1V3V
Crystal structure of leukotriene B4 12-hydroxydehydrogenase/15-oxo-prostaglandin 13-reductase complexed with NADP and 15-oxo-PGE2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | leukotriene b4 12-hydroxydehydrogenase/prostaglandin 15-keto reductase | polymer | 333 | 36232.0 | 2 | UniProt (Q9EQZ5) Pfam (PF16884) Pfam (PF00107) | Cavia porcellus (domestic guinea pig) | leukotriene B4 12-hydroxydehydrogenase/15-oxo-prostaglandin 13-reductase |
| 2 | C, D, E, H, I... (A, B) | CHLORIDE ION | non-polymer | 35.5 | 6 | Chemie (CL) PubChem (312) | |||
| 3 | F, K (A, B) | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 2 | Chemie (NAP) PubChem (5885) PubChem (46936685) PubChem (4412) PubChem (90473931) PubChem (91972139) PubChem (145946263) PubChem (153311489) PubChem (174001641) PubChem (71717786) PubChem (165382010) | |||
| 4 | G, L (A, B) | (5E,13E)-11-HYDROXY-9,15-DIOXOPROSTA-5,13-DIEN-1-OIC ACID | non-polymer | 350.4 | 2 | Chemie (5OP) PubChem (5353288) PubChem (10405620) PubChem (13746629) PubChem (21158735) PubChem (46937058) PubChem (53477750) PubChem (1441) PubChem (160126) PubChem (51523121) PubChem (5280719) PubChem (98043988) PubChem (54523897) PubChem (57355765) PubChem (16061134) PubChem (71434124) PubChem (71684388) PubChem (71775497) PubChem (92450255) PubChem (98043989) PubChem (98043990) PubChem (124351385) PubChem (124351417) PubChem (137348384) PubChem (155293413) PubChem (156358933) PubChem (156681956) PubChem (162996772) PubChem (168313592) PubChem (171042199) | |||
| 5 | M, N (A, B) | water | water | 18.0 | 945 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 329 (UniProt: Q9EQZ5)
| PDB | External Database | Details |
|---|---|---|
| Ser -4 | - | cloning artifact |
| Pro -3 | - | cloning artifact |
| Glu -2 | - | cloning artifact |
| Phe -1 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 72463.9 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 2400.4 | |
| All* | Total formula weight | 74864.4 |
