6G5I
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![BU of 6g5i by Molmil](/molmil-images/mine/6g5i) | Cryo-EM structure of a late human pre-40S ribosomal subunit - State R | Descriptor: | 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | Authors: | Ameismeier, M, Cheng, J, Berninghausen, O, Beckmann, R. | Deposit date: | 2018-03-29 | Release date: | 2018-06-06 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Visualizing late states of human 40S ribosomal subunit maturation. Nature, 558, 2018
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4TYH
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![BU of 4tyh by Molmil](/molmil-images/mine/4tyh) | Ternary complex of P38 and MK2 with a P38 inhibitor | Descriptor: | MAP kinase-activated protein kinase 2, Mitogen-activated protein kinase 14, N-[5-(dimethylsulfamoyl)-2-methylphenyl]-1-phenyl-5-propyl-1H-pyrazole-4-carboxamide | Authors: | Cumming, J.G, Debreczeni, J.E, Edfeldt, F, Evertsson, F, Harrison, M, Holdgate, G, James, M, Lamont, S, Oldham, K, Sullivan, J.E, Wells, S. | Deposit date: | 2014-07-08 | Release date: | 2015-07-22 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Discovery of substrate selective, ATP-competitive P38 alpha MAP kinase inhibitors To Be Published
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6S0K
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![BU of 6s0k by Molmil](/molmil-images/mine/6s0k) | Ribosome nascent chain in complex with SecA | Descriptor: | 23S ribosomal RNA, 50S ribosomal protein L10, 50S ribosomal protein L11, ... | Authors: | Jomaa, A, Wang, S, Shan, S, Ban, N. | Deposit date: | 2019-06-17 | Release date: | 2019-10-09 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | The molecular mechanism of cotranslational membrane protein recognition and targeting by SecA. Nat.Struct.Mol.Biol., 26, 2019
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3VFZ
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![BU of 3vfz by Molmil](/molmil-images/mine/3vfz) | |
6G5H
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![BU of 6g5h by Molmil](/molmil-images/mine/6g5h) | Cryo-EM structure of a late human pre-40S ribosomal subunit - Mature | Descriptor: | 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | Authors: | Ameismeier, M, Cheng, J, Berninghausen, O, Beckmann, R. | Deposit date: | 2018-03-29 | Release date: | 2018-06-06 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Visualizing late states of human 40S ribosomal subunit maturation. Nature, 558, 2018
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6G51
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![BU of 6g51 by Molmil](/molmil-images/mine/6g51) | Cryo-EM structure of a late human pre-40S ribosomal subunit - State D | Descriptor: | 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | Authors: | Ameismeier, M, Cheng, J, Berninghausen, O, Beckmann, R. | Deposit date: | 2018-03-28 | Release date: | 2018-06-06 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Visualizing late states of human 40S ribosomal subunit maturation. Nature, 558, 2018
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3ZMS
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![BU of 3zms by Molmil](/molmil-images/mine/3zms) | LSD1-CoREST in complex with INSM1 peptide | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, INSULINOMA-ASSOCIATED PROTEIN 1, LYSINE-SPECIFIC HISTONE DEMETHYLASE 1A, ... | Authors: | Tortorici, M, Borrello, M.T, Tardugno, M, Chiarelli, L.R, Pilotto, S, Ciossani, G, Vellore, N.A, Cowan, J, O'Connell, M, Mai, A, Baron, R, Ganesan, A, Mattevi, A. | Deposit date: | 2013-02-12 | Release date: | 2013-06-12 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.96 Å) | Cite: | Protein Recognition by Small Peptide Reversible Inhibitors of the Chromatin-Modifying Lsd1/Corest Lysine Demethylase. Acs Chem.Biol., 8, 2013
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4Q2U
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9BJK
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![BU of 9bjk by Molmil](/molmil-images/mine/9bjk) | Inactive mu opioid receptor bound to Nb6, naloxone and NAM | Descriptor: | Mu-type opioid receptor, Naloxone, Nalpha-[({(1M)-1-[5-(benzyloxy)pyridin-3-yl]naphthalen-2-yl}sulfanyl)acetyl]-3-methoxy-N,4-dimethyl-L-phenylalaninamide, ... | Authors: | O'Brien, E.S, Wang, H, Kaavya Krishna, K, Zhang, C, Kobilka, B.K. | Deposit date: | 2024-04-25 | Release date: | 2024-07-17 | Last modified: | 2024-08-14 | Method: | ELECTRON MICROSCOPY (3.26 Å) | Cite: | A mu-opioid receptor modulator that works cooperatively with naloxone. Nature, 631, 2024
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8Y7M
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![BU of 8y7m by Molmil](/molmil-images/mine/8y7m) | FluPol-NS2 complex (local refinement) | Descriptor: | Nuclear export protein, Polymerase acidic protein, Polymerase basic protein 2, ... | Authors: | Peng, Q, Sun, J.Q. | Deposit date: | 2024-02-04 | Release date: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | NS2 stabilizes polymerase hexamer to regulate transcription-replication switch of influenza A virus To Be Published
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9FXN
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8ZJ2
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![BU of 8zj2 by Molmil](/molmil-images/mine/8zj2) | Cryo-EM structure of the RhoG/DOCK5/ELMO1/Rac1 complex | Descriptor: | Dedicator of cytokinesis protein 5, Engulfment and cell motility protein 1, GUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Kukimoto-Niino, M, Katsura, K, Ishizuka-Katsura, Y, Mishima-Tsumagari, C, Yonemochi, M, Inoue, M, Nakagawa, R, Kaushik, R, Zhang, K.Y.J, Shirouzu, M. | Deposit date: | 2024-05-14 | Release date: | 2024-06-26 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (4.66 Å) | Cite: | RhoG facilitates a conformational transition in the guanine nucleotide exchange factor complex DOCK5/ELMO1 to an open state. J.Biol.Chem., 300, 2024
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8Y7O
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![BU of 8y7o by Molmil](/molmil-images/mine/8y7o) | FluPol-NS2 complex (hexamer) | Descriptor: | Nuclear export protein, Polymerase acidic protein, Polymerase basic protein 2, ... | Authors: | Peng, Q, Sun, J.Q. | Deposit date: | 2024-02-04 | Release date: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | NS2 stabilizes polymerase hexamer to regulate transcription-replication switch of influenza A virus To Be Published
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8YSB
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![BU of 8ysb by Molmil](/molmil-images/mine/8ysb) | Crystal structure of DynA1, a putative monoxygenase from Mivromonospora chersina. | Descriptor: | Predicted ester cyclase | Authors: | Yan, X.F, Huang, H.W, Gao, Y.G, Liang, Z.X. | Deposit date: | 2024-03-22 | Release date: | 2024-09-04 | Last modified: | 2024-09-11 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | An Enzymatic Oxidation Cascade Converts delta-Thiolactone Anthracene to Anthraquinone in the Biosynthesis of Anthraquinone-Fused Enediynes. Jacs Au, 4, 2024
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7LQ4
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![BU of 7lq4 by Molmil](/molmil-images/mine/7lq4) | Rr (RsiG)2-(c-di-GMP)2-WhiG complex | Descriptor: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), RsiG, WhiG | Authors: | Schumacher, M.A, Brennan, R.G. | Deposit date: | 2021-02-12 | Release date: | 2021-07-14 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Evolution of a sigma-(c-di-GMP)-anti-sigma switch. Proc.Natl.Acad.Sci.USA, 118, 2021
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2DCE
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![BU of 2dce by Molmil](/molmil-images/mine/2dce) | Solution structure of the SWIRM domain of human KIAA1915 protein | Descriptor: | KIAA1915 protein | Authors: | Yoneyama, M, Tochio, N, Umehara, T, Koshiba, S, Inoue, M, Tanaka, A, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2006-01-06 | Release date: | 2006-07-06 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Structural and Functional Differences of SWIRM Domain Subtypes J.Mol.Biol., 369, 2007
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5WG6
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![BU of 5wg6 by Molmil](/molmil-images/mine/5wg6) | Human Polycomb Repressive Complex 2 in complex with GSK126 inhibitor | Descriptor: | 1-[(2S)-butan-2-yl]-N-[(4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl]-3-methyl-6-[6-(piperazin-1-yl)pyridin-3-yl]-1H-indole-4-carboxamide, Histone-lysine N-methyltransferase EZH2,Polycomb protein SUZ12 (E.C.2.1.1.43) chimera, Polycomb protein EED, ... | Authors: | Bratkowski, M.A, Liu, X. | Deposit date: | 2017-07-13 | Release date: | 2018-06-27 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (3.901 Å) | Cite: | An Evolutionarily Conserved Structural Platform for PRC2 Inhibition by a Class of Ezh2 Inhibitors. Sci Rep, 8, 2018
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2DQL
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2YRQ
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![BU of 2yrq by Molmil](/molmil-images/mine/2yrq) | Solution structure of the tandem HMG box domain from Human High mobility group protein B1 | Descriptor: | High mobility group protein B1 | Authors: | Tomizawa, T, Koshiba, S, Watanabe, S, Harada, T, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-04-02 | Release date: | 2008-02-12 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the tandem HMG box domain from Human High mobility group protein B1 To be Published
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3C7J
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![BU of 3c7j by Molmil](/molmil-images/mine/3c7j) | Crystal structure of transcriptional regulator (GntR family member) from Pseudomonas syringae pv. tomato str. DC3000 | Descriptor: | NICKEL (II) ION, Transcriptional regulator, GntR family | Authors: | Nocek, B, Sather, A, Gu, M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2008-02-07 | Release date: | 2008-02-26 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure of transcriptional regulator (GntR family member) from Pseudomonas syringae pv. tomato str. DC3000. To be Published
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3CCY
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3CDL
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![BU of 3cdl by Molmil](/molmil-images/mine/3cdl) | |
1QVT
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![BU of 1qvt by Molmil](/molmil-images/mine/1qvt) | |
3CWR
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![BU of 3cwr by Molmil](/molmil-images/mine/3cwr) | |
3C07
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![BU of 3c07 by Molmil](/molmil-images/mine/3c07) | Crystal structure of a TetR family transcriptional regulator from Streptomyces coelicolor A3(2) | Descriptor: | Putative tetR-family transcriptional regulator, SULFATE ION | Authors: | Tan, K, Xu, X, Zheng, H, Savchenko, A, Edwards, A.M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2008-01-18 | Release date: | 2008-02-05 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | The structure of a TetR family transcriptional regulator from Streptomyces coelicolor A3(2). To be Published
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