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7DXQ
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BU of 7dxq by Molmil
Crystal Structure of Cyanobacterial Circadian Clock Protein KaiC
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Circadian clock protein kinase KaiC, MAGNESIUM ION
Authors:Furuike, Y, Akiyama, S.
Deposit date:2021-01-20
Release date:2022-04-27
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Elucidation of master allostery essential for circadian clock oscillation in cyanobacteria.
Sci Adv, 8, 2022
7DY2
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BU of 7dy2 by Molmil
Crystal Structure of Cyanobacterial Circadian Clock Protein KaiC
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Circadian clock protein kinase KaiC, ...
Authors:Furuike, Y, Akiyama, S.
Deposit date:2021-01-20
Release date:2022-04-27
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.04 Å)
Cite:Elucidation of master allostery essential for circadian clock oscillation in cyanobacteria.
Sci Adv, 8, 2022
7DYE
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BU of 7dye by Molmil
Crystal Structure of Cyanobacterial Circadian Clock Protein KaiC
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Circadian clock protein kinase KaiC, MAGNESIUM ION
Authors:Furuike, Y, Akiyama, S.
Deposit date:2021-01-21
Release date:2022-05-18
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Regulation mechanisms of the dual ATPase in KaiC.
Proc.Natl.Acad.Sci.USA, 119, 2022
7DY1
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BU of 7dy1 by Molmil
Crystal Structure of Cyanobacterial Circadian Clock Protein KaiC
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Circadian clock protein kinase KaiC, MAGNESIUM ION
Authors:Furuike, Y, Akiyama, S.
Deposit date:2021-01-20
Release date:2022-05-18
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Regulation mechanisms of the dual ATPase in KaiC.
Proc.Natl.Acad.Sci.USA, 119, 2022
7E20
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BU of 7e20 by Molmil
Cryo EM structure of a K+-bound Na+,K+-ATPase in the E2 state
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Guo, Y.Y, Zhang, Y.Y, Yan, R.H, Huang, B.D, Ye, F.F, Wu, L.S, Chi, X.M, Zhou, Q.
Deposit date:2021-02-04
Release date:2022-06-15
Last modified:2022-07-20
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Cryo-EM structures of recombinant human sodium-potassium pump determined in three different states.
Nat Commun, 13, 2022
1UGD
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BU of 1ugd by Molmil
HUMAN CARBONIC ANHYDRASE II[HCAII] (E.C.4.2.1.1) MUTANT WITH ALA 65 REPLACED BY SER (A65S)
Descriptor: CARBONIC ANHYDRASE II, ZINC ION
Authors:Scolnick, L.R, Christianson, D.W.
Deposit date:1996-07-24
Release date:1997-01-27
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:X-ray crystallographic studies of alanine-65 variants of carbonic anhydrase II reveal the structural basis of compromised proton transfer in catalysis.
Biochemistry, 35, 1996
7E21
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BU of 7e21 by Molmil
Cryo EM structure of a Na+-bound Na+,K+-ATPase in the E1 state with ATP-gamma-S
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Guo, Y.Y, Zhang, Y.Y, Yan, R.H, Huang, B.D, Ye, F.F, Wu, L.S, Chi, X.M, Zhou, Q.
Deposit date:2021-02-04
Release date:2022-06-15
Last modified:2022-07-20
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Cryo-EM structures of recombinant human sodium-potassium pump determined in three different states.
Nat Commun, 13, 2022
7E1Z
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BU of 7e1z by Molmil
Cryo EM structure of a Na+-bound Na+,K+-ATPase in the E1 state
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Guo, Y.Y, Zhang, Y.Y, Yan, R.H, Huang, B.D, Ye, F.F, Wu, L.S, Chi, X.M, Zhou, Q.
Deposit date:2021-02-04
Release date:2022-06-15
Last modified:2022-07-20
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Cryo-EM structures of recombinant human sodium-potassium pump determined in three different states.
Nat Commun, 13, 2022
1TVU
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BU of 1tvu by Molmil
CONTRIBUTIONS OF ORIENTATION AND HYDROGEN BONDING TO CATALYSIS IN ASN-229 MUTANTS OF THYMIDYLATE SYNTHASE
Descriptor: 10-PROPARGYL-5,8-DIDEAZAFOLIC ACID, 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, THYMIDYLATE SYNTHASE
Authors:Finer-Moore, J, Stroud, R.M.
Deposit date:1997-09-17
Release date:1998-01-28
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Contributions of orientation and hydrogen bonding to catalysis in Asn229 mutants of thymidylate synthase.
J.Mol.Biol., 276, 1998
1TOE
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BU of 1toe by Molmil
Unliganded structure of Hexamutant + A293D mutant of E. coli aspartate aminotransferase
Descriptor: Aspartate aminotransferase, SULFATE ION
Authors:Chow, M.A, McElroy, K.E, Corbett, K.D, Berger, J.M, Kirsch, J.F.
Deposit date:2004-06-14
Release date:2004-10-05
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2 Å)
Cite:Narrowing substrate specificity in a directly evolved enzyme: the A293D mutant of aspartate aminotransferase
Biochemistry, 43, 2004
1R74
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BU of 1r74 by Molmil
Crystal Structure of Human Glycine N-Methyltransferase
Descriptor: BETA-MERCAPTOETHANOL, CITRIC ACID, Glycine N-methyltransferase
Authors:Pakhomova, S, Luka, Z, Wagner, C, Newcomer, M.E.
Deposit date:2003-10-17
Release date:2004-09-21
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Glycine N-methyltransferases: a comparison of the crystal structures and kinetic properties of recombinant human, mouse and rat enzymes.
Proteins, 57, 2004
1RDQ
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BU of 1rdq by Molmil
Hydrolysis of ATP in the crystal of Y204A mutant of cAMP-dependent protein kinase
Descriptor: (4R)-2-METHYLPENTANE-2,4-DIOL, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Yang, J, Ten Eyck, L.F, Xuong, N.H, Taylor, S.S.
Deposit date:2003-11-05
Release date:2004-04-13
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.26 Å)
Cite:Crystal Structure of a cAMP-dependent Protein Kinase Mutant at 1.26A: New Insights into the Catalytic Mechanism.
J.Mol.Biol., 336, 2004
7FJM
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BU of 7fjm by Molmil
Cryo EM structure of lysosomal ATPase
Descriptor: Polyamine-transporting ATPase 13A2
Authors:Zhang, S.S.
Deposit date:2021-08-04
Release date:2023-03-08
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Cryo-EM structures and transport mechanism of human P5B type ATPase ATP13A2.
Cell Discov, 7, 2021
1REE
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BU of 1ree by Molmil
ENDO-1,4-BETA-XYLANASE II COMPLEX WITH 3,4-EPOXYBUTYL-BETA-D-XYLOSIDE
Descriptor: (3S)-3-hydroxybutyl beta-D-xylopyranoside, BENZOIC ACID, ENDO-1,4-BETA-XYLANASE II
Authors:Rouvinen, J, Havukainen, R, Torronen, A.
Deposit date:1995-12-21
Release date:1997-01-11
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Covalent binding of three epoxyalkyl xylosides to the active site of endo-1,4-xylanase II from Trichoderma reesei.
Biochemistry, 35, 1996
1REJ
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BU of 1rej by Molmil
Crystal structure of cAMP-dependent protein kinase complexed with balanol analog 1
Descriptor: 3-[(4-HYDROXYBENZOYL)AMINO]AZEPAN-4-YL 4-HYDROXYBENZOATE, cAMP-dependent protein kinase, alpha-catalytic subunit
Authors:Akamine, P, Madhusudan, Brunton, L.L, Ou, H.D, Canaves, J.M, Xuong, N.H, Taylor, S.S.
Deposit date:2003-11-06
Release date:2004-02-24
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Balanol analogues probe specificity determinants and the conformational malleability of the cyclic 3',5'-adenosine monophosphate-dependent protein kinase catalytic subunit
Biochemistry, 43, 2004
7EPB
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BU of 7epb by Molmil
Cryo-EM structure of LY354740-bound mGlu2 homodimer
Descriptor: (1S,2S,5R,6S)-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylic acid, Anti-RON nanobody, Metabotropic glutamate receptor 2
Authors:Du, J, Wang, D, Fan, H, Tai, L, Lin, S, Han, S, Sun, F, Wu, B, Zhao, Q.
Deposit date:2021-04-26
Release date:2021-06-23
Last modified:2021-07-07
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structures of human mGlu2 and mGlu7 homo- and heterodimers.
Nature, 594, 2021
7EPC
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BU of 7epc by Molmil
Cryo-EM structure of inactive mGlu7 homodimer
Descriptor: Isoform 3 of Metabotropic glutamate receptor 7
Authors:Du, J, Wang, D, Fan, H, Tai, L, Lin, S, Han, S, Sun, F, Wu, B, Zhao, Q.
Deposit date:2021-04-26
Release date:2021-06-23
Last modified:2021-07-07
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structures of human mGlu2 and mGlu7 homo- and heterodimers.
Nature, 594, 2021
7DX4
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BU of 7dx4 by Molmil
The structure of FC08 Fab-hA.CE2-RBD complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, Heavy chain of FC08 Fab, ...
Authors:Cao, L, Wang, X.
Deposit date:2021-01-18
Release date:2021-04-21
Last modified:2022-02-23
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:A proof of concept for neutralizing antibody-guided vaccine design against SARS-CoV-2.
Natl Sci Rev, 8, 2021
7EFD
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BU of 7efd by Molmil
1.77 A cryo-EM structure of Streptavidin using first 40 frames (corresponding to about 40 e/A^2 total dose)
Descriptor: BIOTIN, Streptavidin
Authors:Hiraizumi, M, Yamashita, K, Nishizawa, T, Kotecha, A, Nureki, O.
Deposit date:2021-03-21
Release date:2021-04-28
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (1.77 Å)
Cite:1.77 A cryo-EM structure of Streptavidin using first 40 frames (corresponding to about 40e/A^2 total dose)
To Be Published
7EFC
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BU of 7efc by Molmil
1.70 A cryo-EM structure of streptavidin
Descriptor: BIOTIN, Streptavidin
Authors:Hiraizumi, M, Yamashita, K, Nishizawa, T, Kotecha, A, Nureki, O.
Deposit date:2021-03-21
Release date:2021-04-28
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (1.7 Å)
Cite:1.70 A cryo-EM structure of streptavidin using all frames (corresponding to 70 e/A^2 total dose)
To Be Published
1ROV
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BU of 1rov by Molmil
Lipoxygenase-3 Treated with Cumene Hydroperoxide
Descriptor: FE (III) ION, Seed lipoxygenase-3
Authors:Vahedi-Faridi, A, Brault, P.A, Shah, P, Kim, Y.W, Dunham, W.R, Funk, M.O.
Deposit date:2003-12-02
Release date:2004-03-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Interaction between non-heme iron of lipoxygenases and cumene hydroperoxide: basis for enzyme activation, inactivation, and inhibition
J.Am.Chem.Soc., 126, 2004
7E80
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BU of 7e80 by Molmil
Cryo-EM structure of the flagellar rod with hook and export apparatus from Salmonella
Descriptor: Flagellar MS ring L1, Flagellar MS ring L2, Flagellar basal body rod protein FlgB, ...
Authors:Tan, J.X, Chang, S.H, Wang, X.F, Xu, C.H, Zhou, Y, Zhang, X, Zhu, Y.Q.
Deposit date:2021-02-28
Release date:2021-04-28
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.67 Å)
Cite:Structural basis of assembly and torque transmission of the bacterial flagellar motor.
Cell, 184, 2021
1R3L
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BU of 1r3l by Molmil
potassium channel KcsA-Fab complex in Cs+
Descriptor: Antibody Fab fragment heavy chain, Antibody Fab fragment light chain, CESIUM ION, ...
Authors:Zhou, Y, MacKinnon, R.
Deposit date:2003-10-02
Release date:2003-11-25
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:The occupancy of ions in the K+ selectivity filter: Charge balance and coupling of ion binding to a protein conformational change underlie high conduction rates
J.Mol.Biol., 333, 2003
1R51
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BU of 1r51 by Molmil
URATE OXIDASE FROM ASPERGILLUS FLAVUS COMPLEXED WITH ITS INHIBITOR 8-AZAXANTHIN
Descriptor: 8-AZAXANTHINE, CYSTEINE, Uricase
Authors:Prange, T, Retailleau, P, Colloc'h, N.
Deposit date:2003-10-09
Release date:2004-03-02
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Complexed and ligand-free high-resolution structures of urate oxidase (Uox) from Aspergillus flavus: a reassignment of the active-site binding mode.
Acta Crystallogr.,Sect.D, 60, 2004
1R4L
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BU of 1r4l by Molmil
Inhibitor Bound Human Angiotensin Converting Enzyme-Related Carboxypeptidase (ACE2)
Descriptor: (S,S)-2-{1-CARBOXY-2-[3-(3,5-DICHLORO-BENZYL)-3H-IMIDAZOL-4-YL]-ETHYLAMINO}-4-METHYL-PENTANOIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ...
Authors:Towler, P, Staker, B, Prasad, S.G, Menon, S, Ryan, D, Tang, J, Parsons, T, Fisher, M, Williams, D, Dales, N.A, Patane, M.A, Pantoliano, M.W.
Deposit date:2003-10-07
Release date:2004-02-03
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (3 Å)
Cite:ACE2 X-ray structures reveal a large hinge-bending motion important for inhibitor binding and catalysis.
J.Biol.Chem., 279, 2004

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