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1V3V

Crystal structure of leukotriene B4 12-hydroxydehydrogenase/15-oxo-prostaglandin 13-reductase complexed with NADP and 15-oxo-PGE2

Summary for 1V3V
Entry DOI10.2210/pdb1v3v/pdb
Related1V3T 1V3U
Descriptorleukotriene b4 12-hydroxydehydrogenase/prostaglandin 15-keto reductase, CHLORIDE ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... (5 entities in total)
Functional Keywordsrossmann fold, riken structural genomics/proteomics initiative, rsgi, structural genomics, oxidoreductase
Biological sourceCavia porcellus (domestic guinea pig)
Cellular locationCytoplasm (By similarity): Q9EQZ5
Total number of polymer chains2
Total formula weight74864.37
Authors
Hori, T.,Yokomizo, T.,Ago, H.,Sugahara, M.,Ueno, G.,Yamamoto, M.,Kumasaka, T.,Shimizu, T.,Miyano, M.,RIKEN Structural Genomics/Proteomics Initiative (RSGI) (deposition date: 2003-11-06, release date: 2004-07-13, Last modification date: 2023-12-27)
Primary citationHori, T.,Yokomizo, T.,Ago, H.,Sugahara, M.,Ueno, G.,Yamamoto, M.,Kumasaka, T.,Shimizu, T.,Miyano, M.
Structural basis of leukotriene B4 12-hydroxydehydrogenase/15-Oxo-prostaglandin 13-reductase catalytic mechanism and a possible Src homology 3 domain binding loop
J.Biol.Chem., 279:22615-22623, 2004
Cited by
PubMed: 15007077
DOI: 10.1074/jbc.M312655200
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2 Å)
Structure validation

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