PDB: 278 resultsInfo pagesStatus searchChemie searchBIRD

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4F01	Crystal structure of an artificial dimeric DnaK complex Descriptor: Chaperone protein DnaK Authors: Zahn, M, Straeter, N. Deposit date: 2012-05-03 Release date: 2013-04-17 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Structural Studies on the Forward and Reverse Binding Modes of Peptides to the Chaperone DnaK. J.Mol.Biol., 425, 2013
4EZT	Crystal structure of the substrate binding domain of E.coli DnaK in complex with heliocin (residues 14 to 21) Descriptor: Chaperone protein DnaK, Heliocin Authors: Zahn, M, Straeter, N. Deposit date: 2012-05-03 Release date: 2013-04-17 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2 Å) Cite: Structural Studies on the Forward and Reverse Binding Modes of Peptides to the Chaperone DnaK. J.Mol.Biol., 425, 2013
4EZR	Crystal structure of the substrate binding domain of E.coli DnaK in complex with the C-terminal part of drosocin (residues 12 to 19) Descriptor: Chaperone protein DnaK, Drosocin Authors: Zahn, M, Straeter, N. Deposit date: 2012-05-03 Release date: 2013-04-17 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structural Studies on the Forward and Reverse Binding Modes of Peptides to the Chaperone DnaK. J.Mol.Biol., 425, 2013
4EZW	Crystal structure of the substrate binding domain of E.coli DnaK in complex with the designer peptide NRLLLTG Descriptor: Chaperone protein DnaK, SULFATE ION, synthetic peptide NRLLLTG Authors: Zahn, M, Straeter, N. Deposit date: 2012-05-03 Release date: 2013-04-17 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Structural Studies on the Forward and Reverse Binding Modes of Peptides to the Chaperone DnaK. J.Mol.Biol., 425, 2013
4EZO	Crystal structure of the substrate binding domain of E.coli DnaK in complex with PR-39 (residues 1 to 15) Descriptor: Antibacterial protein PR-39, Chaperone protein DnaK, SULFATE ION Authors: Zahn, M, Straeter, N. Deposit date: 2012-05-03 Release date: 2013-04-17 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structural Studies on the Forward and Reverse Binding Modes of Peptides to the Chaperone DnaK. J.Mol.Biol., 425, 2013
4EZZ	Crystal structure of the substrate binding domain of E.coli DnaK in complex with the designer peptide ELPLVKI Descriptor: Chaperone protein DnaK, synthetic peptide ELPLVKI Authors: Zahn, M, Straeter, N. Deposit date: 2012-05-03 Release date: 2013-04-17 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Structural Studies on the Forward and Reverse Binding Modes of Peptides to the Chaperone DnaK. J.Mol.Biol., 425, 2013
4EZQ	Crystal structure of the substrate binding domain of E.coli DnaK in complex with the C-terminal part of pyrrhocoricin (residues 12 to 20) Descriptor: Chaperone protein DnaK, Pyrrhocoricin Authors: Zahn, M, Straeter, N. Deposit date: 2012-05-03 Release date: 2013-04-17 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2 Å) Cite: Structural Studies on the Forward and Reverse Binding Modes of Peptides to the Chaperone DnaK. J.Mol.Biol., 425, 2013
4EZS	Crystal structure of the substrate binding domain of E.coli DnaK in complex with metchnikowin (residues 20 to 26) Descriptor: Chaperone protein DnaK, Metchnikowin, SULFATE ION Authors: Zahn, M, Straeter, N. Deposit date: 2012-05-03 Release date: 2013-04-24 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structural studies of DnaK in complex with proline rich antimicrobial peptides reveal two different peptide binding modes To be Published
4EZY	Crystal structure of the substrate binding domain of E.coli DnaK in complex with the designer peptide NRLILTG Descriptor: Chaperone protein DnaK, SULFATE ION, synthetic peptide NRLILTG Authors: Zahn, M, Straeter, N. Deposit date: 2012-05-03 Release date: 2013-04-17 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Structural Studies on the Forward and Reverse Binding Modes of Peptides to the Chaperone DnaK. J.Mol.Biol., 425, 2013
4EZN	Crystal structure of the substrate binding domain of E.coli DnaK in complex with pyrrhocoricin Descriptor: Chaperone protein DnaK, Pyrrhocoricin Authors: Zahn, M, Straeter, N. Deposit date: 2012-05-03 Release date: 2013-04-17 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Structural Studies on the Forward and Reverse Binding Modes of Peptides to the Chaperone DnaK. J.Mol.Biol., 425, 2013
4EZX	Crystal structure of the substrate binding domain of E.coli DnaK in complex with the designer peptide NRLMLTG Descriptor: Chaperone protein DnaK, SULFATE ION, synthetic peptide NRLMLTG Authors: Zahn, M, Straeter, N. Deposit date: 2012-05-03 Release date: 2013-04-17 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Structural Studies on the Forward and Reverse Binding Modes of Peptides to the Chaperone DnaK. J.Mol.Biol., 425, 2013
4FL9	Crystal Structure of bovine hsc70(aa1-554)E213A/D214A at 1.9A Resolution Descriptor: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, Heat shock cognate 71 kDa protein, trimethylamine oxide Authors: Grimm, C. Deposit date: 2012-06-14 Release date: 2013-10-02 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.901 Å) Cite: Crystal Structure of bovine hsc70(aa1-554)E213A/D214A at 1.9A Resolution TO BE PUBLISHED
4FSV	Crystal structure of a heat shock 70kDa protein 2 (HSPA2) from Homo sapiens at 1.80 A resolution Descriptor: Heat shock-related 70 kDa protein 2 Authors: Joint Center for Structural Genomics (JCSG), Partnership for T-Cell Biology (TCELL) Deposit date: 2012-06-27 Release date: 2012-07-18 Last modified: 2023-02-01 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Crystal structure of a heat shock 70kDa protein 2 (HSPA2) from Homo sapiens at 1.80 A resolution To be published
5AQX	Fragment-based screening of HSP70 sheds light on the functional role of ATP-binding site residues Descriptor: (1R,2S,3R,5R)-3-((5-(benzyloxy)quinazolin-4-yl)amino)-5-(hydroxymethyl)cyclopentane-1,2-diol, CHLORIDE ION, DIMETHYL SULFOXIDE, ... Authors: Jones, A.M, Westwood, I.M, Osborne, J.D, Matthews, T.P, Cheeseman, M.D, Rowlands, M.G, Jeganathan, F, Burke, R, Lee, D, Kadi, N, Liu, M, Richards, M, McAndrew, C, Yahya, N, Dobson, S.E, Jones, K, Workman, P, Collins, I, van Montfort, R.L.M. Deposit date: 2015-09-22 Release date: 2016-10-05 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.12 Å) Cite: A fragment-based approach applied to a highly flexible target: Insights and challenges towards the inhibition of HSP70 isoforms. Sci Rep, 6, 2016
5AQY	Fragment-based screening of HSP70 sheds light on the functional role of ATP-binding site residues Descriptor: 1,2-ETHANEDIOL, ADENOSINE, DIMETHYL SULFOXIDE, ... Authors: Jones, A.M, Westwood, I.M, Osborne, J.D, Matthews, T.P, Cheeseman, M.D, Rowlands, M.G, Jeganathan, F, Burke, R, Lee, D, Kadi, N, Liu, M, Richards, M, McAndrew, C, Yahya, N, Dobson, S.E, Jones, K, Workman, P, Collins, I, van Montfort, R.L.M. Deposit date: 2015-09-22 Release date: 2016-10-05 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.56 Å) Cite: A fragment-based approach applied to a highly flexible target: Insights and challenges towards the inhibition of HSP70 isoforms. Sci Rep, 6, 2016
5BPM	Crystal structure of unhydrolyzed ATP bound human Hsp70 NBD double mutant E268Q+R272K. Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, Heat shock 70 kDa protein 1A, ... Authors: Narayanan, D, Engh, R.A. Deposit date: 2015-05-28 Release date: 2016-09-14 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.83 Å) Cite: Nucleotide binding to variants of the HSP70-NBD. To Be Published
5BPL	Crystal structure of ADP and Pi bound human Hsp70 NBD mutant R272K. Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, ... Authors: Narayanan, D, Engh, R.A. Deposit date: 2015-05-28 Release date: 2016-09-14 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.93 Å) Cite: Nucleotide binding to variants of the HSP70-NBD. To Be Published
5BN8	Crystal structure of nucleotide-free human Hsp70 NBD. Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION, Heat shock 70 kDa protein 1A, ... Authors: Narayanan, D, Engh, R.A. Deposit date: 2015-05-25 Release date: 2016-09-14 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.34 Å) Cite: Nucleotide binding to variants of the HSP70-NBD. To Be Published
5BPN	Crystal structure of nucleotide-free human Hsp70 NBD double mutant E268Q+R272K. Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, Heat shock 70 kDa protein 1A, ... Authors: Narayanan, D, Engh, R.A. Deposit date: 2015-05-28 Release date: 2016-09-14 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Nucleotide binding to variants of the HSP70-NBD. To Be Published
5BN9	Crystal structure of ADP bound human Hsp70 NBD mutant R272K. Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, ... Authors: Narayanan, D, Engh, R.A. Deposit date: 2015-05-25 Release date: 2016-09-14 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.689 Å) Cite: Nucleotide binding to variants of the HSP70-NBD. To Be Published
5AQZ	HSP72 with adenosine-derived inhibitor Descriptor: 1,2-ETHANEDIOL, HEAT SHOCK 70 KDA PROTEIN 1A, SANGIVAMYCIN Authors: Cheeseman, M.D, Westwood, I.M, Barbeau, O, Rowlands, M.G, Jones, A.M, Jeganathan, F, Burke, R, Dobson, S.E, Workman, P, Collins, I, van Montfort, R.L.M, Jones, K. Deposit date: 2015-09-22 Release date: 2016-05-11 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Exploiting Protein Conformational Change to Optimize Adenosine-Derived Inhibitors of Hsp70. J.Med.Chem., 59, 2016
5AQW	Fragment-based screening of HSP70 sheds light on the functional role of ATP-binding site residues Descriptor: (1S,2R,3R,5R)-3-(hydroxymethyl)-5-(quinazolin-4-ylamino)cyclopentane-1,2-diol, (2S,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, 1,2-ETHANEDIOL, ... Authors: Jones, A.M, Westwood, I.M, Osborne, J.D, Matthews, T.P, Cheeseman, M.D, Rowlands, M.G, Jeganathan, F, Burke, R, Lee, D, Kadi, N, Liu, M, Richards, M, McAndrew, C, Yahya, N, Dobson, S.E, Jones, K, Workman, P, Collins, I, van Montfort, R.L.M. Deposit date: 2015-09-22 Release date: 2016-10-05 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.53 Å) Cite: A fragment-based approach applied to a highly flexible target: Insights and challenges towards the inhibition of HSP70 isoforms. Sci Rep, 6, 2016
5AR0	HSP72 with adenosine-derived inhibitor Descriptor: (2R,3R,4S,5R)-2-(6-amino-8-((quinolin-7-ylmethyl)amino)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol, CHLORIDE ION, DIMETHYL SULFOXIDE, ... Authors: Cheeseman, M.D, Westwood, I.M, Barbeau, O, Rowlands, M.G, Jones, A.M, Jeganathan, F, Burke, R, Dobson, S.E, Workman, P, Collins, I, van Montfort, R.L.M, Jones, K. Deposit date: 2015-09-22 Release date: 2016-05-11 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Exploiting Protein Conformational Change to Optimize Adenosine-Derived Inhibitors of Hsp70. J.Med.Chem., 59, 2016
8OO0	Chaetomium thermophilum Methionine Aminopeptidase 2 autoproteolysis product at the 80S ribosome Descriptor: 18S rRNA, 28S rRNA, 40S ribosomal protein S0, ... Authors: Klein, M.A, Wild, K, Kisonaite, M, Sinning, I. Deposit date: 2023-04-04 Release date: 2024-02-21 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Methionine aminopeptidase 2 and its autoproteolysis product have different binding sites on the ribosome. Nat Commun, 15, 2024
7X3K	Cryo-EM structure of RAC in the State C2 RNC-RAC complex Descriptor: Ribosome-associated complex subunit SSZ1, Zuotin Authors: Chen, Y, Gao, N. Deposit date: 2022-03-01 Release date: 2022-06-29 Method: ELECTRON MICROSCOPY (6 Å) Cite: Structural remodeling of ribosome associated Hsp40-Hsp70 chaperones during co-translational folding. Nat Commun, 13, 2022

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