6VUM

Structure of nevanimibe-bound human tetrameric ACAT1

Summary for 6VUM

• Entry DOI: 10.2210/pdb6vum/pdb
• EMDB information: 21390
• Descriptor: Sterol O-acyltransferase 1, OLEIC ACID, CHOLESTEROL, ... (6 entities in total)
• Functional Keywords: cholesterol, cholesteryl ester, acyltransferase, mboat, membrane protein
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 4
• Total formula weight: 273486.88

Authors

Li, X.,Long, T. (deposition date: 2020-02-16, release date: 2020-05-13, Last modification date: 2024-03-06)

• Primary citation: Long, T.,Sun, Y.,Hassan, A.,Qi, X.,Li, X.; Structure of nevanimibe-bound tetrameric human ACAT1.; Nature, 581:339-343, 2020; PubMed: 32433613; DOI: 10.1038/s41586-020-2295-8

Experimental method

ELECTRON MICROSCOPY (3.67 Å)