, A.M.
Deposit date:2006-05-01
Release date:2006-08-08
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:An ARC/Mediator subunit required for SREBP control of cholesterol and lipid homeostasis.
Nature, 442, 2006
2HNS
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BU of 2hns by Molmil
Structure of the AAGU tetraloop
Descriptor: 5'-R(*GP*GP*CP*GP*UP*GP*AP*UP*CP*AP*AP*GP*UP*GP*AP*UP*CP*GP*CP*GP*CP*C)-3'
Authors:Gaudin, C, Fourmy, F, Yoshizawa, S.
Deposit date:2006-07-13
Release date:2006-10-31
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Structure of an AAGU Tetraloop and its Contribution to Substrate Selection by yeast RNase III.
J.Mol.Biol., 363, 2006
1W22
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BU of 1w22 by Molmil
Crystal structure of inhibited human HDAC8
Descriptor: HISTONE DEACETYLASE 8, N-HYDROXY-4-(METHYL{[5-(2-PYRIDINYL)-2-THIENYL]SULFONYL}AMINO)BENZAMIDE, POTASSIUM ION, ...
Authors:Vannini, A, Volpari, C, Caroli Casavola, E, Di Marco, S.
Deposit date:2004-06-25
Release date:2004-09-24
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structure of a Eukaryotic Zn-Dependent Histone Deacetylase,Human Hdac8,Complexed with a Hydroxamic Acid Inhibitor
Proc.Natl.Acad.Sci.USA, 101, 2004
1W3B
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BU of 1w3b by Molmil
The superhelical TPR domain of O-linked GlcNAc transferase reveals structural similarities to importin alpha.
Descriptor: CALCIUM ION, UDP-N-ACETYLGLUCOSAMINE--PEPTIDE N-ACETYLGLUCOSAMINYLTRANSFERASE 110
Authors:Jinek, M, Rehwinkel, J, Lazarus, B.D, Izaurralde, E, Hanover, J.A, Conti, E.
Deposit date:2004-07-14
Release date:2004-09-09
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:The Superhelical Tpr-Repeat Domain of O-Linked Glcnac Transferase Exhibits Structural Similarities to Importin Alpha
Nat.Struct.Mol.Biol., 11, 2004
5O8M
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BU of 5o8m by Molmil
Crystal structure of the MmI1 YTH domain
Descriptor: GLYCEROL, YTH domain-containing protein mmi1
Authors:Brettschneider, J, Verdel, A, Kadlec, J.
Deposit date:2017-06-13
Release date:2018-04-25
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Selective termination of lncRNA transcription promotes heterochromatin silencing and cell differentiation.
EMBO J., 36, 2017
3FQI
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BU of 3fqi by Molmil
Crystal Structure of the Mouse Dom3Z
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, MAGNESIUM ION, Protein Dom3Z
Authors:Xiang, S, Tong, L.
Deposit date:2009-01-07
Release date:2009-02-03
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.013 Å)
Cite:Structure and function of the 5'-->3' exoribonuclease Rat1 and its activating partner Rai1.
Nature, 458, 2009
3FQG
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BU of 3fqg by Molmil
Crystal Structure of the S. pombe Rai1
Descriptor: MAGNESIUM ION, Protein din1
Authors:Xiang, S, Tong, L.
Deposit date:2009-01-07
Release date:2009-02-03
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure and function of the 5'-->3' exoribonuclease Rat1 and its activating partner Rai1.
Nature, 458, 2009
3FQJ
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BU of 3fqj by Molmil
Crystal Structure of the Mouse Dom3Z in Complex with GDP
Descriptor: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Protein Dom3Z
Authors:Xiang, S, Tong, L.
Deposit date:2009-01-07
Release date:2009-02-03
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.623 Å)
Cite:Structure and function of the 5'-->3' exoribonuclease Rat1 and its activating partner Rai1.
Nature, 458, 2009

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