1GIH
| HUMAN CYCLIN DEPENDENT KINASE 2 COMPLEXED WITH THE CDK4 INHIBITOR | Descriptor: | 1-(5-OXO-2,3,5,9B-TETRAHYDRO-1H-PYRROLO[2,1-A]ISOINDOL-9-YL)-3-PYRIDIN-2-YL-UREA, CELL DIVISION PROTEIN KINASE 2 | Authors: | Ikuta, M, Nishimura, S. | Deposit date: | 2001-02-06 | Release date: | 2002-02-06 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystallographic approach to identification of cyclin-dependent kinase 4 (CDK4)-specific inhibitors by using CDK4 mimic CDK2 protein. J.Biol.Chem., 276, 2001
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1JVP
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2HXI
| Structural Genomics, the crystal structure of a putative transcriptional regulator from Streptomyces coelicolor A3(2) | Descriptor: | Putative transcriptional regulator | Authors: | Tan, K, Xu, X, Zheng, H, Savchenko, A, Edwards, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2006-08-03 | Release date: | 2006-09-05 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | The crystal structure of a putative transcriptional regulator TetR from Streptomyces coelicolor A3(2) To be Published
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2HXO
| Structure of the transcriptional regulator SCO7222, a TetR from Streptomyces coelicolor | Descriptor: | Putative TetR-family transcriptional regulator | Authors: | Singer, A.U, Skarina, T, Zhang, R.G, Onopriyenko, O, Edwards, A.M, Joachimiak, A, Savchenko, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2006-08-03 | Release date: | 2006-08-22 | Last modified: | 2017-10-18 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structure of the transcriptional regulator SCO7222, a TetR from Streptomyces coelicolor To be Published
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6O22
| Structure of Asf1-H3:H4-Rtt109-Vps75 histone chaperone-lysine acetyltransferase complex with the histone substrate. | Descriptor: | Histone H3.2, Histone H4, Histone acetyltransferase RTT109, ... | Authors: | Danilenko, N, Carlomagno, T, Kirkpatrick, J.P. | Deposit date: | 2019-02-22 | Release date: | 2019-07-31 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR, SOLUTION SCATTERING | Cite: | Histone chaperone exploits intrinsic disorder to switch acetylation specificity. Nat Commun, 10, 2019
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4X60
| Crystal structure of PRMT5:MEP50 with EPZ015666 and sinefungin | Descriptor: | GLYCEROL, Methylosome protein 50, N-[(2S)-3-(3,4-dihydroisoquinolin-2(1H)-yl)-2-hydroxypropyl]-6-(oxetan-3-ylamino)pyrimidine-4-carboxamide, ... | Authors: | Boriack-Sjodin, P.A. | Deposit date: | 2014-12-06 | Release date: | 2015-04-22 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | A selective inhibitor of PRMT5 with in vivo and in vitro potency in MCL models. Nat.Chem.Biol., 11, 2015
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2KT0
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2DMU
| Solution structure of the homeobox domain of Homeobox protein goosecoid | Descriptor: | Homeobox protein goosecoid | Authors: | Ohnishi, S, Sato, M, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2006-04-24 | Release date: | 2006-10-24 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the homeobox domain of Homeobox protein goosecoid To be Published
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2DMT
| Solution structure of the homeobox domain of Homeobox protein BarH-like 1 | Descriptor: | Homeobox protein BarH-like 1 | Authors: | Ohnishi, S, Yoneyama, M, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2006-04-24 | Release date: | 2006-10-24 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the homeobox domain of Homeobox protein BarH-like 1 To be Published
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5MMM
| Structure of the 70S chloroplast ribosome | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein 2, ... | Authors: | Bieri, P, Leibundgut, M, Saurer, M, Boehringer, D, Ban, N. | Deposit date: | 2016-12-11 | Release date: | 2017-01-11 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | The complete structure of the chloroplast 70S ribosome in complex with translation factor pY. EMBO J., 36, 2017
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2L7F
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8DJ6
| Sliding-clamp-ImuB peptide | Descriptor: | ACETATE ION, Beta sliding clamp, FORMIC ACID, ... | Authors: | Kapur, M.K, Gray, O.J, Honzatko, R.H, Nelson, S.N. | Deposit date: | 2022-06-30 | Release date: | 2023-07-26 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Interaction of sliding clamp with mycobacterial polymerases To Be Published
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5MLC
| Cryo-EM structure of the spinach chloroplast ribosome reveals the location of plastid-specific ribosomal proteins and extensions | Descriptor: | 23S ribosomal RNA, chloroplastic, 4.8S ribosomal RNA, ... | Authors: | Graf, M, Arenz, S, Huter, P, Doenhoefer, A, Novacek, J, Wilson, D.N. | Deposit date: | 2016-12-06 | Release date: | 2016-12-28 | Last modified: | 2019-12-11 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Cryo-EM structure of the spinach chloroplast ribosome reveals the location of plastid-specific ribosomal proteins and extensions. Nucleic Acids Res., 45, 2017
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6EKJ
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5MMI
| Structure of the large subunit of the chloroplast ribosome | Descriptor: | 23S ribosomal RNA, 4.5S ribosomal RNA, 50S ribosomal protein 6, ... | Authors: | Bieri, P, Leibundgut, M, Saurer, M, Boehringer, D, Ban, N. | Deposit date: | 2016-12-10 | Release date: | 2017-01-11 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | The complete structure of the chloroplast 70S ribosome in complex with translation factor pY. EMBO J., 36, 2017
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5MSF
| MS2 PROTEIN CAPSID/RNA COMPLEX | Descriptor: | 5'-R(*CP*CP*GP*GP*AP*GP*GP*AP*UP*CP*AP*CP*CP*AP*CP*GP*GP*G)-3', MS2 PROTEIN CAPSID | Authors: | Rowsell, S, Stonehouse, N.J, Convery, M.A, Adams, C.J, Ellington, A.D, Hirao, I, Peabody, D.S, Stockley, P.G, Phillips, S.E.V. | Deposit date: | 1998-05-15 | Release date: | 1998-11-11 | Last modified: | 2023-08-02 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal structures of a series of RNA aptamers complexed to the same protein target. Nat.Struct.Biol., 5, 1998
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6EKL
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7BL4
| in vitro reconstituted 50S-ObgE-GMPPNP-RsfS particle | Descriptor: | 23S ribosomal RNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ... | Authors: | Hilal, T, Nikolay, R, Spahn, C.M.T. | Deposit date: | 2021-01-18 | Release date: | 2021-05-12 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (2.4 Å) | Cite: | Snapshots of native pre-50S ribosomes reveal a biogenesis factor network and evolutionary specialization. Mol.Cell, 81, 2021
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7BL2
| pre-50S-ObgE particle state 1 | Descriptor: | 23S ribosomal RNA, 50S ribosomal protein L11, 50S ribosomal protein L13, ... | Authors: | Hilal, T, Nikolay, R, Schmidt, S, Spahn, C.M.T. | Deposit date: | 2021-01-18 | Release date: | 2021-05-12 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Snapshots of native pre-50S ribosomes reveal a biogenesis factor network and evolutionary specialization. Mol.Cell, 81, 2021
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7BL6
| 50S-ObgE-GMPPNP particle | Descriptor: | 23S ribosomal RNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ... | Authors: | Hilal, T, Nikolay, R, Schmidt, S, Spahn, C.M.T. | Deposit date: | 2021-01-18 | Release date: | 2021-05-12 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Snapshots of native pre-50S ribosomes reveal a biogenesis factor network and evolutionary specialization. Mol.Cell, 81, 2021
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7BL5
| pre-50S-ObgE particle | Descriptor: | 23S ribosomal RNA, 50S ribosomal protein L10, 50S ribosomal protein L11, ... | Authors: | Hilal, T, Nikolay, R, Spahn, C.M.T, Schmidt, S. | Deposit date: | 2021-01-18 | Release date: | 2021-05-12 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Snapshots of native pre-50S ribosomes reveal a biogenesis factor network and evolutionary specialization. Mol.Cell, 81, 2021
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7BL3
| pre-50S-ObgE particle state 2 | Descriptor: | 23S ribosomal RNA, 50S ribosomal protein L11, 50S ribosomal protein L13, ... | Authors: | Hilal, T, Nikolay, R, Spahn, C.M.T. | Deposit date: | 2021-01-18 | Release date: | 2021-05-12 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Snapshots of native pre-50S ribosomes reveal a biogenesis factor network and evolutionary specialization. Mol.Cell, 81, 2021
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5NDK
| Crystal structure of aminoglycoside TC007 co-crystallized with 70S ribosome from Thermus thermophilus, three tRNAs and mRNA | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Prokhorova, I, Djumagulov, M, Urzhumtsev, A, Yusupov, M, Yusupova, G. | Deposit date: | 2017-03-08 | Release date: | 2017-12-13 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Aminoglycoside interactions and impacts on the eukaryotic ribosome. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5AKA
| EM structure of ribosome-SRP-FtsY complex in closed state | Descriptor: | 23S ribosomal RNA, 4.5S ribosomal RNA, 50S RIBOSOMAL PROTEIN L11, ... | Authors: | von Loeffelholz, O, Jiang, Q, Ariosa, A, Karuppasamy, M, Huard, K, Berger, I, Shan, S, Schaffitzel, C. | Deposit date: | 2015-03-03 | Release date: | 2015-03-25 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (5.7 Å) | Cite: | Ribosome-Srp-Ftsy Cotranslational Targeting Complex in the Closed State. Proc.Natl.Acad.Sci.USA, 112, 2015
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5NJT
| Structure of the Bacillus subtilis hibernating 100S ribosome reveals the basis for 70S dimerization. | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Beckert, B, Abdelshahid, M, Schaefer, H, Steinchen, W, Arenz, S, Berninghausen, O, Beckmann, R, Bange, G, Turgay, K, Wilson, D.N. | Deposit date: | 2017-03-29 | Release date: | 2017-06-14 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structure of the Bacillus subtilis hibernating 100S ribosome reveals the basis for 70S dimerization. EMBO J., 36, 2017
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