1V3V
Crystal structure of leukotriene B4 12-hydroxydehydrogenase/15-oxo-prostaglandin 13-reductase complexed with NADP and 15-oxo-PGE2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | leukotriene b4 12-hydroxydehydrogenase/prostaglandin 15-keto reductase | polymer | 333 | 36232.0 | 2 | UniProt (Q9EQZ5) Pfam (PF16884) Pfam (PF00107) | Cavia porcellus (domestic guinea pig) | leukotriene B4 12-hydroxydehydrogenase/15-oxo-prostaglandin 13-reductase |
| 2 | C, D, E, H, I... (A, B) | CHLORIDE ION | non-polymer | 35.5 | 6 | Chemie (CL) | |||
| 3 | F, K (A, B) | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 2 | Chemie (NAP) | |||
| 4 | G, L (A, B) | (5E,13E)-11-HYDROXY-9,15-DIOXOPROSTA-5,13-DIEN-1-OIC ACID | non-polymer | 350.4 | 2 | Chemie (5OP) | |||
| 5 | M, N (A, B) | water | water | 18.0 | 945 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 329 (UniProt: Q9EQZ5)
| PDB | External Database | Details |
|---|---|---|
| Ser -4 | - | cloning artifact |
| Pro -3 | - | cloning artifact |
| Glu -2 | - | cloning artifact |
| Phe -1 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 72463.9 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 2400.4 | |
| All* | Total formula weight | 74864.4 |
