1V3V
Crystal structure of leukotriene B4 12-hydroxydehydrogenase/15-oxo-prostaglandin 13-reductase complexed with NADP and 15-oxo-PGE2
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | leukotriene b4 12-hydroxydehydrogenase/prostaglandin 15-keto reductase | polymer | 333 | 36232.0 | 2 | UniProt (Q9EQZ5) Pfam (PF16884) Pfam (PF00107) In PDB | Cavia porcellus (domestic guinea pig) | leukotriene B4 12-hydroxydehydrogenase/15-oxo-prostaglandin 13-reductase |
2 | A, B | CHLORIDE ION | non-polymer | 35.5 | 6 | Chemie (CL) | |||
3 | A, B | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 2 | Chemie (NAP) | |||
4 | A, B | (5E,13E)-11-HYDROXY-9,15-DIOXOPROSTA-5,13-DIEN-1-OIC ACID | non-polymer | 350.4 | 2 | Chemie (5OP) | |||
5 | water | water | 18.0 | 945 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 329 (UniProt: Q9EQZ5)
PDB | External Database | Details |
---|---|---|
Ser -4 | - | cloning artifact |
Pro -3 | - | cloning artifact |
Glu -2 | - | cloning artifact |
Phe -1 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 72463.9 | |
Non-Polymers* | Number of molecules | 10 |
Total formula weight | 2400.4 | |
All* | Total formula weight | 74864.4 |