1UWR
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![BU of 1uwr by Molmil](/molmil-images/mine/1uwr) | Structure of beta-glycosidase from Sulfolobus solfataricus in complex with 2-deoxy-2-fluoro-galactose | Descriptor: | 2-deoxy-2-fluoro-alpha-D-galactopyranose, ACETATE ION, BETA-GALACTOSIDASE | Authors: | Gloster, T.M, Roberts, S, Ducros, V.M.-A, Perugino, G, Rossi, M, Hoos, R, Moracci, M, Vasella, A, Davies, G.J. | Deposit date: | 2004-02-11 | Release date: | 2004-05-20 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.14 Å) | Cite: | Structural Studies of the Beta-Glycosidase from Sulfolobus Solfataricus in Complex with Covalently and Noncovalently Bound Inhibitors. Biochemistry, 43, 2004
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4WLU
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![BU of 4wlu by Molmil](/molmil-images/mine/4wlu) | |
1UXQ
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![BU of 1uxq by Molmil](/molmil-images/mine/1uxq) | Structural basis for allosteric regulation and substrate specificity of the non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase (GAPN) from Thermoproteus tenax | Descriptor: | 1-O-phosphono-alpha-D-glucopyranose, GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE (NADP+), NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | Authors: | Lorentzen, E, Hensel, R, Pohl, E. | Deposit date: | 2004-03-01 | Release date: | 2004-08-05 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural Basis of Allosteric Regulation and Substrate Specificity of the Non-Phosphorylating Glyceraldehyde 3-Phosphate Dehydrogenase from Thermoproteus Tenax J.Mol.Biol., 341, 2004
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1GAD
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![BU of 1gad by Molmil](/molmil-images/mine/1gad) | COMPARISON OF THE STRUCTURES OF WILD TYPE AND A N313T MUTANT OF ESCHERICHIA COLI GLYCERALDEHYDE 3-PHOSPHATE DEHYDROGENASES: IMPLICATION FOR NAD BINDING AND COOPERATIVITY | Descriptor: | D-GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | Authors: | Duee, E, Olivier-Deyris, L, Fanchon, E, Corbier, C, Branlant, G, Dideberg, O. | Deposit date: | 1995-10-24 | Release date: | 1996-03-08 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Comparison of the structures of wild-type and a N313T mutant of Escherichia coli glyceraldehyde 3-phosphate dehydrogenases: implication for NAD binding and cooperativity. J.Mol.Biol., 257, 1996
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3OX2
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![BU of 3ox2 by Molmil](/molmil-images/mine/3ox2) | X-ray Structural study of quinone reductase II inhibition by compounds with micromolar to nanomolar range IC50 values | Descriptor: | 2-hydroxy-8,9-dimethoxy-6H-isoindolo[2,1-a]indol-6-one, FLAVIN-ADENINE DINUCLEOTIDE, Ribosyldihydronicotinamide dehydrogenase [quinone], ... | Authors: | Pegan, S.D, Sturdy, M, Mesecar, A.D. | Deposit date: | 2010-09-21 | Release date: | 2011-05-25 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.41 Å) | Cite: | X-ray structural studies of quinone reductase 2 nanomolar range inhibitors. Protein Sci., 20, 2011
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1UJN
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![BU of 1ujn by Molmil](/molmil-images/mine/1ujn) | Crystal structure of dehydroquinate synthase from Thermus thermophilus HB8 | Descriptor: | dehydroquinate synthase | Authors: | Sugahara, M, Yokoyama, S, Kuramitsu, S, Miyano, M, Kunishima, N, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2003-08-06 | Release date: | 2003-09-02 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of dehydroquinate synthase from Thermus thermophilus HB8 showing functional importance of the dimeric state. Proteins, 58, 2005
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7F5T
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![BU of 7f5t by Molmil](/molmil-images/mine/7f5t) | Drosophila P5CS filament with glutamate | Descriptor: | Delta-1-pyrroline-5-carboxylate synthase, GLUTAMIC ACID | Authors: | Liu, J.L, Zhong, J, Guo, C.J, Zhou, X. | Deposit date: | 2021-06-22 | Release date: | 2022-05-18 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Structural basis of dynamic P5CS filaments. Elife, 11, 2022
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1GB3
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![BU of 1gb3 by Molmil](/molmil-images/mine/1gb3) | CRYSTAL STRUCTURE OF MUTANT HUMAN LYSOZYME SUBSTITUTED AT THE SURFACE POSITIONS | Descriptor: | LYSOZYME, SODIUM ION | Authors: | Funahashi, J, Takano, K, Yamagata, Y, Yutani, K. | Deposit date: | 2000-06-26 | Release date: | 2000-07-27 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Role of surface hydrophobic residues in the conformational stability of human lysozyme at three different positions. Biochemistry, 39, 2000
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1UJM
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1GB8
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![BU of 1gb8 by Molmil](/molmil-images/mine/1gb8) | CRYSTAL STRUCTURE OF MUTANT HUMAN LYSOZYME SUBSTITUTED AT THE SURFACE POSITIONS | Descriptor: | LYSOZYME, SODIUM ION | Authors: | Funahashi, J, Takano, K, Yamagata, Y, Yutani, K. | Deposit date: | 2000-06-26 | Release date: | 2000-07-27 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Role of surface hydrophobic residues in the conformational stability of human lysozyme at three different positions. Biochemistry, 39, 2000
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7EUL
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1V3H
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![BU of 1v3h by Molmil](/molmil-images/mine/1v3h) | The roles of Glu186 and Glu380 in the catalytic reaction of soybean beta-amylase | Descriptor: | Beta-amylase, SULFATE ION, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | Authors: | Kang, Y.N, Adachi, M, Utsumi, S, Mikami, B. | Deposit date: | 2003-11-02 | Release date: | 2004-06-22 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | The Roles of Glu186 and Glu380 in the Catalytic Reaction of Soybean beta-Amylase. J.Mol.Biol., 339, 2004
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1GBZ
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![BU of 1gbz by Molmil](/molmil-images/mine/1gbz) | CRYSTAL STRUCTURE OF MUTANT HUMAN LYSOZYME SUBSTITUTED AT THE SURFACE POSITIONS | Descriptor: | LYSOZYME, SODIUM ION | Authors: | Funahashi, J, Takano, K, Yamagata, Y, Yutani, K. | Deposit date: | 2000-06-26 | Release date: | 2000-07-27 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Role of surface hydrophobic residues in the conformational stability of human lysozyme at three different positions. Biochemistry, 39, 2000
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1GB0
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![BU of 1gb0 by Molmil](/molmil-images/mine/1gb0) | CRYSTAL STRUCTURE OF MUTANT HUMAN LYSOZYME SUBSTITUTED AT THE SURFACE POSITIONS | Descriptor: | LYSOZYME, SODIUM ION | Authors: | Funahashi, J, Takano, K, Yamagata, Y, Yutani, K. | Deposit date: | 2000-06-26 | Release date: | 2000-07-27 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Role of surface hydrophobic residues in the conformational stability of human lysozyme at three different positions. Biochemistry, 39, 2000
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1V3V
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![BU of 1v3v by Molmil](/molmil-images/mine/1v3v) | Crystal structure of leukotriene B4 12-hydroxydehydrogenase/15-oxo-prostaglandin 13-reductase complexed with NADP and 15-oxo-PGE2 | Descriptor: | (5E,13E)-11-HYDROXY-9,15-DIOXOPROSTA-5,13-DIEN-1-OIC ACID, CHLORIDE ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | Authors: | Hori, T, Yokomizo, T, Ago, H, Sugahara, M, Ueno, G, Yamamoto, M, Kumasaka, T, Shimizu, T, Miyano, M, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2003-11-06 | Release date: | 2004-07-13 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural basis of leukotriene B4 12-hydroxydehydrogenase/15-Oxo-prostaglandin 13-reductase catalytic mechanism and a possible Src homology 3 domain binding loop J.Biol.Chem., 279, 2004
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1GED
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![BU of 1ged by Molmil](/molmil-images/mine/1ged) | A positive charge route for the access of nadh to heme formed in the distal heme pocket of cytochrome p450nor | Descriptor: | BROMIDE ION, CYTOCHROME P450 55A1, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Kudo, T, Takaya, N, Park, S.-Y, Shiro, Y, Shoun, H. | Deposit date: | 2000-11-02 | Release date: | 2000-11-22 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | A positively charged cluster formed in the heme-distal pocket of cytochrome P450nor is essential for interaction with NADH J.Biol.Chem., 276, 2001
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5K0Z
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![BU of 5k0z by Molmil](/molmil-images/mine/5k0z) | Cryo-EM structure of lactate dehydrogenase (LDH) in inhibitor-bound state | Descriptor: | L-lactate dehydrogenase B chain | Authors: | Merk, A, Bartesaghi, A, Banerjee, S, Falconieri, V, Rao, P, Earl, L, Milne, J, Subramaniam, S. | Deposit date: | 2016-05-17 | Release date: | 2016-06-08 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Breaking Cryo-EM Resolution Barriers to Facilitate Drug Discovery. Cell, 165, 2016
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1V6X
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![BU of 1v6x by Molmil](/molmil-images/mine/1v6x) | Crystal Structure Of Xylanase From Streptomyces Olivaceoviridis E-86 Complexed With 3(3)-4-O-methyl-alpha-D-glucuronosyl-xylotriose | Descriptor: | 4-O-methyl-alpha-D-glucopyranuronic acid-(1-2)-beta-D-xylopyranose-(1-4)-beta-D-xylopyranose-(1-4)-beta-D-xylopyranose, ENDO-1,4-BETA-D-XYLANASE, beta-D-xylopyranose, ... | Authors: | Fujimoto, Z, Kaneko, S, Kuno, A, Kobayashi, H, Kusakabe, I, Mizuno, H. | Deposit date: | 2003-12-04 | Release date: | 2004-04-27 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structures of decorated xylooligosaccharides bound to a family 10 xylanase from Streptomyces olivaceoviridis E-86 J.Biol.Chem., 279, 2004
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1GG5
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![BU of 1gg5 by Molmil](/molmil-images/mine/1gg5) | CRYSTAL STRUCTURE OF A COMPLEX OF HUMAN NAD[P]H-QUINONE OXIDOREDUCTASE AND A CHEMOTHERAPEUTIC DRUG (E09) AT 2.5 A RESOLUTION | Descriptor: | 3-HYDROXYMETHYL-5-AZIRIDINYL-1METHYL-2-[1H-INDOLE-4,7-DIONE]-PROPANOL, FLAVIN-ADENINE DINUCLEOTIDE, NAD(P)H DEHYDROGENASE [QUINONE] 1 | Authors: | Faig, M, Bianchet, M.A, Winski, S, Hargreaves, R, Moody, C.J, Hudnott, A.R, Ross, D, Amzel, L.M. | Deposit date: | 2000-07-12 | Release date: | 2001-09-12 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure-based development of anticancer drugs: complexes of NAD(P)H:quinone oxidoreductase 1 with chemotherapeutic quinones. Structure, 9, 2001
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1GFA
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![BU of 1gfa by Molmil](/molmil-images/mine/1gfa) | CRYSTAL STRUCTURE OF MUTANT HUMAN LYSOZYME SUBSTITUTED AT THE SURFACE POSITIONS | Descriptor: | LYSOZYME, SODIUM ION | Authors: | Funahashi, J, Takano, K, Yamagata, Y, Yutani, K. | Deposit date: | 2000-12-04 | Release date: | 2000-12-20 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Positive contribution of hydration structure on the surface of human lysozyme to the conformational stability. J.Biol.Chem., 277, 2002
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1GFK
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![BU of 1gfk by Molmil](/molmil-images/mine/1gfk) | CRYSTAL STRUCTURE OF MUTANT HUMAN LYSOZYME SUBSTITUTED AT THE SURFACE POSITIONS | Descriptor: | LYSOZYME, SODIUM ION | Authors: | Funahashi, J, Takano, K, Yamagata, Y, Yutani, K. | Deposit date: | 2000-12-04 | Release date: | 2000-12-20 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Positive contribution of hydration structure on the surface of human lysozyme to the conformational stability. J.Biol.Chem., 277, 2002
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5K2S
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![BU of 5k2s by Molmil](/molmil-images/mine/5k2s) | Lysozyme with nano particles | Descriptor: | Lysozyme C | Authors: | Ko, S, Choe, J. | Deposit date: | 2016-05-19 | Release date: | 2017-05-31 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Crystal structure of lysozyme with nano particles To Be Published
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1GFU
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![BU of 1gfu by Molmil](/molmil-images/mine/1gfu) | CRYSTAL STRUCTURE OF MUTANT HUMAN LYSOZYME SUBSTITUTED AT THE SURFACE POSITIONS | Descriptor: | LYSOZYME, SODIUM ION | Authors: | Funahashi, J, Takano, K, Yamagata, Y, Yutani, K. | Deposit date: | 2000-12-04 | Release date: | 2000-12-27 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Positive contribution of hydration structure on the surface of human lysozyme to the conformational stability. J.Biol.Chem., 277, 2002
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7EUK
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4LDO
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![BU of 4ldo by Molmil](/molmil-images/mine/4ldo) | Structure of beta2 adrenoceptor bound to adrenaline and an engineered nanobody | Descriptor: | (2S)-2,3-dihydroxypropyl (7Z)-tetradec-7-enoate, Camelid Antibody Fragment, L-EPINEPHRINE, ... | Authors: | Ring, A.M, Manglik, A, Kruse, A.C, Enos, M.D, Weis, W.I, Garcia, K.C, Kobilka, B.K. | Deposit date: | 2013-06-24 | Release date: | 2013-09-25 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Adrenaline-activated structure of beta 2-adrenoceptor stabilized by an engineered nanobody. Nature, 502, 2013
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