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7YC8
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BU of 7yc8 by Molmil
Cryo-EM structure of Tetrahymena ribozyme conformation 1 undergoing the first-step self-splicing
Descriptor: GUANOSINE-5'-TRIPHOSPHATE, RNA (388-MER)
Authors:Zhang, X, Li, S, Pintilie, G, Palo, M.Z, Zhang, K.
Deposit date:2022-07-01
Release date:2023-07-05
Last modified:2023-08-16
Method:ELECTRON MICROSCOPY (4.14 Å)
Cite:Snapshots of the first-step self-splicing of Tetrahymena ribozyme revealed by cryo-EM.
Nucleic Acids Res., 51, 2023
7YCG
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BU of 7ycg by Molmil
Cryo-EM structure of Tetrahymena ribozyme conformation 2 undergoing the first-step self-splicing
Descriptor: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, RNA (393-MER), ...
Authors:Zhang, X, Li, S, Pintilie, G, Palo, M.Z, Zhang, K.
Deposit date:2022-07-01
Release date:2023-07-05
Last modified:2023-08-16
Method:ELECTRON MICROSCOPY (3.18 Å)
Cite:Snapshots of the first-step self-splicing of Tetrahymena ribozyme revealed by cryo-EM.
Nucleic Acids Res., 51, 2023
7YCI
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BU of 7yci by Molmil
Cryo-EM structure of Tetrahymena ribozyme conformation 4 undergoing the first-step self-splicing
Descriptor: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, RNA (389-MER), ...
Authors:Zhang, X, Li, S, Pintilie, G, Palo, M.Z, Zhang, K.
Deposit date:2022-07-01
Release date:2023-07-05
Last modified:2023-08-16
Method:ELECTRON MICROSCOPY (2.98 Å)
Cite:Snapshots of the first-step self-splicing of Tetrahymena ribozyme revealed by cryo-EM.
Nucleic Acids Res., 51, 2023
7YCH
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BU of 7ych by Molmil
Cryo-EM structure of Tetrahymena ribozyme conformation 3 undergoing the first-step self-splicing
Descriptor: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, RNA (393-MER), ...
Authors:Zhang, X, Li, S, Pintilie, G, Palo, M.Z, Zhang, K.
Deposit date:2022-07-01
Release date:2023-07-05
Last modified:2023-08-16
Method:ELECTRON MICROSCOPY (3.09 Å)
Cite:Snapshots of the first-step self-splicing of Tetrahymena ribozyme revealed by cryo-EM.
Nucleic Acids Res., 51, 2023
3ZQH
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BU of 3zqh by Molmil
Structure of Tetracycline repressor in complex with inducer peptide- TIP3
Descriptor: 1,2-ETHANEDIOL, INDUCER PEPTIDE TIP3, TETRACYCLINE REPRESSOR PROTEIN CLASS B FROM TRANSPOSON TN10, ...
Authors:Sevvana, M, Goeke, D, Stoeckle, C, Kaspar, D, Grubmueller, S, Goetz, C, Wimmer, C, Berens, C, Klotzsche, M, Muller, Y.A, Hillen, W.
Deposit date:2011-06-09
Release date:2011-12-28
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:An Exclusive Alpha/Beta Code Directs Allostery in Tetr-Peptide Complexes.
J.Mol.Biol., 416, 2012
3ZQF
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BU of 3zqf by Molmil
Structure of Tetracycline repressor in complex with antiinducer peptide-TAP1
Descriptor: ANTI-INDUCER PEPTIDE TAP1, TETRACYCLINE REPRESSOR PROTEIN CLASS B FROM TRANSPOSON TN10, TETRACYCLINE REPRESSOR PROTEIN CLASS D
Authors:Sevvana, M, Goeke, D, Stoeckle, C, Kaspar, D, Grubmueller, S, Goetz, C, Wimmer, C, Berens, C, Klotzsche, M, Muller, Y.A, Hillen, W.
Deposit date:2011-06-09
Release date:2011-12-28
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.56 Å)
Cite:An Exclusive Alpha/Beta Code Directs Allostery in Tetr-Peptide Complexes.
J.Mol.Biol., 416, 2012
5TUF
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BU of 5tuf by Molmil
Crystal structure of tetracycline destructase Tet(50) in complex with anhydrotetracycline
Descriptor: 5A,6-ANHYDROTETRACYCLINE, FLAVIN-ADENINE DINUCLEOTIDE, SULFATE ION, ...
Authors:Park, J, Tolia, N.H.
Deposit date:2016-11-06
Release date:2017-05-10
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Plasticity, dynamics, and inhibition of emerging tetracycline resistance enzymes.
Nat. Chem. Biol., 13, 2017
2NS8
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BU of 2ns8 by Molmil
How an in vitro selected peptide mimics the antibiotic tetracycline to induce TET repressor
Descriptor: 16 residue peptide Tip (Transcription inducing peptide), Tetracycline repressor protein
Authors:Luckner, S.R, Klotzsche, M, Berens, C, Hillen, W, Muller, Y.A.
Deposit date:2006-11-03
Release date:2007-07-24
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:How an agonist peptide mimics the antibiotic tetracycline to induce Tet-repressor
J.Mol.Biol., 368, 2007
3ZQG
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BU of 3zqg by Molmil
Structure of Tetracycline repressor in complex with antiinducer peptide-TAP2
Descriptor: ANTI-INDUCER PEPTIDE TAP2, TETRACYCLINE REPRESSOR PROTEIN CLASS B FROM TRANSPOSON TN10, TETRACYCLINE REPRESSOR PROTEIN CLASS D
Authors:Sevvana, M, Goeke, D, Stoeckle, C, Kaspar, D, Grubmueller, S, Goetz, C, Wimmer, C, Berens, C, Klotzsche, M, Muller, Y.A, Hillen, W.
Deposit date:2011-06-09
Release date:2011-12-28
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:An Exclusive Alpha/Beta Code Directs Allostery in Tetr-Peptide Complexes.
J.Mol.Biol., 416, 2012
8ER0
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BU of 8er0 by Molmil
X-ray crystal structure of Tet(X6) bound to anhydrotetracycline
Descriptor: 5A,6-ANHYDROTETRACYCLINE, FLAVIN-ADENINE DINUCLEOTIDE, Flavin-dependent monooxygenase
Authors:Kumar, H, Tolia, N.H.
Deposit date:2022-10-11
Release date:2023-04-26
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of anhydrotetracycline-bound Tet(X6) reveals the mechanism for inhibition of type 1 tetracycline destructases.
Commun Biol, 6, 2023
5D9Y
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BU of 5d9y by Molmil
Crystal structure of TET2-5fC complex
Descriptor: DNA (5'-D(*AP*CP*TP*GP*TP*(5FC)P*GP*AP*AP*GP*CP*T)-3'), DNA (5'-D(*AP*GP*CP*TP*TP*CP*GP*AP*CP*AP*GP*T)-3'), FE (III) ION, ...
Authors:Hu, L, Cheng, J, Rao, Q, Li, Z, Li, J, Xu, Y.
Deposit date:2015-08-19
Release date:2015-11-04
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.971 Å)
Cite:Structural insight into substrate preference for TET-mediated oxidation.
Nature, 527, 2015
5DEU
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BU of 5deu by Molmil
Crystal structure of TET2-5hmC complex
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, DNA (5'-D(*AP*CP*CP*AP*CP*(5HC)P*GP*GP*TP*GP*GP*T)-3'), ...
Authors:Hu, L, Cheng, J, Rao, Q, Li, Z, Li, J, Xu, Y.
Deposit date:2015-08-26
Release date:2015-11-04
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.801 Å)
Cite:Structural insight into substrate preference for TET-mediated oxidation.
Nature, 527, 2015
1QPI
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BU of 1qpi by Molmil
CRYSTAL STRUCTURE OF TETRACYCLINE REPRESSOR/OPERATOR COMPLEX
Descriptor: DNA (5'-D(*CP*CP*TP*AP*TP*CP*AP*AP*TP*GP*AP*TP*AP*GP*A)-3'), DNA (5'-D(*TP*CP*TP*AP*TP*CP*AP*TP*TP*GP*AP*TP*AP*GP*G)-3'), IMIDAZOLE, ...
Authors:Orth, P, Schnappinger, D, Hillen, W, Saenger, W, Hinrichs, W.
Deposit date:1999-05-25
Release date:2000-02-28
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis of gene regulation by the tetracycline inducible Tet repressor-operator system.
Nat.Struct.Biol., 7, 2000
2P2A
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BU of 2p2a by Molmil
X-ray structure of the GluR2 ligand binding core (S1S2J) in complex with 2-Bn-tet-AMPA at 2.26A resolution
Descriptor: 2-AMINO-3-[3-HYDROXY-5-(2-BENZYL-2H-5-TETRAZOLYL)-4-ISOXAZOLYL]-PROPIONIC ACID, GLUTAMIC ACID, Glutamate receptor 2, ...
Authors:Frydenvang, K, Kastrup, J.S, Gajhede, M.
Deposit date:2007-03-07
Release date:2007-06-19
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:A tetrazolyl-substituted subtype-selective AMPA receptor agonist.
J.Med.Chem., 50, 2007
2XGE
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BU of 2xge by Molmil
Crystal structure of a designed heterodimeric variant T-A(A)B of the tetracycline repressor
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, SODIUM ION, ...
Authors:Stiebritz, M.T, Wengrzik, S, Richter, J.P, Muller, Y.A.
Deposit date:2010-06-03
Release date:2010-09-22
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Computational Design of a Chain-Specific Tetracycline Repressor Heterodimer.
J.Mol.Biol., 403, 2010
2XGD
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BU of 2xgd by Molmil
Crystal structure of a designed homodimeric variant T-A(L)A(L) of the tetracycline repressor
Descriptor: CHLORIDE ION, TETRACYCLINE REPRESSOR PROTEIN CLASS B FROM TRANSPOSON TN10, TETRACYCLINE REPRESSOR PROTEIN CLASS D
Authors:Stiebritz, M.T, Wengrzik, S, Richter, J.P, Muller, Y.A.
Deposit date:2010-06-03
Release date:2010-09-22
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Computational Design of a Chain-Specific Tetracycline Repressor Heterodimer.
J.Mol.Biol., 403, 2010
5EXH
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BU of 5exh by Molmil
Crystal structure of mTET3-CXXC domain in complex with 5-carboxylcytosine DNA at 1.3 Angstroms resolution.
Descriptor: DNA (5'-D(*GP*AP*AP*TP*CP*(1CC)P*GP*GP*AP*TP*TP*C)-3'), Methylcytosine dioxygenase TET3, ZINC ION
Authors:Song, J.
Deposit date:2015-11-23
Release date:2016-02-03
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Tet3 Reads 5-Carboxylcytosine through Its CXXC Domain and Is a Potential Guardian against Neurodegeneration.
Cell Rep, 14, 2016
2ABM
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BU of 2abm by Molmil
Crystal Structure of Aquaporin Z Tetramer Reveals both Open and Closed Water-conducting Channels
Descriptor: (1S)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PENTANOYLOXY)METHYL]ETHYL OCTANOATE, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, 2-O-octyl-beta-D-glucopyranose, ...
Authors:Jiang, J, Daniels, B.V, Fu, D.
Deposit date:2005-07-15
Release date:2005-09-20
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Crystal Structure of AqpZ Tetramer Reveals Two Distinct Arg-189 Conformations Associated with Water Permeation through the Narrowest Constriction of the Water-conducting Channel.
J.Biol.Chem., 281, 2006
1THC
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BU of 1thc by Molmil
CRYSTAL STRUCTURE DETERMINATION AT 2.3A OF HUMAN TRANSTHYRETIN-3',5'-DIBROMO-2',4,4',6-TETRA-HYDROXYAURONE COMPLEX
Descriptor: 3',5'-DIBROMO-2',4,4',6'-TETRAHYDROXY AURONE, TRANSTHYRETIN
Authors:Ciszak, E, Cody, V, Luft, J.R.
Deposit date:1992-04-20
Release date:1993-07-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure determination at 2.3-A resolution of human transthyretin-3',5'-dibromo-2',4,4',6-tetrahydroxyaurone complex.
Proc.Natl.Acad.Sci.USA, 89, 1992
4UOV
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BU of 4uov by Molmil
The structure of a tetrameric alpha-carbonic anhydrase from Thermovibrio ammonificans reveals a core formed around intermolecular disulfides, which contribute to its thermostability.
Descriptor: 1-METHOXY-2-[2-(2-METHOXY-ETHOXY]-ETHANE, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3,6,9,12,15,18,21,24,27,30,33,36,39-TRIDECAOXAHENTETRACONTANE-1,41-DIOL, ...
Authors:James, P, Isupov, M, Sayer, C, Berg, S, Lioliou, M, Kotlar, H, Littlechild, J.
Deposit date:2014-06-10
Release date:2014-10-15
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:The Structure of a Tetrameric [Alpha]-Carbonic Anhydrase from Thermovibrio Ammonificans Reveals a Core Formed Around Intermolecular Disulfides that Contribute to its Thermostability
Acta Crystallogr.,Sect.D, 70, 2014
1FP7
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BU of 1fp7 by Molmil
MONOVALENT CATION BINDING SITES IN N10-FORMYLTETRAHYDROFOLATE SYNTHETASE FROM MOORELLA THERMOACETICA
Descriptor: FORMATE--TETRAHYDROFOLATE LIGASE, POTASSIUM ION, SULFATE ION
Authors:Radfar, R, Leaphart, A, Brewer, J.M, Minor, W, Odom, J.D.
Deposit date:2000-08-30
Release date:2001-08-30
Last modified:2022-04-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Cation binding and thermostability of FTHFS monovalent cation binding sites and thermostability of N10-formyltetrahydrofolate synthetase from Moorella thermoacetica.
Biochemistry, 39, 2000
5KHD
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BU of 5khd by Molmil
Structure of 1.75 A BldD C-domain-c-di-GMP complex
Descriptor: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), DNA-binding protein
Authors:Schumacher, M.
Deposit date:2016-06-14
Release date:2016-06-29
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.7501 Å)
Cite:Tetrameric c-di-GMP mediates effective transcription factor dimerization to control Streptomyces development.
Cell, 158, 2014
6VUM
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BU of 6vum by Molmil
Structure of nevanimibe-bound human tetrameric ACAT1
Descriptor: CHOLESTEROL, COENZYME A, OLEIC ACID, ...
Authors:Li, X, Long, T.
Deposit date:2020-02-16
Release date:2020-05-13
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.67 Å)
Cite:Structure of nevanimibe-bound tetrameric human ACAT1.
Nature, 581, 2020
5FHO
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BU of 5fho by Molmil
Crystal structure of the GluA2 ligand-binding domain (S1S2J) in complex with (S)-2-Amino-3-(5-(2-(3-chlorobenzyl)-2H-tetrazol-5-yl)-3-hydroxyisoxazol-4-yl)propanoic acid at 2.3 A resolution
Descriptor: (1S)-1-carboxy-2-(5-{2-[(3-chlorophenyl)methyl]-2H-tetrazol-5-yl}-3-oxo-2,3-dihydro-1,2-oxazol-4-yl)ethan-1-aminium, 1,2-ETHANEDIOL, CHLORIDE ION, ...
Authors:Frydenvang, K, Kastrup, J.S.
Deposit date:2015-12-22
Release date:2016-03-02
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Tweaking Subtype Selectivity and Agonist Efficacy at (S)-2-Amino-3-(3-hydroxy-5-methyl-isoxazol-4-yl)propionic acid (AMPA) Receptors in a Small Series of BnTetAMPA Analogues.
J.Med.Chem., 59, 2016
4OAY
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BU of 4oay by Molmil
BldD CTD-c-di-GMP complex
Descriptor: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), DNA-binding protein
Authors:Schumacher, M.A, Tschowri, N, Buttner, M, Brennan, R.G.
Deposit date:2014-01-06
Release date:2014-11-19
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Tetrameric c-di-GMP mediates effective transcription factor dimerization to control Streptomyces development.
Cell(Cambridge,Mass.), 158, 2014

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