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4H5N

HSC70 NBD with PO4, Na, Cl

Summary for 4H5N
Entry DOI10.2210/pdb4h5n/pdb
Related4H5R 4H5T 4H5V 4H5W
DescriptorHeat shock cognate 71 kDa protein, PHOSPHATE ION, CHLORIDE ION, ... (6 entities in total)
Functional Keywordsnucleotide binding domain, transcription
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm: P11142
Total number of polymer chains2
Total formula weight85861.24
Authors
Stec, B. (deposition date: 2012-09-18, release date: 2014-03-19, Last modification date: 2023-09-20)
Primary citationZhang, Z.,Cellitti, J.,Teriete, P.,Pellecchia, M.,Stec, B.
New crystal structures of HSC-70 ATP binding domain confirm the role of individual binding pockets and suggest a new method of inhibition.
Biochimie, 108:186-192, 2015
Cited by
PubMed: 25433210
DOI: 10.1016/j.biochi.2014.11.012
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.86 Å)
Structure validation

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